MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Debnath, J., Muthuswamy, S. K., & Brugge, J. S. (2003) · Methods · doi:10.1016/s1046-2023(03)00032-x · Cited by 2,001 · see citing works

Plasticity of cell migration: a multiscale tuning model

Friedl, P., & Wolf, K. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200909003 · Cited by 1,356 · see citing works

Actin dynamics control SRF activity by regulation of its coactivator MAL

Miralles, F., Posern, G., Zaromytidou, A.-I., & Treisman, R. (2003) · Cell · doi:10.1016/s0092-8674(03)00278-2 · Cited by 1,327 · see citing works

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

Sahai, E. A., & Marshall, C. J. (2003) · Nature Cell Biology · doi:10.1038/ncb1019 · Cited by 1,148 · see citing works

Linking actin dynamics and gene transcription to drive cellular motile functions

Olson, E. N., & Nordheim, A. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2890 · Cited by 958 · see citing works

A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion

Overholtzer, M., Mailleux, A. A., Mouneimne, G., Normand, G., Schnitt, S. J., King, R. W., Cibas, E. S., & Brugge, J. S. (2007) · Cell · doi:10.1016/j.cell.2007.10.040 · Cited by 748 · see citing works

Physical influences of the extracellular environment on cell migration

Charras, G., & Sahai, E. A. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3897 · Cited by 678 · see citing works

Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL

Vartiainen, M., Guettler, S., Larijani, B., & Treisman, R. (2007) · Science · doi:10.1126/science.1141084 · Cited by 672 · see citing works

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

Meerbrey, K. L., Hu, G., Kessler, J. D., Roarty, K. P., Li, M. Z., Fang, J. E., Herschkowitz, J. I., Burrows, A. E., Ciccia, A., Sun, T., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019736108 · Cited by 667 · see citing works

Reassembly of contractile actin cortex in cell blebs

Charras, G., Hu, C., Coughlin, M. L., & Mitchison, T. J. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200602085 · Cited by 620 · see citing works

Cell motility through plasma membrane blebbing

Fackler, O., & Grosse, R. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200802081 · Cited by 588 · see citing works

Inhibiting eukaryotic transcription: which compound to choose? How to evaluate its activity

Bensaude, O. (2011) · Transcription · doi:10.4161/trns.2.3.16172 · Cited by 574 · see citing works

Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators

Yu, Y., Khan, J. I., Khanna, C., Helman, L. J., Meltzer, P. S., & Merlino, G. T. (2004) · Nature Medicine · doi:10.1038/nm966 · Cited by 525 · see citing works

Mechanisms of cancer cell invasion

Sahai, E. A. (2004) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2004.12.002 · Cited by 509 · see citing works

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

Medjkane, S., Pérez-Sánchez, C., Gaggioli, C., Sahai, E. A., & Treisman, R. (2009) · Nature Cell Biology · doi:10.1038/ncb1833 · Cited by 407 · see citing works

Specificity of blebbistatin, an inhibitor of myosin II

Limouze, J., Straight, A. F., Mitchison, T. J., & Sellers, J. R. (2004) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-004-6060-7 · Cited by 386 · see citing works

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblastsPreprint

Esnault, C., Stewart, A., Gualdrini, F., East, P., Horswell, S. D., Matthews, N., & Treisman, R. (2014) · Genes & Development · doi:10.1101/gad.239327.114 · Cited by 355 · see citing works

Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MAL

Baarlink, C., Wang, H., & Grosse, R. (2013) · Science · doi:10.1126/science.1235038 · Cited by 351 · see citing works

A small-molecule inhibitor of skeletal muscle myosin II

Cheung, A., Dantzig, J. A., Hollingworth, S., Baylor, S. M., Goldman, Y. E., Mitchison, T. J., & Straight, A. F. (2001) · Nature Cell Biology · doi:10.1038/ncb734 · Cited by 342 · see citing works

Morphogenic Effects of Ezrin Require a Phosphorylation-Induced Transition from Oligomers to Monomers at the Plasma Membrane

Gautreau, A. M., Louvard, D., & Arpin, M. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.1.193 · Cited by 280 · see citing works

Nucleating actin for invasion

Nürnberg, A., Kitzing, T. M., & Grosse, R. (2011) · Nature reviews. Cancer · doi:10.1038/nrc3003 · Cited by 266 · see citing works

LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics

Geneste, O., Copeland, J. W. R., & Treisman, R. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200203126 · Cited by 206 · see citing works

