The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Genetics of alcohol and tobacco use in humans
Open accessAbstract
The field of genetics holds great promise for furthering our understanding of the etiology of drug dependence and for identifying novel targets for treatment. Genetic studies utilizing twins and families have demonstrated a considerable role for genetics in nicotine and/or alcohol dependence. Risk for alcoholism or nicotine dependence is likely to be the result of a large number of genes, each contributing a small fraction of the overall risk. While this review will focus on studies in humans, many of the candidate genes for human nicotine and alcohol dependence listed here were originally postulated to be important, based on data from animal studies. The review will briefly summarize the results from twin and adoption studies that provide estimations of heritability, the results from chromosomal linkage studies that identify regions of chromosomes that may contain relevant genes, and the results of candidate gene studies. For each topic the data will be presented for nicotine dependence, alcohol dependence, and for nicotine and alcohol dependence together. In addition, each section will review briefly some of the confounding issues in the specific type of approach utilized.
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Cites
The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire
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Genotype Influences In Vivo Dopamine Transporter Availability in Human Striatum
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Biological Aspects of the Link between Smoking and Depression
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Cited by
Suicidal behavior and alcohol abuse.
Pompili, M., Serafini, G., Innamorati, M., Dominici, G., Ferracuti, S., Kotzalidis, G. D., Serra, G., Girardi, P., Janiri, L., Tatarelli, R., et al. (2010) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph7041392 · Cited by 477
A genome-wide association study of alcohol dependence
Bierut, L. J., Agrawal, A., Bucholz, K. K., Doheny, K. F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911109107 · Cited by 457
Kerkel, K., Spadola, A., Yuan, E., Kosek, J., Jiang, L., Hod, E., Li, K., Murty, V. V., Schupf, N., Vilain, E., et al. (2008) · Nature Genetics · doi:10.1038/ng.174 · Cited by 441
Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use
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Self-citation
Metadata
- Authors
- Tyndale, R. F.
- Venue
- Annals of Medicine
- Publisher
- Informa UK Limited
- Published
- 2003-01
- Volume
- 35
- Issue
- 2
- Pages
- 94-121
- ISSN
- 0785-3890 (ISSN-L)
- 1365-2060
- OpenAlex
- W1997942208
- Cited by
- 217
- References
- 12
- FWCI
- 12.06
- Type
- journal article
- Language
- en
- Open access
- bronze
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