Cited by 343Reproductive Physiology in LivestockRuminant Nutrition and Digestive PhysiologyAnimal health and immunology

The DOI matches its Crossref record; 79 of the 80 references it cites were found in a registry or an index.

Non-esterified fatty acids (NEFA) in dairy cattle. A review

Adewuyi, A.A., Gruys, E., van Eerdenburg, F.J.C.M.·2005·Veterinary Quarterly

DOI 10.1080/01652176.2005.9695192

Open this paper in CoChat — free account

Abstract

The objective of this report is to review the literature on elevated blood concentrations of nonesterified fatty acids (NEFA) before and after parturition in high-yielding dairy cows. It highlights the factors that influence serum NEFA production and their circulation before and after parturition, such as adaptation for nutrient partitioning for fetal needs, onset of lactogenesis, stress of calving and numerous changes in physiological, metabolic, and endocrine status to accommodate parturition and lactogenesis. The role of NEFA in the liver and peripheral tissues and its toxic effects when in excess are discussed. The cow's adaptive physiologic mechanisms to prevent or decrease excessive values of serum NEFA and preventive and therapeutic interventions to enhance these mechanisms are categorized as natural and artificial antidotes respectively. Feeding systems during the dry period and daily exercise or walking activity which may burn excessive NEFA through beta-oxidation in the muscles are considered as more useful antidotes to managing the NEFA metabolism. This will minimize accumulation of lipids in the liver during early lactation and alleviate the negative effects of plasma NEFA leading to more optimal metabolic health and productivity of dairy cows.

Integrity signals

Registry

Crossref · 10.1080/01652176.2005.9695192

Cites

79 of 79 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Estimación lineal de los requerimientos nutricionales del NRC para ganado de leche.
Elizondo-Salazar, J. A. (2014) · Agronomía Mesoamericana · doi:10.15517/am.v13i1.13244 · Cited by 6,497
Biology of Dairy Cows During the Transition Period: the Final Frontier?
Drackley, J. K. (1999) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(99)75474-3 · Cited by 1,962
Partitioning of Nutrients During Pregnancy and Lactation: A Review of Mechanisms Involving Homeostasis and Homeorhesis
Bauman, D. E., & Currie, W. B. (1980) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(80)83111-0 · Cited by 1,871
A Dairy Cow Body Condition Scoring System and Its Relationship to Selected Production Characteristics
Wildman, E. E., Jones, G. M., Wagner, P. E., Boman, R. L., Troutt, H. F., & Lesch, T. N. (1982) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(82)82223-6 · Cited by 1,869
The Journal of Animal Science: 1988-1990
Owens, F. N. (1992) · Journal of Animal Science · doi:10.2527/1992.70123649x · Cited by 1,584
Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation.
Bell, A. W. (1995) · Journal of Animal Science · doi:10.2527/1995.7392804x · Cited by 1,363
N UTRITIONAL R EGULATION OF M ILK F AT S YNTHESIS
Bauman, D. E., & Griinari, J. M. (2003) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.23.011702.073408 · Cited by 1,167
Physiological Changes at Parturition and Their Relationship to Metabolic Disorders
Goff, J. P., & Horst, R. L. (1997) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(97)76055-7 · Cited by 1,152
Impact of changes in organic nutrient metabolism on feeding the transition dairy cow.
Grummer, R. R. (1995) · Journal of Animal Science · doi:10.2527/1995.7392820x · Cited by 965
Etiology of Lipid-Related Metabolic Disorders in Periparturient Dairy Cows
Grummer, R. R. (1993) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(93)77729-2 · Cited by 826

Show all 80 references

Research works printed but not linked: 23

Adewuyi, AA. 2004. “Relationship between plasma NEFA concentration and Physical activity in postpartum ruminants”. Leeuwarden, Netherlands: Van Hall Institute. Bachelor of Science Thesis,
Barker BO, 1975, Journal of Dairy Science, 58, 749
Bennink MR, 1972, Journal of Dairy Science, 55, 712
Block, E and Sanchez, W. 2000. Special nutritional needs of the transition cow. Mid‐south ruminant nutrition conference. 2000, Dallas, Texas. pp.1–15.
Bryers, DI. 1999. Controlling metabolic diseases. Tri‐state Dairy Nutrition Conference Grand. April20–211999, Wayne Center Fort Wayne, Indiana.
Douglas GN, 1998, Journal of Dairy Science, 81, 295
Drackley JK, 2000, Illinois Dairy Days
Gustafson GM, 1994, Regular exercise to tied dairy cows. Effects on productivity, health and locomotion and with attention paid to the influence of light
Herdt, TH. 1997. Gastrointestinal physiology and metabolism. Textbook of Veterinary Physiology, , 2 nd edition, Edited by: Cunningham, J.G. 263–380. WB Sanders Company. 1997
Herdt TH, 1997, Michigan Dairy Review, 2
Knapp JR, 1990, Journal of Animal Science, 68, 522
2001, Nutrient requirements of Dairy Cattle.
Nelson DL, 2005, Lehninger Principles of Biochemistry,, 600
Oldick, BS. 1999. Effect of level and source of energy during the periparturient period on reproductive performance. Tri‐state Dairy Nutrition Conference. April20–211999, Grand Wayne Center Fort Wayne, Indiana.
Overton TR, 2001, Advances in Dairy Technology, 13, 17
Roach, JO and Benyon, S. 2003. Lipid metabolism and transport. Metabolism and Nutrition, , 2 nd edition, 55–80. Mosby: Elsevier.
Serjrsen K, 1981, Nutritional Physiology and Feeding of the Cow around Parturition., 20, 325
Shearer JK, 1992, Large Dairy Herds Management, 358
Spain, JN and Scheer, WA. 2001. The 100‐day contract with the dairy cows: Thirty days prepartum to seventy days postpartum. Tri‐state Dairy Nutrition Conference. April17–182001, Grand Wayne Center Fort Wayne, Indiana.
Underwood, JP. 1998. “Effects of feeding palatability enhancer in transition cow diet on performance of Holstein dairy cows”. University of Missouri‐Columbia. Master of Science Thesis,
Van den Top AM, 1996, Journal of Dairy Science, 126, 76
Van den Top, AM. 1995. “Diet and lipid metabolism in ruminants with particular reference to fatty liver development”. The Netherlands: Utrecht University. Thesis,
Vernon RG, 1998, Research Reviews, Hannah Research Institute Yearbook, 64

