The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Evidence for nerve growth factor-mediated paracrine effects in human epidermis.
Open accessAbstract
Nerve growth factor (NGF) is critical to the development and maintenance of the peripheral nervous system, but its possible roles in other organ systems are less well characterized. We have recently shown that human epidermal melanocytes, pigment cells derived from the neural crest, express the NGF receptor (p75 NGF-R) in vitro (Peacocke, M., M. Yaar, C. P. Mansur, M. V. Chao, and B. A. Gilchrest. 1988. Proc. Natl. Acad. Sci. USA. 85:5282-5286). Using cultured human skin-derived cells we now demonstrate that the melanocyte p75 NGF-R is functional, in that NGF stimulation modulates melanocyte gene expression; that exposure to an NGF gradient is chemotactic for melanocytes and enhances their dendricity; and that keratinocytes, the dominant epidermal cell type, express NGF messenger RNA and hence are a possible local source of NGF for epidermal melanocytes in the skin. These combined data suggest a paracrine role for NGF in human epidermis.
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Cites
The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor
Kaplan, D. R., Hempstead, B. L., Martin-Zanca, D., Chao, M. V., & Parada, L. F. (1991) · Science · doi:10.1126/science.1850549 · Cited by 1,379
Alitalo, K., Schwab, M., Lin, C. C., Varmus, H. E., & Bishop, J. M. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.6.1707 · Cited by 761
Gene Transfer and Molecular Cloning of the Human NGF Receptor
Chao, M. V., Bothwell, M. A., Ross, A. H., Koprowski, H., Lanahan, A. A., Buck, C. R., & Sehgal, A. (1986) · Science · doi:10.1126/science.3008331 · Cited by 449
Cited by
Human skin pigmentation: Melanocytes modulate skin color in response to stress
Costin, G.-E., & Hearing, V. J. (2007) · The FASEB Journal · doi:10.1096/fj.06-6649rev · Cited by 976
Mechanisms of Ultraviolet Light‐Induced Pigmentation
Gilchrest, B. A., Park, H., Eller, M. S., & Yaar, M. (1996) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1996.tb02988.x · Cited by 364
Self-citationSkin aging and oxidative stress: Equol’s anti-aging effects via biochemical and molecular mechanisms
Lephart, E. D. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.08.001 · Cited by 325
Luca, M. D., Siegrist, W., Bondanza, S., Mathor, M., Cancedda, R., & Eberle, A. N. (1993) · Journal of Cell Science · doi:10.1242/jcs.105.4.1079 · Cited by 98
Lephart, E. D. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061193 · Cited by 50
Metadata
- Authors
- Yaar, M., Grossman, K., Eller, M., & Gilchrest, B. A.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1991-11-01
- Volume
- 115
- Issue
- 3
- Pages
- 821-828
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2039403395
- Cited by
- 200
- References
- 3
- FWCI
- 2.74
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Yaar, M., Grossman, K., Eller, M., & Gilchrest, B. A. (1991). Evidence for nerve growth factor-mediated paracrine effects in human epidermis. The Journal of cell biology. https://doi.org/10.1083/jcb.115.3.821
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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