Comparison of nocturnal blood pressure based on home versus ambulatory blood pressure measurement: The Ohasama Study
Open accessAbstract
Objectives The nocturnal blood pressure (BP) is a strong predictor of hypertensive target organ damage including that in cardiovascular diseases. The use of ambulatory BP (ABP) monitoring has enabled the evaluation of nocturnal BP and detection of non-dippers. This study compared nocturnal BP values, nocturnal decline in BP, and the prevalence of non-dippers based on ABP and home BP (HBP) measurements in a general population. Methods Data on HBP measured with HEM 747-IC-N (Omron Healthcare Co., Ltd.) and 24-hour ABP measured with ABPM-630 (Nippon Colin) were obtained from fifty-five participants aged ≥ 20 years (mean age: 65.1 years, 78.2% women). To exclude a systematic difference between the two methods, we conducted a validation study for HBP and ABP in another population that consisted of hypertensive outpatients (mean age: 65.4 years, 53.4% women). Results After adjusting for the systematic difference in BP between the two methods calculated in the validation study (3.9 mmHg for systolic and 3.0 mmHg for diastolic), morning and daytime (average of morning and evening) HBP were significantly lower than morning (average of 2 h after waking) and daytime (average of being awake) ABP, respectively. No significant difference was found in nocturnal BP between HBP and ABP monitoring regardless of the quality of sleep during nocturnal HBP measurement. Agreement between HBP and ABP in the detection of non-dippers was low mainly due to the difference in daytime BP values. Conclusio…
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The measurement of asleep BP is made possible by a few models of HBPM, which is better tolerated and provides nocturnal BP readings and predicts cardiovascular events similar to those observed using ABPM.
“However, the measurement of asleep BP is made possible by a few models of HBPM, which is better tolerated and provides nocturnal BP readings and predicts cardiovascular events similar to those observed using ABPM. 48,61”
Cites
2013 ESH/ESC Guidelines for the management of arterial hypertension
Authors Task Force Members, Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Böhm, M., Christiaens, T., Cífková, R., Backer, G. D., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht151 · Cited by 13,638 · see citing works
2018 ESC/ESH Guidelines for the management of arterial hypertension
Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy339 · Cited by 10,286 · see citing works
Ohkubo, T., Hozawa, A., Yamaguchi, J., Kikuya, M., Ohmori, K., Michimata, M., Matsubara, M., Hashimoto, J., Hoshi, H., Araki, T., et al. (2002) · Journal of Hypertension · doi:10.1097/00004872-200211000-00017 · Cited by 1,053 · see citing works
Self-citationOhkubo, T., Imai, Y., Tsuji, I., Nagai, K., Kato, J., Kikuchi, N., Nishiyama, A., Aihara, A., Sekino, M., Kikuya, M., et al. (1998) · Journal of Hypertension · doi:10.1097/00004872-199816070-00010 · Cited by 782 · see citing works
Self-citationPrognostic Significance for Stroke of a Morning Pressor Surge and a Nocturnal Blood Pressure Decline
Metoki, H., Ohkubo, T., Kikuya, M., Asayama, K., Obara, T., Hashimoto, J., Totsune, K., Hoshi, H., Satoh, H., & Imai, Y. (2005) · Hypertension · doi:10.1161/01.hyp.0000198541.12640.0f · Cited by 407 · see citing works
Self-citationLeung, A. A. C., Daskalopoulou, S. S., Dasgupta, K., McBrien, K., Butalia, S., Zarnke, K. B., Nerenberg, K. A., Harris, K. C., Nakhla, M. M., Cloutier, L., et al. (2017) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2017.03.005 · Cited by 318 · see citing works
Ohkubo, T., Asayama, K., Kikuya, M., Metoki, H., Hoshi, H., Hashimoto, J., Totsune, K., Satoh, H., & Imai, Y. (2004) · Journal of Hypertension · doi:10.1097/00004872-200406000-00009 · Cited by 287 · see citing works
Self-citationNocturnal blood pressure and cardiovascular disease: a review of recent advances
Yano, Y., & Kario, K. (2012) · Hypertension Research · doi:10.1038/hr.2012.26 · Cited by 227 · cited 1× · see citing works
“In addition, a blunted decrease in nocturnal BP (ie, non-dipping status) has been associated with an increased risk of cardiovascular morbidity and mortality (2).”