Sorted by citations

Items 101–200 of 343

Technologies used at advanced dairy farms for optimizing the performance of dairy animals: A review
Singh, A. K., Bhakat, C., Ghosh, M. K., & Dutta, T. K. (2021) · Spanish Journal of Agricultural Research · doi:10.5424/sjar/2021194-17801 · Cited by 18
The Correlation between Extracellular Heat Shock Protein 70 and Lipid Metabolism in a Ruminant Model
Petrovic, M. Ž., Cincović, M., Starič, J., Djoković, R., Belić, B., Radinović, M., Majkić, M., & Ilić, Z. (2021) · Metabolites · doi:10.3390/metabo12010019 · Cited by 17
Hydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids
Kuru, M., Makav, M., Kuru, B. B., Bektaşoğlu, F., Demir, M. C., Bulut, M., & Alwazeer, D. (2024) · Research in Veterinary Science · doi:10.1016/j.rvsc.2024.105208 · Cited by 17
Influence of energy level and nicotinic acid supplementation on apoptosis of blood leukocytes of periparturient dairy cows
Bühler, S., Frahm, J., Tienken, R., Kersten, S., Meyer, U., Huber, K., & Dänicke, S. (2016) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2016.07.007 · Cited by 17
Neutrophil extracellular traps in cattle health and disease
Xie, L., Ma, Y., OPSOMER, G., Pascottini, O. B., Guan, Y., & Dong, Q. (2021) · Research in Veterinary Science · doi:10.1016/j.rvsc.2021.06.019 · Cited by 17
Reproduction and Fertility Parameters of Dairy Cows Supplemented with Omega-3 Fatty Acid-rich Canola Oil
Otto, J. (2014) · Annual Research & Review in Biology · doi:10.9734/arrb/2014/7689 · Cited by 17
Changes in lipid droplets morphometric features in mammary epithelial cells upon exposure to non-esterified free fatty acids compared with VLDL
Mesilati‐Stahy, R., & Argov-Argaman, N. (2018) · PLoS ONE · doi:10.1371/journal.pone.0209565 · Cited by 16
Relationship of cow and calf circulating lipidomes with colostrum lipid composition and metabolic status of the cow
Klopp, R. N., Ferreira, C. R., Casey, T., & Boerman, J. P. (2021) · Journal of Dairy Science · doi:10.3168/jds.2021-21008 · Cited by 16
Multi-Channel Metabolomics Analysis Identifies Novel Metabolite Biomarkers for the Early Detection of Fatty Liver Disease in Dairy Cows
Zhang, X., Liu, T., Hou, X., Hu, C., Zhang, L., Wang, S., Zhang, Q., & Shi, K. (2022) · Cells · doi:10.3390/cells11182883 · Cited by 19
Mammary gland and milk fatty acid composition of two dairy goat breeds under feed-restriction
Palma, M., Alves, S. P., Hernández-Castellano, L. E., Capote, J., Castro, N., Henríquez, A. A., Matzapetákis, M., Bessa, R. J. B., & de Almeida, A. M. (2017) · Journal of Dairy Research · doi:10.1017/s0022029917000371 · Cited by 16
Glucose and Fatty Acid Metabolism of Dairy Cows in a Total Mixed Ration or Pasture-Based System During Lactation
García-Roche, M., Cañibe, G., Casal, A., Mattiauda, D. A., Ceriani, M., Jasinsky, A., Cassina, A., Quijano, C., & Carriquiry, M. (2021) · Frontiers in Animal Science · doi:10.3389/fanim.2021.622500 · Cited by 16
Relationship between some variables of protein profile and indicators of lipomobilization in dairy cows after calving
Tóthová, C., Nagy, O., & Kovác, G. (2014) · Archives animal breeding/Archiv für Tierzucht · doi:10.7482/0003-9438-57-019 · Cited by 16
Changes in white blood pictures and some biochemical parameters of dairy cows in peripartum period and early lactation
Todorović, M. J., & Davidović, V. (2012) · AgroSpace (University of Belgrade, Faculty of Agriculture) · Cited by 16
Ketone bodies in blood of dairy cows: Prevalence and monitoring of subclinical ketosis
Krempaský, M., Maskaľová, I., Bujňák, L., & Vajda, V. (2014) · Acta Veterinaria Brno · doi:10.2754/avb201483040411 · Cited by 15
Rumen microbial composition associated with the non‐glucogenic to glucogenic short‐chain fatty acids ratio in Holstein cows
Takizawa, S., Shinkai, T., Kobayashi, Y., Masuda, M., Hashiba, K., Uchisawa, K., & Terada, F. (2023) · Animal Science Journal · doi:10.1111/asj.13829 · Cited by 15
Effects of perinatal stress on the metabolites and lipids in plasma of dairy goats
Huang, Y., Kong, Y., Li, B., Zhao, C., Loor, J. J., Tan, P., Yuan, Y., Zeng, F., Zhu, X., Qi, S., et al. (2023) · Stress Biology · doi:10.1007/s44154-023-00088-z · Cited by 15
A Tale of Two Biomarkers: Untargeted 1H NMR Metabolomic Fingerprinting of BHBA and NEFA in Early Lactation Dairy Cows
Luke, T. D. W., Pryce, J. E., Wales, W. J., & Rochfort, S. J. (2020) · Metabolites · doi:10.3390/metabo10060247 · Cited by 15
Effect of different fatty acids on the proliferation and cytokine production of dairy cow peripheral blood mononuclear cells
Vanacker, N., Blouin, R., Ster, C., & Lacasse, P. (2022) · Journal of Dairy Science · doi:10.3168/jds.2021-21296 · Cited by 15
Phenotyping metabolic status of dairy cows using clustering of time profiles of energy balance peripartum