A non-genetic route to aneuploidy in human cancers

Krajcovic, M., Johnson, N. B., Sun, Q., Normand, G., Hoover, N., Yao, E., Richardson, A. L., King, R. W., Cibas, E. S., Schnitt, S. J., et al. (2011) · Nature Cell Biology · doi:10.1038/ncb2174 · Cited by 188 · see citing works

Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasionPreprint

Kitzing, T. M., Sahadevan, A. S., Brandt, D. T., Knieling, H., Hannemann, S., Fackler, O., Großhans, J., & Grosse, R. (2007) · Genes & Development · doi:10.1101/gad.424807 · Cited by 166 · see citing works

SRF Co-factors Control the Balance between Cell Proliferation and Contractility

Gualdrini, F., Esnault, C., Horswell, S., Stewart, A., Matthews, N., & Treisman, R. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.10.016 · Cited by 161 · see citing works

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of β1-integrin

Brandt, D. T., Baarlink, C., Kitzing, T. M., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1862 · Cited by 134 · see citing works

The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC

Ren, L., Hong, S., Cassavaugh, J. M., Osborne, T. S., Chou, A. J., Kim, S. Y., Gorlick, R. G., Hewitt, S. M., & Khanna, C. (2008) · Oncogene · doi:10.1038/onc.2008.437 · Cited by 131 · see citing works

An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells

Lorentzen, A., Bamber, J. C., Sadok, A., Elson‐Schwab, I., & Marshall, C. J. (2011) · Journal of Cell Science · doi:10.1242/jcs.074849 · Cited by 126 · see citing works

Structure of a Pentavalent G-Actin•MRTF-A Complex Reveals How G-Actin Controls Nucleocytoplasmic Shuttling of a Transcriptional Coactivator

Mouilleron, S., Langer, C. A., Guettler, S., et al. (2011) · Science Signaling · doi:10.1126/scisignal.2001750 · Cited by 111 · see citing works

G-protein-coupled receptor signaling and polarized actin dynamics drive cell-in-cell invasion

Purvanov, V., Holst, M., Khan, J., Baarlink, C., & Grosse, R. (2014) · eLife · doi:10.7554/elife.02786 · Cited by 66 · see citing works

Quantitative Analysis of Ezrin Turnover Dynamics in the Actin Cortex

Fritzsche, M., Thorogate, R., & Charras, G. (2014) · Biophysical Journal · doi:10.1016/j.bpj.2013.11.4499 · Cited by 52 · see citing works

Blebbing dynamics during endothelial cell spreading

Norman, L. L., Sengupta, K., & Aranda‐Espinoza, H. (2010) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2010.09.013 · Cited by 45 · see citing works

Entosis: Cell-in-Cell Formation that Kills Through Entotic Cell Death

Florey, O., Kim, S., & Overholtzer, M. (2015) · Current Molecular Medicine · doi:10.2174/1566524015666151026100042 · Cited by 45 · see citing works

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680 · see citing works

CDKN2A inhibits formation of homotypic cell-in-cell structures

Liang, J., Fan, J., Wang, M., Niu, Z., Zhang, Z., Yuan, L., Tai, Y., Chen, Z., Song, S., Wang, X., et al. (2018) · Oncogenesis · doi:10.1038/s41389-018-0056-4 · Cited by 49 · see citing works

Relationship of RhoA signaling activity with ezrin expression and its significance in the prognosis for breast cancer patients

Ma, L., Liu, Y., Zhang, X., Geng, C., & Zeng-huai, L. I. (2013) · Chinese Medical Journal · doi:10.3760/cma.j.issn.0366-6999.20110738 · Cited by 24 · see citing works

Effect of RhoA signaling transduction on expression of Ezrin in breast cancer cell lines.

Ma, L., Liu, Y., Zhang, X., et al. (2009) · PubMed · Cited by 8 · see citing works

Correlation of the Rac1/RhoA Pathway With Ezrin Expression in Osteosarcoma

Chiappetta, C., Leopizzi, M., Censi, F., et al. (2014) · Applied immunohistochemistry & molecular morphology · doi:10.1097/pdm.0000000000000033 · Cited by 24 · see citing works

Smooth muscle γ-actin promoter regulation by RhoA and serum response factor signaling

Carson, J. A., Culberson, D. E., Thompson, R. W., et al. (2003) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(03)00122-2 · Cited by 11 · see citing works

Modulating RhoA effectors induces transitions to oscillatory and more wavelike RhoA dynamics in Caenorhabditis elegans zygotes

Yao, B., Donoughe, S., Michaux, J. B., & Munro, E. (2022) · Molecular Biology of the Cell · doi:10.1091/mbc.e21-11-0542 · Cited by 15 · see citing works