The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Colchicine inhibition of plasma protein release from rat hepatocytes.
Open accessAbstract
Colchicine, both in vitro and in vivo, inhibits secretion of albumin and other plasma proteins. In vitro, secretion by rat liver slices is inhibited at 10-minus 6 M with maximal effect at 10-minus 5 M. Inhibition of secretion is accompanied by a concomitant retention of nonsecreted proteins within the slices. Colchicine does not inhibit protein synthesis at these concentrations. Vinblastine also inhibits plasma protein secretion but lumicolchicine, griseofulvin, and cytochalasin B do not. Colchicine also acts in vivo at 10-25 mumol/100 g body weight. Inhibition of secretion is not due to changes in the intracellular nucleotide phosphate levels. Colchicine, administered intravenously, acts within 2 min and its inhibitory effect lasts for at least 3 h. Colchicine has no effect on transport of secretory proteins in the rough or smooth endoplasmic reticulum but it causes these proteins to accumulate in Golgi-derived secretory vesicles.
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Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
Phosphorus Assay in Column Chromatography
Bartlett, G. R. (1959) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)70226-3 · Cited by 12,801
Wessells, N. K., Spooner, B. S., Ash, J. F., Bradley, M. O., Luduena, M. A., Taylor, E. L., Wrenn, J. T., & Yamada, K. M. (1971) · Science · doi:10.1126/science.171.3967.135 · Cited by 1,553
Avrameas, S., & Ternynck, T. (1969) · Immunochemistry · doi:10.1016/0019-2791(69)90178-5 · Cited by 1,462
THE MECHANISM OF ACTION OF COLCHICINE
Borisy, G. G., & Taylor, E. W. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.34.2.525 · Cited by 1,060
Olmsted, J. B., & Borisy, G. G. (1973) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.42.070173.002451 · Cited by 604
THE MECHANISM OF ACTION OF COLCHICINE
Borisy, G. G., & Taylor, E. W. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.34.2.535 · Cited by 548
THE EFFECT OF ARSENATE ON AEROBIC PHOSPHORYLATION
Crane, R. K., & Lipmann, F. (1953) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71364-1 · Cited by 543
New Hypothesis of Insulin Secretion
LACY, P. E., HOWELL, S. L., YOUNG, D. A., & FINK, C. J. (1968) · Nature · doi:10.1038/2191177a0 · Cited by 534
GOLGI FRACTIONS PREPARED FROM RAT LIVER HOMOGENATES
Ehrenreich, J. H., Bergeron, J. J. M., Siekevitz, P., & Palade, G. E. (1973) · The Journal of Cell Biology · doi:10.1083/jcb.59.1.45 · Cited by 448
Self-citation
Cited by
Microtubules and the organization of the Golgi complex
Thyberg, J., & Moskalewski, S. (1985) · Experimental Cell Research · doi:10.1016/s0014-4827(85)80032-x · Cited by 307
Plasma Retinol-Binding Protein
GOODMAN, D. S. (1984) · The Retinoids · doi:10.1016/b978-0-12-658102-7.50008-7 · Cited by 268
Involvement of vesicle coat material in casein secretion and surface regeneration.
Franke, W. W., Lüder, M. R., Kartenbeck, J., Zerban, H., & Keenan, T. W. (1976) · The Journal of cell biology · doi:10.1083/jcb.69.1.173 · Cited by 254
Mourelatos, Z., Gonatas, N. K., Stieber, A., Gurney, M. E., & Dal Canto, M. C. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5472 · Cited by 195
Proprotein Covertases Are Responsible for Proteolysis and Inactivation of Endothelial Lipase
Jin, W., Fuki, I. V., Seidah, N. G., Benjannet, S., Glick, J. M., & Rader, D. J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502264200 · Cited by 98
Metadata
- Authors
- Redman, C. M., Banerjee, D., Howell, K., & Palade, G. E.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1975-07-01
- Volume
- 66
- Issue
- 1
- Pages
- 42-59
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W1979541845
- Cited by
- 296
- References
- 27
- FWCI
- 17.53
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Redman, C. M., Banerjee, D., Howell, K., & Palade, G. E. (1975). Colchicine inhibition of plasma protein release from rat hepatocytes. The Journal of cell biology. https://doi.org/10.1083/jcb.66.1.42
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
