The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.
Open accessAbstract
An important event during wound healing is the contraction of newly formed connective tissue (granulation tissue) by fibroblasts. The role of polypeptide growth factors in the process of wound contraction was investigated by analyzing the influence of transforming growth factor beta (TGF-beta), platelet-derived growth factor on the ability of fibroblasts to contract a collagen matrix in an in vitro system. TGF-beta, but not the other growth factors tested, markedly enhanced the ability of BHK-21,3T3-L1, and human foreskin fibroblasts to contract collagen gels. These results suggest that TGF-beta released from platelets and inflammatory cells at sites of tissue injury stimulates fibroblasts to contract the provisional wound matrix and that this effect contributes to the ability of TGF-beta to accelerate wound healing.
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Cites
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(1988) · Springer eBooks · doi:10.1007/978-1-4615-1795-5 · Cited by 1,516
Some recent advances in the chemistry and biology of transforming growth factor-beta.
Sporn, M. B., Roberts, A. B., Wakefield, L. M., & de Crombrugghe, B. (1987) · The Journal of cell biology · doi:10.1083/jcb.105.3.1039 · Cited by 1,279
Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.
Wahl, S. M., Hunt, D. A., Wakefield, L. M., McCartney-Francis, N., Wahl, L. M., Roberts, A. B., & Sporn, M. B. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.16.5788 · Cited by 1,272
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Accelerated Healing of Incisional Wounds in Rats Induced by Transforming Growth Factor-β
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Granulation tissue as a contractile organ
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Cited by
Singer, A. J., & Clark, R. A. F. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411006 · Cited by 6,106
High Interstitial Fluid Pressure - an Obstacle in Cancer Therapy
Heldin, C.-H., Rubin, K., Pietras, K., & Östman, A. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1456 · Cited by 2,222
Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity
Hinz, B., Celetta, G., Tomasek, J. J., Gabbiani, G., & Chaponnier, C. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.9.2730 · Cited by 1,288
Transforming Growth Factor‐β: Major Role in Regulation of Extracellular Matrix
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Metadata
- Authors
- Montesano, R., & Orci, L.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1988-07
- Volume
- 85
- Issue
- 13
- Pages
- 4894-4897
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2066525457
- Cited by
- 561
- References
- 28
- FWCI
- 25.02
- Type
- journal article
- Language
- en
- Open access
- green
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- Montesano, R., & Orci, L. (1988). Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.85.13.4894
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
