The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination
Open accessAbstract
Postnatal growth and regeneration of skeletal muscle requires a population of resident myogenic precursors named satellite cells. The transcription factor Pax7 is critical for satellite cell biogenesis and survival and has been also implicated in satellite cell self-renewal; however, the underlying molecular mechanisms remain unclear. Previously, we showed that Pax7 overexpression in adult primary myoblasts down-regulates MyoD and prevents myogenin induction, inhibiting myogenesis. We show that Pax7 prevents muscle differentiation independently of its transcriptional activity, affecting MyoD function. Conversely, myogenin directly affects Pax7 expression and may be critical for Pax7 down-regulation in differentiating cells. Our results provide evidence for a cross-inhibitory interaction between Pax7 and members of the muscle regulatory factor family. This could represent an additional mechanism for the control of satellite cell fate decisions resulting in proliferation, differentiation, and self-renewal, necessary for skeletal muscle maintenance and repair.
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Cites
Pax7 Is Required for the Specification of Myogenic Satellite Cells
Seale, P., Sabourin, L. A., Girgis-Gabardo, A., Mansouri, A., Gruss, P., & Rudnicki, M. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00066-0 · Cited by 2,339
A Pax3/Pax7-dependent population of skeletal muscle progenitor cells
Relaix, F., Rocancourt, D., Mansouri, A., & Buckingham, M. (2005) · Nature · doi:10.1038/nature03594 · Cited by 1,167
Cornelison, D. D. W., & Wold, B. J. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8721 · Cited by 935
Muscle satellite cells adopt divergent fates
Zammit, P. S., Golding, J. P., Nagata, Y., Hudon, V., Partridge, T. A., & Beauchamp, J. R. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200312007 · Cited by 921
Tajbakhsh, S., Rocancourt, D., Cossu, G., & Buckingham, M. (1997) · Cell · doi:10.1016/s0092-8674(00)80189-0 · Cited by 844
The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation
Davis, R. L., Cheng, P.-F., Lassar, A. B., & Weintraub, H. (1990) · Cell · doi:10.1016/0092-8674(90)90088-v · Cited by 765
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells
Relaix, F., Montarras, D., Zaffran, S., Gayraud-Morel, B., Rocancourt, D., Tajbakhsh, S., Mansouri, A., Cumano, A., & Buckingham, M. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200508044 · Cited by 736
Pax7 and myogenic progression in skeletal muscle satellite cells
Zammit, P. S., Relaix, F., Nagata, Y., Ruiz, A. P., Collins, C. A., Partridge, T. A., & Beauchamp, J. R. (2006) · Journal of Cell Science · doi:10.1242/jcs.02908 · Cited by 614
A common somitic origin for embryonic muscle progenitors and satellite cells
Gros, J., Manceau, M., Thomé, V., & Marcelle, C. (2005) · Nature · doi:10.1038/nature03572 · Cited by 598
Olguin, H. C., & Olwin, B. B. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.08.015 · Cited by 572
Self-citation
Cited by
Satellite Cells and the Muscle Stem Cell Niche
Yin, H., Price, F., & Rudnicki, M. A. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2011 · Cited by 2,166
Brandhorst, S., Choi, I. Y., Wei, M., Cheng, C. W., Sedrakyan, S., Navarrete, G., Dubeau, L., Yap, L. P., Park, R., Vinciguerra, M., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.05.012 · Cited by 850
Satellite Cells and Skeletal Muscle Regeneration
Dumont, N. A., Bentzinger, C. F., Sincennes, M., & Rudnicki, M. A. (2015) · Comprehensive Physiology · doi:10.1002/cphy.c140068 · Cited by 719
Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., LeBrasseur, N. K., Yan, Z., & Spiegelman, B. M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704817200 · Cited by 611
Pax7 is critical for the normal function of satellite cells in adult skeletal muscle
von Maltzahn, J., Jones, A. E., Parks, R. J., & Rudnicki, M. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307680110 · Cited by 602
Metadata
- Authors
- Olguin, H. C., Yang, Z., Tapscott, S. J., & Olwin, B. B.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2007-06-04
- Volume
- 177
- Issue
- 5
- Pages
- 769-779
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2119406072
- Cited by
- 313
- References
- 37
- FWCI
- 6.47
- Type
- journal article
- Language
- en
- Open access
- green
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