The DOI matches its Crossref record; 233 of the 233 references it cites were found in a registry or an index.
Periodontal Inflammation and Systemic Diseases: An Overview
Open accessAbstract
Periodontitis is a common inflammatory disease of infectious origins that often evolves into a chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis has gained relevance since it has been shown that it can develop into a systemic condition characterized by unresolved hyper-inflammation, disruption of the innate and adaptive immune system, dysbiosis of the oral, gut and other location's microbiota and other system-wide alterations that may cause, coexist or aggravate other health issues associated to elevated morbi-mortality. The relationships between the infectious, immune, inflammatory, and systemic features of periodontitis and its many related diseases are far from being fully understood and are indeed still debated. However, to date, a large body of evidence on the different biological, clinical, and policy-enabling sources of information, is available. The aim of the present work is to summarize many of these sources of information and contextualize them under a systemic inflammation framework that may set the basis to an integral vision, useful for basic, clinical, and therapeutic goals.
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Citations
Cites
Periodontitis: from microbial immune subversion to systemic inflammation
Hajishengallis, G. (2015) · Nature Reviews Immunology · doi:10.1038/nri3785 · Cited by 3,046 · cited 3×
“This may happen via periodontitis-associated inflammatory cascades: locally produced pro-inflammatory mediators enter into systemic circulation, thus becoming able to affect distant organs disrupting inflammatory state equilibria (Hajishengallis, 2015).”
BackgroundKinane, D. F., Stathopoulou, P. G., & Papapanou, P. N. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.38 · Cited by 2,724
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease
Turner, M. D., Nedjai, B., Hurst, T., & Pennington, D. J. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.05.014 · Cited by 2,162
The cytokine storm and COVID-19
Hu, B., Huang, S., & Yin, L. (2021) · Journal of Medical Virology · doi:10.1002/jmv.26232 · Cited by 1,655
Targeting IL-17 and TH17 cells in chronic inflammation
Miossec, P., & Kolls, J. K. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3794 · Cited by 1,414
Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
Tang, Y., Liu, J., Zhang, D., Xu, Z., Ji, J., & Wen, C. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01708 · Cited by 1,094
Valsesia, A., Wang, Q.-P., Gheldof, N., Carayol, J., Ruffieux, H., Clark, T., Shenton, V., Oyston, L. J., Lefebvre, G., Metairon, S., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-08492-8 · Cited by 1,073
Th17 and regulatory T cell balance in autoimmune and inflammatory diseases
Noack, M., & Miossec, P. (2014) · Autoimmunity Reviews · doi:10.1016/j.autrev.2013.12.004 · Cited by 932
Borish, L. C., & Steinke, J. W. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2003.108 · Cited by 879
Periodontitis: A Multifaceted Disease of Tooth-Supporting Tissues
Könönen, E., Gursoy, M., & Gursoy, U. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081135 · Cited by 862
Cited by
Deciphering mechanisms and implications of bacterial translocation in human health and disease
Jin, S., Wetzel, D., & Schirmer, M. (2022) · Current Opinion in Microbiology · doi:10.1016/j.mib.2022.102147 · Cited by 39
Metadata
- Authors
- Martínez-García, M., & Hernández-Lemus, E.
- Venue
- Frontiers in Physiology
- Publisher
- Frontiers Media SA
- Published
- 2021-10-27
- Volume
- 12
- Pages
- 709438-709438
- ISSN
- 1664-042X (ISSN-L)
- OpenAlex
- W3210311404
- Cited by
- 512
- References
- 233
- FWCI
- 44.78
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
