OBTAINING SCARLET SAGE (SALVIA COCCINEA) EXTRACT THROUGH HOMOGENIZER- AND ULTRASOUND-ASSISTED EXTRACTION METHODS
Abstract
Scarlet sage (Salvia coccinea) leaves were extracted with water, ethanol, methanol, and aqueous mixtures of those solvents by homogenizer-assisted extraction (HAE) and ultrasound-assisted extraction (UAE) methods, which are novel technologies used for this purpose. The best results were compared with those obtained by the conventional Soxhlet method (SM). Total phenolic content was expressed in gallic acid equivalent (GAE) per g of dried leaf. Free radical scavenging activity for the antioxidant capacity was tested by 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical. The greatest amount of extraction was achieved by pure water with the value of 368.87 mg/g dried matter and the highest total phenolic content was observed by 100% methanol as 43.18 mg-GAE/g dried matter, both obtained by the HAE method. The mint leaves extracted by SM exhibited the highest antioxidant capacity, with a value of 90.55% for inhibition of DPPH radical.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Bilgin et al. found that UAE shortened the extraction time and reduced solvent consumption for scarlet sage extract compared to homogenizer assisted extraction.
“Bilgin et al. [46] obtained scarlet sage (Salvia Coccinea) extract using homogenizer assisted extraction and UAE respectively. The findings indicated that UAE shortened the extraction time and reduced the solvent consumption.”
From A comprehensive review of ultrasonic assisted extraction (UAE) for bioactive components: Principles, advantages, equipment, and combined technologies (2023) · cites this paper as [46]
Cites
Essential oils: Their antibacterial properties and potential applications in foods—A review
Burt, S. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.03.022 · Cited by 10,488 · see citing works
Antioxidant activity of plant extracts containing phenolic compounds
Kähkönen, M. P., Hopia, A. I., Vuorela, H. J., Rauha, J.-P., Pihlaja, K., Kujala, T. S., & Heinonen, M. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990146l · Cited by 3,854 · cited 2× · see citing works
“According to many researchers (Corrales et al., 2008; Heinonen et al., 1998; Kähkönen et al., 1999; Velioglu et al., 1998), different compounds with antioxidant activity might have different responses in the Folin-Ciocalteau method.”
BackgroundAntioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products
Velioğlu, Y. S., Mazza, G., Gao, L., & Oomah, B. D. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9801973 · Cited by 3,853 · see citing works
Recent advances in extraction of nutraceuticals from plants
Wang, L., & Weller, C. L. (2006) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2005.12.004 · Cited by 2,046 · see citing works
Screening of Plant Extracts for Antioxidant Activity: a Comparative Study on Three Testing Methods
Koleva, I. I., van Beek, T. A., Linssen, J. P. H., de Groot, C. P. G. M., & Evstatieva, L. N. (2002) · Phytochemical Analysis · doi:10.1002/pca.611 · Cited by 1,785 · see citing works
Corrales, M., Toepfl, S., Butz, P., Knorr, D., & Tauscher, B. (2007) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2007.06.002 · Cited by 773 · see citing works
Supercritical fluid extraction in herbal and natural product studies — a practical review
Lang, Q. (2001) · Talanta · doi:10.1016/s0039-9140(00)00557-9 · Cited by 667 · see citing works
Sources of natural phenolic antioxidants
Bitas, D. (2006) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2006.04.004 · Cited by 667 · see citing works
Güllüce, M., Sahin, F., Sökmen, M., Özer, H., Daferera, D. J., Sökmen, A., Polissiou, M. G., Adıgüzel, A., & Ozkan, H. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.10.061 · Cited by 627 · see citing works
Antioxidant Activity of Citrus Limonoids, Flavonoids, and Coumarins
Yu, J. M., Wang, L., Walzem, R. L., Miller, E. G., Pike, L. M., & Patil, B. S. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0484632 · Cited by 454 · see citing works
Güllüce, M., Şahi̇n, F., & Sökmen, M. (2007) · Cited by 397 · see citing works
Durling, N. E., Catchpole, O. J., Grey, J. B., Webby, R. F., MITCHELL, K., Foo, L. Y., & Perry, N. B. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.03.050 · Cited by 394 · see citing works
Antioxidant Activity of Berry and Fruit Wines and Liquors
Heinonen, M., Lehtonen, P., & Hopia, A. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf970489o · Cited by 356 · see citing works
Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability
Arabshahi-Delouee, S., Devi, D. V., & Urooj, A. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2005.11.014 · Cited by 259 · see citing works
Biotransformations of phenolic compounds in Olea europaea L.
