The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
Biomarkers associated with COVID-19 disease progression
Open accessAbstract
The coronavirus disease 2019 (COVID-19) pandemic is a scientific, medical, and social challenge. The complexity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is centered on the unpredictable clinical course of the disease that can rapidly develop, causing severe and deadly complications. The identification of effective laboratory biomarkers able to classify patients based on their risk is imperative in being able to guarantee prompt treatment. The analysis of recently published studies highlights the role of systemic vasculitis and cytokine mediated coagulation disorders as the principal actors of multi organ failure in patients with severe COVID-19 complications. The following biomarkers have been identified: hematological (lymphocyte count, neutrophil count, neutrophil-lymphocyte ratio (NLR)), inflammatory (C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT)), immunological (interleukin (IL)-6 and biochemical (D-dimer, troponin, creatine kinase (CK), aspartate aminotransferase (AST)), especially those related to coagulation cascades in disseminated intravascular coagulation (DIC) and acute respiratory distress syndrome (ARDS). New laboratory biomarkers could be identified through the accurate analysis of multicentric case series; in particular, homocysteine and angiotensin II could play a significant role.
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Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
Martínez González, M. (2020) · DSPACE System - Metalibrary (University of the Coast) · Cited by 18,463
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COVID-19: consider cytokine storm syndromes and immunosuppression
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Double-slit photoelectron interference in strong-field ionization of the neon dimer
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Double-slit photoelectron interference in strong-field ionization of the neon dimer
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Cited by
Autopsy in suspected COVID-19 cases
Hanley, B., Lucas, S. B., Youd, E., Swift, B., & Osborn, M. (2020) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2020-206522 · Cited by 478
Sabaka, P., Koščálová, A., Straka, I., Hodosy, J., Lipták, R., Kmotorková, B., Kachlíková, M., & Kušnírová, A. (2021) · BMC Infectious Diseases · doi:10.1186/s12879-021-05945-8 · Cited by 130
Goud, P. T., Bai, D., & Abu-Soud, H. M. (2021) · International Journal of Biological Sciences · doi:10.7150/ijbs.51811 · Cited by 88
Retracted: Neutrophil/lymphocyte ratio—A marker of COVID‐19 pneumonia severity
(2020) · doi:10.1111/ijcp.13698 · Cited by 88
RetractedThe hormetic and hermetic role of IL-6
Forcina, L., Franceschi, C., & Musarò, A. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101697 · Cited by 85
Metadata
- Authors
- Ponti, G., Maccaferri, M., Ruini, C., Tomasi, A., & Ozben, T.
- Venue
- Critical Reviews in Clinical Laboratory Sciences
- Publisher
- Informa UK Limited
- Published
- 2020-06-05
- Volume
- 57
- Issue
- 6
- Pages
- 389-399
- ISSN
- 1040-8363 (ISSN-L)
- 1549-781X
- OpenAlex
- W3033072986
- Cited by
- 890
- References
- 109
- FWCI
- 9.79
- Type
- journal article
- Language
- en
- Open access
- green
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- Ponti, G., Maccaferri, M., Ruini, C., Tomasi, A., & Ozben, T. (2020). Biomarkers associated with COVID-19 disease progression. Critical Reviews in Clinical Laboratory Sciences. https://doi.org/10.1080/10408363.2020.1770685
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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