Vossebeld, F., van Knegsel, A. T. M., & Saccenti, E. (2022) · Journal of Dairy Science · doi:10.3168/jds.2021-21518 · Cited by 15
Characterization of functional traits with focus on udder health in heifers with divergent paternally inherited haplotypes on BTA18
Heimes, A., Brodhagen, J., Weikard, R., Hammon, H. M., Meyerholz, M., Petzl, W., Zerbe, H., Engelmann, S., Schmicke, M., Hoedemaker, M., et al. (2019) · BMC Veterinary Research · doi:10.1186/s12917-019-1988-4 · Cited by 16
BEEF SPECIES SYMPOSIUM: Potential limitations of NRC in predicting energetic requirements of beef females within western U.S. grazing systems1,2
Petersen, M. K., Mueller, C. J., Mulliniks, J. T., Roberts, A. J., DelCurto, T., & Waterman, R. C. (2014) · Journal of Animal Science · doi:10.2527/jas.2013-7310 · Cited by 15
The concurrent and carry over effects of long term changes in energy intake before insemination on pregnancy per artificial insemination in heifers
Parr, M. H., Crowe, M. A., Lonergan, P., Evans, A. C. O., Fair, T., & Diskin, M. G. (2015) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2015.03.019 · Cited by 15
Metabolic adaptations associated with irreversible glucose loss are different to those observed during under-nutrition
Meier, S., Gore, P. J. S., Barnett, C. M. E., Cursons, R. T., Phipps, D., Watkins, K. A., & Verkerk, G. A. (2007) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2007.08.002 · Cited by 15
Metabolic and hormonal control of energy utilization and partitioning from early to mid lactation in Sarda ewes and Saanen goats
Lunesu, M. F., Bomboi, G., Marzano, A., Comin, A., Prandi, A., Sechi, P., Nicolussi, P., Decandia, M., Manca, C., Atzori, A. S., et al. (2021) · Journal of Dairy Science · doi:10.3168/jds.2020-19462 · Cited by 17
Peroxisome Proliferator-Activated Receptor Activation in Precision-Cut Bovine Liver Slices Reveals Novel Putative PPAR Targets in Periparturient Dairy Cows
Busato, S., Ford, H. R., Abdelatty, A. M., Estill, C. T., & Bionaz, M. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.931264 · Cited by 15
Effects of divergent Holstein-Friesian strain and diet on diurnal patterns of plasma metabolites and hormones
Meier, S., Kolver, E. S., Verkerk, G. A., & Roche, J. R. (2010) · Journal of Dairy Research · doi:10.1017/s002202991000052x · Cited by 13
Sugarcane bagasse as only roughage for crossbred lactating cows in semiarid regions
Freitas, W. R., Ferreira, M. D. A., Silva, J. L., Véras, A. S. C., de Barros, L. J. A., Alves, A. M. S. V., Chagas, J. C. C., Siqueira, T. D. Q., & de Almeida, G. A. P. (2018) · Pesquisa Agropecuária Brasileira · doi:10.1590/s0100-204x2018000300014 · Cited by 13
Physiological indicators of animal welfare
Serra, M., Wolkers, C. P. B., & Urbinati, E. C. (2018) · Revista Brasileira de Zoociências · doi:10.34019/2596-3325.2018.v19.24726 · Cited by 17
Energy balance in lactating goats: Response to mixture of conjugated linoleic acid
Granados–Rivera, L. D., Mendo, O. H., & Maldonado‐Jáquez, J. A. (2020) · Animal Science Journal · doi:10.1111/asj.13347 · Cited by 13
Analysis of the transcriptome of bovine endometrial cells isolated by laser micro-dissection (2): impacts of post-partum negative energy balance on stromal, glandular and luminal epithelial cells
Chankeaw, W., Lignier, S., Richard, C., Ntallaris, T., Raliou, M., Guo, Y., Plassard, D., Bevilacqua, C., Sandra, O., Andersson, G., et al. (2021) · BMC Genomics · doi:10.1186/s12864-021-07713-z · Cited by 13
Effect of high NEFA concentration on lipid metabolism disorders in hepatocytes based on lipidomics
Fan, X., Xu, J., Hu, Y., Wang, K., Zhao, Y., Cai, J., Zhang, X., Pan, B., Xu, A., Chen, Y., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1372296 · Cited by 12
Impact of prepartum body condition score loss on metabolic status during the transition period and subsequent fertility in Brown Swiss dairy cows
Çolakoğlu, H. E., Yazlık, M. O., Pekcan, M., Kaya, U., Kaçar, C., VURAL, M. R., Kurt, S., Yildirim, M. M., Bas, A., & Küplülü, Ş. (2019) · Journal of Veterinary Research · doi:10.2478/jvetres-2019-0039 · Cited by 12
Plasma metabolic characterisation of dairy cows with inactive ovaries and oestrus during the peak of lactation
Song, Y., Hu, P., Bai, Y., Zhao, C., Xia, C., & Xu, C. (2019) · Journal of Veterinary Research · doi:10.2478/jvetres-2019-0047 · Cited by 12
Behavior and blood profile in Friesian-Holstein dairy cows in the special region of Yogyakarta, Indonesia
Hudaya, M. F., Sitaresmi, P. I., Noviandi, C. T., Widyobroto, B. P., & Widayati, D. T. (2020) · Journal of Animal Behaviour and Biometeorology · doi:10.31893/jabb.20032 · Cited by 12
A comparative analysis of rumen pH, milk production characteristics, and blood metabolites of Holstein cattle fed different forage levels for the establishment of objective indicators of the animal welfare certification standard
