TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation

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TXNIP Suppresses the Osteochondrogenic Switch of Vascular Smooth Muscle Cells in Atherosclerosis

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Evidence for Lysosomal Dysfunction within the Epidermis in Psoriasis and Atopic Dermatitis

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Sulfide regulation and catabolism in health and disease

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Anthelmintics nitazoxanide protects against experimental hyperlipidemia and hepatic steatosis in hamsters and mice

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Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway

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Thioredoxin-Interacting Protein in Cancer and Diabetes

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The Role of Autophagy and Pyroptosis in Liver Disorders

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From Metabolic Syndrome to Neurological Diseases: Role of Autophagy

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Aurantio-Obtusin Attenuates Non-Alcoholic Fatty Liver Disease Through AMPK-Mediated Autophagy and Fatty Acid Oxidation Pathways

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Aucubin ameliorates liver fibrosis and hepatic stellate cells activation in diabetic mice via inhibiting ER stress-mediated IRE1α/TXNIP/NLRP3 inflammasome through NOX4/ROS pathway

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The monomer TEC of blueberry improves NASH by augmenting tRF-47-mediated autophagy/pyroptosis signaling pathway

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Supplementation of Lycium barbarum Polysaccharide Combined with Aerobic Exercise Ameliorates High-Fat-Induced Nonalcoholic Steatohepatitis via AMPK/PPARα/PGC-1α Pathway

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Oleic acid improves hepatic lipotoxicity injury by alleviating autophagy dysfunction

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CCAAT/Enhancer-Binding Proteins in Fibrosis: Complex Roles Beyond Conventional Understanding

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Nuclear miR-204-3p mitigates metabolic dysfunction-associated steatotic liver disease in mice

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Research progress on AMPK in the pathogenesis and treatment of MASLD

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Intracellular C3 prevents hepatic steatosis by promoting autophagy and very‐low‐density lipoprotein secretion

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Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

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Multi-omics joint analysis reveals that the Miao medicine Yindanxinnaotong formula attenuates non-alcoholic fatty liver disease.

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Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1

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A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis

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TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production

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Cell Death in Liver Disease and Liver Surgery

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Autophagy, Ferroptosis, Apoptosis and Pyroptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease.

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Beyond Redox Regulation

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A structured biomimetic nanoparticle as inflammatory factor sponge and autophagy-regulatory agent against intervertebral disc degeneration and discogenic pain

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Stevia rebaudiana root polysaccharide modulates liver metabolism, bile acid, and gut microbiota improving HFD-induced NAFLD: Potential roles of ACSL1 and FADS2

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Contribution of Adiponectin/Carnitine Palmityl Transferase 1A‐Mediated Fatty Acid Metabolism during the Development of Idiopathic Pulmonary Fibrosis

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Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy

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TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease

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Dimeric guaianolide sesquiterpenoids from the flowers of Chrysanthemum indicum ameliorate hepatic steatosis through mitigating SIRT1-mediated lipid accumulation and ferroptosis

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Cytoskeleton alterations in non-alcoholic fatty liver disease

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Morroniside delays the progression of non-alcoholic steatohepatitis by promoting AMPK-mediated lipophagy

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Lipid Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Against Rubicon Ameliorates NAFLD by Modulating CD36 Along with Glycerophospholipid Metabolism

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Untargeted metabolomics reveals the role of AQP9 in nonalcoholic fatty liver disease in a mice model

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Melatonin alleviates palmitic acid-induced mitochondrial dysfunction by reducing oxidative stress and enhancing autophagy in bovine endometrial epithelial cells

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FOXO regulation of TXNIP induces ferroptosis in satellite cells by inhibiting glutathione metabolism, promoting Sarcopenia

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CKLF1 disrupts microglial efferocytosis following acute ischemic stroke by binding to phosphatidylserine

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Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways

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Salvianolic acid B inhibits autophagy and activation of hepatic stellate cells induced by TGF-β1 by downregulating the MAPK pathway

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Prophylactic effects of nutrition, dietary strategies, exercise, lifestyle and environment on nonalcoholic fatty liver disease

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Thiol-Based Antioxidants and the Epithelial/Mesenchymal Transition in Cancer

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The roles of autophagy and thyroid hormone in the pathogenesis and treatment of NAFLD

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Ischemic preconditioning attenuates endoplasmic reticulum stress-dependent apoptosis of hepatocytes by regulating autophagy in hepatic ischemia-reperfusion injury

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Tetrahydrocurcumin ameliorates hepatic steatosis by restoring hepatocytes lipophagy through mTORC1-TFEB pathway in nonalcoholic steatohepatitis

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Vitamin D supplementation ameliorates ductular reaction, liver inflammation and fibrosis in mice by upregulating TXNIP in ductular cells

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The lncRNA CASC9 alleviates lipopolysaccharide-induced acute kidney injury by regulating the miR-424-5p/TXNIP pathway

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microRNA-135a-5p regulates NOD-like receptor family pyrin domain containing 3 inflammasome-mediated hypertensive cardiac inflammation and fibrosis via thioredoxin-interacting protein

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Mechanisms of Xuefu Zhuyu Decoction in the treatment of coronary heart disease based on integrated metabolomics and network pharmacology approach.

