Immunofluorescence studies of neurofilaments in the rat and human peripheral and central nervous system

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 315,771 · see citing works

Untitled work

(1976) · Medical Entomology and Zoology · Cited by 1,328 · see citing works

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons.

Hoffman, P. N., & Lasek, R. J. (1975) · The Journal of Cell Biology · doi:10.1083/jcb.66.2.351 · Cited by 941 · see citing works

Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice

Friede, R. L., & Samorajski, T. (1970) · The Anatomical Record · doi:10.1002/ar.1091670402 · Cited by 538 · see citing works

A dialysis technique for preparing fluorescent antibody

Clark, H., & Shepard, C. C. (1963) · Virology · doi:10.1016/0042-6822(63)90292-7 · Cited by 430 · see citing works

THE FINE STRUCTURE OF NEUROFIBRILLARY TANGLES IN ALZHEIMERʼS DISEASE

Terry, R. D. (1963) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-196310000-00005 · Cited by 403 · cited 1× · see citing works

Untersuchungen �ber den Feinbau von Spinalganglien

Andres, K. H. (1961) · Cell and Tissue Research · doi:10.1007/bf00319327 · Cited by 293 · see citing works

Differentiation of astrocytes in the cerebellar cortex and the pyramidal tracts of the newborn rat. An immunofluorescence study with antibodies to a protein specific to astrocytes

Bignami, A., & Dahl, D. R. (1973) · Brain Research · doi:10.1016/0006-8993(73)90430-7 · Cited by 245 · see citing works

IMMUNOFLUORESCENCE OF DOPAMINE-β-HYDROXYLASE APPLICATION OF IMPROVED METHODOLOGY TO THE LOCALIZATION OF THE PERIPHERAL AND CENTRAL NORADRENERGIC NERVOUS SYSTEM

Hartman, B. K. (1973) · Journal of Histochemistry & Cytochemistry · doi:10.1177/21.4.312 · Cited by 244 · see citing works

NEUROFIBRILLARY PATHOLOGY

Wı́sniewski, H. M., TEKRY, R. D., & HIHANO, A. (1970) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197004000-00001 · Cited by 243 · see citing works

Fibrous proteins--neuronal organelles.

Schmitt, F. O. (1968) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.60.4.1092 · Cited by 242 · see citing works

Neuronal Microtubules, Neurofilaments, and Microfilaments

Wuerker, R. B., & Kirkpatrick, J. B. (1972) · International review of cytology · doi:10.1016/s0074-7696(08)61448-5 · Cited by 236 · see citing works

Neurofilament disguise, destruction and discipline

GILBERT, D. S., NEWBY, B. J., & Anderton, B. H. (1975) · Nature · doi:10.1038/256586a0 · Cited by 231 · see citing works

Axonal migration of protein and glycoprotein to nerve endings. I. Radioautographic analysis of the renewal of protein in nerve endings of chicken ciliary ganglion after intracerebral injection of [3H]lysine

Droz, B., Koenig, H. L., & Giamberardino, L. D. (1973) · Brain Research · doi:10.1016/0006-8993(73)90852-4 · Cited by 221 · see citing works

A LIGHT AND ELECTRON MICROSCOPE STUDY OF LONG-TERM ORGANIZED CULTURES OF RAT DORSAL ROOT GANGLIA

Bunge, M. B., Bunge, R. P., Peterson, E. R., & Murray, M. R. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.32.2.439 · Cited by 196 · see citing works

Electron microscopic study of the developing neuroblast of the dorsal root ganglion of the rabbit embryo

Tennyson, V. M. (1965) · The Journal of Comparative Neurology · doi:10.1002/cne.901240302 · Cited by 181 · see citing works

Immunochemical and immunofluorescence studies of the glial fibrillary acidic protein in vertebrates

Dahl, D. R., & Bignami, A. (1973) · Brain Research · doi:10.1016/0006-8993(73)90533-7 · Cited by 179 · see citing works

Biochemistry of the filaments of brain.

