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Biochemical, genetic and applied aspects of drug resistance in Eimeria parasites of the fowl
Open accessAbstract
Anticoccidial drugs are widely used for the control of coccidiosis in the fowl which has inevitably led to the development of drug resistance. Resistance has developed to all of the compounds that have been introduced and if chemotherapy is to remain the principal method of control of coccidiosis, it will be important to continue the search for new anticoccidial agents. Knowledge of biochemical pathways present in the Eimeria parasite and how they differ from those of the host might help identify novel targets for inhibition. Studies of the mode of action of drugs are required if the biochemical mechanisms of resistance are to be understood. Information on the genetic origins of resistance, the stability of resistance and the factors involved in the spread of resistance throughout parasite populations is required. Since there are no methods at present to prevent resistance, more attention should be given to developing strategies for preserving the efficacy of anticoccidial drugs.
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Citations
Cited by
Williams, R. B. (2005) · Avian Pathology · doi:10.1080/03079450500112195 · Cited by 527
Coccidiosis in poultry: anticoccidial products, vaccines and other prevention strategies
Peek, H. W., & Landman, W. J. M. (2011) · Veterinary Quarterly · doi:10.1080/01652176.2011.605247 · Cited by 398
Milestones in avian coccidiosis research: A review
Chapman, H. D. (2014) · Poultry Science · doi:10.3382/ps.2013-03634 · Cited by 377
Self-citationA Selective Review of Advances in Coccidiosis Research
Chapman, H. D., Barta, J. R., Blake, D., Gruber, A., Jenkins, M., Smith, N. C., Suo, X., & Tomley, F. M. (2013) · Advances in Parasitology · doi:10.1016/b978-0-12-407705-8.00002-1 · Cited by 268
Self-citationDevelopment of immunization trials against Eimeria spp.
Ahmad, T. A., El-Sayed, B. A., & El-Sayed, L. H. (2016) · Trials in Vaccinology · doi:10.1016/j.trivac.2016.02.001 · Cited by 73
Metadata
- Authors
- Chapman, H. D.
- Venue
- Avian Pathology
- Publisher
- Informa UK Limited
- Published
- 1997-06
- Volume
- 26
- Issue
- 2
- Pages
- 221-244
- ISSN
- 0307-9457 (ISSN-L)
- 1465-3338
- OpenAlex
- W2094671950
- Cited by
- 322
- References
- 0
- FWCI
- 5.23
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Chapman, H. D. (1997). Biochemical, genetic and applied aspects of drug resistance in Eimeria parasites of the fowl. Avian Pathology. https://doi.org/10.1080/03079459708419208
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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