The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders
Abstract
Reactive species play an important role in physiological functions. Overproduction of reactive species, notably reactive oxygen (ROS) and nitrogen (RNS) species along with the failure of balance by the body's antioxidant enzyme systems results in destruction of cellular structures, lipids, proteins, and genetic materials such as DNA and RNA. Moreover, the effects of reactive species on mitochondria and their metabolic processes eventually cause a rise in ROS/RNS levels, leading to oxidation of mitochondrial proteins, lipids, and DNA. Oxidative stress has been considered to be linked to the etiology of many diseases, including neurodegenerative diseases (NDDs) such as Alzheimer diseases, Amyotrophic lateral sclerosis, Friedreich's ataxia, Huntington's disease, Multiple sclerosis, and Parkinson's diseases. In addition, oxidative stress causing protein misfold may turn to other NDDs include Creutzfeldt-Jakob disease, Bovine Spongiform Encephalopathy, Kuru, Gerstmann-Straussler-Scheinker syndrome, and Fatal Familial Insomnia. An overview of the oxidative stress and mitochondrial dysfunction-linked NDDs has been summarized in this review.
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Cites
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Cited by
An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases
Teleanu, D. M., Niculescu, A.-G., Lungu, I. I., Radu, C. I., Vladâcenco, O., Roza, E., Costăchescu, B., Grumezescu, A. M., & Teleanu, R. I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23115938 · Cited by 1,085
Emerging roles of oxidative stress in brain aging and Alzheimer's disease
Ionescu-Tucker, A., & Cotman, C. W. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.07.014 · Cited by 737
Ageing, age-related diseases and oxidative stress: What to do next?
Luo, J., Mills, K., le Cessie, S., Noordam, R., & van Heemst, D. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2019.100982 · Cited by 581
“Ageing is considered to be the predominant risk factor for NDDs, and accumulative oxidative damages during ageing are the main culprits of neurological deterioration (Islam, 2017; Lin and Beal, 2006).”
BackgroundInfluentialSule, R. O., Condon, L., & Gomes, A. V. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/5563759 · Cited by 573
González-Reyes, R. E., Nava-Mesa, M. O., Vargas-Sánchez, K., Ariza-Salamanca, D., & Mora-Muñoz, L. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00427 · Cited by 527
Metadata
- Authors
- Islam, M. T.
- Venue
- Neurological Research
- Publisher
- Informa UK Limited
- Published
- 2016-11-03
- Volume
- 39
- Issue
- 1
- Pages
- 73-82
- ISSN
- 0161-6412 (ISSN-L)
- 1743-1328
- OpenAlex
- W2547689139
- Cited by
- 983
- References
- 10
- FWCI
- 23.62
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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