The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
The validation of the Italian Edinburgh Cognitive and Behavioural ALS Screen (ECAS)
Abstract
This study presents the Italian validation of the recently developed Edinburgh Cognitive and Behavioural ALS Screen (ECAS), a short screen for cognitive/behavioural alterations in patients with amyotrophic lateral sclerosis (ALS). We evaluated the psychometric properties of the ECAS Italian version in terms of reliability and convergent validity for both cognitive and behavioural features. Furthermore, we investigated the relationship with affective and clinical variables, in addition to ECAS usability and patients' insight into cognitive/behaviour changes. Finally, correlations between genetic and cognitive/behavioural data were analysed. We recruited 107 patients with ALS. Normative data were collected on 248 healthy subjects. Participants were administered the ECAS and two standard cognitive screening tools (FAB, MoCA), two psychological questionnaires (BDI, STAI/Y) and an ad hoc usability questionnaire. The FBI was also carried out with caregivers. Results showed that the ECAS Italian version discriminated well between patients and controls. The most prevalent deficit occurred in executive functions and fluency. Correlations were observed between the ECAS and standard cognitive screening tools and between the ECAS carer interview and the FBI, supporting its full convergent validity. In conclusion, the ECAS Italian version provides clinicians with a rapid, feasible and sensitive tool, useful to identify different profiles of cognitive-behavioural impairment in ALS.
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“the presence of cognitive impairments that significantly limited comprehension of the contents of the tests carried out and the interview, assessed using the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) [32] in the case of patients with ALS or The Montreal Cognitive Assessment (MOCA) in case of the other diseases [33].”
From Life Experiences in Neuromuscular Tracheotomized Patients in Times of Covid-19 (2023) · cites this paper as [32]
Citations
Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis
Brooks, B. R., Miller, R. G., Swash, M., & Munsat, T. L. (2000) · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders · doi:10.1080/146608200300079536 · Cited by 5,433
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., van Swieten, J. C., Seelaar, H., Dopper, E. G. P., Onyike, C. U., et al. (2011) · Brain · doi:10.1093/brain/awr179 · Cited by 5,221
DeJesus-Hernandez, M., Mackenzie, I. R., Boeve, B. F., Boxer, A. L., Baker, M., Rutherford, N. J., Nicholson, A. M., Finch, N. A., Flynn, H., Adamson, J., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.011 · Cited by 4,936
Handbook of Parametric and Nonparametric Statistical Procedures
(2004) · Technometrics · doi:10.1198/tech.2004.s209 · Cited by 4,665
The FAB: A frontal assessment battery at bedside
Dubois, B., Slachevsky, A., Litvan, I., & Pillon, B. (2000) · Neurology · doi:10.1212/wnl.55.11.1621 · Cited by 3,913
Cedarbaum, J. M., Stambler, N., Malta, E., Fuller, C., Hilt, D., Thurmond, B., & Nakanishi, A. (1999) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(99)00210-5 · Cited by 3,307
The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study
Phukan, J., Elamin, M., Bede, P., Jordan, N., Gallagher, L. B., Byrne, S., Lynch, C. M., Pender, N. P., & Hardiman, O. M. (2011) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2011-300188 · Cited by 705
Cognitive impairment in amyotrophic lateral sclerosis
Phukan, J., Pender, N. P., & Hardiman, O. M. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70265-x · Cited by 635
Screening for cognition and behaviour changes in ALS
Abrahams, S., Newton, J. L., Niven, E., Foley, J. A., & Bak, T. H. (2013) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.3109/21678421.2013.805784 · Cited by 572
Self-citation
Research works printed but not linked: 4
- Goldstein LH, 2012, Lancet Neurol, 12, 36
- Nunnally JC, 1994, Psychometric theory
- Pirani A, 2007, Dati preliminari della versione italiana. Atti IV Congresso Regionale Associazione Italiana Psicogeriatria, Bologna
- Spielberger CD, 2007, Test Manual for Form X
Cited by
Sorted by citations
Strong, M. J., Abrahams, S., Goldstein, L. H., Woolley, S., Mclaughlin, P., Snowden, J., Mioshi, E., Roberts-South, A., Benatar, M., HortobáGyi, T., et al. (2017) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.1080/21678421.2016.1267768 · Cited by 909
Self-citationHenstridge, C. M., Sideris, D. I., Carroll, E., Rotariu, S., Salomonsson, S. E., Tzioras, M., McKenzie, C.-A., Smith, C., Arnim, C. A. F. V., Ludolph, A. C., et al. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1797-4 · Cited by 136
Self-citationDecline of cognitive and behavioral functions in amyotrophic lateral sclerosis: a longitudinal study
Bersano, E., Sarnelli, M. F., Solara, V., Iazzolino, B., Peotta, L., Marchi, F. D., Facchin, A., Moglia, C., Canosa, A., Calvo, A., et al. (2020) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.1080/21678421.2020.1771732 · Cited by 72
Neuropsychological impairment in amyotrophic lateral sclerosis–frontotemporal spectrum disorder
Abrahams, S. (2023) · Nature Reviews Neurology · doi:10.1038/s41582-023-00878-z · Cited by 71
Self-citationHeidari, M. E., Nadali, J., Parouhan, A., Azarafraz, M., tabatabai, S. M., Irvani, S. S. N., eskandari, F., & Gharebaghi, A. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.03.015 · Cited by 69
Metadata
- Authors
- Poletti, B., Solca, F., Carelli, L., Madotto, F., Lafronza, A., Faini, A., Monti, A., Zago, S., Calini, D., Tiloca, C., Doretti, A., Verde, F., Ratti, A., Ticozzi, N., Abrahams, S., & Silani, V.
- Affiliations
- IRCCS Istituto Auxologico Italiano (IT)
- University of Milano-Bicocca (IT)
- Department of Neurorehabilitation Sciences, Casa Cura Policlinico, Milan, Italy,
- University of Milan (IT)
- Euan MacDonald Centre for Motor Neuron Disease Research (GB)
- Corresponding author
- Poletti, Barbara
- ORCID
- Venue
- Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Publisher
- Informa UK Limited
- Published
- 2016-05-24
- Volume
- 17
- Issue
- 7-8
- Pages
- 489-498
- ISSN
- 2167-8421 (ISSN-L)
- 2167-9223
- OpenAlex
- W2338131205
- Cited by
- 171
- References
- 38
- Citations by year
- 2026: 10 · 2025: 14 · 2024: 21 · 2023: 27 · 2022: 28 · 2021: 21 · 2020: 14 · 2019: 10 · 2018: 11 · 2017: 14 · 2016: 1
- FWCI
- 8.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (publishedVersion)
- PubMed (publishedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- Funders
- Medical Research Council (MR/K026992/1)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- ECAS, amyotrophic lateral sclerosis, cognitive screening, behavioural impairment, Italian validation, psychometric properties, convergent validity, reliability statistics, executive dysfunction, caregiver interviews, affective symptoms
- MeSH terms
- C9orf72 Protein, Age Factors, Aged, Amyotrophic Lateral Sclerosis, Mental Disorders, Cognition Disorders, Female, Humans, Italy, Male, Middle Aged, Neuropsychological Tests, Proteins, Psychometrics, Statistics as Topic, Reproducibility of Results
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