The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
SPERM DNA FRAGMENTATION IS INCREASED IN COUPLES WITH UNEXPLAINED RECURRENT PREGNANCY LOSS
Abstract
Previous studies have indicated that sperm quality may be related to unexplained recurrent pregnancy loss. This study evaluated the degree of sperm DNA fragmentation using the TUNEL assay on sperm from 24 couples with unexplained recurrent pregnancy loss (RPL) compared to sperm from 2 control groups: donors of known fertility and unscreened men from the general population. The percentage of sperm staining positive for DNA fragmentation was increased (p < .001) in the RPL group (38 +/- 4.2) compared to the donor (11.9 +/- 1.0) or general population (22 +/- 2.0) control groups. In the RPL group, no correlation was observed between semen quality parameters and the TUNEL data. These data indicate that some RPL patients have a significant increase of sperm DNA fragmentation, which may be causative of pregnancy loss in some patients.
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Cites
Lamb, D. J. (2000) · Journal of Andrology · doi:10.1002/j.1939-4640.2000.tb03272.x · Cited by 2,077
Sun, J.-G., Jurisicova, A., & Casper, R. F. (1997) · Biology of Reproduction · doi:10.1095/biolreprod56.3.602 · Cited by 753
DNA Integrity in Human Spermatozoa: Relationships With Semen Quality
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Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients
Kodama, H., Yamaguchi, R., Fukuda, J., Kasai, H., & Tanaka, T. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00236-7 · Cited by 527
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Zini, A., Bielecki, R., Phang, D., & Zenzes, M. T. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(00)01796-9 · Cited by 451
Practical Laboratory Andrology
Mortimer, D. (1994) · doi:10.1093/oso/9780195065954.001.0001 · Cited by 415
Hughes, C. M., Lewis, S. E. M., McKelvey-Martin, V. J., & Thompson, W. (1996) · Molecular Human Reproduction · doi:10.1093/molehr/2.8.613 · Cited by 395
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Cited by
Evaluation and treatment of recurrent pregnancy loss: a committee opinion
(2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.06.048 · Cited by 1,308
Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis
Sakkas, D., & Alvarez, J. G. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2009.10.046 · Cited by 782
The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis
Robinson, L., Gallos, I. D., Conner, S. J., Rajkhowa, M., Miller, D., Lewis, S., Kirkman-Brown, J., & Coomarasamy, A. (2012) · Human Reproduction · doi:10.1093/humrep/des261 · Cited by 629
Gharagozloo, P., & Aitken, R. J. (2011) · Human Reproduction · doi:10.1093/humrep/der132 · Cited by 522
Reduction of the Incidence of Sperm DNA Fragmentation by Oral Antioxidant Treatment
Greco, E., Iacobelli, M., Rienzi, L., Ubaldi, F., Ferrero, S., & Tesarik, J. (2005) · Journal of Andrology · doi:10.2164/jandrol.04146 · Cited by 511
Metadata
- Authors
- CARRELL, D. T., LIU, L., PETERSON, C. M., JONES, K. P., HATASAKA, H. H., ERICKSON, L., & CAMPBELL, B.
- Venue
- Archives of Andrology
- Publisher
- Informa UK Limited
- Published
- 2003-01
- Volume
- 49
- Issue
- 1
- Pages
- 49-55
- ISSN
- 0148-5016 (ISSN-L)
- OpenAlex
- W2118923957
- Cited by
- 347
- References
- 22
- FWCI
- 11.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: SPERM DNA FRAGMENTATION IS INCREASED IN COUPLES WITH UNEXPLAINED RECURRENT PREGNANCY LOSS. https://app.cochat.ai/papers/10.1080/01485010290099390
- The paper
- CARRELL, D. T., LIU, L., PETERSON, C. M., JONES, K. P., HATASAKA, H. H., ERICKSON, L., & CAMPBELL, B. (2003). SPERM DNA FRAGMENTATION IS INCREASED IN COUPLES WITH UNEXPLAINED RECURRENT PREGNANCY LOSS. Archives of Andrology. https://doi.org/10.1080/01485010290099390
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
