The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Dyspnea and Activity Limitation in COPD: Mechanical Factors
Abstract
Dyspnea and activity limitation are the primary symptoms of chronic obstructive pulmonary disease and progress relentlessly as the disease advances. In COPD, dyspnea is multifactorial but abnormal dynamic ventilatory mechanics are believed to be important. Dynamic lung hyperinflation occurs during exercise in the majority of flow-limited patients with chronic obstructive pulmonary disease and may have serious sensory and mechanical consequences. This proposition is supported by several studies, which have shown a close correlation between indices of dynamic lung hyperinflation and measures of both exertional dyspnea and exercise performance. The strength of this association has been further confirmed by studies that have therapeutically manipulated this dependent variable. Relief of exertional dyspnea and improved exercise endurance following bronchodilator therapy correlate well with reduced lung hyperinflation. The mechanisms by which dynamic lung hyperinflation give rise to exertional dyspnea and exercise intolerance are complex. However, recent mechanistic studies suggest that dynamic lung hyperinflation-induced volume restriction and consequent neuromechanical uncoupling of the respiratory system are key mechanisms. This review examines, in some detail, the derangements of ventilatory mechanics that are peculiar to chronic obstructive pulmonary disease and attempts to provide a mechanistic rationale for the attendant respiratory discomfort and activity limitation.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Hyperinflation is clinically relevant for patients with COPD mainly because it contributes to dyspnea, exercise intolerance, skeletal muscle limitations, morbidity, and reduced physical activity levels associated with the disease.”
From Pathogenesis of hyperinflation in chronic obstructive pulmonary disease (2014) · cites this paper as [8]
Citations
Cites
American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation
Nici, L., Donner, C., Wouters, E., Zuwallack, R., Ambrosino, N., Bourbeau, J., Carone, M., Celli, B., Engelen, M., Fahy, B., et al. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200508-1211st · Cited by 1,966
Self-citationPain intensity processing within the human brain: a bilateral, distributed mechanism
Coghill, R. C., Sang, C. N., Maisog, J. M., & Iadarola, M. J. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.82.4.1934 · Cited by 1,077
Dynamic Hyperinflation and Exercise Intolerance in Chronic Obstructive Pulmonary Disease
O'DONNELL, D. E., REVILL, S. M., & WEBB, K. A. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.5.2012122 · Cited by 1,076
Self-citationEffects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD
O'Donnell, D. E., Flüge, T., Gerken, F., Hamilton, A., Webb, K., Aguilaniu, B., Make, B., & Magnussen, H. (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00116004 · Cited by 859
Self-citationRespiratory muscle work compromises leg blood flow during maximal exercise
Harms, C. A., Babcock, M. A., McClaran, S. R., Pegelow, D. F., Nickele, G. A., Nelson, W. B., & Dempsey, J. A. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.5.1573 · Cited by 711
Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography
Tataranni, P. A., Gautier, J., Chen, K., Uecker, A., Bandy, D. J., Salbe, A. D., Pratley, R. E., Lawson, M. A., Reiman, E. M., & Ravussin, É. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.8.4569 · Cited by 592
O'Donnell, D. E., & Webb, K. A. (1993) · American Review of Respiratory Disease · doi:10.1164/ajrccm/148.5.1351 · Cited by 543
Self-citationO'DONNELL, D. E., LAM, M., & WEBB, K. A. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.5.9804004 · Cited by 532 · cited 3×
“The rate and magnitude of DH during exercise is generally measured in the laboratory setting by serial inspiratory capacity (IC) measurements (3, 14, 25).”
