Gao, Bin

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

Gao, B., & Bataller, R. (2011) · Gastroenterology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 1,963

Alcoholic liver disease

Seitz, H. K., Bataller, R., Cortez-Pinto, H., Gao, B., Gual, A., Lackner, C., Mathurin, P., Mueller, S., Szabo, G., & Tsukamoto, H. (2018) · Nature Reviews Disease Primers

Alcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment

Cited by 1,271

Liver: An organ with predominant innate immunity

Gao, B., Jeong, W.-I., & Tian, Z. (2008) · Hepatology

Liver physiology and pathologyImmune Response and Inflammation

Cited by 952

Natural Killer Cells Ameliorate Liver Fibrosis by Killing Activated Stellate Cells in NKG2D-Dependent and Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Dependent Manners

Radaeva, S., Sun, R., Jaruga, B., Nguyen, V. T., Tian, Z., & Gao, B. (2006) · Gastroenterology

Liver physiology and pathologyImmune Cell Function and Interaction

Cited by 610

Hepatocytes: a key cell type for innate immunity

Zhou, Z., Xu, M.-J., & Gao, B. (2016) · Cellular & Molecular Immunology

Immune Response and InflammationLiver physiology and pathology

Cited by 472

Endoplasmic Reticulum Stress Causes Liver Cancer Cells to Release Exosomal miR‐23a‐3p and Up‐regulate Programmed Death Ligand 1 Expression in Macrophages

Liu, J., Fan, L., Yu, H., Zhang, J., He, Y., Feng, D., Wang, F., Li, X., Liu, Q., Li, Y., et al. (2019) · Hepatology

Extracellular vesicles in diseaseCancer Immunotherapy and Biomarkers

Cited by 449

Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice

Kong, X., Feng, D., Wang, H., Hong, F., Bertola, A., Wang, F.-S., & Gao, B. (2012) · Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 448

Inflammatory pathways in alcoholic steatohepatitis

Gao, B., Ahmad, M. F., Nagy, L. E., & Tsukamoto, H. (2019) · Journal of Hepatology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 392

Alcohol-associated liver disease

Mackowiak, B., Fu, Y., Maccioni, L., & Gao, B. (2024) · Journal of Clinical Investigation

Alcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment

Cited by 359

Molecular Mechanisms of Alcoholic Fatty Liver

Purohit, V., Gao, B., & Song, B. (2009) · Alcoholism: Clinical and Experimental Research

Alcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment

Cited by 312

Myeloid‐Cell–Specific IL‐6 Signaling Promotes MicroRNA‐223‐Enriched Exosome Production to Attenuate NAFLD‐Associated Fibrosis

Hou, X., Yin, S., Ren, R., Liu, S., Yong, L., Liu, Y., Li, Y., Zheng, M., Kunos, G., Gao, B., et al. (2021) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 223

TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation

Park, H.-S., Song, J.-W., Park, J.-H., Lim, B.-K., Moon, O.-S., Son, H.-Y., Lee, J.-H., Gao, B., Won, Y.-S., & Kwon, H.-J. (2021) · Autophagy

Liver Disease Diagnosis and TreatmentAutophagy in Disease and Therapy

Cited by 219

ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles

Seo, W., Gao, Y., He, Y., Sun, J., Xu, H., Feng, D., Park, S. H., Cho, Y.-E., Guillot, A., Ren, T., et al. (2019) · Journal of Hepatology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 218

IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease

Ma, H.-Y., Yamamoto, G., Xu, J., Liu, X., Karin, D., Kim, J. Y., Alexandrov, L. B., Koyama, Y., Nishio, T., Benner, C., et al. (2020) · Journal of Hepatology

Liver physiology and pathologyHepatocellular Carcinoma Treatment and Prognosis

Cited by 216

Aldehyde Dehydrogenase 2 Deficiency Ameliorates Alcoholic Fatty Liver but Worsens Liver Inflammation and Fibrosis in Mice

Kwon, H.-J., Won, Y.-S., Park, O., Chang, B., Duryee, M. J., Thiele, G. E., Matsumoto, A., Singh, S., Abdelmegeed, M. A., Song, B.-J., et al. (2014) · Hepatology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 191

Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride #

Park, O., Jeong, W.-I., Wang, L., Wang, H., Lian, Z.-X., Gershwin, E. M., & Gao, B. (2009) · Hepatology

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 189

Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice

Xiang, X., Feng, D., Hwang, S., Ren, T., Wang, X., Trojnar, E., Matyas, C., Mo, R., Shang, D., He, Y., et al. (2020) · Journal of Hepatology

Liver physiology and pathologyLiver Disease and Transplantation

Cited by 189

Elevated interleukin-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol-induced apoptosis in the liver: involvement of induction of Bcl-2 and Bcl-xL proteins

Hong, F., Kim, W.-H., Tian, Z., Jaruga, B., Ishac, E., Shen, X., & Gao, B. (2002) · Oncogene

Alcohol Consumption and Health EffectsCell death mechanisms and regulation

Cited by 179

Neutrophil-Hepatic Stellate Cell Interactions Promote Fibrosis in Experimental Steatohepatitis

Zhou, Z., Xu, M.-J., Cai, Y., Wang, W., Jiang, J. X., Varga, Z. V., Feng, D., Pacher, P., Kunos, G., Torok, N. J., et al. (2018) · Cellular and Molecular Gastroenterology and Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 164

Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery

Moh, A., Iwamoto, Y., Chai, G.-X., Zhang, S. S.-M., Kano, A., Yang, D. D., Zhang, W., Wang, J., Jacoby, J. J., Gao, B., et al. (2007) · Laboratory Investigation

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 147

Suppression of innate immunity (natural killer cell/interferon-γ) in the advanced stages of liver fibrosis in mice

Jeong, W.-I., Park, O., Suh, Y.-G., Byun, J.-S., Park, S.-Y., Choi, E., Kim, J.-K., Ko, H., Wang, H., Miller, A. M., et al. (2011) · Hepatology

Liver physiology and pathologyImmune Cell Function and Interaction

Cited by 142

Retinoic Acid Signaling Sensitizes Hepatic Stellate Cells to NK Cell Killing via Upregulation of NK Cell Activating Ligand RAE1

Radaeva, S., Wang, L., Radaev, S., Jeong, W.-I., Park, O., & Gao, B. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Liver physiology and pathologyImmune Cell Function and Interaction

Cited by 123

Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression

Guillot, A., Winkler, M., Silva Afonso, M., Aggarwal, A., Lopez, D., Berger, H., Kohlhepp, M. S., Liu, H., Özdirik, B., Eschrich, J., et al. (2023) · Hepatology

Liver Diseases and ImmunityLiver Disease Diagnosis and Treatment

Cited by 116

Alcoholic hepatitis: Translational approaches to develop targeted therapies

Mandrekar, P., Bataller, R., Tsukamoto, H., & Gao, B. (2016) · Hepatology

Alcohol Consumption and Health EffectsLiver Disease and Transplantation

Cited by 115