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A preliminary investigation on the relationship between gut microbiota and gene expressions in peripheral mononuclear cells of infants with autism spectrum disorders
Open accessAbstract
Fecal and blood samples of infants with autism spectrum disorders (ASD) and healthy infants were analyzed to investigate the association of altered gut microbiota and ASD development. 16S rRNA gene-based sequencing found that, unlike those of healthy infants, feces of ASD infants had significantly higher and lower abundance of genera Faecalibacterium and Blautia, respectively. Moreover, DNA microarray analysis of peripheral blood mononuclear cells (PBMC) detected more highly than low expressed genes in ASD infants than in healthy infants. Gene Ontology analysis revealed that differentially expressed genes between ASD and healthy infants were involved in interferon (IFN)-γ and type-I IFN signaling pathways. Finally, strong positive correlations between expression of IFN signaling-associated genes in PBMC and fecal abundance of Faecalibacterium were found. Our results strongly suggested that altered gut microbiota in infants resulted from ASD development and was associated with systemic immunity dysregulation, especially chronic inflammation.
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QIIME allows analysis of high-throughput community sequencing data
Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887
Search and clustering orders of magnitude faster than BLAST
Edgar, R. C. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq461 · Cited by 21,098
Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy
Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 20,145
FLASH: fast length adjustment of short reads to improve genome assemblies
Magoč, T., & Salzberg, S. L. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr507 · Cited by 15,366
UCHIME improves sensitivity and speed of chimera detection
Edgar, R. C., Haas, B. J., Clemente, J. C., Quince, C., & Knight, R. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr381 · Cited by 15,114
Mechanisms of type-I- and type-II-interferon-mediated signalling
Platanias, L. C. (2005) · Nature reviews. Immunology · doi:10.1038/nri1604 · Cited by 3,631
Hsiao, E. Y., McBride, S. W., Hsien, S., Sharon, G., Hyde, E. R., McCue, T., Codelli, J. A., Chow, J., Reisman, S. E., Petrosino, J. F., et al. (2013) · Cell · doi:10.1016/j.cell.2013.11.024 · Cited by 3,283
Human nutrition, the gut microbiome and the immune system
Kau, A. L., Ahern, P. P., Griffin, N. W., Goodman, A. L., & Gordon, J. I. (2011) · Nature · doi:10.1038/nature10213 · Cited by 2,588
Lai, M.-C., Lombardo, M. V., & Baron-Cohen, S. (2014) · The Lancet · doi:10.1016/s0140-6736(13)61539-1 · Cited by 2,371
Neuroglial activation and neuroinflammation in the brain of patients with autism
Vargas, D. L., Nascimbene, C., Krishnan, C., Zimmerman, A. W., & Pardo, C. A. (2005) · Annals of Neurology · doi:10.1002/ana.20315 · Cited by 2,149
Research works printed but not linked: 2
- Kamio, 2006, Reliability and validity of the pervasive developmental disorder (PDD)-Autism society Japan rating scale (PARS): a behavior checklist for adolescents and adults with PDDs, Clin. Psychiat. (Seishin-Igaku), 48, 495
- Hill, 1981, Phase 1 human leukocyte interferon trials in cancer and leukemia, J. Clin. Hematol. Oncol, 11, 23
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Wan, Y., Zuo, T., Xu, Z., Zhang, F., Zhan, H., Dorothy, C. H. A. N., Leung, T.-F., Yeoh, Y. K., Chan, F. K. L., Chan, R., et al. (2021) · Gut · doi:10.1136/gutjnl-2020-324015 · Cited by 154
Spichak, S., Bastiaanssen, T. F. S., Berding, K., Vlckova, K., Clarke, G., Dinan, T. G., & Cryan, J. F. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.044 · Cited by 127
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Xu, R., Zhang, Y., Chen, S., Zeng, Y., Fu, X., Chen, T., Luo, S., & Zhang, X. (2022) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2022.2044286 · Cited by 96
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Lasheras, I., Seral, P., Latorre, E., Barroso, E., Gracia‐García, P., & Santabárbara, J. (2019) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2019.101874 · Cited by 66
Lee, Y., Park, J. Y., Lee, E. H., Yang, J., Jeong, B.-R., Kim, Y., Seoh, J., Lee, S., Han, P., & Kim, E. (2017) · Experimental Neurobiology · doi:10.5607/en.2017.26.5.307 · Cited by 67
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Cupertino, M. D. C., Resende, M. B., Veloso, I. D. F., de Carvalho, C. A., Duarte, V. F., & Ramos, G. A. (2019) · ABCS Health Sciences · doi:10.7322/abcshs.v44i2.1167 · Cited by 22
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Wei, Y., Shen, D., Ramzan, M. N., Emmanuel, A., Zhu, J., Yang, W., Wang, Y., & Zheng, Z. (2024) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2024.105792 · Cited by 11
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Self-citation
Metadata
- Authors
- Inoue, R., Sakaue, Y., Sawai, C., Sawai, T., Ozeki, M., Romero-Pérez, G. A., & Tsukahara, T.
- Affiliations
- Laboratory of Animal Science, Department of Agricultural and Life Sciences, Kyoto Prefectural University, Kyoto, Japan
- Shiga University of Medical Science (JP)
- Mukogawa Women's University (JP)
- Kyoto Institute of Nutrition and Pathology, Kyoto, Japan
- Kyoto Prefectural University (JP)
- ORCID
- Tsukahara, Takamitsu
- Venue
- Bioscience, Biotechnology, and Biochemistry
- Publisher
- Informa UK Limited
- Published
- 2016-12-01
- Volume
- 80
- Issue
- 12
- Pages
- 2450-2458
- ISSN
- 0916-8451 (ISSN-L)
- 1347-6947
- OpenAlex
- W2516846297
- Cited by
- 148
- References
- 69
- Citations by year
- 2026: 9 · 2025: 12 · 2024: 23 · 2023: 25 · 2022: 11 · 2021: 26 · 2020: 14 · 2019: 13 · 2018: 7 · 2017: 7 · 2016: 1
- FWCI
- 4.85
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Bioscience Biotechnology and Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- The Morinaga Foundation for Health & Nutrition
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, gut microbiota, infants, peripheral blood mononuclear cells, gene expression, Faecalibacterium, Blautia, interferon-gamma signaling, type I interferon signaling, chronic inflammation, fecal microbiota
- MeSH terms
- Autism Spectrum Disorder, Gastrointestinal Microbiome, Child, Preschool, Feces, Humans, Infant, Leukocytes, Mononuclear, Case-Control Studies, Transcriptome
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