An initial proof of concept: a replicated single-case study of a CBT group treatment with partner involvement for vulvodynia
Open accessAbstract
Vulvodynia is common and has an immense impact on affected women and their partners. Psychological factors have been found to contribute to pain maintenance and exacerbation, and treatments addressing psychological factors have yielded positive results. This study employed a replicated single-case experimental design to examine a cognitive behavioral therapy (CBT) group treatment with partner involvement in vulvodynia. Repeated measures of pain intensity related to pain-inflicting behaviors were collected weekly throughout baseline and treatment phases. Associated outcomes were measured pre-, post- and at two follow-up assessments. Participants were 18-45-year-old women, in a stable sexual relationship with a man, experiencing vulvodynia. Five women completed the treatment consisting of 10 group sessions and 3 couple sessions. Data were analyzed through visual inspection and supplementary nonparametric calculations. The study showed promising results of the CBT treatment in alleviating pain intensity in connection to specific pain-inflicting behavior since three out of five participants showed improvements. For the participants who improved, sexual function, pain catastrophizing, avoidance, and endurance behavior changed during treatment and were maintained at follow-ups. These results warrant further study of the CBT treatment, in larger, and controlled formats.
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Psychological treatments based on cognitive behavioral therapy and acceptance-based treatments for vulvar pain and sexual function have proved beneficial.
“Psychological treatments based on cognitive behavioral therapy and acceptance-based treatments for vulvar pain and sexual function have proved beneficial. 11-13”
From Internet-based treatment for provoked vulvodynia: Factors associated with treatment outcomes (2025) · cites this paper as [11]
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
Rosen, C. B. (2000) · Journal of Sex & Marital Therapy · doi:10.1080/009262300278597 · Cited by 6,593 · see citing works
Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
Vlaeyen, J. W. S., & Linton, S. J. (2000) · Pain · doi:10.1016/s0304-3959(99)00242-0 · Cited by 4,931 · see citing works
Self-citationLecrubier, Y., Sheehan, D., Weiller, E., Amorim, P., Bonora, I., Sheehan, K. H., Janavs, J., & Dunbar, G. (1997) · European Psychiatry · doi:10.1016/s0924-9338(97)83296-8 · Cited by 3,513 · see citing works
Single-case research designs: Methods for clinical and applied settings
Hayes, S. C. (1983) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(83)90018-6 · Cited by 2,677 · see citing works
The female sexual function index (FSFI): cross-validation and development of clinical cutoff scores
WIEGEL, M., MESTON, C., & ROSEN, R. (2005) · Journal of Sex & Marital Therapy · doi:10.1080/00926230590475206 · Cited by 2,396 · see citing works
Combining nonoverlap and trend for single-case research: Tau-U
Parker, R. I., Vannest, K. J., Davis, J. L., & Sauber, S. B. (2011) · Behavior Therapy · doi:10.1016/j.beth.2010.08.006 · Cited by 1,468 · see citing works
Single case experimental designs: Strategieṡ for studying behavior change
Matson, J. L. (1985) · Applied Research in Mental Retardation · doi:10.1016/0270-3092(85)90012-8 · Cited by 1,193 · see citing works
An improved effect size for single-case research: nonoverlap of all pairs.
Parker, R. I., & Vannest, K. (2009) · Behavior Therapy · doi:10.1016/j.beth.2008.10.006 · Cited by 1,126 · see citing works
Negative effects from psychological treatments: a perspective
Barlow, D. H. (2010) · American Psychologist · doi:10.1037/a0015643 · Cited by 426 · see citing works
Harlow, B. L., Kunitz, C. G., Nguyen, R. H. N., Rydell, S. A., Turner, R. M., & MacLehose, R. F. (2014) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2013.09.033 · Cited by 322 · see citing works
Haefner, H. K., Collins, M. E., Davis, G. D., Edwards, L., Foster, D. C., Hartmann, E., Kaufman, R. H., Lynch, P., Margesson, L. J., Moyal‐Barracco, M., et al. (2005) · Journal of Lower Genital Tract Disease · doi:10.1097/00128360-200501000-00009 · Cited by 321 · see citing works
Prevalence and demographic characteristics of vulvodynia in a population-based sample
Reed, B. D., Harlow, S. D., Sen, A., Legocki, L. J., Edwards, R. M., Arato, N., & Haefner, H. K. (2012) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2011.08.012 · Cited by 317 · see citing works
Vulvodynia: Assessment and Treatment
