The cell biology of planar cell polarity

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

Heisenberg, C.-P., Tada, M., Rauch, G.-J., Saúde, L., Concha, M. L., Geisler, R., Stemple, D. L., Smith, J. C., & Wilson, S. W. (2000) · Nature · doi:10.1038/35011068 · Cited by 1,013 · see citing works

Dishevelled controls cell polarity during Xenopus gastrulation

Wallingford, J. B., Rowning, B. A., Vogeli, K. M., Rothbächer, U., Fraser, S. E., & Harland, R. M. (2000) · Nature · doi:10.1038/35011077 · Cited by 751 · see citing works

Flamingo, a Seven-Pass Transmembrane Cadherin, Regulates Planar Cell Polarity under the Control of Frizzled

Usui, T., Shima, Y., Shimada, Y., Hirano, S., Burgess, R. W., Schwarz, T. L., Takeichi, M., & Uemura, T. (1999) · Cell · doi:10.1016/s0092-8674(00)80046-x · Cited by 721 · see citing works

Shaping the Vertebrate Body Plan by Polarized Embryonic Cell Movements

Keller, R. E. (2002) · Science · doi:10.1126/science.1079478 · Cited by 716 · see citing works

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

Montcouquiol, M., Rachel, R. A., Lanford, P. J., Copeland, N. G., Jenkins, N. A., & Kelley, M. W. (2003) · Nature · doi:10.1038/nature01618 · Cited by 705 · see citing works

Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila

Aigouy, B., Farhadifar, R., Staple, D. B., Sagner, A., Röper, J.-C., Jülicher, F., & Eaton, S. (2010) · Cell · doi:10.1016/j.cell.2010.07.042 · Cited by 692 · see citing works

Xwnt11is a target ofXenopusBrachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway

Tada, M., & Smith, J. C. (2000) · Development · doi:10.1242/dev.127.10.2227 · Cited by 675 · see citing works

Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

Curtin, J. A., Quint, E., Tsipouri, V., Arkell, R. M., Cattanach, B. M., Copp, A. J., Henderson, D. J., Spurr, N. K., Stanier, P., Fisher, E., et al. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00374-9 · Cited by 622 · see citing works

Principles of planar polarity in animal development

Goodrich, L. V., & Strutt, D. I. (2011) · Development · doi:10.1242/dev.054080 · Cited by 568 · see citing works

Drosophila Rho-Associated Kinase (Drok) Links Frizzled-Mediated Planar Cell Polarity Signaling to the Actin Cytoskeleton

Winter, C. G., Wang, B., Ballew, A. C., Royou, A., Karess, R. E., Axelrod, J. D., & Luo, L. (2001) · Cell · doi:10.1016/s0092-8674(01)00298-7 · Cited by 555 · see citing works

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

Nishimura, T., Honda, H., & Takeichi, M. (2012) · Cell · doi:10.1016/j.cell.2012.04.021 · Cited by 520 · see citing works

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

Kibar, Z., Vogan, K. J., Groulx, N., Justice, M. J., Underhill, D. A., & Gros, P. (2001) · Nature Genetics · doi:10.1038/90081 · Cited by 504 · see citing works

Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements

Jessen, J. R., Topczewski, J., Bingham, S., Sepich, D. S., Marlow, F., Chandrasekhar, A., & Solnica-Krezel, L. (2002) · Nature Cell Biology · doi:10.1038/ncb828 · Cited by 504 · see citing works

The Role of Frizzled3 and Frizzled6 in Neural Tube Closure and in the Planar Polarity of Inner-Ear Sensory Hair Cells

Wang, Y., Guo, N., & Nathans, J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4698-05.2005 · Cited by 497 · see citing works

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

Gao, B., Song, H., Bishop, K. S., Elliot, G., Garrett, L. J., English, M. A., Andre, P., Robinson, J., Sood, R. B., Minami, Y., et al. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.01.001 · Cited by 496 · see citing works

Prickle Mediates Feedback Amplification to Generate Asymmetric Planar Cell Polarity Signaling

Tree, D., Shulman, J. M., Rousset, R., Scott, M. P., Gubb, D., & Axelrod, J. D. (2002) · Cell · doi:10.1016/s0092-8674(02)00715-8 · Cited by 460 · see citing works

Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signalingPreprint

Axelrod, J. D. (2001) · Genes & Development · doi:10.1101/gad.890501 · Cited by 449 · see citing works

Wnt5a functions in planar cell polarity regulation in mice

Qian, D., Jones, C., Rzadzinska, A. K., Mark, S., Zhang, X., Steel, K. P., Dai, X., & Chen, P. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.03.011 · Cited by 422 · see citing works

Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation

Gong, Y., Mo, C., & Fraser, S. E. (2004) · Nature · doi:10.1038/nature02796 · Cited by 420 · see citing works

Planar cell polarity signalling couples cell division and morphogenesis during neurulation

Ciruna, B. G., Jenny, A., Lee, D. W., Mlodzik, M., & Schier, A. F. (2006) · Nature · doi:10.1038/nature04375 · Cited by 400 · see citing works

Mechanical Control of Morphogenesis by Fat/Dachsous/Four-Jointed Planar Cell Polarity Pathway

Bosveld, F., Bonnet, I., Guirao, B., Tlili, S., Wang, Z., Petitalot, A., Marchand, R., Bardet, P., Marcq, P., Graner, F., et al. (2012) · Science · doi:10.1126/science.1221071 · Cited by 380 · see citing works

Regulation of Frizzled by Fat-like Cadherins during Planar Polarity Signaling in the Drosophila Compound Eye

Yang, C.-H., Axelrod, J. D., & Simon, M. A. (2002) · Cell · doi:10.1016/s0092-8674(02)00658-x · Cited by 373 · see citing works

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

Wang, J., Hamblet, N. S., Mark, S., Dickinson, M. E., Brinkman, B. C., Segil, N., Fraser, S. E., Chen, P., Wallingford, J. B., & Wynshaw-Boris, A. J. (2006) · Development · doi:10.1242/dev.02347 · Cited by 355 · see citing works

Planar Cell Polarity Acts Through Septins to Control Collective Cell Movement and Ciliogenesis

Kim, S. K., Shindo, A., Park, T. J., Oh, E. C. T., Ghosh, S., Gray, R. S., Lewis, R. A., Johnson, C. A., Attié‐Bitach, T., Katsanis, N., et al. (2010) · Science · doi:10.1126/science.1191184 · Cited by 348 · see citing works

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

Devenport, D., & Fuchs, E. V. (2008) · Nature Cell Biology · doi:10.1038/ncb1784 · Cited by 345 · see citing works

Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia

Borovina, A., Superina, S., Voskas, D., & Ciruna, B. G. (2010) · Nature Cell Biology · doi:10.1038/ncb2042 · Cited by 345 · see citing works

Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

Murdoch, J. N. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.22.2593 · Cited by 341 · see citing works

Asymmetric Localization of Frizzled and the Establishment of Cell Polarity in the Drosophila Wing

Strutt, D. I. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00184-8 · Cited by 334 · see citing works

Strabismus is asymmetrically localised and binds to Prickle and Dishevelled duringDrosophilaplanar polarity patterning

Bastock, R., Strutt, H. L., & Strutt, D. I. (2003) · Development · doi:10.1242/dev.00526 · Cited by 334 · see citing works

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

Tissir, F., Qu, Y., Montcouquiol, M., Zhou, L., Komatsu, K., Shi, D., Fujimori, T., Labeau, J., Tyteca, D., Courtoy, P. J., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2555 · Cited by 333 · see citing works

Fidelity in planar cell polarity signalling

Ma, D., Yang, C.-H., McNeill, H., Simon, M. A., & Axelrod, J. D. (2003) · Nature · doi:10.1038/nature01366 · Cited by 332 · see citing works

The Orientation of Cell Divisions Determines the Shape of Drosophila Organs

Baena-López, L. A., Baonza, A., & Garcı́a-Bellido, A. (2005) · Current Biology · doi:10.1016/j.cub.2005.07.062 · Cited by 332 · see citing works

Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases

Narimatsu, M., Bose, R., Pye, M., Zhang, L. N., Miller, B., Ching, P. V., Sakuma, R., Luga, V., Roncari, L., Attisano, L., et al. (2009) · Cell · doi:10.1016/j.cell.2009.02.025 · Cited by 330 · see citing works

