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Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

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Multi-omics joint analysis reveals that the Miao medicine Yindanxinnaotong formula attenuates non-alcoholic fatty liver disease.

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Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1

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A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis

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Cell death regulation in myocardial toxicity induced by antineoplastic drugs

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TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production

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Cell Death in Liver Disease and Liver Surgery

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miR-146a-5p/TXNIP axis attenuates intestinal ischemia-reperfusion injury by inhibiting autophagy via the PRKAA/mTOR signaling pathway

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Autophagy, Ferroptosis, Apoptosis and Pyroptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease.

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Beyond Redox Regulation

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A structured biomimetic nanoparticle as inflammatory factor sponge and autophagy-regulatory agent against intervertebral disc degeneration and discogenic pain

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Stevia rebaudiana root polysaccharide modulates liver metabolism, bile acid, and gut microbiota improving HFD-induced NAFLD: Potential roles of ACSL1 and FADS2

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Contribution of Adiponectin/Carnitine Palmityl Transferase 1A‐Mediated Fatty Acid Metabolism during the Development of Idiopathic Pulmonary Fibrosis

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Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy

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TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease

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Dimeric guaianolide sesquiterpenoids from the flowers of Chrysanthemum indicum ameliorate hepatic steatosis through mitigating SIRT1-mediated lipid accumulation and ferroptosis

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Cytoskeleton alterations in non-alcoholic fatty liver disease

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Morroniside delays the progression of non-alcoholic steatohepatitis by promoting AMPK-mediated lipophagy

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Lipid Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Against Rubicon Ameliorates NAFLD by Modulating CD36 Along with Glycerophospholipid Metabolism

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Untargeted metabolomics reveals the role of AQP9 in nonalcoholic fatty liver disease in a mice model

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Melatonin alleviates palmitic acid-induced mitochondrial dysfunction by reducing oxidative stress and enhancing autophagy in bovine endometrial epithelial cells

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FOXO regulation of TXNIP induces ferroptosis in satellite cells by inhibiting glutathione metabolism, promoting Sarcopenia

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CKLF1 disrupts microglial efferocytosis following acute ischemic stroke by binding to phosphatidylserine

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Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways

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Salvianolic acid B inhibits autophagy and activation of hepatic stellate cells induced by TGF-β1 by downregulating the MAPK pathway

Jiang, N., Zhang, J., Jian, P., & Xu, L.-M. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.938856 · Cited by 18 · see citing works

Prophylactic effects of nutrition, dietary strategies, exercise, lifestyle and environment on nonalcoholic fatty liver disease

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Thiol-Based Antioxidants and the Epithelial/Mesenchymal Transition in Cancer

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The roles of autophagy and thyroid hormone in the pathogenesis and treatment of NAFLD

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Ischemic preconditioning attenuates endoplasmic reticulum stress-dependent apoptosis of hepatocytes by regulating autophagy in hepatic ischemia-reperfusion injury

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Tetrahydrocurcumin ameliorates hepatic steatosis by restoring hepatocytes lipophagy through mTORC1-TFEB pathway in nonalcoholic steatohepatitis

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Vitamin D supplementation ameliorates ductular reaction, liver inflammation and fibrosis in mice by upregulating TXNIP in ductular cells

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The lncRNA CASC9 alleviates lipopolysaccharide-induced acute kidney injury by regulating the miR-424-5p/TXNIP pathway

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microRNA-135a-5p regulates NOD-like receptor family pyrin domain containing 3 inflammasome-mediated hypertensive cardiac inflammation and fibrosis via thioredoxin-interacting protein

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Mechanisms of Xuefu Zhuyu Decoction in the treatment of coronary heart disease based on integrated metabolomics and network pharmacology approach.

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Vitamin D3 activates the innate immune response and xenophagy against Nocardia seriolae through the VD receptor in liver of largemouth bass (Micropterus salmoides)

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Cancer Cell Membrane-Coated Nanoparticles for Treatment of Oral Tongue Squamous Cell Carcinoma by Combining Photothermal/Photodynamic Therapy and Autophagy Inhibition

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PTBP1 knockdown impairs autophagy flux and inhibits gastric cancer progression through TXNIP-mediated oxidative stress

Wang, S., Wang, X., Qin, C., Liang, C., Li, W., Ran, A., Ma, Q., Pan, X., Yang, F., Ren, J., et al. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00626-1 · Cited by 16 · see citing works

Role of acyl-coenzyme A oxidase 1 (ACOX1) on palmitate-induced inflammation and ROS production of macrophages in large yellow croaker (Larimichthys crocea)

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Astragaloside I Promotes Lipophagy and Mitochondrial Biogenesis to Improve Hyperlipidemia by Regulating Akt/mTOR/TFEB Pathway

Zhao, J., Gao, G., Ding, J., Liu, W., Wang, T., Zhao, L., Xu, J., Zhang, Z., Zhang, X., & Xie, Z. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c03172 · Cited by 15 · see citing works

Shuangyu Tiaozhi decoction alleviates non-alcoholic fatty liver disease by improving lipid deposition, insulin resistance, and inflammation in vitro and in vivo

Yin, G.-L., Liang, H.-Y., Sun, W.-X., Zhang, S.-Z., Feng, Y.-N., Liang, P., Chen, S.-T., Liu, X., Pan, W., & Zhang, F.-X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1016745 · Cited by 14 · see citing works

Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis

Hou, L., Zhai, X., Zhang, Y., Xing, J., Li, C., Zhou, S., Zhu, X., & Zhang, B. (2024) · Liver International · doi:10.1111/liv.15915 · Cited by 15 · see citing works

Choline suppresses hepatocellular carcinoma progression by attenuating AMPK/mTOR-mediated autophagy via choline transporter SLC5A7 activation

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Si-Wu-Tang alleviates metabolic dysfunction-associated fatty liver disease by inhibiting ACSL4-mediated arachidonic acid metabolism and ferroptosis in MCD diet-fed mice

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Punicalagin Ameliorates Diabetic Liver Injury by Inhibiting Pyroptosis and Promoting Autophagy via Modulation of the FoxO1/TXNIP Signaling Pathway

Tan, X., Yi, L., Zhang, R., Zhang, Y., You, Z., & Yang, L. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202300912 · Cited by 15 · see citing works

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Ma, J., Xie, N., Wang, Z., Liang, X., Han, Y., Zhao, Q., Wang, M., Lu, H., Kou, W., Alazawi, W., et al. (2026) · Advanced Science · doi:10.1002/advs.202519109 · Cited by 14 · see citing works

The relationship between increased levels of microbiota-derived lipopolysaccharide in obesity and the pathophysiology of neurodegenerative diseases

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Ubiquitin-specific peptidase 25 exacerbated osteoarthritis progression through facilitating TXNIP ubiquitination and NLRP3 inflammasome activation

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Targeting DGAT1 inhibits prostate cancer cells growth by inducing autophagy flux blockage via oxidative stress

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Morroniside Ameliorates High-Fat and High-Fructose-Driven Chronic Kidney Disease by Motivating AMPK–TFEB Signal Activation to Accelerate Lipophagy and Inhibiting Inflammatory Response

Zhang, C., Xiong, Y., Luo, Y., Liu, K., Tong, Q., Song, Y., & Qiu, Z. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c07684 · Cited by 13 · see citing works

Time-restricted feeding improves metabolic and endocrine profiles in mice with polycystic ovary syndrome

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Artesunate Inhibits Lipid Accumulation and Inflammation by Regulating the NLRP3 Inflammasome in Nonalcoholic Fatty Liver Disease

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Diosgenin attenuates nonalcoholic fatty liver disease through mTOR-mediated inhibition of lipid accumulation and inflammation

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Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes

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USP10 Alleviates Palmitic Acid-induced Steatosis through Autophagy in HepG2 Cells

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Syringin alleviates hepatic fibrosis by enhancing autophagic flux and attenuating ER stress-TRIB3/SMAD3 in diabetic mice

Deng, Z., Ren, C., Tang, C., Chen, S., Li, J., Wei, J., Zhang, Q., & Ma, B. (2023) · Tissue and Cell · doi:10.1016/j.tice.2023.102159 · Cited by 12 · see citing works

Hepatocyte HIF-2α aggravates NAFLD by inducing ferroptosis through increasing extracellular iron

Luo, S., Lu, Z., Wang, L., Li, Y., Zeng, Y., & Lu, H. (2024) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00287.2023 · Cited by 12 · see citing works

Dapagliflozin attenuates diabetes-induced podocyte lipotoxicity via ERRα-Mediated lipid metabolism

Hu, H., Wang, J., Peng, Z., Fan, Y., Yang, Q., & Hu, J. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.04.028 · Cited by 12 · see citing works

Lp-PLA2 silencing ameliorates inflammation and autophagy in nonalcoholic steatohepatitis through inhibiting the JAK2/STAT3 pathway

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Pin1 Exacerbates Non-Alcoholic Fatty Liver Disease by Enhancing Its Activity through Binding to ACC1

Jin, Y., Shangguan, Z., Pang, J., Chen, Y., Lin, S., & Liu, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115822 · Cited by 11 · see citing works

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Yu, Y., Feng, M., Chen, Y., Jia, H., Zhang, Q., Tong, M., Li, Y.-M., Zhao, Y. C., Liu, X., Cao, S., et al. (2025) · Advanced Science · doi:10.1002/advs.202415846 · Cited by 11 · see citing works

NIR Driven Pd/Cerium Oxide Nano‐Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy

Qin, T., Qin, L., Zhao, Y., Chen, Y., Liu, Q., Lin, X., Lan, Y., Huang, Y., Liu, Y., Zhang, K., et al. (2025) · Advanced Science · doi:10.1002/advs.202417252 · Cited by 11 · see citing works

Sirtuins and autophagy in lipid metabolism

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Oleic and linoleic acids promote chondrocyte apoptosis by inhibiting autophagy via downregulation of SIRT1/FOXO1 signaling

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Flavonoids from Rhododendron nivale Hook. f ameliorate alcohol-associated liver disease via activating the PPARα signaling pathway

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Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction‑associated fatty liver disease

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Increased plasma genistein after bariatric surgery could promote remission of NAFLD in patients with obesity

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Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure

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Inhibition of ? 24-dehydrocholesterol reductase ameliorates non-alcoholic steatohepatitis in mice

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Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis

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Hepatic autophagy fluctuates during the development of non-alcoholic fatty liver disease

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