BackgroundMethodSelf-citationO'DONNELL, D. E., LAM, M., & WEBB, K. A. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.2.9901038 · Cited by 485
Self-citationO’Donnell, D. E., Bertley, J. C., Chau, L. K. L., & Webb, K. A. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.1.9001298 · Cited by 432
Self-citation
Research works printed but not linked: 13
- O'Donnell D E, 1995, Current Therapy in Sports Medicine, 3rd ed, 678
- Pride N B, 1986, Handbook of Physiology, Section 3, Vol III, Part 2: The Respiratory System, 659
- Druz W S, 1981, J Appl Physiol, 51, 1522
- Dodd D S, 1984, Am Rev Respir Dis, 129, 33
- 10.1183/09031936.04.00072703 · DOI · Paper page
- Light R W, 1984, Am Rev Respir Dis, 130, 391
- 10.1164/ajrccm/151.3_Pt_1.751 · DOI
- Hong H, 1999, Am J Respir Crit Care Med, 159, A787
- Altose M D, 1989, Proc Int Union Physiol Sci, 17, 288
- Killian K J, 1985, Lung Biology in Health and Disease, vol 29, part B: The Thorax, 787
- Grassino A, 1979, Bull Eur Pathophysiol Respir, 15, 105
- Bye P T, 1985, Am Rev Respir Dis, 32, 236
- Kukorelli T, 1969, Acta Physiol Acad Sci Hung, 36, 261
Cited by
Sorted by citations
Items 101–200 of 220
Han, X., Li, P., Yang, Y., Liu, X., Xia, J., & Wu, W. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.691554 · Cited by 12
The difficulties of measuring and improving physical activity in COPD
Aguilaniu, B., & Roche, N. (2014) · npj Primary Care Respiratory Medicine · doi:10.1038/npjpcrm.2014.14 · Cited by 11
Klijn, P. H. C., Legemaat, M., Beelen, A., van Keimpema, A. R. J., Garrod, R., Bergsma, M., Paterson, B., Stuijfzand, A., & van Stel, H. F. (2015) · Medicine · doi:10.1097/md.0000000000002191 · Cited by 11
Doença pulmonar obstrutiva crônica e fatores associados em São Paulo, SP, 2008-2009
de Sousa, C. A., César, C. L. G., Barros, M. B. D. A., Carandina, L., Goldbaum, M., & Pereira, J. C. R. (2011) · Revista de Saúde Pública · doi:10.1590/s0034-89102011005000051 · Cited by 11
Exertional dyspnoea–ventilation relationship to discriminate respiratory from cardiac impairment
Plachi, F., Balzan, F. M., Fröhlich, L. F., Gass, R., Mendes, N. B. S., Schroeder, E., Berton, D. C., O’Donnell, D. E., & Neder, J. A. (2019) · European Respiratory Journal · doi:10.1183/13993003.01518-2019 · Cited by 10
Self-citationBarnes, P. J., & Rennard, S. I. (2009) · Elsevier eBooks · doi:10.1016/b978-0-12-374001-4.00034-1 · Cited by 10
Bains, D., Chahal, A., Shaphe, M. A., Kashoo, F. Z., Ali, T., Alghadir, A. H., & Khan, M. (2022) · BioMed Research International · doi:10.1155/2022/5528724 · Cited by 9
Patterns of cardiopulmonary response to exercise in COPD
O’Donnell, D. E., Elbehairy, A. F., Domnik, N. J., Vincent, S. G., Guenette, J. A., Webb, K. A., & Neder, J. A. (2018) · European Respiratory Society eBooks · doi:10.1183/2312508x.10011317 · Cited by 9
Self-citationvan Dijk, M., Klooster, K., Hartman, J. E., ten Hacken, N. H. T., & Slebos, D. (2020) · Lung · doi:10.1007/s00408-020-00382-x · Cited by 9
Karagiannis, C., Savva, C., Mamais, I., Adamide, T. A., Georgiou, A., & Xanthos, T. T. (2020) · Jornal Brasileiro de Pneumologia · doi:10.36416/1806-3756/e20190370 · Cited by 9
Beaulieu, J., Jensen, D., O’Donnell, D. E., Brouillard, C., Tracey, L., Vincent, S. G., Nadreau, É., Bernard, E., Bernard, S., & Maltais, F. (2020) · Therapeutic Advances in Respiratory Disease · doi:10.1177/1753466620939507 · Cited by 8
Self-citationKaragiannis, C., Savva, C., Korakakis, V., Adamide, T. A., Georgiou, A., Matheou, I., Prodromou, A., & Xanthos, T. T. (2021) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000620 · Cited by 8
Rogliani, P., Ritondo, B. L., Puxeddu, E., Cazzola, M., & Calzetta, L. (2021) · Respiratory Medicine · doi:10.1016/j.rmed.2021.106639 · Cited by 8
Fei, G., Tu, Y.-H., & Zhang, Y. (2015) · International Journal of COPD · doi:10.2147/copd.s77257 · Cited by 8
Are the “critical” inspiratory constraints actually decisive to limit exercise tolerance in COPD?
