The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Circbank: a comprehensive database for circRNA with standard nomenclature
Open accessAbstract
Circular RNAs (circRNAs) represent a new type of regulatory RNA which forms a covalently closed continuous loop from back-splicing events, a process in which the downstream 5′ splice site and the 3′ splice site are covalently linked. Emerging evidence indicates that circRNAs exert a new layer of transcriptional and post-transcriptional regulation of gene expression. However, there is no standard nomenclature of circRNA, although the study of circRNAs has exploded in the past few years. Here we present circbank (www.circbank.cn), a comprehensive database for human circRNAs, where a novel naming system of circRNAs based on the host genes of circRNAs was implemented. In addition to the new naming system, circbank collected other five features of circRNAs including the miRNA binding site, conservation of circRNAs, m6A modification of circRNAs, mutation of circRNAs and protein-coding potential of circRNAs. Circbank is publicly available and allows users to query, browse and download circRNAs with all six features we provided, based on different search criteria. The database may serve as a resource to facilitate the research of function and regulation of circRNAs.
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Circular RNAs are a large class of animal RNAs with regulatory potency
Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature · doi:10.1038/nature11928 · Cited by 7,990
Natural RNA circles function as efficient microRNA sponges
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MicroRNA targets in Drosophila
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Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed
Rybak-Wolf, A., Stottmeister, C., Glažar, P., Jens, M., Pino, N., Giusti, S., Hanan, M., Behm, M., Bartok, O., Ashwal-Fluss, R., et al. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.03.027 · Cited by 2,423 · cited 3×
“CircRNAs were found to be expressed across various species including human, mouse, fly, worm, plant and yeast [3,5,28,29].”
BackgroundCirc-ZNF609 is a circular RNA that can be translated and functions in myogenesis
Legnini, I., Di Timoteo, G., Rossi, F., Morlando, M., Briganti, F., Sthandier, O., Fatica, A., Santini, T., Andronache, A., Wade, M., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.02.017 · Cited by 2,173
The Biogenesis, Functions, and Challenges of Circular RNAs
Li, X., Yang, L., & Chen, L.-L. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.06.034 · Cited by 2,062
CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model
Wang, L., Park, H. J., Dasari, S., Wang, S., Kocher, J.-P., & Li, W. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt006 · Cited by 1,995
Regulation of circRNA biogenesis
Chen, L.-L., & Yang, L. (2015) · RNA Biology · doi:10.1080/15476286.2015.1020271 · Cited by 1,953
circBase: a database for circular RNAs
Glažar, P., Papavasileiou, P., & Rajewsky, N. (2014) · RNA · doi:10.1261/rna.043687.113 · Cited by 1,933
Cited by
Closing the circle: current state and perspectives of circular RNA databases
Vromman, M., Vandesompele, J., & Volders, P.-J. (2021) · Briefings in Bioinformatics · doi:10.1093/bib/bbz175 · Cited by 111
Circular RNA as An Epigenetic Regulator in Chronic Liver Diseases
Zeng, X., Yuan, X., Cai, Q., Tang, C., & Gao, J. (2021) · Cells · doi:10.3390/cells10081945 · Cited by 55
Metadata
- Authors
- Liu, M., Wang, Q., Shen, J., Yang, B. B., & Ding, X.
- Venue
- RNA Biology
- Publisher
- Informa UK Limited
- Published
- 2019-04-25
- Volume
- 16
- Issue
- 7
- Pages
- 899-905
- ISSN
- 1547-6286 (ISSN-L)
- 1555-8584
- OpenAlex
- W2942409680
- Cited by
- 554
- References
- 40
- FWCI
- 15.90
- Type
- journal article
- Language
- en
- Open access
- bronze
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