The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.
Hydrodynamic Damage to Animal Cells
Abstract
Animal cells are affected by hydrodynamic forces that occur in culture vessel, transfer piping, and recovery operations such as microfiltration. Depending on the type, intensity, and duration of the force, and the specifics of the cell, the force may induce various kinds of responses in the subject cells. Both biochemical and physiological responses are observed, including apoptosis and purely mechanical destruction of the cell. This review examines the kinds of hydrodynamic forces encountered in bioprocessing equipment and the impact of those forces on cells. Methods are given for quantifying the magnitude of the specific forces, and the response thresholds are noted for the common types of cells cultured in free suspension, supported on microcarriers, and anchored to stationary surfaces.
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Cites
The formation of emulsions in definable fields of flow
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Doyle, C. (1988) · Clinical Materials · doi:10.1016/0267-6605(88)90022-4 · Cited by 497
Disruption of microbial cells for intracellular products
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Self-citationHydrodynamic effects on animal cells grown in microcarrier cultures
Croughan, M. S., Hamel, J., & Wang, D. I. C. (1987) · Biotechnology and Bioengineering · doi:10.1002/bit.260290117 · Cited by 371
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Cherry, R. S., & Papoutsakis, E. T. (1986) · Bioprocess and Biosystems Engineering · doi:10.1007/bf00369462 · Cited by 289
Animal-cell damage in sparged bioreactors
Chisti, Y. (2000) · Trends in Biotechnology · doi:10.1016/s0167-7799(00)01474-8 · Cited by 281
Self-citationHydrodynamics of Stirred Bioreactors
Nienow, A. W. (1998) · Applied Mechanics Reviews · doi:10.1115/1.3098990 · Cited by 278
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Cited by
Chisti, Y. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.02.001 · Cited by 9,524
Self-citationA novel 3D mammalian cell perfusion-culture system in microfluidic channels
Toh, Y.-C., Zhang, C., Zhang, J., Khong, Y. M., Chang, S., Samper, V. D., van Noort, D., Hutmacher, D. W., & Yu, H. (2007) · Lab on a Chip · doi:10.1039/b614872g · Cited by 414
Albumin and Mammalian cell culture: implications for biotechnology applications
Francis, G. L. (2010) · Cytotechnology · doi:10.1007/s10616-010-9263-3 · Cited by 376
Designing alginate hydrogels to maintain viability of immobilized cells
Kong, H. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00295-3 · Cited by 375
Structural and biochemical features of human Serum albumin essential for eukaryotic cell culture
Mishra, V., & Heath, R. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168411 · Cited by 295
Metadata
- Authors
- Chisti, Y.
- Venue
- Critical Reviews in Biotechnology
- Publisher
- Informa UK Limited
- Published
- 2001-01
- Volume
- 21
- Issue
- 2
- Pages
- 67-110
- ISSN
- 0738-8551 (ISSN-L)
- 1549-7801
- OpenAlex
- W2114879349
- Cited by
- 264
- References
- 92
- FWCI
- 3.08
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
