The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Gestational diabetes: The forerunner for the development of maternal and childhood obesity and metabolic syndrome?
Abstract
OBJECTIVE: To examine the risk of obesity and metabolic syndrome in women with a history of gestational diabetes mellitus and in offspring born to mothers with gestational diabetes mellitus. METHODS: A review of studies examining the development of obesity, hypertension, metabolic abnormalities, metabolic syndrome, and type II diabetes in mothers with a history of gestational diabetes mellitus and control mothers, and offspring of mothers with a history of gestational diabetes and control mothers. RESULTS: Longitudinal studies demonstrate that women with a prior history of gestational diabetes mellitus and obesity are at significantly greater risk of developing metabolic syndrome than mothers with no history of gestational diabetes or obesity. The development of metabolic syndrome in children with increasing age is related to maternal gestational diabetes mellitus, maternal glycemia in the 3rd trimester, maternal obesity, neonatal macrosomia, and childhood obesity. CONCLUSIONS: The current prevalence of obesity in both adults and children and associated disorders of blood pressure and lipid metabolism, suggest a perpetuating cycle of increasing obesity, insulin resistance, and abnormal lipid metabolism, which has ominous consequences for future generations.
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“There is also a longer-term risk of obesity, type 2 diabetes, and cardiovascular disease in the child.”
From The Pathophysiology of Gestational Diabetes Mellitus (2018) · cites this paper as [67]
In the citing paper
“Children born to mothers with GDM have almost double the risk of developing childhood obesity when compared with nondiabetic mothers, even after adjusting for confounders such as maternal BMI [67,68]”
From The Pathophysiology of Gestational Diabetes Mellitus (2018) · cites this paper as [67]
Citations
Cites
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Cited by
Sorted by citations
The Pathophysiology of Gestational Diabetes Mellitus
Plows, J. F., Stanley, J. L., Baker, P. N., Reynolds, C. M., & Vickers, M. H. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19113342 · Cited by 1,874
“A recent study reported a 63% increased risk of CVD amongst women with a history of GDM, which was partly, but not fully, explained by BMI [59].”
BackgroundInfluentialGestational diabetes: the need for a common ground
Reece, E. A., Leguizamón, G. F., & Wiznitzer, A. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60515-8 · Cited by 599
Thompson, D. M., Berger, H. M., Feig, D. S., Gagnon, R. J., Kader, T., Keely, E., Kozak, S. E., Ryan, E. A., Sermer, M., & Vinokuroff, C. (2013) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2013.01.044 · Cited by 393
Gestational Diabetes Mellitus: A Harbinger of the Vicious Cycle of Diabetes
Alejandro, E. U., Mamerto, T. P., Chung, G., Villavieja, A., Gaus, N. L., Morgan, E., & Pineda-Cortel, M. R. B. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21145003 · Cited by 353
“The increased development of obesity observed in the offspring of mothers with GDM is also associated with an increased risk of metabolic disorders including cardiovascular diseases and insulin resistance [173].”
BackgroundThe fetal and maternal consequences of gestational diabetes mellitus
Reece, E. A. (2010) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767050903550659 · Cited by 316
“Vohr and Boney [19], for example, reviewed the medical literature to examine the risk of obesity and metabolic syndrome in women with a history of GDM in their offspring.”
Influential
Metadata
- Authors
- Vohr, B. R., & Boney, C. M.
- Affiliations
- Brown University (US)
- Corresponding author
- Vohr, Betty R.
- Venue
- The Journal of Maternal-Fetal & Neonatal Medicine
- Publisher
- Informa UK Limited
- Published
- 2008-01
- Volume
- 21
- Issue
- 3
- Pages
- 149-157
- ISSN
- 1476-4954 (ISSN-L)
- 1476-7058
- OpenAlex
- W2067953340
- Cited by
- 184
- References
- 50
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 5 · 2023: 5 · 2022: 11 · 2021: 6 · 2020: 9 · 2019: 9 · 2018: 9 · 2017: 13 · 2016: 12 · 2015: 10 · 2014: 14 · 2013: 9 · 2012: 16
- FWCI
- 18.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Maternal-Fetal & Neonatal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- gestational diabetes mellitus, maternal obesity, childhood obesity, metabolic syndrome, type 2 diabetes, hypertension, insulin resistance, neonatal macrosomia, maternal glycemia, offspring, intergenerational risk
- MeSH terms
- Adolescent, Child, Child, Preschool, Female, Humans, Infant, Longitudinal Studies, Obesity, Pregnancy, Prenatal Exposure Delayed Effects, Odds Ratio, Diabetes, Gestational, Metabolic Syndrome
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