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Resveratrol as an anti-cancer agent: A review
Abstract
Owing to their antimicrobial, antioxidant, and anti-inflammatory activity, grapes (Vitis vinifera L.) are the archetypal paradigms of fruits used not only for nutritional purposes, but also for exclusive therapeutics. Grapes are a prominent and promising source of phytochemicals, especially resveratrol, a phytoalexin antioxidant found in red grapes which has both chemopreventive and therapeutic effects against various ailments. Resveratrol's role in reducing different human cancers, including breast, cervical, uterine, blood, kidney, liver, eye, bladder, thyroid, esophageal, prostate, brain, lung, skin, gastric, colon, head and neck, bone, ovarian, and cervical, has been reviewed. This review covers the literature that deals with the anti-cancer mechanism of resveratrol with special reference to antioxidant potential. Furthermore, this article summarizes the literature pertaining to resveratrol as an anti-cancer agent.
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Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
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“This compound has become very popular due to its anti-cancer potential, first reported in 1997 (Jang et al., 1997).”
BackgroundSmall molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
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Cited by
Potential Adverse Effects of Resveratrol: A Literature Review
Shaito, A., Posadino, A. M., Younes, N., Hasan, H., Halabi, S., Alhababi, D., Al-Mohannadi, A., Abdel-Rahman, W. M., Eid, A. H., Nasrallah, G. K., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21062084 · Cited by 716
Hoang, H. T., Moon, J.-Y., & Lee, Y.-C. (2021) · Cosmetics · doi:10.3390/cosmetics8040106 · Cited by 329
A comprehensive review of the health perspectives of resveratrol
Rauf, A., Imran, M., Suleria, H. A. R., Ahmad, B., Peters, D. G., & Mubarak, M. S. (2017) · Food & Function · doi:10.1039/c7fo01300k · Cited by 286
Self-citationValorization of Food Waste to Produce Value-Added Products Based on Its Bioactive Compounds
Liu, Z., de Souza, T. S. P., Holland, B., Dunshea, F., Barrow, C., & Suleria, H. A. R. (2023) · Processes · doi:10.3390/pr11030840 · Cited by 254
Teka, T., Zhang, L., Ge, X., Li, Y., Han, L., & Yan, X. (2022) · Phytochemistry · doi:10.1016/j.phytochem.2022.113128 · Cited by 216
Metadata
- Authors
- Rauf, A., Imran, M., Butt, M. S., Nadeem, M., Peters, D. G., & Mubarak, M. S.
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2017-07-21
- Volume
- 58
- Issue
- 9
- Pages
- 1428-1447
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W2567423087
- Cited by
- 663
- References
- 4
- FWCI
- 11.09
- Type
- journal article
- Language
- en
- Open access
- closed
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