The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation

Kilian, B., Mansukoski, H., Carreira-Barbosa, F., Ulrich, F., Tada, M., & Heisenberg, C. (2003) · Mechanisms of Development · doi:10.1016/s0925-4773(03)00004-2 · Cited by 327 · see citing works

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

Montcouquiol, M., Sans, N., Huss, D., Kach, J., Dickman, J. D., Forge, A., Rachel, R. A., Copeland, N. G., Jenkins, N. A., Bogani, D., et al. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4680-05.2006 · Cited by 322 · see citing works

Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells.

Wong, L., & Adler, P. N. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.123.1.209 · Cited by 317 · see citing works

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

Wang, J., Mark, S., Zhang, X., Qian, D., Yoo, S.-J., Radde‐Gallwitz, K., Zhang, Y., Lin, X., Collazo, A., Wynshaw-Boris, A. J., et al. (2005) · Nature Genetics · doi:10.1038/ng1622 · Cited by 315 · see citing works

Frizzled6 controls hair patterning in mice

Guo, N., Hawkins, C. E., & Nathans, J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402802101 · Cited by 313 · see citing works

Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing

Matakatsu, H., & Blair, S. S. (2004) · Development · doi:10.1242/dev.01254 · Cited by 303 · see citing works

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

Song, H., Hu, J., Chen, W., Elliott, G., Andre, P., Gao, B., & Yang, Y. (2010) · Nature · doi:10.1038/nature09129 · Cited by 286 · see citing works

Polarized Transport of Frizzled along the Planar Microtubule Arrays in Drosophila Wing Epithelium

Shimada, Y., Yonemura, S., Ohkura, H., Strutt, D. I., & Uemura, T. (2006) · Developmental Cell · doi:10.1016/j.devcel.2005.11.016 · Cited by 285 · see citing works

Asymmetric Homotypic Interactions of the Atypical Cadherin Flamingo Mediate Intercellular Polarity Signaling

Chen, W.-S., Antic, D., Matis, M., Logan, C. Y., Povelones, M., Anderson, G. A., Nusse, R., & Axelrod, J. D. (2008) · Cell · doi:10.1016/j.cell.2008.04.048 · Cited by 269 · see citing works

Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish

Carreira-Barbosa, F., Concha, M. L., Takeuchi, M., Ueno, N., Wilson, S. W., & Tada, M. (2003) · Development · doi:10.1242/dev.00567 · Cited by 269 · see citing works

Microtubules Enable the Planar Cell Polarity of Airway Cilia

Vladar, E. K., Bayly, R. D., Sangoram, A. M., Scott, M. P., & Axelrod, J. D. (2012) · Current Biology · doi:10.1016/j.cub.2012.09.046 · Cited by 262 · see citing works

Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling

Jenny, A., Darken, R. S., Wilson, P. A., & Mlodzik, M. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg424 · Cited by 245 · see citing works

Four-jointed Is a Golgi Kinase That Phosphorylates a Subset of Cadherin Domains

Ishikawa, H., Takeuchi, H., Haltiwanger, R. S., & Irvine, K. D. (2008) · Science · doi:10.1126/science.1158159 · Cited by 243 · see citing works

The Ankyrin Repeat Protein Diego Mediates Frizzled-Dependent Planar Polarization

Feiguin, F. M., Hannus, M., Mlodzik, M., & Eaton, S. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00010-7 · Cited by 242 · see citing works

The Planar Cell Polarity Gene Strabismus Regulates Convergence and Extension and Neural Fold Closure in Xenopus

Goto, T., & Keller, R. E. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0673 · Cited by 229 · see citing works

PCP and Septins Compartmentalize Cortical Actomyosin to Direct Collective Cell Movement

Shindo, A., & Wallingford, J. B. (2014) · Science · doi:10.1126/science.1243126 · Cited by 222 · see citing works

Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled,act independently to confer planar cell polarity

Casal, J., Lawrence, P. A., & Struhl, G. (2006) · Development · doi:10.1242/dev.02641 · Cited by 221 · see citing works

