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Cited by 300

The DOI matches its Crossref record; 216 of the 216 references it cites were found in a registry or an index.

Application of different nanocarriers for encapsulation of curcumin

Rafiee, Zahra, Nejatian, Mohammad, Daeihamed, Marjan, Jafari, Seid Mahdi·2019·Critical Reviews in Food Science and Nutrition

Abstract

Curcumin is the main polyphenol of the curcuminoid class of turmeric, a well-known spice belonging to the ginger family. In addition to its common applications like coloring and antioxidant agent as food additives, it has a broad range of favorable biological functions, such as anti-inflammatory, anti-microbial, anti-diabetic activities, and anti-cancer potentials against various cancers. However, curcumin suffers from some limitations including short shelf life due to its poor chemical stability, low bioavailability due to its poor absorption, low water solubility, rapid metabolism and rapid systemic elimination. Nanoencapsulaion has been addressed as an innovative and emerging technology for resolving these shortcomings. In this review, the different delivery systems used for loading of curcumin have been considered and explained including lipid-based, chemical polymer and biopolymer-based, nature-inspired, special equipment-based and surfactant-based techniques. Also, implications of nanoencapsulated curcumin in food, pharmaceutical and cosmetic uses are discussed. In this sense, the relevant recent studies in the past few years along with upcoming challenges have been covered. Although incorporation of curcumin into nanocarriers can be a possible solution to overcome its inherent constraints, there are some rational concerns about their toxicological safety once they enter into the biological paths. Therefore, future investigations could focus on assessment of their biological fate during digestion and absorption within human body.

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Crossref · 10.1080/10408398.2018.1495174

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Metadata

Authors
Rafiee, Z., Nejatian, M., Daeihamed, M., & Jafari, S. M.
Venue
Critical Reviews in Food Science and Nutrition
Published
2018-10-04
Volume
59
Issue
21
Pages
3468-3497
ISSN
  • 1040-8398 (ISSN-L)
  • 1549-7852
OpenAlex
W2884699912
Cited by
300
References
216
FWCI
11.28
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Application of different nanocarriers for encapsulation of curcumin. https://app.cochat.ai/papers/10.1080/10408398.2018.1495174
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Rafiee, Z., Nejatian, M., Daeihamed, M., & Jafari, S. M. (2019). Application of different nanocarriers for encapsulation of curcumin. Critical Reviews in Food Science and Nutrition. https://doi.org/10.1080/10408398.2018.1495174

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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