Baek, D. J., Kwon, H. C., Mun, A. L., Lim, J. R., Park, S.-W., & Han, J. S. (2021) · Animal Bioscience · doi:10.5713/ab.21.0079 · Cited by 12
Influence of rumen bypass fat supplementation during early lactation in tropical crossbred dairy cattle
Ranaweera, K. K. T. N., Mahipala, M. B. P. K., & Weerasinghe, W. M. P. B. (2019) · Tropical Animal Health and Production · doi:10.1007/s11250-019-02140-5 · Cited by 12
Correction to: Characterization of functional traits with focus on udder health in heifers with divergent paternally inherited haplotypes on BTA18
Heimes, A., Brodhagen, J., Weikard, R., Hammon, H. M., Meyerholz, M., Petzl, W., Zerbe, H., Engelmann, S., Schmicke, M., Hoedemaker, M., et al. (2019) · BMC Veterinary Research · doi:10.1186/s12917-019-2034-2 · Cited by 11
UHPLC-QTOF/MS Untargeted Lipidomics and Caffeine Carry-Over in Milk of Goats under Spent Coffee Ground Enriched Diet
Casula, M., Scano, P., Manis, C., Tolle, G., Nudda, A., Carta, S., Pulina, G., & Caboni, P. (2023) · Applied Sciences · doi:10.3390/app13042477 · Cited by 11
Effects of preweaning milk allowance on long-term metabolism in Holstein heifers
Leal, L. N., Daniel, J., Doelman, J., Keppler, B. R., Steele, M. A., & Martín‐Tereso, J. (2025) · Journal of Dairy Science · doi:10.3168/jds.2024-26005 · Cited by 11
Prepartum and postpartum nutritional management to optimize fertility in beef cattle
Meteer, W., Shike, D. W. W., & Cardoso, F. C. (2015) · ACTA SCIENTIAE VETERINARIAE · Cited by 11
Ketosis Alters Transcriptional Adaptations of Subcutaneous White Adipose Tissue in Holstein Cows during the Transition Period
Ning, M., Zhao, Y., Li, Z., & Cao, J. (2022) · Animals · doi:10.3390/ani12172238 · Cited by 11
Effect of application of an external teat sealant and/or oral treatment with a monensin capsule pre-calving on the prevalence and incidence of subclinical and clinical mastitis in dairy heifers
McDougall, S., Parker, K., Weir, A., & Compton, C. (2008) · New Zealand Veterinary Journal · doi:10.1080/00480169.2008.36820 · Cited by 11
High non‐esterified fatty acid concentrations promote expression and secretion of fibroblast growth factor 21 in calf hepatocytes cultured in vitro
Wang, J., Guo, Y., Kong, Y., Dai, S., & Zhao, B. (2017) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.12699 · Cited by 10
Liver transcriptome response to periparturient hormonal and metabolic changes depends on the postpartum occurrence of subacute ruminal acidosis in Holstein cows
Tsuchiya, Y., Chiba, E., Sugino, T., Kawashima, K., Kushibiki, S., Kizaki, K., Kim, Y., & Sato, S. (2021) · Physiological Genomics · doi:10.1152/physiolgenomics.00048.2021 · Cited by 11
Non-esterified fatty acids promote expression and secretion of angiopoietin-like protein 4 in calf hepatocytes cultured in vitro
Wang, J., Zhu, X., Wang, Z., Yao, J., Zhao, B., & Liu, G. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2301-2 · Cited by 10
Effects of immunocastration performed at two live weights on the growth physiology, temperament and testicular development of feral beef bulls
Clavé, A. N., Ripoll, G., Casasús, I., & Sanz, A. (2019) · Animal Science Journal · doi:10.1111/asj.13307 · Cited by 10
The comparative effects of dietary monensin and propylene glycol on insulin resistance of transition dairy cows
Chalmeh, A., Pourjafar, M., Badiei, K., Jalali, M., & Sebdani, M. M. (2019) · Tropical Animal Health and Production · doi:10.1007/s11250-019-02160-1 · Cited by 10
Supplementation of rangeland primiparous Bos indicus x Bos taurus beef heifers during lactation. 1. Effects on dam milk production and liveweight, bull calf growth, live carcass characteristics and metabolic hormone concentrations
Callaghan, M. J., Rodgers, R. J., & Perry, V. E. A. (2020) · Theriogenology · doi:10.1016/j.theriogenology.2020.04.030 · Cited by 10
Effects of rumen-protected methionine supplementation on dairy cows during early postpartum
Michelotti, T. C., Pacheco, H. A., Leão, G. F. M., Lopes, F., Osorio, J. S., & de Almeida, R. (2021) · Journal of Applied Animal Research · doi:10.1080/09712119.2021.1942882 · Cited by 10
NEFA Promotes Autophagosome Formation through Modulating PERK Signaling Pathway in Bovine Hepatocytes
Huang, Y., Zhao, C., Liu, Y., Kong, Y., Tan, P., Liu, S., Zeng, F., Yuan, Y., Li, X., Liu, G., et al. (2021) · Animals · doi:10.3390/ani11123400 · Cited by 11
Treatment and post-treatment effects of dietary supplementation with safflower oil and linseed oil on milk components and blood metabolites of Canadian Holstein cows
Ammah, A. A., Benchaar, C., Bissonnette, N., Gévry, N. Y., & Ibeagha-Awemu, E. M. (2018) · Journal of Applied Animal Research · doi:10.1080/09712119.2017.1422256 · Cited by 9
Association between biochemical parameters and ultrasonographic measurement for the assessment of hepatic lipidosis in dairy cows
