Cited by 20Shoulder Injury and TreatmentMyofascial pain diagnosis and treatmentConnective tissue disorders research

Home-based exercise therapy for treating shoulder instability in patients with hypermobile Ehlers-Danlos syndrome/hypermobility spectrum disorders. A randomized trial

Spanhove, Valentien, De Wandele, Inge, Malfait, Fransiska, Calders, Patrick, Cools, Ann·2023·Disability and Rehabilitation

Abstract

Purpose To investigate the effectiveness of two home-based exercise programs for treating multidirectional shoulder instability (MDI) in patients diagnosed with Hypermobile Ehlers-Danlos syndrome (hEDS) or Hypermobility Spectrum Disorders (HSD).Methods Twenty-one hEDS/HSD patients with MDI were recruited from the Center for Medical Genetics of the Ghent University Hospital. Patients were randomly assigned to either the experimental or the control group. Both groups received a 6-month home-based exercise program. The primary outcome measure was the Western Ontario Shoulder Index (WOSI). Secondary outcomes included the Disabilities of the Arm, Shoulder and Hand (DASH), Tampa Scale for Kinesiophobia (TSK), Patient-Specific Functional Scale (PSFS), Global Rating of Change (GROC), and pain pressure thresholds. Outcomes were assessed at baseline, after 6 weeks, 12 weeks, and 24 weeks.Results Significant main effects for time were observed for all questionnaires, except for the TSK (p = 0.12). Patients improved 240 and 325 points on the WOSI after 12 (p = 0.02) and 24 weeks (p = 0.001), respectively. Additionally, patients improved 8.6 points on the DASH (p = 0.002), 4.3 points on the PSFS (p = 0.01), and 1.02 points on the GROC (p = 0.001) after 24 weeks.Conclusion No significant differences were found between group A and B. Both home-based exercise programs led to significant improvements in shoulder function. IMPLICATIONS FOR REHABILITATIONHome-based exercise therapy may be effective for treating MDI in the hEDS/HSD population.Home-based training is beneficial for improving shoulder function, but a multidisciplinary, supervised approach might be more effective for altering kinesiophobia in this patient population.

Integrity signals

Registry

Crossref · 10.1080/09638288.2022.2076932

Cites

48 of 48 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • A randomized trial of 21 patients with multidirectional shoulder instability in HSD/hEDS found home-based exercise programs were beneficial for improving shoulder function using several validated indices.

    “A randomized trial of 21 patients assessing multidirectional shoulder instability in HSD/hEDS patients found home-based exercise programs were beneficial for improving shoulder function using several different validated indices.[62]”

    From Hypermobility spectrum disorders: A review (2023) · cites this paper as [62]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Spanhove, V., De Wandele, I., Malfait, F., Calders, P., & Cools, A.
Affiliations
  • Ghent University (BE)
  • Department of Rehabilitation Sciences, Ghent University, Ghent, Belgium
  • Ghent University Hospital (BE)
Corresponding author
Spanhove, Valentien
Venue
Disability and Rehabilitation
Published
2022-05-24
Volume
45
Issue
11
Pages
1811-1821
ISSN
  • 0963-8288 (ISSN-L)
  • 1464-5165
OpenAlex
W4281381462
Cited by
20
References
48
Citations by year
2026: 7 · 2025: 3 · 2024: 2 · 2023: 7 · 2022: 1
FWCI
3.10
Type
journal article
Language
en
Open access
closed
Locations
  • Disability and Rehabilitation (publishedVersion)
  • PubMed (publishedVersion)
  • Ghent University Academic Bibliography (Ghent University) (publishedVersion)
  • Ghent University Academic Bibliography (Ghent University) (submittedVersion)
Funders
  • Research Foundation Flanders
  • The Special Research Fund of Ghent University (BOF17/DOC/220)
Topics
  • Health Sciences › Medicine › Surgery › Shoulder Injury and Treatment
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Myofascial pain diagnosis and treatment
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
Keywords
home-based exercise therapy, multidirectional shoulder instability, hypermobile Ehlers-Danlos syndrome, hypermobility spectrum disorders, shoulder function, kinesiophobia, pressure pain threshold, DASH, Patient-Specific Functional Scale
MeSH terms
Blindness, Ehlers-Danlos Syndrome, Exercise Therapy, Humans, Joint Instability, Shoulder, Shoulder Joint

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review