The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.
Elevated gut microbiome abundance of Christensenellaceae, Porphyromonadaceae and Rikenellaceae is associated with reduced visceral adipose tissue and healthier metabolic profile in Italian elderly
Open accessAbstract
Aging is accompanied by physiological changes affecting body composition and functionality, including accumulation of fat mass at the expense of muscle mass, with effects upon morbidity and quality of life. The gut microbiome has recently emerged as a key environmental modifier of human health that can modulate healthy aging and possibly longevity. However, its associations with adiposity in old age are still poorly understood. Here we profiled the gut microbiota in a well-characterized cohort of 201 Italian elderly subjects from the NU-AGE study, by 16S rRNA amplicon sequencing. We then tested for association with body composition from dual-energy X-ray absorptiometry (DXA), with a focus on visceral and subcutaneous adipose tissue. Dietary patterns, serum metabolome and other health-related parameters were also assessed. This study identified distinct compositional structures of the elderly gut microbiota associated with DXA parameters, diet, metabolic profiles and cardio-metabolic risk factors.
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Metadata
- Authors
- Tavella, T., Rampelli, S., Guidarelli, G., Bazzocchi, A., Gasperini, C., Pujos-Guillot, E., Comte, B., Barone, M., Biagi, E., Candela, M., Nicoletti, C., Kadi, F., Battista, G., Salvioli, S., O’Toole, P. W., Franceschi, C., Brigidi, P., Turroni, S., & Santoro, A.
- Venue
- Gut Microbes
- Publisher
- Informa UK Limited
- Published
- 2021-01
- Volume
- 13
- Issue
- 1
- Pages
- 1-19
- ISSN
- 1949-0976 (ISSN-L)
- 1949-0984
- OpenAlex
- W3127857648
- Cited by
- 298
- References
- 87
- FWCI
- 13.62
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Elevated gut microbiome abundance of Christensenellaceae, Porphyromonadaceae and Rikenellaceae is associated with reduced visceral adipose tissue and healthier metabolic profile in Italian elderly. https://app.cochat.ai/papers/10.1080/19490976.2021.1880221
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- Tavella, T., Rampelli, S., Guidarelli, G., Bazzocchi, A., Gasperini, C., Pujos-Guillot, E., Comte, B., Barone, M., Biagi, E., Candela, M., Nicoletti, C., Kadi, F., Battista, G., Salvioli, S., O’Toole, P. W., Franceschi, C., Brigidi, P., Turroni, S., & Santoro, A. (2021). Elevated gut microbiome abundance of Christensenellaceae, Porphyromonadaceae and Rikenellaceae is associated with reduced visceral adipose tissue and healthier metabolic profile in Italian elderly. Gut Microbes. https://doi.org/10.1080/19490976.2021.1880221
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