Elshafey, B. G., Elfadadny, A., Metwally, S., Saleh, A. G., Ragab, R. F., Hamada, R., Mandour, A. S., Hendawy, A. O., Alkazmi, L. M., Ogaly, H. A., et al. (2023) · Italian Journal of Animal Science · doi:10.1080/1828051x.2023.2170284 · Cited by 9
Abomasal infusion of branched-chain amino acids or branched-chain keto-acids alter lactation performance and liver triglycerides in fresh cows
Gallagher, K., Bernstein, I., Collings, C., Main, D., Ahmad, G., Naughton, S., Daddam, J. R., Mavangira, V., Vandehaar, M., & Zhou, Z. (2024) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-023-00973-7 · Cited by 9
Bile acid profiles and mRNA abundance of bile acid-related genes in adipose tissue of dairy cows with high versus normal body condition
Dicks, L., Schuh, K., Prehn, C. P., Sadri, H., Muráni, E., Ghaffari, M. H., & Häussler, S. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-24346 · Cited by 9
The association between metabolic profile indices, clinical parameters, and ultrasound measurement of backfat thickness during the periparturient period of dairy cows
Cellini, M., Hussein, H. A., Elsayed, H. K., & Sayed, A. S. (2019) · Comparative Clinical Pathology · doi:10.1007/s00580-019-02923-0 · Cited by 9
Comparative Analysis between Portable Glucometer and Enzyme Method for Measurement of Blood Glucose Levels in Cattle
Helayel, M. A., da Cunha, N. C., Moron, S. E., da Silva, P. C. A. R., da Cunha, I. M., Chenard, M. G., Xavier, M. D. S., Carvalho, V. D. A. N., Nunes, G. S., & Lopes, S. D. P. (2020) · ACTA SCIENTIAE VETERINARIAE · doi:10.22456/1679-9216.102954 · Cited by 9
Effects of boom and bust grazing management on vegetation and health of beef cattle used for wildfire prevention in a Mediterranean forest
Teruel-Coll, M., Pareja, J., Bartolomé, J., Serrano, E., Mentaberre, G. G., Cuenca, R., Espunyes, J., Pauné, F., & Calleja, J. A. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.02.037 · Cited by 13
Adipose tissue oxylipin profile changes with subclinical ketosis and depot in postpartum dairy cows
Sparks, B. B., Ford, H. R., Michelotti, T. C., & Strieder‐Barboza, C. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-25178 · Cited by 8
Persistently high concentrations of β-hydroxybutyrate affect hepatic SOD2 expression and blood SOD activity in high-yielding dairy cows
Grzybowska, D., Żarczyńska, K., Sobiech, P., Brym, P., & Tobolski, D. (2025) · BMC Veterinary Research · doi:10.1186/s12917-024-04464-3 · Cited by 8
Changes in haematological and serum biochemical parameter concentrations from the day of calving to ketosis onset in Holstein dairy cows during the postpartum period
Ha, S., Kang, S.-J., Jung, M., Kim, S. B., Hwang, S., Lee, J., Kim, D. H., Choi, K. C., & Park, J. (2025) · Irish Veterinary Journal · doi:10.1186/s13620-025-00293-4 · Cited by 8
Hermetia illucens oil vs. hydrogenated palm fat in dairy cow nutrition: effects on digestive parameters, oxidative stress, and milk production performance
Rastello, L., Gasco, L., Coppa, M., Gerbelle, M., Colombini, S., Battelli, M., Badino, P., Vernetti-Prot, L., Toral, P. G., Brugiapaglia, A., et al. (2025) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-025-01222-9 · Cited by 8
An evaluation of maternal serum dynamic thiol-disulfide homeostasis and ischemia modified albumin changes in pregnant women with COVID-19
Erol, S. A., Anuk, A. T., Tanaçan, A., Sağır, H. S., Keskin, H. L., Neşelioğlu, S., Erel, Ö., Tekın, Ö. M., & Şahın, D. (2022) · Journal of Turkish Society of Obstetric and Gynecology · doi:10.4274/tjod.galenos.2022.72929 · Cited by 8
Effect of Parity, Body Condition Score at Calving, and Milk Yield on the Metabolic Profile of Gyr Cows in the Transition Period
Breda, J. C. D. S., Filho, E. J. F., Flaiban, K. K. M. D. C., & Lisbôa, J. A. N. (2023) · Animals · doi:10.3390/ani13152509 · Cited by 8
Virtual fences are not more stressful than conventional electric fences in rotationally stocked beef cattle
Jeffus, J., Wagner, K. L., Goodman, L. E., Parker, T., Wilson, B. K., Foote, A. P., & Reuter, R. R. (2025) · Rangelands · doi:10.1016/j.rala.2024.11.002 · Cited by 8
Relationship between β-hydroxybutyrate and the fat: proteína de leche durante la lactancia temprana en vacas lecheras
García-Casillas, A. C., Montiel, R., Borderas, T. F., & Girard, V. (2015) · Archivos de medicina veterinaria · doi:10.4067/s0301-732x2015000100005 · Cited by 8
Effects of dry period length on milk yield and content and metabolic status of high-producing dairy cows under heat stress
Boustan, A., Vahedi, V., فاراب, م. ع., Karami, H., Sharifi, R. S., Evrigh, N. H., Ghazaei, C., & Salem, A. Z. M. (2021) · Tropical Animal Health and Production · doi:10.1007/s11250-021-02634-1 · Cited by 8
The effects of Zinc-Methionine on glucose metabolism and insulin resistance during late pregnancy in ewes
