Cognitive and Everyday Functioning in Older and Younger Adults With and Without HIV
Open accessAbstract
The purpose of this study was to: (1) examine cognitive performance differences in older and younger adults with and without HIV, and (2) determine if such differences were related to a laboratory measure of instrumental activities of daily living (IADLs). Ninety-eight HIV-positive (69 younger, 29 older) and 103 HIV-negative (84 younger, 19 older) adults were evaluated on a number of cognitive measures. Controlling for a number of confounders, age by HIV status interactions were found on two cognitive measures, indicating poorer cognitive performance for those aging with HIV. Poorer performance on these cognitive measures corresponded with poorer performance on the Timed Instrumental Activities of Daily Living (TIADL) test. These findings suggest that as adults age with HIV, they may be at risk for cognitive declines that would impair their ability to engage in activities important for maintaining independent living.
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Self-citation
- Authors
- Vance, D. E., Wadley, V. G., Crowe, M. G., Raper, J. L., & Ball, K. K.
- Affiliations
- University of Alabama at Birmingham (US)
- Venue
- Clinical Gerontologist
- Publisher
- Informa UK Limited
- Published
- 2011-10
- Volume
- 34
- Issue
- 5
- Pages
- 413-426
- ISSN
- 0731-7115 (ISSN-L)
- 1545-2301
- PMC
- PMC3342698
- OpenAlex
- W2113937484
- Cited by
- 47
- References
- 32
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 3 · 2020: 4 · 2019: 6 · 2018: 2 · 2017: 7 · 2016: 1 · 2015: 2 · 2014: 3 · 2013: 2 · 2012: 4
- FWCI
- 1.14
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Gerontologist (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (P30AG022838)
- National Institute of Allergy and Infectious Diseases (P30AI027767)
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- HIV, aging with HIV, cognitive performance, instrumental activities of daily living, cognitive decline, independent living, older adults, young adults
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