Ryan, D., Antolovich, M., Prenzler, P. D., Robards, K., & Lavee, S. (2002) · Scientia Horticulturae · doi:10.1016/s0304-4238(01)00287-4 · Cited by 252 · see citing works
Grigonis, D., Venskutonis, P. R., Sivik, B., Sandahl, M., & Eskilsson, C. S. (2004) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2004.08.006 · Cited by 166 · see citing works
Supercritical fluid extraction of phenol compounds from olive leaves
Floch, F. L., Tena, M. T., Ríos, Á., & Valcárcel, M. (1998) · Talanta · doi:10.1016/s0039-9140(97)00375-5 · Cited by 161 · see citing works
Veličković, D. T., Milenović, D. M., Ristic, M. S., et al. (2005) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2005.02.002 · Cited by 141 · see citing works
Malik, N. S. A., & Bradford, J. M. (2006) · Scientia Horticulturae · doi:10.1016/j.scienta.2006.07.016 · Cited by 139 · see citing works
Supercritical fluid extraction of pesticides in foods
Lehotay, S. J. (1997) · Journal of Chromatography A · doi:10.1016/s0021-9673(97)00461-5 · Cited by 139 · see citing works
Tena, M. T., Valcárcel, M., Hidalgo, P. J., & Ubera, J. L. (1997) · Analytical Chemistry · doi:10.1021/ac960506t · Cited by 114 · see citing works
Extraction of antioxidants from sweet Thai tamarind seed coat––preliminary experiments
Luengthanaphol, S., Mongkholkhajornsilp, D., Douglas, S., Douglas, P. L., Pengsopa, L.-I., & Pongamphai, S. (2003) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2003.07.006 · Cited by 94 · see citing works
Farag, R. S., Mahmoud, E. A., & Basuny, A. M. (2006) · International Journal of Food Science & Technology · doi:10.1111/j.1365-2621.2006.01374.x · Cited by 84 · see citing works
Arumugam, P., Ramamurthy, P., Santhiya, S. T., et al. (2006) · PubMed · Cited by 75 · see citing works
Casas, L., Mantell, C., Rodríguez, M., et al. (2006) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2006.09.001 · Cited by 63 · see citing works
Phenolic Compounds and their Effects on Human Health
Vermerris, W., & Nicholson, R. L. (2007) · Springer eBooks · doi:10.1007/978-1-4020-5164-7_7 · Cited by 52 · see citing works
Influence of crude olive leaf juice on rat liver and kidney functions
Farag, R. S., Mahmoud, E. A., Basuny, A. M., et al. (2006) · International Journal of Food Science & Technology · doi:10.1111/j.1365-2621.2006.01093.x · Cited by 34 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Shen, L., Pang, S., Zhong, M., Sun, Y., Qayum, A., Liu, Y., Rashid, A., Xu, B., Liang, Q., Ma, H., et al. (2023) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2023.106646 · Cited by 892 · see citing works
“Bilgin et al. [46] obtained scarlet sage (Salvia Coc-cinea) extract using homogenizer assisted extraction and UAE respectively.”
MethodStudy on optimum extraction conditions for olive leaf extracts rich in polyphenol and flavonoid
Şahin, S., İlbay, Z., & Kırbaşlar, Ş. İ. (2015) · Separation Science and Technology · doi:10.1080/01496395.2014.966203 · Cited by 32 · see citing works
- Authors
- Bilgin, M., Sahin, S., Dramur, M. U., & Sevgili, L. M.
- Affiliations
- Istanbul University (TR)
- Corresponding author
- Bilgin, Mehmet
- Venue
- Chemical Engineering Communications
- Publisher
- Informa UK Limited
- Published
- 2013-09-02
- Volume
- 200
- Issue
- 9
- Pages
- 1197-1209
- ISSN
- 0098-6445 (ISSN-L)
- 1563-5201
- OpenAlex
- W1995673237
- Cited by
- 28
- References
- 27
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 2 · 2021: 1 · 2020: 4 · 2019: 2 · 2018: 6 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 1
- FWCI
- 1.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Engineering Communications (publishedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- Salvia coccinea, ultrasound-assisted extraction, Soxhlet extraction, leaf extract, solvent extraction, total phenolic content, antioxidant capacity, DPPH radical scavenging, extraction yield
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review