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Vitamin D3 activates the innate immune response and xenophagy against Nocardia seriolae through the VD receptor in liver of largemouth bass (Micropterus salmoides)

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Cancer Cell Membrane-Coated Nanoparticles for Treatment of Oral Tongue Squamous Cell Carcinoma by Combining Photothermal/Photodynamic Therapy and Autophagy Inhibition

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PTBP1 knockdown impairs autophagy flux and inhibits gastric cancer progression through TXNIP-mediated oxidative stress

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Role of acyl-coenzyme A oxidase 1 (ACOX1) on palmitate-induced inflammation and ROS production of macrophages in large yellow croaker (Larimichthys crocea)

Kong, A., Xu, D., Hao, T., Liu, Q., Zhan, R., Mai, K., & Ai, Q. (2022) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2022.104501 · Cited by 18

Astragaloside I Promotes Lipophagy and Mitochondrial Biogenesis to Improve Hyperlipidemia by Regulating Akt/mTOR/TFEB Pathway

Zhao, J., Gao, G., Ding, J., Liu, W., Wang, T., Zhao, L., Xu, J., Zhang, Z., Zhang, X., & Xie, Z. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c03172 · Cited by 15

Shuangyu Tiaozhi decoction alleviates non-alcoholic fatty liver disease by improving lipid deposition, insulin resistance, and inflammation in vitro and in vivo

Yin, G.-L., Liang, H.-Y., Sun, W.-X., Zhang, S.-Z., Feng, Y.-N., Liang, P., Chen, S.-T., Liu, X., Pan, W., & Zhang, F.-X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1016745 · Cited by 14

Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis

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Choline suppresses hepatocellular carcinoma progression by attenuating AMPK/mTOR-mediated autophagy via choline transporter SLC5A7 activation

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Punicalagin Ameliorates Diabetic Liver Injury by Inhibiting Pyroptosis and Promoting Autophagy via Modulation of the FoxO1/TXNIP Signaling Pathway

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Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

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The relationship between increased levels of microbiota-derived lipopolysaccharide in obesity and the pathophysiology of neurodegenerative diseases

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Targeting DGAT1 inhibits prostate cancer cells growth by inducing autophagy flux blockage via oxidative stress

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Morroniside Ameliorates High-Fat and High-Fructose-Driven Chronic Kidney Disease by Motivating AMPK–TFEB Signal Activation to Accelerate Lipophagy and Inhibiting Inflammatory Response

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Time-restricted feeding improves metabolic and endocrine profiles in mice with polycystic ovary syndrome

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Artesunate Inhibits Lipid Accumulation and Inflammation by Regulating the NLRP3 Inflammasome in Nonalcoholic Fatty Liver Disease

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Diosgenin attenuates nonalcoholic fatty liver disease through mTOR-mediated inhibition of lipid accumulation and inflammation

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Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes

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USP10 Alleviates Palmitic Acid-induced Steatosis through Autophagy in HepG2 Cells

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Syringin alleviates hepatic fibrosis by enhancing autophagic flux and attenuating ER stress-TRIB3/SMAD3 in diabetic mice

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Hepatocyte HIF-2α aggravates NAFLD by inducing ferroptosis through increasing extracellular iron

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Dapagliflozin attenuates diabetes-induced podocyte lipotoxicity via ERRα-Mediated lipid metabolism

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Lp-PLA2 silencing ameliorates inflammation and autophagy in nonalcoholic steatohepatitis through inhibiting the JAK2/STAT3 pathway

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Pin1 Exacerbates Non-Alcoholic Fatty Liver Disease by Enhancing Its Activity through Binding to ACC1

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Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

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NIR Driven Pd/Cerium Oxide Nano‐Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy

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Oleic and linoleic acids promote chondrocyte apoptosis by inhibiting autophagy via downregulation of SIRT1/FOXO1 signaling

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Flavonoids from Rhododendron nivale Hook. f ameliorate alcohol-associated liver disease via activating the PPARα signaling pathway

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Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction‑associated fatty liver disease

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Increased plasma genistein after bariatric surgery could promote remission of NAFLD in patients with obesity

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Inhibition of ? 24-dehydrocholesterol reductase ameliorates non-alcoholic steatohepatitis in mice

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Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis

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Reduced Lysosomal Acidification Induce p53 and Unfolded Protein Response in Mice With Nutritional Steatohepatitis

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