Planar polarization of node cells determines the rotational axis of node cilia

Hashimoto, M., Shinohara, K., Wang, J., Ikeuchi, S., Yoshiba, S., Meno, C., Nonaka, S., Takada, S., Hatta, K., Wynshaw-Boris, A. J., et al. (2010) · Nature Cell Biology · doi:10.1038/ncb2020 · Cited by 219 · see citing works

Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding

Jenny, A., Reynolds-Kenneally, J., Das, G., Burnett, M., & Mlodzik, M. (2005) · Nature Cell Biology · doi:10.1038/ncb1271 · Cited by 218 · see citing works

Planar polarization of the atypical myosin Dachs orients cell divisions in DrosophilaPreprint

Mao, Y., Tournier, A., Bates, P. A., et al. (2011) · Genes & Development · doi:10.1101/gad.610511 · Cited by 217 · see citing works

Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation

Yin, C., Kiskowski, M. A., Pouille, P., Farge, E., & Solnica‐Krezel, L. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200704150 · Cited by 193 · see citing works

Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins

Matakatsu, H., & Blair, S. S. (2006) · Development · doi:10.1242/dev.02401 · Cited by 189 · see citing works

Asymmetric colocalization of Flamingo, a seven-pass transmembrane cadherin, and Dishevelled in planar cell polarization

Shimada, Y., Usui, T., Yanagawa, S.-I., Takeichi, M., & Uemura, T. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00233-0 · Cited by 186 · see citing works

Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila

Wu, J., Román, Á., Carvajal-González, J. M., & Mlodzik, M. (2013) · Nature Cell Biology · doi:10.1038/ncb2806 · Cited by 180 · see citing works

Differential Stability of Flamingo Protein Complexes Underlies the Establishment of Planar Polarity

Strutt, H. L., & Strutt, D. I. (2008) · Current Biology · doi:10.1016/j.cub.2008.08.063 · Cited by 179 · see citing works

Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determination during Mouse and Xenopus Embryogenesis

Antic, D., Stubbs, J. L., Suyama, K. L., Kintner, C. R., Scott, M. P., & Axelrod, J. D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008999 · Cited by 175 · see citing works

Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes

Das, G., Jenny, A., Klein, T. J., Eaton, S., & Mlodzik, M. (2004) · Development · doi:10.1242/dev.01317 · Cited by 162 · see citing works

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

Yates, L. L., Schnatwinkel, C., Murdoch, J. N., Bogani, D., Formstone, C. J., Townsend, S., Greenfield, A., Niswander, L. A., & Dean, C. H. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq104 · Cited by 160 · see citing works

Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous

Brittle, A. L., Thomas, C., & Strutt, D. I. (2012) · Current Biology · doi:10.1016/j.cub.2012.03.053 · Cited by 156 · see citing works

The Frizzled Extracellular Domain Is a Ligand for Van Gogh/Stbm during Nonautonomous Planar Cell Polarity Signaling

Wu, J., & Mlodzik, M. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.08.004 · Cited by 155 · see citing works

Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat

Brittle, A. L., Repiso, A., Casal, J., et al. (2010) · Current Biology · doi:10.1016/j.cub.2010.03.056 · Cited by 154 · see citing works

Atypical Cadherins Dachsous and Fat Control Dynamics of Noncentrosomal Microtubules in Planar Cell Polarity

Harumoto, T., Ito, M., Shimada, Y., Kobayashi, T., Ueda, H. R., Lu, B., & Uemura, T. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.08.004 · Cited by 150 · see citing works

Asymmetric Distribution of Prickle-Like 2 Reveals an Early Underlying Polarization of Vestibular Sensory Epithelia in the Inner Ear

Deans, M. R., Antic, D., Suyama, K. L., Scott, M. P., Axelrod, J. D., & Goodrich, L. V. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.5151-06.2007 · Cited by 149 · see citing works

The Fz-Dsh Planar Cell Polarity Pathway Induces Oriented Cell Division via Mud/NuMA in Drosophila and Zebrafish

Manil-Ségalen, M., Johnston, C. A., Martin, C. A., Dumortier, J. G., Prehoda, K. E., David, N. B., Doe, C. Q., & Bellaı̈che, Y. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.10.004 · Cited by 149 · see citing works