BackgroundImai, Y., Kario, K., Shimada, K., Kawano, Y., Hasebe, N., Matsuura, H., Tsuchihashi, T., Ohkubo, T., Kuwajima, I., & Miyakawa, M. (2012) · Hypertension Research · doi:10.1038/hr.2012.56 · Cited by 204 · see citing works
Self-citationCuspidi, C., Meani, S., Salerno, M., Valerio, C., Fusi, V., Severgnini, B., Lonati, L. M., Magrini, F., & Zanchetti, A. (2004) · Journal of Hypertension · doi:10.1097/00004872-200402000-00010 · Cited by 195 · see citing works
Imai, Y., Satoh, H., Nagai, K., Sakuma, M., Sakuma, H., Minami, N., Munakata, M., Hashimoto, J., Yamagishi, T., Watanabe, N., et al. (1993) · Journal of Hypertension · doi:10.1097/00004872-199312000-00017 · Cited by 172 · see citing works
Self-citationDolan, E., Stanton, A. V., Thom, S., Caulfield, M. J., Atkins, N., McInnes, G. T., Collier, D., Dicker, P., & O'Brien, E. T. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e328322cd62 · Cited by 128 · see citing works
Nighttime Home Blood Pressure and the Risk of Hypertensive Target Organ Damage
Ishikawa, J., Hoshide, S., Eguchi, K., Ishikawa, S., Shimada, K., Kario, K., & for the Japan Morning Surge-Home Blood Pressure Study Investigators Group (2012) · Hypertension · doi:10.1161/hypertensionaha.112.198101 · Cited by 123 · see citing works
Asayama, K., Ohkubo, T., Kikuya, M., Metoki, H., Hoshi, H., Hashimoto, J., Totsune, K., Satoh, H., & Imai, Y. (2004) · Stroke · doi:10.1161/01.str.0000141679.42349.9f · Cited by 123 · see citing works
Self-citationReproducibility of Home Blood Pressure Measurements Over a 1-Year Period
Sakuma, M. (1997) · American Journal of Hypertension · doi:10.1016/s0895-7061(97)00117-9 · Cited by 122 · see citing works
Device for the self-measurement of blood pressure that can monitor blood pressure during sleep
Chonan, K., Kikuya, M., Araki, T., Fujiwara, T., Suzuki, M., Michimata, M., Hashimoto, J., Ohkubo, T., Hozawa, A., Yamamoto, N., et al. (2001) · Blood Pressure Monitoring · doi:10.1097/00126097-200108000-00008 · Cited by 95 · see citing works
Self-citationKollias, A., Ntineri, A., & Stergiou, G. S. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001189 · Cited by 90 · see citing works
Kollias, A., Kyriakoulis, K. G., Stambolliu, E., Ntineri, A., Anagnostopoulos, I., & Stergiou, G. S. (2020) · Journal of Hypertension · doi:10.1097/hjh.0000000000002355 · Cited by 82 · see citing works
Imai, Y., Abe, K., Sasaki, S., Mxnami, N., Munakata, M., Sekino, H., Nihei, M., & YOSHINAGA, K. (1990) · American Journal of Hypertension · doi:10.1093/ajh/3.4.293 · Cited by 78 · see citing works
Self-citationHanazawa, T., Asayama, K., Watabe, D., Tanabe, A., Satoh, M., Inoue, R., Hara, A., Obara, T., Kikuya, M., Nomura, K., et al. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.117.008509 · Cited by 60 · see citing works
Self-citationSeasonal Variation in Home Blood Pressure Measurements and Relation to Outside Temperature in Japan
Hozawa, A., Kuriyama, S., Shimazu, T., Ohmori‐Matsuda, K., & Tsuji, I. (2011) · Clinical and Experimental Hypertension · doi:10.3109/10641963.2010.531841 · Cited by 60 · see citing works
Viera, A. J., Lingley, K., & Hinderliter, A. L. (2011) · BMC Medical Research Methodology · doi:10.1186/1471-2288-11-59 · Cited by 59 · see citing works
Stergiou, G. S., Nasothimiou, E. G., Destounis, A., Poulidakis, E., Evagelou, I., & Tzamouranis, D. (2012) · American Journal of Hypertension · doi:10.1038/ajh.2012.82 · Cited by 55 · see citing works
Reproducibility of Nocturnal Blood Pressure Assessed by Self-Measurement of Blood Pressure at Home
Hosohata, K., Kikuya, M., Ohkubo, T., Metoki, H., Asayama, K., Inoue, R., Obara, T., Hashimoto, J., Totsune, K., Hoshi, H., et al. (2007) · Hypertension Research · doi:10.1291/hypres.30.707 · Cited by 51 · see citing works
Self-citationImai, Y., Nihei, M., Abe, K., Sasaki, S., Minami, N., Munakata, M., Yumita, S., Onoda, Y., Sekino, H., Yamakoshi, K., et al. (1987) · Clinical and Experimental Hypertension · doi:10.3109/10641968709159072 · Cited by 50 · see citing works
Self-citationIshikawa, J., Shimizu, M., Edison, E. S., Yano, Y., Hoshide, S., Eguchi, K., & Kario, K. (2013) · Journal of Hypertension · doi:10.1097/hjh.0b013e328365c8a8 · Cited by 45 · see citing works