Yen, S. H., Dahl, D. R., Schachner, M., & Shelanski, M. L. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.2.529 · Cited by 174 · see citing works

Isolation of Filaments from Brain

Shelanski, M. L., Albert, S., DeVries, G. H., & Norton, W. T. (1971) · Science · doi:10.1126/science.174.4015.1242 · Cited by 134 · see citing works

Glial fibrillary acidic protein from normal and gliosed human brain Demonstration of multiple related polypeptides

Dahl, D. R., & Bignami, A. (1975) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(75)90244-5 · Cited by 120 · see citing works

ELECTRON MICROSCOPE AND EXPERIMENTAL INVESTIGATIONS OF THE NEUROFILAMENTOUS NETWORK IN DEITERS' NEURONS

Metuzals, J., & Mushynski, W. E. (1974) · The Journal of Cell Biology · doi:10.1083/jcb.61.3.701 · Cited by 114 · see citing works

The protein subunit of calf brain neurofilament

Davison, P. F., & Winslow, B. H. (1974) · Journal of Neurobiology · doi:10.1002/neu.480050204 · Cited by 110 · see citing works

Fine structure of the Pick and Hirano bodies in a case of Pick's disease

Schochet, S. S., Lampert, P. W., & Lindenberg, R. (1968) · Acta Neuropathologica · doi:10.1007/bf00686729 · Cited by 106 · see citing works

Immunological and ultrastructural studies of neurofilaments isolated from rat peripheral nerve

Schlaepfer, W. (1977) · The Journal of Cell Biology · doi:10.1083/jcb.74.1.226 · Cited by 106 · see citing works

Axoplasm architecture and physical properties as seen in the Myxicola giant axon.

GILBERT, D. S. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp011190 · Cited by 91 · see citing works

VINCRISTINE-INDUCED AXONAL ALTERATIONS IN RAT PERIPHERAL NERVE

Schlaepfer, W. W. (1971) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197107000-00012 · Cited by 75 · see citing works

Axon calibre, neurofilaments, microtubules, sheath thickness and cholesterol in cat optic nerve fibres.

Friede, R. L., Miyaghishi, T., & Hu, K. H. (1971) · PubMed · Cited by 73 · see citing works

Localization of the neurofilament protein in neuroblastoma cells by immunofluorescent staining.

Jorgensen, A. O., Subrahmanyan, L., Turnbull, C., & Kalnins, V. I. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.9.3192 · Cited by 70 · see citing works

Electrophoretic separation of nervous system proteins on exponential gradient polyacrylamide gels

Kelly, P. T., & Luttges, M. W. (1975) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1975.tb03680.x · Cited by 69 · see citing works

The protein composition of bovine myelin-free axons

Vries, G. H. D., Eng, L. F., Lewis, D. L., & Hadfield, M. G. (1976) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(76)90169-0 · Cited by 63 · see citing works

Immunofluorescence localization of the olfactory marker protein

Hartman, B. K., & Margolis, F. L. (1975) · Brain Research · doi:10.1016/0006-8993(75)90593-4 · Cited by 58 · see citing works

Microtubule and Neurofilament Densities in Amphibian Spinal Root Nerve Fibers: Relationship to Axoplasmic Transport

Smith, R. S. (1973) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y73-123 · Cited by 56 · see citing works

Chemical pathology of neurofibrils. Neurofibrillary tangles of Alzheimer's presenile-senile dementia.

Iqbal, K., Wı́sniewski, H. M., Grundke, I., Korthals, J. K., & Terry, R. D. (1975) · Journal of Histochemistry & Cytochemistry · doi:10.1177/23.7.1141687 · Cited by 49 · see citing works

Electron microscope studies of Schwann cells during the Wallerian degeneration with special reference to the cytoplasmic filaments

Bl�mcke, S., & Niedorf, H. R. (1966) · Acta Neuropathologica · doi:10.1007/bf00691081 · Cited by 49 · see citing works

The protein composition of glial and nerve fibers

Benitz, W. E., Dahl, D. R., Williams, K. W., & Bignami, A. (1976) · FEBS Letters · doi:10.1016/0014-5793(76)80523-6 · Cited by 35 · see citing works

The distribution of neurofibrils coextensive with microtubules and neurofilaments in dendrites and axons of the tectum, cerebellum, and pallium of the frog