Marillier, M., Bernard, A., Gass, R., Berton, D. C., Vergès, S., O’Donnell, D. E., & Neder, J. A. (2020) · ERJ Open Research · doi:10.1183/23120541.00178-2020 · Cited by 7
Self-citationCommunity Participation by People with Chronic Obstructive Pulmonary Disease
Malaguti, C., Holland, A. E., McDonald, C. F., Mahal, A. S., Alison, J. A., Hill, C. J., Zanaboni, P., O’Halloran, P., Bondarenko, J., Macdonald, H., et al. (2021) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.1080/15412555.2021.1966761 · Cited by 8
Tsimouris, D., Arvanitidis, M., Moutzouri, M., Koumantakis, G. Α., Gioftsos, G., Παπανδρέου, Μ., & Grammatopoulou, E. P. (2023) · Respiratory Medicine and Research · doi:10.1016/j.resmer.2023.101002 · Cited by 7
Corriveau, S., Pond, G. R., Tang, G. H., & Goffin, J. R. (2021) · BMC Cancer · doi:10.1186/s12885-020-07719-y · Cited by 6
Impact of hypobaric flight simulation on walking distance and oxygenation in COPD patients
Dellweg, D., Schmitten, J., Kerl, J., Höhn, E., & Haidl, P. (2018) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2018.11.010 · Cited by 6
Effect of portable non-invasive ventilation on exercise tolerance in COPD: One size does not fit all
Chynkiamis, N., Armstrong, M., Hume, E., Alexiou, C., Snow, L., Lane, N. D., Hartley, T., Bourke, S. C., & Vogiatzis, I. (2020) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2020.103436 · Cited by 6
The physiology of breathlessness
Sylvester, K. P., Rolland‐Debord, C., Ong-Salvador, R., Stringer, W. W., & Bayat, S. (2022) · European Respiratory Society eBooks · doi:10.1183/2312508x.10012721 · Cited by 6
Dyspnea in bronchiectasis: a complex symptom of a complex disease
Martínez-Vergara, A., Girón, R. M., & Martínez‐García, M. Á. (2020) · Jornal Brasileiro de Pneumologia · doi:10.36416/1806-3756/e20200281 · Cited by 6
Choate, R., Holm, K. E., Sandhaus, R. A., Mannino, D. M., & Strange, C. (2024) · Respiratory Medicine · doi:10.1016/j.rmed.2024.107838 · Cited by 5
Fumat, R., Dupuis, M., Mallah, S., Héluain, V., Favard, F., Simonneau, Y., Dusselier, M., Barthes, R., Pontier, S., Collot, S., et al. (2023) · Respirology · doi:10.1111/resp.14488 · Cited by 5
Caron, M., Thériault, M., Debigaré, R., & Maltais, F. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-673-3_9 · Cited by 5
Koch, R., Augusto, T. R. D. L., Ramos, A. G., & Müller, P. D. T. (2020) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.1080/15412555.2020.1789085 · Cited by 5
Naz, İ., Aktaş, B., Sahin, H. D., & Kaya, D. Ö. (2022) · Heart & Lung · doi:10.1016/j.hrtlng.2022.03.005 · Cited by 5
History and Physical Examination
Schraufnagel, D. E., & Murray, J. F. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-4710-0.00017-1 · Cited by 5
Respiratory System Mechanics and Energetics
Henderson, W. R., Paré, P. A., & Ayas, N. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-3383-5.00005-1 · Cited by 6
Urban, T., Gassert, F. T., Frank, M., Schick, R. C., Bast, H., Bodden, J. H., Marka, A. W., Steinhelfer, L., Steinhardt, M., Sauter, A. P., et al. (2025) · European Radiology Experimental · doi:10.1186/s41747-025-00578-x · Cited by 4
Klijnhout, J. A., Mannée, D. C., van den Heuvel, M. M., van den Borst, B., & van Helvoort, H. A. (2022) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.1080/15412555.2022.2069554 · Cited by 4
Pathophysiology Updates for Chronic Obstructive Pulmonary Disease
Lan, L. T. T., & Dinh‐Xuan, A. T. (2013) · Current Respiratory Care Reports · doi:10.1007/s13665-013-0056-y · Cited by 4
Exercise Training and Pulmonary Rehabilitation in COPD
Tarigan, A. P., & Ananda, F. R. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.97704 · Cited by 4
Culver, B. H. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4557-0792-8.00003-9 · Cited by 4
PROGRAMAS DE EXERCÍCIO FÍSICO PARA PESSOAS COM DPOC: UMA REVISÃO SISTEMÁTICA
Lottermann, P. C., de Sousa, C. A., & de Liz, C. M. (2017) · Arquivos de Ciências da Saúde da UNIPAR · doi:10.25110/arqsaude.v21i1.2017.5340 · Cited by 3
Can an 86-year-old woman with advanced lung disease be a world class athlete?