Sadegzadeh-Sadat, M., Anassori, E., Behroozyar, H. K., & Asri‐Rezaei, S. (2021) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2021.106647 · Cited by 8
What to feed or what not to feed-that is still the question
Lech, J. C., Dorfsman, S. I., Répás, Z., Krüger, T. P. J., Gyalai, I. M., & Boros, L. G. (2021) · Metabolomics · doi:10.1007/s11306-021-01855-7 · Cited by 8
Qualitative and Quantitative Changes in Total Lipid Concentration and Lipid Fractions in Liver Tissue of Periparturient German Holstein Dairy Cows of Two Age Groups
Theinert, K. B., Snedec, T., Pietsch, F., Theile, S., Leonhardt, A.-S., Spilke, J., Pichelmann, S., Bannert, E., Reichelt, K., Dobeleit, G., et al. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.814808 · Cited by 8
The Effect of Supplementation of Rumen-Protected Choline on Reproductive and Productive Performances of Dairy Cows
Mečionytė, I., Palubinskas, G., Anskienė, L., Japertienė, R., Juodžentytė, R., & Žilaitis, V. (2022) · Animals · doi:10.3390/ani12141807 · Cited by 8
Soybean oil and calcium salts of fatty acids as fat sources for Holstein dairy cows in transition period
Gandra, J. R., Junior, J. E. D. F., Filho, M. M., Barletta, R. V., Verdurico, L. C., & Rennó, F. P. (2014) · Revista Brasileira de Saúde e Produção Animal · doi:10.1590/s1519-99402014000100012 · Cited by 8
Performance and health of young rosé veal calves supplemented with yeast (Saccharomyces cerevisiae) and a postbiotic from Lactobacillus acidophilus
Thorsteinsson, M. M., & Vestergaard, M. (2020) · Journal of Animal and Feed Sciences · doi:10.22358/jafs/124040/2020 · Cited by 8
TNF-α level and metabolic status in α-tocopheryl acetate supplemented high body condition periparturient crossbred cows during summer and winter
Chandra, G., Aggarwal, A., Singh, A., & Singh, M. (2012) · The Indian Journal of Animal Sciences · doi:10.56093/ijans.v82i9.23653 · Cited by 8
Effects of vitamin D3 injection in close‐up period on insulin resistance and energy balance in transition dairy cows
Hassanabadi, M., Mohri, M., & Seifi, H. A. (2021) · Veterinary Medicine and Science · doi:10.1002/vms3.692 · Cited by 7
Blood serum metabolic profile and fatty acid composition in sheep fed concentrates with Camelina sativa cake and distillers dried grains with solubles
Steppa, R., Cieślak, A., Szumacher‐Strabel, M., Bielińska-Nowak, S., Bryszak, M., Stanisz, M., & Szkudelska, K. (2017) · Small Ruminant Research · doi:10.1016/j.smallrumres.2017.08.010 · Cited by 7
Association of prepartum lying time with nonesterified fatty acids and stillbirth in prepartum dairy heifers and cows
Menichetti, B. T., Piñeiro, J. M., Barragan, A. A., Relling, A. E., García-Guerra, A., & Schuenemann, G. M. (2020) · Journal of Dairy Science · doi:10.3168/jds.2020-18629 · Cited by 7
The Impact of Overstocking and Negative Energy Balance on Quantitative Measurement of Non-typhoidal Salmonella in Periparturient Dairy Cattle
Muñoz-Vargas, L., Pempek, J. A., Proudfoot, K. L., Eastridge, M. L., Rajala‐Schultz, P. J., Wittum, T. E., & Habing, G. G. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.779900 · Cited by 7
Feeding Flaxseed and Lupins during the Transition Period in Dairy Cows: Effects on Production Performance, Fertility and Biochemical Blood Indices
Nanas, I., Dokou, S., Athanasiou, L. V., Dovolou, E., Chouzouris, T. M., Vasilopoulos, S., Grigoriadou, K., Giannenas, Ι., & Amiridis, G. S. (2023) · Animals · doi:10.3390/ani13121972 · Cited by 7
Feed intake, milk yield and metabolic status of early-lactation Swedish Holstein and Swedish Red dairy cows of different parities fed grass silage and two levels of byproduct-based concentrate
Karlsson, J., Lindberg, M., Åkerlind, M., & Holtenius, K. (2020) · Livestock Science · doi:10.1016/j.livsci.2020.104304 · Cited by 7
Short communication: Free fatty acid receptors FFAR1 and FFAR2 during the peripartal period in liver of dairy cows grouped by their postpartum plasma β-hydroxybutyrate concentrations
Aguinaga, M. A., Schäff, C. T., Albrecht, E., Hammon, H. M., Kuhla, B., Röntgen, M., Nürnberg, G., & Mielenz, M. (2017) · Journal of Dairy Science · doi:10.3168/jds.2016-11021 · Cited by 7
A Forage Allowance by Forage Type Interaction Impacts the Daily Milk Yield of Early Lactation Dairy Cows
Langworthy, A. D., Freeman, M., Hills, J. L., McLaren, D. K., Rawnsley, R., & Pembleton, K. G. (2023) · Animals · doi:10.3390/ani13081406 · Cited by 6
Cow-calf relationships of endocrine and metabolic parameters immediately after parturition
Freihofer, A. L. M., Bruckmaier, R. M., & Gross, J. J. (2025) · Journal of Dairy Science · doi:10.3168/jds.2025-26462 · Cited by 7
Metabolomic analysis of rumen-protected branched-chain amino acids in primiparous dairy cows
