A prospective registry evaluating the epidemiology and clinical care of traumatic brain injury patients presenting to a regional referral hospital in Moshi, Tanzania: challenges and the way forward
Abstract
Traumatic brain injury (TBI) is the most common cause of death and disability globally disproportionately affecting low- and middle-income countries where increasing injury rates are compounded by limited quality care. The objective of this study is to describe quality of care for TBI patients who presented to Kilimanjaro Christian Medical Center, Moshi, Tanzania. We evaluated a prospective quality improvement TBI registry that enrolled consecutive patients with acute TBI. Descriptive statistics and qualitative comparative analysis was performed. Overall, 893 TBI patients were enrolled during the study period, with a mean age of 32.1 years and who were mostly (80%) male. 12.9% suffered severe TBI (GCS < 9). Most injuries were road traffic (66%) especially motorcyclists (49%) and 26.8% were alcohol related. One intubation occurred, and 22.9% of hypoxic patients received oxygen. Severe TBI mortality was 47%. TBI affects men 15-45 years old in traffic crashes with high mortality for severe TBI (47%) patients. Care addressing secondary injury, hypoxemia, and hypotension is limited.
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Of adult injury patients who seek care in the KCMC ED, about 30% have a positive alcohol status upon arrival.
“Of the adult injury patients who seek care in the KCMC ED, about 30% have a positive alcohol status upon arrival [40].”
The study demographic is expected based on prior studies.
“The study demographic is expected based on prior studies [40,42].”
Cites
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The impact of alcohol among injury patients in Moshi, Tanzania: a nested case-crossover study
Staton, C. A., Vissoci, J. R. N., Toomey, N., Abdelgadir, J., Chou, P., Haglund, M., Mmbaga, B. T., Mvungi, M., & Swahn, M. (2018) · BMC Public Health · doi:10.1186/s12889-018-5144-z · Cited by 63 · see citing works
Self-citationVissoci, J. R. N., Hertz, J., El-Gabri, D., Andrade Do Nascimento, J. R., Pestillo De Oliveira, L., Mmbaga, B. T., Mvungi, M., & Staton, C. A. (2018) · Alcohol and Alcoholism · doi:10.1093/alcalc/agx058 · Cited by 40 · see citing works
Self-citationPerceptions of alcohol use among injury patients and their family members in Tanzanian society
Meier, B. J., El-Gabri, D., Friedman, K., Mvungi, M., Mmbaga, B. T., Nickenig Vissoci, J. R., & Staton, C. A. (2020) · Alcohol · doi:10.1016/j.alcohol.2019.06.001 · Cited by 21 · see citing works
Self-citationStaton, C. A., Vissoci, J. R. N., Wojcik, R., Hirshon, J. M., Mvungi, M., Mmbaga, B. T., & Swahn, M. (2018) · Alcohol · doi:10.1016/j.alcohol.2018.01.003 · Cited by 22 · see citing works
Self-citationStaton, C. A., Friedman, K., Phillips, A. J., Minnig, M. C., Sakita, F. M., Ngowi, K. M., Suffoletto, B., Hirshon, J. M., Swahn, M., Mmbaga, B. T., et al. (2023) · PLOS ONE · doi:10.1371/journal.pone.0288458 · Cited by 14 · see citing works
Self-citationZimmerman, A., Barcenas, L. K., Pesambili, M., Sakita, F., Mallya, S., Vissoci, J. R. N., Park, L., Mmbaga, B. T., Bettger, J. P., & Staton, C. A. (2022) · African Journal of Emergency Medicine · doi:10.1016/j.afjem.2022.08.001 · Cited by 10 · see citing works
Self-citationFeasibility of SMS booster for alcohol reduction in injury patients in Tanzania
Staton, C. A., Minnig, M. C., Phillips, A. J., Kozhumam, A. S., Pesambili, M., Suffoletto, B., Mmbaga, B. T., Ngowi, K., & Vissoci, J. R. N. (2022) · PLOS Global Public Health · doi:10.1371/journal.pgph.0000410 · Cited by 4 · see citing works
Self-citationStaton, C. A., Minja, L., de Souza, J. V. P., Gallis, J. A., Santos, P. C. P., Buono, M., Sakita, F., Ngowi, K., Boshe, J., Phillips, A. J., et al. (2025) · PLOS Medicine · doi:10.1371/journal.pmed.1004548 · Cited by 3 · see citing works
“KCMC is the regional referral center for the Kilimanjaro Region, and the emergency department typically sees around 2,000 patients seeking care for injury annually [22].”
Self-citation
- Authors
- Staton, C. A., Msilanga, D., Kiwango, G., Vissoci, J. R., de Andrade, L., Lester, R., Hocker, M., Gerardo, C. J., & Mvungi, M.
- Affiliations
- Duke University (US)
- Kilimanjaro Christian Medical Centre (TZ)
- Faculty of Medicine, Faculdade INGA, Maringá, Brazil
- State University of West of Parana/Unioeste, Foz do Iguaçu, Brazil
- London School of Hygiene & Tropical Medicine (GB)
- Corresponding author
- Staton, Catherine A.
- ORCID
- Venue
- International Journal of Injury Control and Safety Promotion
- Publisher
- Informa UK Limited
- Published
- 2015-08-04
- Volume
- 24
- Issue
- 1
- Pages
- 69-77
- ISSN
- 1745-7300 (ISSN-L)
- 1745-7319
- OpenAlex
- W2125391146
- Cited by
- 90
- References
- 2
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 5 · 2023: 14 · 2022: 14 · 2021: 10 · 2020: 6 · 2019: 8 · 2018: 11 · 2017: 9
- FWCI
- 4.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Injury Control and Safety Promotion (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Mentored Research Training Programme in collaboration with the HRSA-funded KCMC MEPI (T84HA21123-02)
- U.S. National Institutes of Health and the Duke Division of Emergency Medicine
- Topics
- Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Emergency Medicine › Trauma and Emergency Care Studies
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Keywords
- traumatic brain injury, quality of care, road traffic injuries, motorcycle riders, alcohol-related injuries, hypoxemia, secondary brain injury, low- and middle-income countries, Tanzania
- MeSH terms
- Accidents, Traffic, Brain Injuries, Traumatic, Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, Emergency Service, Hospital, Female, Humans, Infant, Male, Middle Aged, Prospective Studies, Quality of Health Care, Registries, Tanzania, Injury Severity Score, Treatment Outcome, Young Adult, Vital Signs, Quality Improvement
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