Modulation of Fat:Dachsous Binding by the Cadherin Domain Kinase Four-Jointed

Simon, M. A., Xu, A., Ishikawa, H., & Irvine, K. D. (2010) · Current Biology · doi:10.1016/j.cub.2010.04.016 · Cited by 146 · see citing works

Regulation of PCP by the Fat signaling pathwayPreprint

Matis, M., & Axelrod, J. D. (2013) · Genes & Development · doi:10.1101/gad.228098.113 · Cited by 141 · see citing works

Mitotic internalization of planar cell polarity proteins preserves tissue polarity

Devenport, D., Oristian, D., Heller, E., & Fuchs, E. V. (2011) · Nature Cell Biology · doi:10.1038/ncb2284 · Cited by 140 · see citing works

Dynamics of Core Planar Polarity Protein Turnover and Stable Assembly into Discrete Membrane Subdomains

Strutt, H. L., Warrington, S. J., & Strutt, D. I. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.03.018 · Cited by 136 · see citing works

Asymmetric localisation of planar polarity proteins: Mechanisms and consequences

Strutt, H. L., & Strutt, D. I. (2009) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2009.03.006 · Cited by 135 · see citing works

Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A

Hannus, M., Feiguin, F. M., Heisenberg, C., & Eaton, S. (2002) · Development · doi:10.1242/dev.129.14.3493 · Cited by 130 · see citing works

Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton

Ezan, J., Lasvaux, L., Gezer, A. O., Novakovic, A. M., May‐Simera, H., Belotti, E., Lhoumeau, A., Birnbaumer, L., Beer‐Hammer, S., Borg, J., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2819 · Cited by 129 · see citing works

Microtubules provide directional information for core PCP function

Matis, M., Russler‐Germain, D. A., Hu, Q., Tomlin, C. J., & Axelrod, J. D. (2014) · eLife · doi:10.7554/elife.02893 · Cited by 129 · see citing works

Towards a model of the organisation of planar polarity and pattern in theDrosophilaabdomen

Lawrence, P. A., Casal, J., & Struhl, G. (2002) · Development · doi:10.1242/dev.129.11.2749 · Cited by 119 · see citing works

Propagation of Dachsous-Fat Planar Cell Polarity

Ambegaonkar, A. A., Pan, G., Mani, M., Feng, Y., & Irvine, K. D. (2012) · Current Biology · doi:10.1016/j.cub.2012.05.049 · Cited by 118 · see citing works

Establishment of Global Patterns of Planar Polarity during Growth of the Drosophila Wing Epithelium

Sagner, A., Merkel, M., Aigouy, B., et al. (2012) · Current Biology · doi:10.1016/j.cub.2012.04.066 · Cited by 115 · see citing works

The roles of the cadherins Fat and Dachsous in planar polarity specification in Drosophila

Thomas, C., & Strutt, D. I. (2011) · Developmental Dynamics · doi:10.1002/dvdy.22736 · Cited by 100 · see citing works

A Molecular Blueprint at the Apical Surface Establishes Planar Asymmetry in Cochlear Hair Cells

Tarchini, B., Jolicoeur, C., & Cayouette, M. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.09.011 · Cited by 97 · see citing works

Prickle/spiny-legs isoforms control the polarity of the apical microtubule network in planar cell polarity

Olofsson, J., Sharp, K. A., Matis, M., et al. (2014) · Development · doi:10.1242/dev.105932 · Cited by 87 · see citing works

Postnatal Refinement of Auditory Hair Cell Planar Polarity Deficits Occurs in the Absence of Vangl2

Copley, C. O., Duncan, J. S., Liu, C., Cheng, H., & Deans, M. R. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.1307-13.2013 · Cited by 83 · see citing works

Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements

Sepich, D. S., Usmani, M., Pawlicki, S., & Solnica‐Krezel, L. (2011) · Development · doi:10.1242/dev.053959 · Cited by 80 · see citing works

A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

Guo, Y., Zanetti, G., & Schekman, R. W. (2013) · eLife · doi:10.7554/elife.00160 · Cited by 80 · see citing works

Planar polarity genes in the Drosophila wing regulate the localisation of the FH3-domain protein Multiple Wing Hairs to control the site of hair production