Guenette, J. A., Lougheed, M. D., Webb, K. A., & O’Donnell, D. E. (2012) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2012.03.003 · Cited by 3
Self-citationIs Exercise Important in Chronic Obstructive Pulmonary Disease?
Make, B., & Casaburi, R. (2007) · COPD · doi:10.1080/15412550701471207 · Cited by 3
Rodríguez, I., & Zenteno, D. (2021) · Neumología Pediátrica · doi:10.51451/np.v9i1.388 · Cited by 3
A specific subtype of chronic obstructive pulmonary disease classified by forced vital capacity
Chen, C., He, Y. Z., Chen, Q., Zhang, D., Wang, Y., Tang, Y., Fang, Y., Zhong, N., Jian, W., & Zheng, J. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.12.06 · Cited by 2
COPD management: need for more consensus
Kardos, P. (2015) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(15)00156-3 · Cited by 3
Lung Function in Asthma, Chronic Obstructive Pulmonary Disease, and Lung Fibrosis
Janssens, W., & Bleyenbergh, P. V. (2020) · Wiley eBooks · doi:10.1002/9781118597309.ch37 · Cited by 3
Vieira, Y. P., da Silva, L. N., Nunes, B. P., Gonzalez, T. N., Duro, S. M. S., & Saes, M. D. O. (2025) · BMC Public Health · doi:10.1186/s12889-025-22208-2 · Cited by 2
An, W., Ning, S., Wang, J., Guo, D., Li, N., & Chu, X. (2025) · Journal of Medical Systems · doi:10.1007/s10916-025-02285-x · Cited by 2
Kronik Obstrüktif Akciğer Hastalığı Olan Bireylerde Dispne Şiddeti ve Etkileyen Faktörler
Helvaci, A., İzgü, N., & Özdemir, L. (2020) · Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi · doi:10.34087/cbusbed.684158 · Cited by 2
Danzo, F., Radovanovic, D., Gatti, M., Saad, M., Perotto, L., Franceschi, E., & Santus, P. (2022) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2022.2090343 · Cited by 2
Choi, J.-K., Yang, W., Lee, S.-W., Woo, S.-C., Kim, S., & Park, Y. (2024) · The Journal of Internal Korean Medicine · doi:10.22246/jikm.2024.45.1.11 · Cited by 3
Inspiratory muscle training for chronic obstructive pulmonary disease
Blakey, J., Hodgson, D., & Bolton, C. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009428.pub2 · Cited by 1
Nyberg, A., Lindström, B., & Wadell, K. (2013) · Physical Therapy Reviews · doi:10.1179/1743288x13y.0000000072 · Cited by 2
Tateishi, Y. (2011) · The Open Rehabilitation Journal · doi:10.2174/1874943701104010032 · Cited by 2
Bronchoscopic lung volume reduction
Slebos, D., Klooster, K., & ten Hacken, N. H. T. (2017) · European Respiratory Society eBooks · doi:10.1183/2312508x.10004117 · Cited by 2
Effect of expiratory loaded breathing during moderate exercise on intercostal muscle oxygenation
Bretonneau, Q., Pichon, A., & de Bisschop, C. (2020) · Multidisciplinary Respiratory Medicine · doi:10.4081/mrm.2020.702 · Cited by 2
Rubins, J. B., Raci, E. E., & Kunisaki, K. M. (2009) · Postgraduate Medicine · doi:10.3810/pgm.2009.01.1959 · Cited by 2
Exercise in Chronic Obstructive Pulmonary Disease
Laveneziana, P., & Palange, P. (2019) · Springer eBooks · doi:10.1007/978-3-030-05258-4_5 · Cited by 1
Self-citationImpact of cognitive functions on the quality of spirometry performance in patients with COPD
Yıldırım, G., Süerdem, M., Atalay, N. B., Kanat, F., & Tülek, B. (2020) · Eurasian Journal of Pulmonology · doi:10.4103/ejop.ejop_53_18 · Cited by 1
Alsubheen, S., Rodrigues, M., & Thorlund, K. (2025) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2025.2522754 · Cited by 1
