Cited by 137Fatty Acid Research and HealthEdible Oils Quality and AnalysisLipid metabolism and biosynthesis

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Systematic evaluation on the effectiveness of conjugated linoleic acid in human health

Fuke, Gitane, Nornberg, José Laerte·2017·Critical Reviews in Food Science and Nutrition

DOI 10.1080/10408398.2012.716800

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Abstract

The term CLA (conjugated linoleic acid) corresponds to a mixture of positional and geometric isomers of linoleic acid. Two of these isomers (9c, 11t and 10t, 12c) have biological activity. The milk and dairy products are the most abundant source of conjugated linoleic acid, which refers to a group of positional and geometric isomers of CLA (CLA 18:2 cis-9, cis-12). The following research aims to approach aspects regarding the CLA, as well as its relationship with diseases. Conjugated linoleic acids have been studied for their beneficial effects in the prevention and treatment of many diseases, including obesity, cancer, diabetes, and cardiovascular diseases. Scientific information put together the physiological properties of CLA, which serves as inputs to claim their potential as functional ingredients to be used in the prevention and control of several chronic metabolic disorders.

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Authors: Fuke, G., & Nornberg, J. L.
Affiliations: Universidade Federal de Santa Maria (BR)
Departamento de Ciência e Tecnologia de Alimentos Endereço, Endereço, Campus Universitário - Centro de Ciências Rurais Prédio, Santa Maria, Brazil
Corresponding author: Fuke, Gitane
Venue: Critical Reviews in Food Science and Nutrition
Publisher: Informa UK Limited
Published: 2016-09-16
Volume: 57
Issue: 1
Pages: 1-7
ISSN: 1040-8398 (ISSN-L)
1549-7852
DOI: 10.1080/10408398.2012.716800
OpenAlex: W2520860049
Cited by: 137
References: 69
Citations by year: 2026: 5 · 2025: 10 · 2024: 15 · 2023: 15 · 2022: 20 · 2021: 18 · 2020: 16 · 2019: 18 · 2018: 16 · 2017: 4
FWCI: 13.22
Type: journal article
Language: en
Open access: closed
Locations: Critical Reviews in Food Science and Nutrition (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
Keywords: conjugated linoleic acid, CLA isomers, dairy products, functional food ingredients, obesity, cancer, diabetes mellitus, cardiovascular disease, chronic metabolic disorders, disease prevention
MeSH terms: Animals, Body Composition, Chronic Disease, Dairy Products, Humans, Insulin Resistance, Stereoisomerism, Molecular Structure, Anticarcinogenic Agents, Evidence-Based Medicine, Dietary Supplements, Linoleic Acids, Conjugated, Lipid Metabolism, Functional Food

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Systematic evaluation on the effectiveness of conjugated linoleic acid in human health

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