The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Sinuous is a Drosophila claudin required for septate junction organization and epithelial tube size control
Open accessAbstract
Epithelial tubes of the correct size and shape are vital for the function of the lungs, kidneys, and vascular system, yet little is known about epithelial tube size regulation. Mutations in the Drosophila gene sinuous have previously been shown to cause tracheal tubes to be elongated and have diameter increases. Our genetic analysis using a sinuous null mutation suggests that sinuous functions in the same pathway as the septate junction genes neurexin and scribble, but that nervana 2, convoluted, varicose, and cystic have functions not shared by sinuous. Our molecular analyses reveal that sinuous encodes a claudin that localizes to septate junctions and is required for septate junction organization and paracellular barrier function. These results provide important evidence that the paracellular barriers formed by arthropod septate junctions and vertebrate tight junctions have a common molecular basis despite their otherwise different molecular compositions, morphologies, and subcellular localizations.
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Cites
Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice
Nitta, T., Hata, M., Gotoh, S., Seo, Y., Sasaki, H., Hashimoto, N., Furuse, M., & Tsukita, S. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302070 · Cited by 1,917
Claudin-based tight junctions are crucial for the mammalian epidermal barrier
Furuse, M., Hata, M., Furuse, K., Yoshida, Y., Haratake, A., Sugitani, Y., Noda, T., Kubo, A., & Tsukita, S. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200110122 · Cited by 1,512
Localization of apical epithelial determinants by the basolateral PDZ protein Scribble
Bilder, D., & Perrimon, N. (2000) · Nature · doi:10.1038/35001108 · Cited by 716
Structure, function, and regulation of cellular tight junctions
Schneeberger, E. E., & Lynch, R. D. (1992) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1992.262.6.l647 · Cited by 518
Integrated activity of PDZ protein complexes regulates epithelial polarity
Bilder, D., Schober, M., & Perrimon, N. (2003) · Nature Cell Biology · doi:10.1038/ncb897 · Cited by 435
Cited by
Claudins and the Modulation of Tight Junction Permeability
Günzel, D., & Yu, A. S. L. (2013) · Physiological Reviews · doi:10.1152/physrev.00019.2012 · Cited by 1,456
Physiology and function of the tight junction
Anderson, J. M., & Van Itallie, C. M. (2009) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a002584 · Cited by 1,059
Tight junction-based epithelial microenvironment and cell proliferation
Tsukita, S., Yamazaki, Y., Katsuno, T., Tamura, A., & Tsukita, S. (2008) · Oncogene · doi:10.1038/onc.2008.344 · Cited by 375
Setting up a selective barrier at the apical junction complex
Anderson, J. M., Van Itallie, C. M., & Fanning, A. S. (2004) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2004.01.005 · Cited by 215
Origin of animal epithelia: insights from the sponge genome
Fahey, B., & Degnan, B. M. (2010) · Evolution & Development · doi:10.1111/j.1525-142x.2010.00445.x · Cited by 109
Metadata
- Authors
- Wu, V. M., Schulte, J., Hirschi, A., Tepass, U., & Beitel, G. J.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2004-01-19
- Volume
- 164
- Issue
- 2
- Pages
- 313-323
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2041787605
- Cited by
- 203
- References
- 5
- FWCI
- 9.27
- Type
- journal article
- Language
- en
- Open access
- green
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- Wu, V. M., Schulte, J., Hirschi, A., Tepass, U., & Beitel, G. J. (2004). Sinuous is a Drosophila claudin required for septate junction organization and epithelial tube size control. The Journal of Cell Biology. https://doi.org/10.1083/jcb.200309134
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