A comparison of behavioral and emotional characteristics in children with autism, Prader–Willi syndrome, and Williams syndrome
Abstract
In order to investigate unique and shared characteristics and to determine factors predictive of group classification, quantitative comparisons of behavioral and emotional problems were assessed using the Developmental Behavior Checklist (DBC-P) and the Vineland Adaptive Behavior Scales in autistic disorder, Williams syndrome (WS), and Prader-Willi syndrome (PWS). The DBC-P Total Behavior Problem Score did not differ between groups. However, at the subscale level, the autism group showed more behavioral and emotional problems in the Self-Absorbed and Communication Disturbance domains than the WS and PWS group. Discriminant analysis revealed 16 variables that predicted group membership with 90.9% accuracy. Within-group analyses revealed problems decreased with age among individuals with autism. However, as people with WS aged, they had greater difficulty with Social Relating. Distinct age and IQ correlates of adaptive behavior among groups were also found. These findings both confirm and refine the behavioral phenotypes of these developmental disorders.
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As in ASD, individuals with Prader-Willi syndrome have difficulty with social competence, are aloof and avoid eye contact.
“For example, as in ASD, individuals with PWS have difficulty with social competence (Dimitropoulos et al., 2013), are aloof and avoid eye contact (Dimitropoulos et al., 2009).”
From Oxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders (2014) · cites this paper as Dimitropoulos et al., 2009
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Self-citation
- Authors
- Dimitropoulos, A., Ho, A. Y., Klaiman, C., Koenig, K., & Schultz, R. T.
- Affiliations
- Case Western Reserve University (US)
- Children's Health Council (US)
- Yale University (US)
- Children's Hospital of Philadelphia (US)
- Corresponding author
- Dimitropoulos, Anastasia
- Venue
- Journal of Mental Health Research in Intellectual Disabilities
- Publisher
- Informa UK Limited
- Published
- 2009-06-30
- Volume
- 2
- Issue
- 3
- Pages
- 220-243
- ISSN
- 1931-5864 (ISSN-L)
- 1931-5872
- OpenAlex
- W2007699346
- Cited by
- 31
- References
- 105
- Citations by year
- 2026: 1 · 2023: 2 · 2022: 4 · 2020: 1 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 2 · 2012: 3
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Mental Health Research in Intellectual Disabilities (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Williams Syndrome Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
- Keywords
- autism spectrum disorder, Prader-Willi syndrome, Williams syndrome, behavioral problems, emotional problems, adaptive behavior, behavioral phenotypes, developmental disorders, group classification, age differences, IQ, communication disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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