The effects of knee joint kinematics on anterior cruciate ligament injury and articular cartilage damage
Abstract
This study determined which knee joint motions lead to anterior cruciate ligament (ACL) rupture with the knee at 25° of flexion. The knee was subjected to internal and external rotations, as well as varus and valgus motions. A failure locus representing the relationship between these motions and ACL rupture was established using finite element simulations. This study also considered possible concomitant injuries to the tibial articular cartilage prior to ACL injury. The posterolateral bundle of the ACL demonstrated higher rupture susceptibility than the anteromedial bundle. The average varus angular displacement required for ACL failure was 46.6% lower compared to the average valgus angular displacement. Femoral external rotation decreased the frontal plane angle required for ACL failure by 27.5% compared to internal rotation. Tibial articular cartilage damage initiated prior to ACL failure in all valgus simulations. The results from this investigation agreed well with other experimental and analytical investigations. This study provides a greater understanding of the various knee joint motion combinations leading to ACL injury and articular cartilage damage.
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Previously, researchers have used displacement controlled finite element analysis to study the biomechanics of ACL during knee flexion.
“Previously, researchers have used displacement controlled finite element analysis to study the biomechanics of ACL during knee flexion [15, 17, 20].”
A mesh sensitivity analysis was performed, and the optimum mesh size of grafts was between 0.9 and 1.1 mm.
“In order to achieve balance between the accuracy of stress and the computational time, a mesh sensitivity analysis was performed by stepwise upsizing the mesh size, according to a previous study [17]. The convergence tolerance was set as a variation of stress within 5% from the previous model with higher mesh density. As a result, the optimum mesh size of grafts was between 0.9 and 1.1 mm.”
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Orsi, A. D., Canavan, P. K., Vaziri, A., Goebel, R., Kapasi, O. A., & Nayeb-Hashemi, H. (2017) · The Knee · doi:10.1016/j.knee.2017.02.010 · Cited by 41 · see citing works
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“In order to achieve balance between the accuracy of stress and the computational time, a mesh sensitivity analysis was performed by stepwise upsizing the mesh size, according to a previous study [17].”
BackgroundMethodXiao, Y., Liang, Z., Shen, S., Liu, F., Hu, H., & Chen, B. (2023) · Journal of Experimental Orthopaedics · doi:10.1186/s40634-023-00677-x · Cited by 10 · see citing works
Otani, T., Kobayashi, Y., & Tanaka, M. (2020) · Medical Engineering & Physics · doi:10.1016/j.medengphy.2020.07.015 · Cited by 7 · see citing works
- Authors
- Orsi, A. D., Chakravarthy, S., Canavan, P. K., Peña, E., Goebel, R., Vaziri, A., & Nayeb-Hashemi, H.
- Affiliations
- Northeastern University (US)
- Universidad de Zaragoza (ES)
- Qatar University (QA)
- Venue
- Computer Methods in Biomechanics and Biomedical Engineering
- Publisher
- Informa UK Limited
- Published
- 2015-06-11
- Volume
- 19
- Issue
- 5
- Pages
- 493-506
- ISSN
- 1025-5842 (ISSN-L)
- 1476-8259
- OpenAlex
- W2281653111
- Cited by
- 24
- References
- 70
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 5 · 2020: 6 · 2019: 1 · 2018: 2 · 2017: 1 · 2015: 1
- FWCI
- 1.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Computer Methods in Biomechanics & Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Qatar University QSpace (Qatar University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Knee injuries and reconstruction techniques
- Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
- Keywords
- anterior cruciate ligament injury, knee kinematics, articular cartilage damage, valgus loading, femoral external rotation, tibial internal rotation, posterolateral bundle, anteromedial bundle, failure locus, knee biomechanics
- MeSH terms
- Anterior Cruciate Ligament Injuries, Adult, Biomechanical Phenomena, Cartilage, Articular, Femur, Humans, Knee Injuries, Knee Joint, Magnetic Resonance Imaging, Male, Models, Theoretical, Rotation, Rupture, Tibia, Reproducibility of Results, Range of Motion, Articular, Anterior Cruciate Ligament, Soft Tissue Injuries
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