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Albumin and Mammalian cell culture: implications for biotechnology applications

Francis, Geoffrey L.·2010·Cytotechnology

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Crossref · 10.1007/s10616-010-9263-3

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  • Despite elimination of FBS, BSA often remains prevalent in cell culture media for nutrient transport and cellular stabilization.

    “Despite elimination of FBS, BSA often remains prevalent in cell culture media for nutrient transport and cellular stabilization (Francis, 2010; Price, 2017; Belinskaia et al., 2021).”

    From Challenges and solutions in transitioning to animal-free standards: a comprehensive analysis of components in human cell-based developmental neurotoxicity assays (2026) · cites this paper as Francis, 2010

    The Introduction says BSA was often included in serum-free media, and the Concluding remarks describe albumin carrying substances that support cell growth and survival. Those passages support use after FBS removal and the proposed functions, but the paper describes BSA use largely in historical terms and notes a more recent shift toward recombinant albumin; it does not establish that BSA remains prevalent. (LLM, conf=0.82)

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Authors
Francis, G. L.
Venue
Cytotechnology
Published
2010-01
Volume
62
Issue
1
Pages
1-16
ISSN
  • 0920-9069
  • 1573-0778
Cited by
330
References
3
Language
en

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