Phytocomponents and evaluation of acetylcholinesterase inhibition by Ginkgo biloba L. leaves extract depending on vegetation period
Open accessAbstract
Leaves of the Ginkgo biloba L. have been identified as a source of bioactive compounds and their consumption may lead to the improvement of the brain function. During two vegetation periods, extracts of green and yellow leaves of Ginkgo biloba were analyzed for their chemical constituents and health properties. Samples were analyzed via HPLC and GC methods for the presence and content of phytochemicals. The antioxidant effect towards DPPH and ABTS radicals was studied. The antioxidant activity of samples was measured in Rancimat and Oxidograph tests along with the effectiveness of samples as inhibitors against cholinesterase. The content of individual phytochemicals was found to depend on the harvesting period and type of solvent used in the extraction process. Gingko yellow leaf extracts showed highest radical-scavenging activity as well as cholinesterase inhibition activity, and can be a valuable raw material to produce extracts possessing high cholinesterase inhibition activity.
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- Authors
- Kobus-Cisowska, J., Dziedziński, M., Szczepaniak, O., Kusek, W., Kmiecik, D., Ligaj, M., Telichowska, A., Byczkiewicz, S., Szulc, P., & Szwajgier, D.
- Affiliations
- Poznan University of Life Sciences
- Poznań University of Life Sciences (PL)
- Northern Michigan University (US)
- Poznań University of Economics and Business (PL)
- Foundation for Innovation and Technology Transfer (IN)
- University of Life Sciences in Lublin (PL)
- Corresponding author
- Dziedziński, Marcin
- ORCID
- Venue
- CyTA - Journal of Food
- Publisher
- Informa UK Limited
- Published
- 2020-01-01
- Volume
- 18
- Issue
- 1
- Pages
- 606-615
- ISSN
- 1947-6337 (ISSN-L)
- 1947-6345
- OpenAlex
- W3084138668
- Cited by
- 11
- References
- 33
- Citations by year
- 2025: 3 · 2024: 4 · 2022: 3 · 2021: 1
- FWCI
- 1.11
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- CyTA - Journal of Food (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Ministry of Science and Higher Education program as “Regional Initiative Excellence” (005/RID/2018/19)
- statutory funds of the Department of Gastronomy Sciences and Functional Foods of Poznan University of Life Sciences (506.751.03.00)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Ginkgo biloba and Cashew Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Health Sciences › Medicine › Pharmacology › Cholinesterase and Neurodegenerative Diseases
- Keywords
- Ginkgo biloba, leaf extract, acetylcholinesterase inhibition, antioxidant activity, phytochemicals, harvest time, solvent extraction, DPPH radical scavenging, ABTS radical scavenging, lipid oxidation, cognitive function
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