The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
Magnetic hyperthermia therapy for the treatment of glioblastoma: a review of the therapy’s history, efficacy and application in humans
Open accessAbstract
Hyperthermia therapy (HT) is the exposure of a region of the body to elevated temperatures to achieve a therapeutic effect. HT anticancer properties and its potential as a cancer treatment have been studied for decades. Techniques used to achieve a localised hyperthermic effect include radiofrequency, ultrasound, microwave, laser and magnetic nanoparticles (MNPs). The use of MNPs for therapeutic hyperthermia generation is known as magnetic hyperthermia therapy (MHT) and was first attempted as a cancer therapy in 1957. However, despite more recent advancements, MHT has still not become part of the standard of care for cancer treatment. Certain challenges, such as accurate thermometry within the tumour mass and precise tumour heating, preclude its widespread application as a treatment modality for cancer. MHT is especially attractive for the treatment of glioblastoma (GBM), the most common and aggressive primary brain cancer in adults, which has no cure. In this review, the application of MHT as a therapeutic modality for GBM will be discussed. Its therapeutic efficacy, technical details, and major experimental and clinical findings will be reviewed and analysed. Finally, current limitations, areas of improvement, and future directions will be discussed in depth.
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Cites
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Heating technology for malignant tumors: a review
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Self-citationCancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies
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Self-citationMechanisms of Resistance and Current Treatment Options for Glioblastoma Multiforme (GBM)
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Glioblastoma Therapy: Past, Present and Future
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Metadata
- Authors
- Mahmoudi, K., Bouras, A., Bozec, D., Ivkov, R., & Hadjipanayis, C.
- Venue
- International Journal of Hyperthermia
- Publisher
- Informa UK Limited
- Published
- 2018-02-06
- Volume
- 34
- Issue
- 8
- Pages
- 1316-1328
- ISSN
- 0265-6736 (ISSN-L)
- 1464-5157
- OpenAlex
- W2790388651
- Cited by
- 414
- References
- 114
- FWCI
- 14.82
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Mahmoudi, K., Bouras, A., Bozec, D., Ivkov, R., & Hadjipanayis, C. (2018). Magnetic hyperthermia therapy for the treatment of glioblastoma: a review of the therapy’s history, efficacy and application in humans. International Journal of Hyperthermia. https://doi.org/10.1080/02656736.2018.1430867
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.