Ushio, H., Ishigami, T., Araki, N., Minegishi, S., Tamura, K., Okano, Y., Uchino, K., Tochikubo, O., & Umemura, S. (2009) · Clinical and Experimental Nephrology · doi:10.1007/s10157-009-0192-4 · Cited by 41 · see citing works
Night-time home versus ambulatory blood pressure in determining target organ damage
Andreadis, E. A., Agaliotis, G. D., Κόλλιας, Α., Kolyvas, G. N., Achimastos, A. D., & Stergiou, G. S. (2016) · Journal of Hypertension · doi:10.1097/hjh.0000000000000815 · Cited by 36 · see citing works
Kollias, A., Andreadis, E., Agaliotis, G., Kolyvas, G. N., Achimastos, A., & Stergiou, G. S. (2018) · Journal of Hypertension · doi:10.1097/hjh.0000000000001562 · Cited by 34 · see citing works
Imai, Y., Ohkubo, T., Tsuji, I., Hozawa, A., Nagai, K., Kikuya, M., Aihara, A., Sekino, M., Michimata, M., Matsubara, M., et al. (1999) · Hypertension Research · doi:10.1291/hypres.22.261 · Cited by 34 · see citing works
Self-citationLindroos, A. S., Johansson, J. K., Puukka, P. J., Kantola, I. M., Salomaa, V. V., Juhanoja, E. P., Sivén, S. S. E., Jousilahti, P., Jula, A., & Niiranen, T. (2016) · Journal of Hypertension · doi:10.1097/hjh.0000000000000995 · Cited by 31 · see citing works
Side effects of ambulatory blood pressure monitoring
van der Steen, M. S., Lenders, J. W. M., & Thien, T. A. (2005) · Blood Pressure Monitoring · doi:10.1097/00126097-200506000-00007 · Cited by 27 · see citing works
How many times should we ask subjects to measure blood pressure at home on each occasion?
Imai, Y., Obara, T., & Ohkubo, T. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e3282170aef · Cited by 26 · see citing works
Self-citationSatoh, M., Hosaka, M., Asayama, K., Kikuya, M., Inoue, R., Metoki, H., Utsugi, M. T., Hara, A., Hirose, T., Obara, T., et al. (2014) · Clinical and Experimental Hypertension · doi:10.3109/10641963.2014.892121 · Cited by 19 · see citing works
Self-citationKuwabara, M., Harada, K., Hishiki, Y., & Kario, K. (2019) · Blood Pressure Monitoring · doi:10.1097/mbp.0000000000000368 · Cited by 14 · see citing works
Clinical Significance and Cost-Effectiveness of 24-hour Ambulatory Blood Pressure Monitoring.
Imai, Y. (1995) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.176.1 · Cited by 13 · see citing works
Self-citationLindroos, A. S., Kantola, I. M., Salomaa, V. V., Juhanoja, E. P., Sivén, S. S. E., Jousilahti, P., Jula, A., & Niiranen, T. (2019) · American Journal of Hypertension · doi:10.1093/ajh/hpz062 · Cited by 12 · see citing works
Pai, A. U., Chakrapani, M., Bhaskaran, U., & Kamath, P. K. (2012) · PubMed · Cited by 9 · see citing works
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- Authors
- Hosohata, K., Kikuya, M., Asayama, K., Metoki, H., Imai, Y., & Ohkubo, T.
- Affiliations
- Osaka University of Pharmaceutical Sciences (JP)
- Teikyo University (JP)
- Tohoku Medical and Pharmaceutical University (JP)
- Tohoku Institute for Management of Blood Pressure (JP)
- Corresponding author
- Ohkubo, Takayoshi
- Venue
- Clinical and Experimental Hypertension
- Publisher
- Informa UK Limited
- Published
- 2020-06-11
- Volume
- 42
- Issue
- 8
- Pages
- 685-691
- ISSN
- 0148-3927 (ISSN-L)
- 1064-1963
- 1525-6006
- OpenAlex
- W3033117275
- Cited by
- 16
- References
- 38
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 5 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 2
- FWCI
- 0.93
- Type
- journal article
- Language
- en
- Open access
- Licence
- cc-by-nc-nd
- Locations
- Clinical and Experimental Hypertension (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Institutional Repositories DataBase (IRDB) (submittedVersion, cc-by-nc-nd)
- Lirias (submittedVersion, other-oa)
- Funders
- Comprehensive Research on Cardiovascular and Life-Style Related
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Keywords
- nocturnal blood pressure, home blood pressure monitoring, ambulatory blood pressure monitoring, non-dippers, nocturnal blood pressure dipping, measurement agreement, hypertension, hypertensive target organ damage, sleep quality, Ohasama study
- MeSH terms
- Aged, Blood Pressure, Blood Pressure Determination, Female, Humans, Hypertension, Male, Middle Aged, Outpatients, Sleep, Prevalence, Blood Pressure Monitoring, Ambulatory
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