Psychiatric diagnosis in primary care patients with increased depressive symptoms
Abstract
BACKGROUND: Screening of depression has been recommended in primary care and Beck's 21-item Depression Inventory (BDI-21) is a commonly used tool for screening. Depression has been shown to be frequently accompanied by comorbidities. AIMS: This study aimed to analyze the characteristics, psychiatric diagnoses, and psychiatric comorbidity of primary care patients who have been screened for depression and referred to a depression nurse. METHODS: The study subjects were primary care patients aged ≥ 35 years with depressive symptoms (BDI-21 > 9). Their psychiatric diagnosis were based on a diagnostic interview (Mini-International Neuropsychiatric Interview; M.I.N.I.) conducted by a trained study nurse. RESULTS: Of the 705 study subjects, 617 (87.5%) had at least one and 66.1% had at least two psychiatric diagnoses. The most common diagnosis was depression (63.4%). The next most common diagnoses were generalized anxiety disorder (GAD) (48.1%) and panic disorder (22.8%). Only 8.8% of the study subjects had depression without other psychiatric disorders. Ten percent of the subjects had both depression and a generalized anxiety disorder (GAD). Also other psychiatric comorbidities were common. Age was inversely associated with the psychiatric diagnosis in the M.I.N.I. CONCLUSIONS: This study suggests that most of the primary care patients with increased depressive symptoms have a psychiatric disorder. Although depression is the most common diagnosis, there are several other concurrent psychiatric comorbidities. Therefore, diagnostic assessment of primary care patients with a screening score over 9 in the BDI-21 should be reconsidered.
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Among individuals who seek treatment, depression is often an intermittent recurrent disorder over the life course, commonly with partial remission between episodes.
“Among individuals who seek treatment, depression is often an intermittent recurrent disorder over the life course, 143 commonly with partial remission between episodes. 144”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [143]
Cites
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391 · see citing works
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139 · see citing works
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961 · see citing works
Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation
Beck, A. T., Steer, R. A., & Carbin, M. G. (1988) · Clinical Psychology Review · doi:10.1016/0272-7358(88)90050-5 · Cited by 11,696 · see citing works
Vos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., Aboyans, V., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61729-2 · Cited by 8,291 · see citing works
Lecrubier, Y., Sheehan, D., Weiller, E., Amorim, P., Bonora, I., Sheehan, K. H., Janavs, J., & Dunbar, G. (1997) · European Psychiatry · doi:10.1016/s0924-9338(97)83296-8 · Cited by 3,513 · see citing works
The functioning and well-being of depressed patients. Results from the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.262.7.914 · Cited by 2,826 · see citing works
The Functioning and Well-being of Depressed Patients: Results From the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.1989.03430070062031 · Cited by 2,130 · see citing works
Assessment of Depression: The Depression Inventory
Beck, A. T., & Beamesderfer, A. (2015) · Modern problems of pharmacopsychiatry/Modern trends in pharmacopsychiatry · doi:10.1159/000395074 · Cited by 1,834 · see citing works
Screening for Depression in Adults: US Preventive Services Task Force Recommendation Statement
Siu, A. L., and the US Preventive Services Task Force (USPSTF), Bibbins-Domingo, K., Grossman, D. C., Baumann, L. C., Davidson, K. W., Ebell, M., García, F. A. R., Gillman, M., Herzstein, J., et al. (2016) · JAMA · doi:10.1001/jama.2015.18392 · Cited by 1,407 · see citing works
Bruce, S. E., Yonkers, K. A., Otto, M. W., Eisen, J. L., Weisberg, R. B., Pagano, M., Shea, M. T., & Keller, M. B. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.6.1179 · Cited by 963 · see citing works
Kessler, R. C. (2012) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2011.11.005 · Cited by 871 · see citing works
Diagnosis and Management of the Metabolic Syndrome
Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169405 · Cited by 803 · see citing works
Screening for Depression: Recommendations and Rationale
U.S. Preventive Services Task Force* (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-10-200205210-00012 · Cited by 524 · see citing works
Alonso, J., Petukhova, M., Vilagut, G., Chatterji, S., Heeringa, S., Üstün, T. B., Alhamzawi, A. O., Viana, M. C., Angermeyer, M., Bromet, E., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.101 · Cited by 482 · see citing works
Screening and case-finding instruments for depression: a meta-analysis
Gilbody, S., Sheldon, T., & House, A. (2008) · Canadian Medical Association Journal · doi:10.1503/cmaj.070281 · Cited by 443 · see citing works
Anxiety disorders in major depression.
