The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Nutraceutical Functions of Sesame: A Review
Abstract
The results of recent food chemical and nutraceutical studies on the traditionally well-known health value of sesame are described, including some aspects of the utilization of sesame. The highly antioxidative activity of sesame oil was clarified and found to involve newly discovered lignans. The antiaging effect of sesame was elucidated to be due to the strong vitamin E activity caused by a novel synergistic effect of sesame lignans with tocopherols resulting from the inhibition of metabolic decomposition of tocopherols by sesame lignans. The specific inhibitory action of sesame lignans on Delta5 desaturase in polyunsaturated fatty acid synthesis was found in studies on the microbial production of polyunsaturated fatty acids. This effect of sesame lignans was extended to various effects on fatty acid metabolism involving lowering fatty acid concentration in liver and serum due to acceleration of fatty acid oxidation and suppression of fatty acid synthesis, and the controlling influence on the ratio of n-6/n-3 polyunsaturated fatty acids under excess intake of either n-6 or n-3 fatty acids in the diet. Sesame lignans lowered the cholesterol concentration in serum, especially in combination with tocopherol, due to the inhibition of absorption from the intestine and suppression of synthesis in the liver. Sesame lignans also showed other useful functions such as acceleration of alcohol decomposition in the liver, antihypertensive activity, immunoregulatory activities, anticarcinogenic activity, and others.
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Cites
A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease
Sano, M., Ernesto, C., Thomas, R. G., Klauber, M. R., Schafer, K., Grundman, M., Woodbury, P., Growdon, J., Cotman, C. W., Pfeiffer, E., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704243361704 · Cited by 2,380
Antioxidants/antimutagens in food
Namiki, M. (1990) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408399009527528 · Cited by 901
Self-citationA new murine model of accelerated senescence
TAKEDA, T., HOSOKAWA, M., TAKESHITA, S., IRINO, M., HIGUCHI, K., MATSUSHITA, T., TOMITA, Y., YASUHIRA, K., HAMAMOTO, H., & SHIMIZU, K. (1981) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(81)90084-1 · Cited by 874
Cytochrome P450 ω-Hydroxylase Pathway of Tocopherol Catabolism
Sontag, T. J., & Parker, R. S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201466200 · Cited by 458
Tocotrienol: a review of its therapeutic potential
Theriault, A., Chao, J.-T., Wang, Q., Gapor, A., & Adeli, K. (1999) · Clinical Biochemistry · doi:10.1016/s0009-9120(99)00027-2 · Cited by 346
The chemistry and physiological functions of sesame
Namiki, M. (1995) · Food Reviews International · doi:10.1080/87559129509541043 · Cited by 339
Self-citationInhibition of cholesterol absorption and synthesis in rats by sesamin
Hirose, N., Inoue, T., Nishihara, K., Sugano, M., Akimoto, K., Shimizu, S., & Yamada, H. (1991) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42050-4 · Cited by 298
Contribution of lignan analogues to antioxidative activity of refined unroasted sesame seed oil
Fukuda, Y., Nagata, M., Osawa, T., & Namiki, M. (1986) · Journal of the American Oil Chemists' Society · doi:10.1007/bf02673792 · Cited by 270
Self-citationHypocholesterolemic effect of sesame lignan in humans
Hirata, F., Fujita, K., Ishikura, Y., Hosoda, K., Ishikawa, T., & Nakamura, H. (1996) · Atherosclerosis · doi:10.1016/0021-9150(95)05769-2 · Cited by 234
Novel Antioxidative Metabolites in Rat Liver with Ingested Sesamin
Nakai, M., Harada, M., Nakahara, K., Akimoto, K., Shibata, H., Miki, W., & Kiso, Y. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0258961 · Cited by 217
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n‐3 Omega fatty acids: a review of current knowledge
Gogus, U., & Smith, C. (2010) · International Journal of Food Science & Technology · doi:10.1111/j.1365-2621.2009.02151.x · Cited by 358
Herb and Spices in Colorectal Cancer Prevention and Treatment: A Narrative Review
Hossain, M. S., Kader, M. A., Goh, K. W., Islam, M., Khan, M. S., Harun-Ar Rashid, M., Ooi, D. J., Melo Coutinho, H. D., Al-Worafi, Y. M., Moshawih, S., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.865801 · Cited by 346
Wang, Z., Ma, X., Li, J., & Cui, X. (2016) · Experimental Gerontology · doi:10.1016/j.exger.2016.07.001 · Cited by 39
Metadata
- Authors
- Namiki, M.
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2007-09-27
- Volume
- 47
- Issue
- 7
- Pages
- 651-673
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W2087940886
- Cited by
- 332
- References
- 74
- FWCI
- 8.09
- Type
- journal article
- Language
- en
- Open access
- closed
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