Strutt, D. I., & Warrington, S. J. (2008) · Development · doi:10.1242/dev.025205 · Cited by 80 · see citing works

Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity

Struhl, G., Casal, J., & Lawrence, P. A. (2012) · Development · doi:10.1242/dev.083550 · Cited by 79 · see citing works

The multiple-wing-hairs Gene Encodes a Novel GBD–FH3 Domain-Containing Protein That Functions Both Prior to and After Wing Hair Initiation

Yan, J., Huen, D. S., Morely, T., Johnson, G., Gubb, D., Roote, J., & Adler, P. N. (2008) · Genetics · doi:10.1534/genetics.108.091314 · Cited by 77 · see citing works

Inturned Localizes to the Proximal Side of Wing Cells under the Instruction of Upstream Planar Polarity Proteins

Adler, P. N., Zhu, C., & Stone, D. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.007 · Cited by 73 · see citing works

Dachsous-Dependent Asymmetric Localization of Spiny-Legs Determines Planar Cell Polarity Orientation in Drosophila

Ayukawa, T., Akiyama, M., Mummery-Widmer, J. L., Stoeger, T., Sasaki, J., Knoblich, J. A., Senoo, H., Sasaki, T., & Yamazaki, M. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.06.009 · Cited by 72 · see citing works

The Balance of Prickle/Spiny-Legs Isoforms Controls the Amount of Coupling between Core and Fat PCP Systems

Merkel, M., Sagner, A., Gruber, F. S., et al. (2014) · Current Biology · doi:10.1016/j.cub.2014.08.005 · Cited by 63 · see citing works

A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins

Strutt, H. L., Searle, E., Thomas-MacArthur, V., et al. (2013) · Development · doi:10.1242/dev.089656 · Cited by 55 · see citing works

Strabismus Promotes Recruitment and Degradation of Farnesylated Prickle in Drosophila melanogaster Planar Polarity Specification

Strutt, H. L., Thomas-MacArthur, V., & Strutt, D. I. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003654 · Cited by 53 · see citing works

Drosophila CK1-γ, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking

Gault, W. J., Olguı́n, P., Weber, U., & Mlodzik, M. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201107137 · Cited by 52 · see citing works

Rho1 has multiple functions in Drosophila wing planar polarity

Yan, J., Lu, Q., Fang, X., & Adler, P. N. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.06.027 · Cited by 49 · see citing works

Development and dynamics of cell polarity at a glance

Campanale, J. P., Sun, T. Y., & Montell, D. J. (2017) · Journal of Cell Science · doi:10.1242/jcs.188599 · Cited by 198 · see citing works

Scribble: A master scaffold in polarity, adhesion, synaptogenesis, and proliferation

Bonello, T. T., & Peifer, M. (2019) · Journal of Cell Biology · doi:10.1083/jcb.201810103 · Cited by 127 · see citing works

Multiciliated Cells in Animals

Meunier, A., & Azimzadeh, J. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a028233 · Cited by 117 · see citing works

Polarized Organization of the Cytoskeleton: Regulation by Cell Polarity Proteins

Raman, R., Pinto, C. S., & Sonawane, M. S. (2018) · Journal of Molecular Biology · doi:10.1016/j.jmb.2018.06.028 · Cited by 56 · see citing works

Epithelial cell polarity: what flies can teach us about cancer

Bergstralh, D. T., & Johnston, D. S. (2012) · Essays in Biochemistry · doi:10.1042/bse0530129 · Cited by 24 · see citing works

The Par3/Par6/aPKC complex and epithelial cell polarity

Chen, J., & Zhang, M. (2013) · Experimental Cell Research · doi:10.1016/j.yexcr.2013.03.021 · Cited by 140 · see citing works

Cell polarity in plants—a PARspective on PINs

Geldner, N. (2008) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2008.09.009 · Cited by 51 · see citing works

An on-chip study on the influence of geometrical confinement and chemical gradient on cell polarity

Zheng, W., Xie, Y., Sun, K., Wang, D., Zhang, Y., Wang, C., Chen, Y., & Jiang, X. (2014) · Biomicrofluidics · doi:10.1063/1.4898209 · Cited by 9 · see citing works