Fava, M., Rankin, M. A., Wright, E. C., Alpert, J., Nierenberg, A., Pava, J. A., & Rosenbaum, J. (2000) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(00)90140-8 · Cited by 347 · see citing works
Melartin, T. K., Rytsala, H. J., Leskela, U. S., Lestela-Mielonen, P. S., Sokero, T. P., & Isometsa, E. T. (2002) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v63n0207 · Cited by 260 · see citing works
Recommendations on screening for depression in adults
Canadian Task Force on Preventive Health Care, Joffres, M., Jaramillo, A., Dickinson, J. A., Lewin, G., Pottie, K. C., Shaw, E. A., Gorber, S. C., & Tonelli, M. A. (2013) · Canadian Medical Association Journal · doi:10.1503/cmaj.130403 · Cited by 248 · see citing works
Which instruments to support diagnosis of depression have sufficient accuracy? A systematic review
Pettersson, A., Boström, K. B., Gustavsson, P., & Ekselius, L. (2015) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2015.1008568 · Cited by 187 · see citing works
Pettersson, A., Modin, S., Wahlström, R., Hammarberg, S. A. W., & Krakau, I. (2018) · BMC Family Practice · doi:10.1186/s12875-017-0674-5 · Cited by 151 · see citing works
Predictors of First Lifetime Onset of Major Depressive Disorder in Young Adulthood
Klein, D., Glenn, C. R., Kosty, D. B., Seeley, J., Rohde, P., & Lewinsohn, P. (2012) · Journal of Abnormal Psychology · doi:10.1037/a0029567 · Cited by 126 · see citing works
Viinamäki, H. T., Tanskanen, A. J., Honkalampi, K. M., Koivumaa-Honkanen, H. T., Haatainen, K. M., Kaustio, O., & Hintikka, J. (2004) · Nordic Journal of Psychiatry · doi:10.1080/08039480310000798 · Cited by 109 · see citing works
Markkula, N., Suvisaari, J., Saarni, S. I., Pirkola, S. P., Peña, S., Saarni, S. E., Ahola, K., Mattila, A. K., Viertiö, S., Strehle, J., et al. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.10.015 · Cited by 107 · see citing works
Depressive disorders in primary care: recurrent, chronic, and co-morbid
Vuorilehto, M. S., Melartin, T. K., & Isometsä, E. T. (2004) · Psychological Medicine · doi:10.1017/s0033291704003770 · Cited by 105 · see citing works
Munk-Jørgensen, P., Allgulander, C., Dahl, A. A., Foldager, L., Holm, M., Rasmussen, I., Virta, A., Huuhtanen, M.-T., & Wittchen, H.-U. (2006) · Psychiatric Services · doi:10.1176/ps.2006.57.12.1738 · Cited by 96 · see citing works
Role of common mental and physical disorders in partial disability around the world
Bruffaerts, R., Vilagut, G., Demyttenaere, K., Alonso, J., AlHamzawi, A., Andrade, L. H., Benjet, C., Bromet, E., Bunting, B., de Girolamo, G., et al. (2012) · British Journal of Psychiatry · doi:10.1192/bjp.bp.111.097519 · Cited by 96 · see citing works
Mental health and well-being in a 6-year follow-up of patients with depression
Koivumaa-Honkanen, H. T., Tuovinen, T. K., Honkalampi, K. M., Antikainen, R., Hintikka, J. J., Haatainen, K. M., & Viinamäki, H. T. (2008) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-008-0353-x · Cited by 54 · see citing works
Salokangas, R. K. R., Poutanen, O., Stengård, E., Jähi, R., & Palo‐oja, T. (1996) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1996.tb10673.x · Cited by 49 · see citing works
Nuevo, R., Lehtinen, V., Reyna-Liberato, P. M., & Ayuso‐Mateos, J. L. (2008) · Scandinavian Journal of Public Health · doi:10.1177/1403494808097169 · Cited by 49 · see citing works
The incidence of major depression in Canada: The National Population Health Survey
Wang, J., Williams, J. V. A., Lavorato, D. H., Schmitz, N., Dewa, C. S., & Patten, S. B. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.07.016 · Cited by 47 · see citing works
Rudd, M. D., & Rajab, M. H. (1995) · Cognitive Therapy and Research · doi:10.1007/bf02229676 · Cited by 31 · see citing works
Kasteenpohja, T., Marttunen, M., Aalto-Setälä, T., Perälä, J., Saarni, S. I., & Suvisaari, J. (2018) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2017.1418429 · Cited by 26 · see citing works