Goldstein, A. T., Pukall, C. F., Brown, C., Bergeron, S., Stein, A., & Kellogg-Spadt, S. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.01.020 · Cited by 292 · see citing works
Bornstein, J., Goldstein, A. T., Stockdale, C. K., Bergeron, S., Pukall, C., Zolnoun, D., Coady, D., & International Society for the Study of Vulvovaginal Disease (ISSVD) (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.02.167 · Cited by 260 · see citing works
Interpreting Kendall’s Tau and Tau- <i>U</i> for single-case experimental designs
Brossart, D. F., Laird, V. C., & Armstrong, T. W. (2018) · Cogent Psychology · doi:10.1080/23311908.2018.1518687 · Cited by 210 · see citing works
van Lankveld, J. J. D. M., Granot, M., Schultz, W. C. M. W., Binik, Y. M., Wesselmann, U., Pukall, C. F., Bohm‐Starke, N., & Achtari, C. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01631.x · Cited by 205 · see citing works
Desrochers, G., Bergeron, S., Khalifé, S., Dupuis, M.-J., & Jodoin, M. (2009) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e31819976e3 · Cited by 199 · see citing works
Do Psychosexual Factors Play a Role in the Etiology of Provoked Vestibulodynia? A Critical Review
Desrochers, G., Bergeron, S., Landry, T., & Jodoin, M. (2008) · Journal of Sex & Marital Therapy · doi:10.1080/00926230701866083 · Cited by 185 · see citing works
Danielsson, I., Sjöberg, I., Stenlund, H. C., & Wikman, M. (2003) · Scandinavian Journal of Public Health · doi:10.1080/14034940210134040 · Cited by 161 · see citing works
Elmerstig, E., Wijma, B. E., & Swahnberg, K. (2013) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.3109/0167482x.2013.793665 · Cited by 103 · see citing works
Female Sexual Pain Disorders: a Review of the Literature on Etiology and Treatment
Bergeron, S., Corsini‐Munt, S., Aerts, L., Rancourt, K. M., & Rosen, N. O. (2015) · Current Sexual Health Reports · doi:10.1007/s11930-015-0053-y · Cited by 102 · see citing works
Predictors of Task-Persistent and Fear-Avoiding Behaviors in Women with Sexual Pain Disorders
Brauer, M., Lakeman, M. M. E., van Lunsen, R. H. W., & Laan, E. T. M. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12697 · Cited by 90 · see citing works
Klaassen, M., & ter Kuile, M. M. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01217.x · Cited by 85 · see citing works
Treatment of vulvodynia: pharmacological and non-pharmacological approaches
Rosen, N. O., Dawson, S. J., Brooks, M., & Kellogg-Spadt, S. (2019) · Drugs · doi:10.1007/s40265-019-01085-1 · Cited by 83 · cited 2× · see citing works
“Beyond apparent limitations when comparing results of group designs and single-case designs, the results could be considered to be in agreement with earlier studies investigating the effect of CBT on PVD (see, e.g. Rosen et al., 2019).”
BackgroundResultBiopsychosocial Factors Associated with Dyspareunia in a Community Sample of Adolescent Girls
Landry, T., & Bergeron, S. (2010) · Archives of Sexual Behavior · doi:10.1007/s10508-010-9637-9 · Cited by 81 · see citing works
ter Kuile, M. M., & Weijenborg, P. T. M. (2006) · Journal of Sex & Marital Therapy · doi:10.1080/00926230600575306 · Cited by 79 · see citing works
Cognitive-Affective Correlates and Predictors of Superficial Dyspareunia
Brauer, M., ter Kuile, M. M., Laan, E. T. M., & Trimbos, B. J. B. M. Z. (2008) · Journal of Sex & Marital Therapy · doi:10.1080/00926230802525604 · Cited by 72 · see citing works
Single-case Methods in Clinical Psychology: A practical guide
Limond, J. (2018) · Clinical Psychology Forum · doi:10.53841/bpscpf.2018.1.310.50 · Cited by 70 · see citing works
A Psychological View of Sexual Pain among Women: Applying the Fear-Avoidance Model
Thomtén, J., & Linton, S. J. (2013) · Women s Health · doi:10.2217/whe.13.19 · Cited by 69 · see citing works
Self-citationBrotto, L. A., Bergeron, S., Zdaniuk, B., & Basson, R. (2020) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000473 · Cited by 59 · see citing works
A Priori Justification for Effect Measures in Single-Case Experimental Designs
Manolov, R., Moeyaert, M., & Fingerhut, J. E. (2022) · Perspectives on Behavior Science · doi:10.1007/s40614-021-00282-2 · Cited by 53 · see citing works
Treatment of provoked vulvodynia: a systematic review
Bohm-Starke, N., Ramsay, K. W., Lytsy, P., Nordgren, B., Sjöberg, I., Moberg, K., & Flink, I. (2022) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2022.02.008 · Cited by 51 · see citing works
Self-citationBergeron, S., Vaillancourt‐Morel, M., Corsini‐Munt, S., Steben, M., Delisle, I., Mayrand, M., & Rosen, N. O. (2021) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000631 · Cited by 45 · see citing works
