The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Schiff bases in medicinal chemistry: a patent review (2010-2015)
Abstract
INTRODUCTION: Schiff bases are synthetically accessible and structurally diverse compounds, typically obtained by facile condensation between an aldehyde, or a ketone with primary amines. Schiff bases contain an azomethine (-C = N-) linkage that stitches together two or more biologically active aromatic/heterocyclic scaffolds to form various molecular hybrids with interesting biological properties. Schiff bases are versatile metal complexing agents and have been known to coordinate all metals to form stable metal complexes with vast therapeutic applications. Areas covered: This review aims to provide a comprehensive overview of the various patented therapeutic applications of Schiff bases and their metal complexes from 2010 to 2015. Expert opinion: Schiff bases are a popular class of compounds with interesting biological properties. Schiff bases are also versatile metal complexing ligands and have been used to coordinate almost all d-block metals as well as lanthanides. Therapeutically, Schiff bases and their metal complexes have been reported to exhibit a wide range of biological activities such as antibacterial including antimycobacterial, antifungal, antiviral, antimalarial, antiinflammatory, antioxidant, pesticidal, cytotoxic, enzyme inhibitory, and anticancer including DNA damage.
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Cited by
Mahmoudi, C., Tahraoui Douma, N., Mahmoudi, H., Iurciuc (Tincu), C. E., & Popa, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147839 · Cited by 57
Metadata
- Authors
- Hameed, A., al-Rashida, M., Uroos, M., Abid Ali, S., & Khan, K. M.
- Venue
- Expert Opinion on Therapeutic Patents
- Publisher
- Informa UK Limited
- Published
- 2016-11-07
- Volume
- 27
- Issue
- 1
- Pages
- 63-79
- ISSN
- 1354-3776 (ISSN-L)
- 1744-7674
- OpenAlex
- W2538154912
- Cited by
- 401
- References
- 45
- FWCI
- 6.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hameed, A., al-Rashida, M., Uroos, M., Abid Ali, S., & Khan, K. M. (2017). Schiff bases in medicinal chemistry: a patent review (2010-2015). Expert Opinion on Therapeutic Patents. https://doi.org/10.1080/13543776.2017.1252752
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