Lotfi, L., Flyckt, L., Krakau, I., Mårtensson, B., & Nilsson, G. H. (2010) · Nordic Journal of Psychiatry · doi:10.3109/08039481003786378 · Cited by 25 · see citing works
Markkula, N., Marola, N., Nieminen, T., Koskinen, S. V. P., Saarni, S. I., Härkänen, T., & Suvisaari, J. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.08.051 · Cited by 25 · see citing works
Stegenga, B. T., Geerlings, M. I., Torres‐González, F., Xavier, M., Švab, I., Penninx, B. W. J. H., Nazareth, I., & King, M. (2012) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-012-0626-2 · Cited by 20 · see citing works
Auvinen, P., Mäntyselkä, P. T., Koponen, H., Kautiainen, H., Korniloff, K., Ahonen, T., & Vanhala, M. J. (2017) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2017.1385849 · Cited by 15 · see citing works
Self-citationCardiometabolic risk factors in patients referred to depression nurse case managers
Koponen, H., Kautiainen, H., Leppänen, E., Mäntyselkä, P. T., & Vanhala, M. J. (2014) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2014.972451 · Cited by 13 · see citing works
Self-citationMarkkula, N., Suvisaari, J., Saarni, S. I., Pirkola, S. P., Peña, S., Saarni, S. E., Ahola, K., Mattila, A. K., Viertiö, S., Strehle, J., et al. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.11.007 · Cited by 9 · see citing works
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Time for united action on depression: a Lancet–World Psychiatric Association Commission
Herrman, H., Patel, V., Kieling, C., Berk, M., Buchweitz, C., Cuijpers, P., Furukawa, T. A., Kessler, R. C., Kohrt, B. A., Maj, M., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(21)02141-3 · Cited by 1,104 · see citing works
Cuijpers, P. J., Miguel, C., Čihařová, M., Quero, S., Plessen, C. Y., Ebert, D. D., Harrer, M., van Straten, A., & Karyotaki, E. (2023) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2023.2166578 · Cited by 30 · see citing works
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Rodríguez-Ruiz, J. G., Galvan-Tejada, C. E., Vázquez-Reyes, S., Galván-Tejada, J. I., & Gamboa-Rosales, H. (2019) · International Conference in Software Engineering Research and Innovation (CONISOFT) · doi:10.1109/conisoft.2019.00037 · Cited by 9 · see citing works
Gyllensten, A. L., Ovesson, M. N., Hedlund, L., Ambrus, L., & Tornberg, Å. B. (2019) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2019.1669706 · Cited by 9 · see citing works
Rancāns, E., Vrubļevska, J., Ķīvīte‐Urtāne, A., Ivanovs, R., & Ziedonis, D. M. (2019) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2019.1668961 · Cited by 9 · see citing works
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- Authors
- Kotiaho, S., Korniloff, K., Vanhala, M., Kautiainen, H., Koponen, H., Ahonen, T., & Mäntyselkä, P.
- Affiliations
- University of Eastern Finland (FI)
- JAMK University of Applied Sciences (FI)
- Kuopio University Hospital (FI)
- Folkhälsans Forskningscentrum (FI)
- University of Helsinki (FI)
- Corresponding author
- Kotiaho, Satu
- ORCID
- Venue
- Nordic Journal of Psychiatry
- Publisher
- Informa UK Limited
- Published
- 2019-03-30
- Volume
- 73
- Issue
- 3
- Pages
- 195-199
- ISSN
- 0029-1455 (ISSN-L)
- 0803-9488
- 1502-4725
- OpenAlex
- W2929122033
- Cited by
- 8
- References
- 39
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 2 · 2020: 1 · 2019: 3
- FWCI
- 1.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nordic Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Central Finland Health Care District
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- depression, psychiatric comorbidity, primary care, depression screening, Beck Depression Inventory, generalized anxiety disorder, panic disorder, psychiatric diagnosis
- MeSH terms
- Adult, Aged, Mental Disorders, Depressive Disorder, Female, Finland, Humans, Male, Middle Aged, Primary Health Care, Psychiatric Status Rating Scales, Comorbidity
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