Zhao, Z., Dong, J., Wang, D., Chen, Z., Tian, X., Meng, Y., Zou, Y., Zhao, Y., Qin, G., Wang, T., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1385896 · Cited by 6
2,4-Thiazolidinedione in Well-Fed Lactating Dairy Goats: I. Effect on Adiposity and Milk Fat Synthesis
Jaaf, S., da Rosa, F. T., Moridi, M., Osorio, J. S., Lohakare, J., Trevisi, E., Filley, S. J., Cherian, G., Estill, C. T., & Bionaz, M. (2019) · Veterinary Sciences · doi:10.3390/vetsci6020045 · Cited by 6
NETosis of Peripheral Neutrophils Isolated From Dairy Cows Fed Olive Pomace
Ciliberti, M. G., Albenzio, M., Claps, S., Santillo, A., Marino, R., & Caroprese, M. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.626314 · Cited by 6
Allostatic Load Index Effectively Measures Chronic Stress Status in Zoo-Housed Giraffes
Beer, H. N., Karr, L. K., Shrader, T. C., & Yates, D. T. (2023) · Journal of Zoological and Botanical Gardens · doi:10.3390/jzbg4030044 · Cited by 7
The effect of feeding maize silage 1 h or 9 h before the herbage meal on dry matter intake, milk production, nitrogen partitioning and rumen function of lactating dairy cows
Al-Marashdeh, O., Gregorini, P., Greenwood, S. L., & Edwards, G. R. (2015) · Animal Production Science · doi:10.1071/an14790 · Cited by 6
Evaluation of blood metabolites in dairy cows grazing under two pasture allowances and supplemented with corn silage under restricted grazing conditions
Moráles-Ramírez, Á., Grob, D., Wittwer, F., Müller, A., Balocchi, Ó., & Pulido, R. G. (2016) · Revista Brasileira de Zootecnia · doi:10.1590/s1806-92902016001100007 · Cited by 6
Investigation changes in production, some blood hormones, and metabolites, serum and colostrum IgG of calves of Holstein cows fed with two levels of zinc supplement in transitional period
Allahyari, S., Chaji, M., & Mamuie, M. (2019) · Journal of Applied Animal Research · doi:10.1080/09712119.2019.1653301 · Cited by 6
Maximizing Lucerne (Medicago sativa) Pasture Intake of Dairy Cows: 1-the Effect of Pre-Grazing Pasture Height and Mixed Ration Level
Ison, K. A. D., Benvenutti, M. A., Mayer, D. G., Quigley, S. P., & Barber, D. G. (2020) · Animals · doi:10.3390/ani10050860 · Cited by 5
Maximising Lucerne (Medicago sativa) Pasture Intake of Dairy Cows: 2—The Effect of Post-Grazing Pasture Height and Mixed Ration Level
Ison, K. A. D., Benvenutti, M. A., Mayer, D. G., Quigley, S. P., & Barber, D. G. (2020) · Animals · doi:10.3390/ani10050904 · Cited by 6
Impact of a reduced metabolizable protein supply during the transition period on the immune and metabolic status of dairy cows
Tapp, G., Lacasse, P., Beaudoin, F., Ouellet, D. R., Malouin, F., & Ster, C. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-25362 · Cited by 5
Resveratrol reverses Palmitic Acid-induced cow neutrophils apoptosis through shifting glucose metabolism into lipid metabolism via Cav-1/ CPT 1-mediated FAO enhancement
Li, Y., Zhang, Y., Deng, Q., Mao, J., Jia, Z., Tang, M., Zhang, Y., Zhao, J., Chen, J., Wang, Y., et al. (2023) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2023.106363 · Cited by 5
Distinctive Lipogenic Gene Expression Patterns in the Mammary Glands of Dairy Cows Are Associated with the Unique Fatty Acid Composition of Bovine Milk Fat
Tadmor‐Levi, R., & Argov-Argaman, N. (2025) · Foods · doi:10.3390/foods14030412 · Cited by 5
Ideal Housing Systems for Sheep to Cope with Climate Change
De, K., Kumar, D., Thirumurugan, P., Sahoo, A., & Naqvi, S. M. K. (2017) · Springer eBooks · doi:10.1007/978-981-10-4714-5_16 · Cited by 5
Clinico-biochemical, oxidative markers and trace elements changes in cows with ketosis
Ghanem, P. M. M., Fares, A., Abdel-Raof, M., & El-Attar, E. (2017) · Benha Veterinary Medical Journal · doi:10.21608/bvmj.2017.30475 · Cited by 5
Evaluating variations in metabolic profiles during the dry period related to the time of hyperketonemia onset in dairy cows
Rodriguez, Z., Picasso‐Risso, C., Gaire, T. N., Nakagawa, K., Noyes, N. R., Cramer, G., & Caixeta, L. S. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289165 · Cited by 6
Experimental hyperlipidemia induces insulin resistance in sheep
Akbari, H., Dalir‐Naghadeh, B., Asri‐Rezaei, S., Hadian, M., & Boston, R. C. (2015) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2015.06.002 · Cited by 5
Effect of crude degummed canola oil and ad libitumgrazing on plasma metabolites of primiparous Holstein-Friesian cows in a pasture-based system
Otto, J. R., Malau‐Aduli, B. S., Balogun, R. O., Nish, P., & Malau‐Aduli, A. E. O. (2014) · BMC Veterinary Research · doi:10.1186/s12917-014-0224-5 · Cited by 5
Luteal activity and effect of dietary energy restriction on follicular development in lactating cows
Comin, A., Peric, T., Montillo, M., Cappa, A., Marchi, V., Veronesi, M. C., & Prandi, A. (2017) · Reproduction in Domestic Animals · doi:10.1111/rda.12959 · Cited by 5