Ryding, E. L., & Blom, C. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12778 · Cited by 40 · see citing works
Corsini‐Munt, S., Rancourt, K. M., Dubé, J. P., Rossi, M. A., & Rosen, N. O. (2017) · Journal of Pain Research · doi:10.2147/jpr.s126259 · Cited by 33 · see citing works
Introduction to the Special Issue on Single-Case Systematic Reviews and Meta-Analyses
Maggin, D. M., Lane, K. L., & Pustejovsky, J. E. (2017) · Remedial and Special Education · doi:10.1177/0741932517717043 · Cited by 24 · see citing works
Coping with painful sex: Development and initial validation of the CHAMP Sexual Pain Coping Scale
Flink, I. K., Thomtén, J., Engman, L., Hedström, S., & Linton, S. J. (2015) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2015.05.002 · Cited by 17 · see citing works
Self-citationEngman, L., Flink, I. K., Ekdahl, J., Boersma, K., & Linton, S. J. (2018) · European Journal of Pain · doi:10.1002/ejp.1227 · Cited by 13 · see citing works
Self-citationNon-Medical, Medical, and Surgical Approaches for the Treatment of Provoked Vestibulodynia
Pukall, C. F., Mitchell, L. S., & Goldstein, A. T. (2016) · Current Sexual Health Reports · doi:10.1007/s11930-016-0093-y · Cited by 12 · see citing works
Couple Sex Therapy Versus Group Therapy for Women with Genito-pelvic Pain
Bergeron, S., Merwin, K. E., Dubé, J. P., & Rosen, N. O. (2018) · Current Sexual Health Reports · doi:10.1007/s11930-018-0154-5 · Cited by 9 · see citing works
The role of catastrophizing in vulvovaginal pain: Impact on pain and partner responses over time
Flink, I. K., Engman, L., Thomtén, J., & Linton, S. J. (2017) · Journal of Applied Biobehavioral Research · doi:10.1111/jabr.12093 · Cited by 4 · see citing works
Self-citation
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Myrtveit‐Stensrud, L., Haugstad, G. K., Rème, S. E., Schaller, S., & Groven, K. S. (2023) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.14537 · Cited by 17 · see citing works
A scoping review of vulvodynia research: Diagnosis, treatment, and care experiences
Lountzi, A. Z., Abhyankar, P., & Durand, H. (2025) · Women s Health · doi:10.1177/17455057251345946 · Cited by 11 · see citing works
Considerations for idiographic chronic pain treatment
Lavefjord, A., & Sundström, F. (2024) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2024.101946 · Cited by 8 · see citing works
Sharaa, H. A., Bartels, S. L., Taygar, A. S., Engman, L., Petersson, S., Flink, I. K., Boersma, K., McCracken, L. M., Simons, L. E., Vlaeyen, J. W. S., et al. (2025) · European Journal of Pain · doi:10.1002/ejp.70128 · Cited by 6 · see citing works
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Schemer, L., Glogan, E., Sjouwerman, R., Ahm, R., Ashar, Y. K., Boddez, Y., Boersma, K., Cañeiro, J. P., Cima, R. F. F., den Hollander, M., et al. (2026) · Behaviour Research and Therapy · doi:10.1016/j.brat.2026.104998 · Cited by 3 · see citing works
Self-citationLogan, G. S., Gustafson, D. L., Swab, M., Rains, A., Miller, M., Jackman, V., & Bajzak, K. I. (2024) · The Journal of Sexual Medicine · doi:10.1093/jsxmed/qdae163 · Cited by 2 · see citing works
Pukall, C. F., Hellberg, C., Österberg, M., Jonsson, A. K., Kempe, S., Gustavsson, P. J., & Bohm‐Starke, N. (2025) · The Journal of Sexual Medicine · doi:10.1093/jsxmed/qdaf120 · Cited by 2 · see citing works
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- Authors
- Engman, L., Ter Kuile, M. M., Linton, S. J., Ekholm, E., Tuijnman-Raasveld, C. C., & Flink, I. K.
- Affiliations
- Örebro University (SE)
- Department of Obstetrics and Gynaecology, Leiden University Medical Center, Leiden, The Netherlands
- Corresponding author
- Engman, Linnéa
- ORCID
- Venue
- Cognitive Behaviour Therapy
- Publisher
- Informa UK Limited
- Published
- 2022-08-12
- Volume
- 51
- Issue
- 6
- Pages
- 503-519
- ISSN
- 1650-6073 (ISSN-L)
- 1651-2316
- OpenAlex
- W4290878489
- Cited by
- 9
- References
- 42
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 3 · 2023: 1
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Cognitive Behaviour Therapy (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- vulvodynia, cognitive behavioral therapy, group therapy, partner involvement, couple therapy, pain intensity, pain catastrophizing, sexual function, avoidance behavior, psychological factors in pain
- MeSH terms
- Adolescent, Adult, Female, Humans, Male, Middle Aged, Pain, Surveys and Questionnaires, Sexual Behavior, Cognitive Behavioral Therapy, Young Adult, Vulvodynia, Catastrophization
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