Desanti, E., Jankowich, M. D., Choudhary, G., Morrison, A., Stanley, Z. K., Garshick, E., Moy, M. L., Kang, M., Wongtrakool, C., Sadikot, R. T., et al. (2025) · Pulmonary Circulation · doi:10.1002/pul2.70167 · Cited by 1
Rocha, H., Souza, R. F. B. D., Rocha, T. D. D. S., Alcoforado, L., Brandão, D. C., & de Andrade, A. D. (2025) · Journal of Chiropractic Medicine · doi:10.1016/j.jcm.2025.09.033 · Cited by 1
Asghar, A., Fonseca-Paricio, M., Ravikumar, N., Hammer, M. M., Forth, V. E., Wagh, A. A., Hogarth, D. K., & Shafiq, M. (2026) · Journal of Bronchology & Interventional Pulmonology · doi:10.1097/lbr.0000000000001067 · Cited by 1
Güneş, M., & Avcı, R. H. (2026) · Respiratory Medicine · doi:10.1016/j.rmed.2026.109024 · Cited by 1
Targeting Histone Deacetylases in Chronic Obstructive Pulmonary Disease
Barnes, P. J. (2011) · Springer eBooks · doi:10.1007/978-1-84882-644-1_14 · Cited by 1
Formoterol fumarate inhalation solution (Perforomist™) for COPD
Rubins, J. B. (2008) · Expert Review of Clinical Immunology · doi:10.1586/1744666x.4.4.415 · Cited by 1
Acute and short-term effect of an extra dose of formoterol in COPD patients.
Studart, F., Izbicki, M., Nery, L. E., Oliveira, L., Donner, C., Jardim, J., & Nascimento, O. (2012) · Respiratory Medicine · doi:10.1016/j.rmed.2011.12.015 · Cited by 1
Interventional Bronchoscopy in the Management of Chronic Obstructive Lung Disease
Bilaçeroğlu, S. (2019) · Current Respiratory Medicine Reviews · doi:10.2174/1573398x15666190211155026 · Cited by 1
Endobronchial Lung Volume Reduction Therapies
Holden, V. K., Alsunaid, S. R., Charya, A. V., Alghanim, F., Pickering, E. M., & Sachdeva, A. (2021) · Current Pulmonology Reports · doi:10.1007/s13665-020-00266-8 · Cited by 1
Respiratory Assist Devices in Pulmonary Rehabilitation
Criner, G. J. (2024) · Respiratory Care · doi:10.4187/respcare.11819 · Cited by 1
Bonnevie, T., Gravier, F., Smondack, P., Fresnel, E., Rivals, I., Brunel, H., Combret, Y., Médrinal, C., Prieur, G., Boujibar, F., et al. (2024) · Pulmonology · doi:10.1080/25310429.2024.2424649 · Cited by 1
Fateme, M., Dalvandi, A., Ebadi, A., Reza, K. H., Jörg, R., & Jamaati, H. (2018) · Journal of Patient Experience · doi:10.1177/2374373518796620 · Cited by 1
Kang, J.-I., Jeong, D., & Park, J.-S. (2019) · Journal of the Korean Society of Physical Medicine · doi:10.13066/kspm.2019.14.3.81 · Cited by 1
Steidl, E. M. D. S., Gonçalves, B. F. D. T., Rockenbach, N. D. M., Pasqualoto, A. S., & Mancopes, R. (2020) · Revista Contexto & Saúde · doi:10.21527/2176-7114.2020.38.210-216 · Cited by 1
Real life results of coil treatment for bronchoscopic lung volume reduction in emphysema
Turan, D., Doğan, D., Çörtük, M., Chouseın, E. G. U., Tanrıverdi, E., Yıldırım, B. Z., Demirkol, B., Çınarka, H., Özgül, M. A., & Çetınkaya, E. (2020) · Tuberkuloz ve Toraks · doi:10.5578/tt.69320 · Cited by 1
West, C. R. (2011) · Brunel University Research Archive (BURA) (Brunel University London) · Cited by 1
Annegarn, J. (2012) · Research Publications (Maastricht University) · doi:10.26481/dis.20121107ja
Επιπολασμός της χρόνιας αποφρακτικής πνευμονοπάθειας στην Κύπρο
Ζαχαριάδης, Α. (2013) · doi:10.12681/eadd/29243
Bronchopneumopathie chronique obstructive et activité physique
Coste, O., & Grillon, J.-L. (2009) · Elsevier eBooks · doi:10.1016/b978-2-294-70215-0.00011-9
Bustamante, L., Sívori, M., Lavagnino, D., Fraga, A. M., & Sáenz, C. (2011) · Redalyc (Universidad Autónoma del Estado de México)
Chapman, K. (2015) · Tuwhera (Auckland University of Technology)
Establishing Accessory Muscle Activation in Healthy Individuals During a Graded Exercise Test
Osterling, K. (2015) · DalSpace (Dalhousie University)
Yurach, M. T. (2014) · University Library - University of Saskatchewan (University of Saskatchewan)
Frisk, B. (2015) · NORA - Norwegian Open Research Archives
César, C. L. G., de Azevedo, M. B., Carandina, L., Goldbaum, M., César, J., & Pereira, R. (2011)
Definition, Pathophysiologie und Diagnostik der pulmonalen Hyperinflation
Sorichter, S., & Scholz, T. (2016) · Der Pneumologe · doi:10.1007/s10405-016-0083-9
Robles, P. (2016) · TSpace (University of Toronto)
Sharma, P. K. (2015) · Griffith Research Online · doi:10.25904/1912/1208
Polikutina, O. M., Slepynina, Y. S., Bazdyrev, E. D., Каретникова, В. Н., & Barbаrach, O. L. (2018) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2018-2-24-28
MCCONNELL, A. K. (2013) · Elsevier eBooks · doi:10.1016/b978-0-7020-5020-6.00003-0 · Cited by 1
Evaluation of the effect of interventions on exercise capacity in pulmonary patients
Puente‐Maestu, L. (2019) · Minerva Pneumologica · doi:10.23736/s0026-4954.18.01833-3
Souto‐Miranda, S. (2018) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
Punin, D. A., Milyagin, V. A., & IVANOVA, M. A. (2019) · The Bulletin of Contemporary Clinical Medicine · doi:10.20969/vskm.2019.12(6).54-59
Welling, J. B. A. (2020) · University of Groningen research database (University of Groningen / Centre for Information Technology) · doi:10.33612/diss.129343102
Effects of portable non-invasive ventilation on exercise tolerance in patients with COPD
Chynkiamis, N. (2020) · Northumbria Research Link (Northumbria University)
Dutta, A. (2021) · International Journal of Life Science and Pharma Research · doi:10.22376/ijpbs/lpr.2021.11.2.l172-179
Physiological mechanisms of exertional dyspnea in mild-to-moderate obesity
Pham, K. M. (2015) · eScholarship@McGill (McGill) · doi:10.82308/31516
Cas clinique n° 5 : Traitement de l’emphysème par valves endobronchiques
Egenod, T. (2021) · Revue des Maladies Respiratoires Actualités · doi:10.1016/s1877-1203(21)00010-0
Intra- and interobserver agreement of inspiratory capacity during cardio pulmonary exercise test
Mannée, D. C., Berens, T., van den Borst, B., & van Helvoort, H. A. (2021) · Pulmonology · doi:10.1016/j.pulmoe.2021.08.007
Stojkovic, J., Antova, E., & Stojkovikj, D. (2021) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2021.7942
Metadata
- Authors
- O'Donnell, D. E., & Laveneziana, P.
- Affiliations
- Queen's University (CA)
- Venue
- COPD: Journal of Chronic Obstructive Pulmonary Disease
- Publisher
- Informa UK Limited
- Published
- 2007-01
- Volume
- 4
- Issue
- 3
- Pages
- 225-236
- ISSN
- 1541-2555 (ISSN-L)
- 1541-2563
- OpenAlex
- W2158320806
- Cited by
- 220
- References
- 91
- Citations by year
- 2026: 12 · 2025: 9 · 2024: 8 · 2023: 5 · 2022: 8 · 2021: 15 · 2020: 22 · 2019: 17 · 2018: 16 · 2017: 14 · 2016: 11 · 2015: 19 · 2014: 12 · 2013: 10 · 2012: 12
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- COPD Journal of Chronic Obstructive Pulmonary Disease (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- chronic obstructive pulmonary disease, dyspnea, exertional dyspnea, activity limitation, respiratory mechanics, exercise intolerance, bronchodilator therapy
- MeSH terms
- Dyspnea, Humans, Pulmonary Ventilation, Total Lung Capacity, Respiratory Mechanics, Exercise Tolerance, Pulmonary Disease, Chronic Obstructive
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