Authors: Adewuyi, A. A., Gruys, E., & van Eerdenburg, F. J. C. M.
Affiliations: Utrecht University (NL)
Venue: Veterinary Quarterly
Publisher: Informa UK Limited
Published: 2005-09
Volume: 27
Issue: 3
Pages: 117-126
ISSN: 0165-2176 (ISSN-L)
1875-5941
DOI: 10.1080/01652176.2005.9695192
OpenAlex: W2049628589
Cited by: 343
References: 80
Citations by year: 2026: 19 · 2025: 30 · 2024: 22 · 2023: 34 · 2022: 26 · 2021: 32 · 2020: 33 · 2019: 24 · 2018: 21 · 2017: 18 · 2016: 9 · 2015: 16 · 2014: 20 · 2013: 8 · 2012: 6
FWCI: 1.18
Type: journal article
Language: en
Open access: closed
Locations: Veterinary Quarterly (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Reproductive Physiology in Livestock
Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Ruminant Nutrition and Digestive Physiology
Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal health and immunology
Keywords: free fatty acids, dairy cattle, childbirth, lactogenesis, hepatic lipid accumulation, fatty acid beta-oxidation, dry period feeding, physical activity, endocrine changes, antidotes
MeSH terms: Adaptation, Physiological, Animals, Cattle, Fatty Acids, Nonesterified, Female, Lactation, Nutritional Requirements, Pregnancy, Parturition

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Non-esterified fatty acids (NEFA) in dairy cattle. A review

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks