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Direct and indirect effects of perceived social support on health-related quality of life in persons living with HIV/AIDS
Abstract
Research has established a link between perceived social support and health-related quality of life (HRQOL) among persons living with HIV/AIDS. However, little is known about the ways through which social support influences HRQOL. This study examined the direct and indirect effects of perceived social support on physical and mental HRQOL in a sample of 602 adults living with HIV in Ontario, Canada. Participants completed the Medical Outcomes Study-HIV (MOS-HIV) health survey, the MOS-HIV Social Support Scale (MOS-HIV-SSS), and the Center for Epidemiological Studies Depression-Revised scale. Data on demographic and clinical characteristics were also collected. The direct and indirect effects of social support on the two MOS-HIV HRQOL summary measures, that is, physical health summary (PHS) and mental health summary (MHS), were estimated in multiple linear regression analyses. Perceived social support had significant direct effects on PHS (B=0.04, p<0.01) and MHS (B=0.05, p<0.01). It also had significant indirect effect on both PHS (B=0.04, p<0.01) and MHS (B=0.11, p<0.01), mediated by depressive symptoms. Interventions that enhance social support have the potential to contribute to better HRQOL either directly or indirectly by decreasing the deleterious effect of depressive symptoms on HRQOL.
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“Previous studies have found a strong positive relationship between social interaction and mental health (Dour et al., 2014;Bekele et al., 2015).”
From The relationship between physical and mental health: A mediation analysis (2017) · cites this paper as Bekele et al., 2015
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Flagged first, then by citations
1 of the 52 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
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- Wu, A.W., 1999. MOS-HIV health survey users manual. Baltimore: John Hopkins University; 1999, Retrieved from http://149.142.76.35/assessment/pdf/assessments/MOS-HIV%20Users%20Manual%20%20Draft.pdf.
Cited by
Sorted by citations
The relationship between physical and mental health: A mediation analysis
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Aidala, A. A., Wilson, M. G., Shubert, V., Gogolishvili, D., Globerman, J., Rueda, S., Bozack, A. K., Cabán, M., & Rourke, S. B. (2015) · American Journal of Public Health · doi:10.2105/ajph.2015.302905 · Cited by 453
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Armoon, B., Fleury, M., Bayat, A., Fakhri, Y., Higgs, P., Moghaddam, L. F., & Gonabadi-Nezhad, L. (2022) · International Journal of Mental Health Systems · doi:10.1186/s13033-022-00527-w · Cited by 184
“The benefits include less depression [22], positive health behaviors such as adherence to treatments [23], improved quality of life [24], and slower disease progression [25].”
BackgroundZhou, K., Li, H., Wei, X., Yin, J., Liang, P., Zhang, H., Kou, L., Hao, M., You, L., Li, X., et al. (2015) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2015.03.007 · Cited by 120
“Published studies have documented that social support has a buffering effect on stressful life events and depression [12,13] as well as great impacts on treatment outcomes [14–17], especially the perceived social support [18–20].”
Background
Metadata
- Authors
- Bekele, T., Rourke, S. B., Tucker, R., Greene, S., Sobota, M., Koornstra, J., Monette, L., Rueda, S., Bacon, J., Watson, J., Hwang, S. W., Dunn, J., Guenter, D., & The Positive Spaces Healthy Places Team
- Affiliations
- Ontario HIV Treatment Network (CA)
- St. Michael's Hospital (CA)
- Positive Health Network (CA)
- Fife House (CA)
- AIDS Thunder Bay, Thunder Bay, Canada
- Bruce House, Ottawa, Canada
- Ontario Aboriginal HIV/AIDS Strategy, Toronto, Canada
- McMaster University (CA)
- Corresponding author
- Rourke, Sean B.
- ORCID
- Venue
- AIDS Care
- Publisher
- Informa UK Limited
- Published
- 2012-07-09
- Volume
- 25
- Issue
- 3
- Pages
- 337-346
- ISSN
- 0954-0121 (ISSN-L)
- 1360-0451
- OpenAlex
- W2064343532
- Cited by
- 146
- References
- 52
- Citations by year
- 2026: 2 · 2025: 11 · 2024: 8 · 2023: 7 · 2022: 10 · 2021: 11 · 2020: 13 · 2019: 13 · 2018: 17 · 2017: 10 · 2016: 14 · 2015: 16 · 2014: 9 · 2013: 4 · 2012: 1
- FWCI
- 6.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- AIDS Care (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ontario Ministry of Health and Long-Term Care
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Social Sciences › Health › Health disparities and outcomes
- Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
- Keywords
- perceived social support, health-related quality of life, HIV/AIDS, people living with HIV, depressive symptoms, mediation, physical health, mental health, MOS-HIV
- MeSH terms
- Acquired Immunodeficiency Syndrome, Adult, Aged, Depression, Female, Health Status, Humans, Male, Middle Aged, Ontario, Quality of Life, Social Support, HIV Infections, Outcome Assessment, Health Care, HIV Long-Term Survivors, Young Adult
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