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Cited by 1,279

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Some recent advances in the chemistry and biology of transforming growth factor-beta.

Open access
Sporn, M B, Roberts, A B, Wakefield, L M, de Crombrugghe, B·1987·The Journal of cell biology

Abstract

W ITHIN the past two years, there has been an exponential increase in research on transforming growth factor-beta (TGF-beta). ~ In this brief minireview, we cannot provide a detailed survey of this topic (see referenees 56 and 73 for other reviews). Rather, we will summarize some new results, indicative of the importance of this peptide as a multifunetional regulator of cellular activity. The term ~nultifunetional" implies that TGF-beta may either stimulate cell proliferation and growth, or inhibit cell proliferation and growth, or have numerous other actions having little relationship to either of these two processes. We will develop the theme that many of the actions of TGF-beta are related to the response of cells or tissues to stress or injury, and to the repair of resultant damage. However, it is clear that there is no one principal action for TGF-beta; moreover, the almost universal cellular distribution of its receptor encompasses a very broad spectrum of target tissues.

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Metadata

Authors
Sporn, M. B., Roberts, A. B., Wakefield, L. M., & de Crombrugghe, B.
Venue
The Journal of cell biology
Published
1987-09-01
Volume
105
Issue
3
Pages
1039-1045
ISSN
  • 0021-9525 (ISSN-L)
  • 1540-8140
OpenAlex
W2108104357
Cited by
1,279
References
2
FWCI
53.24
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Some recent advances in the chemistry and biology of transforming growth factor-beta. https://app.cochat.ai/papers/10.1083/jcb.105.3.1039
The paper
Sporn, M. B., Roberts, A. B., Wakefield, L. M., & de Crombrugghe, B. (1987). Some recent advances in the chemistry and biology of transforming growth factor-beta. The Journal of cell biology. https://doi.org/10.1083/jcb.105.3.1039

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.