Potter, H. D. (1971) · The Journal of Comparative Neurology · doi:10.1002/cne.901430402 · Cited by 35 · see citing works

Ultrastructure of a regular arrangement of microtubules and neurofilaments

Bertolini, B., Monaco, G., & Rossi, A. (1970) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(70)90124-3 · Cited by 33 · see citing works

The location of neurofilaments and microtubules during the postnatal development of clarke's nucleus in the kitten

Smith, D. E. (1973) · Brain Research · doi:10.1016/0006-8993(73)90487-3 · Cited by 33 · see citing works

IMMUNOFLUORESCENT STUDIES OF NEUROFILAMENTS IN THE PERIPHERAL AND CENTRAL NERVOUS SYSTEMS OF RATS AND HUMANS

Schlaeofer, W. W., & Lynch, R. G. (1976) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197605000-00099 · Cited by 7 · see citing works

IMMUNOHISTOLOGICAL LOCALIZATION OF THE NEUROFILAMENT PROTEIN IN THE HOUSE

Yen, S. H., Horn, C. V., & Shelanski, M. L. (1976) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197605000-00100 · Cited by 3 · see citing works

Intermediate filaments as mechanical integrators of cellular space

Lazarides, E. (1980) · Nature · doi:10.1038/283249a0 · Cited by 1,953 · see citing works

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

Dominantly Inherited Alzheimer Network, Preische, O., Schultz, S. A., Apel, A., Kuhle, J., Kaeser, S. A., Barro, C., Gräber, S., Kuder-Buletta, E., LaFougere, C., et al. (2019) · Nature Medicine · doi:10.1038/s41591-018-0304-3 · Cited by 927 · see citing works

Widespread occurrence of intermediate-sized filaments of the vimentin-type in cultured cells from diverse vertebrates

Franke, W. W., Schmid, E., Winter, S., Osborn, M., & Weber, K. K. (1979) · Experimental Cell Research · doi:10.1016/0014-4827(79)90418-x · Cited by 633 · see citing works

Intermediate filaments in nervous tissues

Liem, R. I. (1978) · The Journal of Cell Biology · doi:10.1083/jcb.79.3.637 · Cited by 500 · see citing works

Keratin cytoskeletons in epithelial cells of internal organs

Sun, T., Shih, C., & Green, H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.6.2813 · Cited by 483 · see citing works

Antibodies to neurofilament, glial filament, and fibroblast intermediate filament proteins bind to different cell types of the nervous system.

Yen, S. H., & Fields, K. L. (1981) · The Journal of Cell Biology · doi:10.1083/jcb.88.1.115 · Cited by 405 · see citing works

Formation of Cytoskeletal Elements During Mouse Embryogenesis

Jackson, B. W., Gründ, C., SCHMID, E., Bürki, K., Franke, W. W., & Illmensee, K. (1980) · Differentiation · doi:10.1111/j.1432-0436.1980.tb01093.x · Cited by 346 · see citing works

Slow Axonal Transport of Neurofilament Proteins: Impairment of β,β′-Iminodipropionitrile Administration

Griffin, J. W., Hoffman, P. N., Clark, A. W., Carroll, P. T., & Price, D. L. (1978) · Science · doi:10.1126/science.81524 · Cited by 337 · see citing works

Formation of cytoskeletal elements during mouse embryogenesis. IV. Ultrastructure of primary mesenchymal cells and their cell-cell interactions.

Franke, W. W., Gründ, C., Jackson, B. W., & Illmensee, K. (1983) · PubMed · Cited by 318 · see citing works

Intermediate filament proteins in the developing chick spinal cord

Tapscott, S. J., Bennett, G. S., Toyama, Y., Kleinbart, F. A., & Holtzer, H. (1981) · Developmental Biology · doi:10.1016/0012-1606(81)90313-4 · Cited by 313 · see citing works

Biochemical and immunological analysis of rapidly purified 10-nm filaments from baby hamster kidney (BHK-21) cells.

Starger, J. M., Brown, W. E., Goldman, A. E., & Goldman, R. D. (1978) · The Journal of Cell Biology · doi:10.1083/jcb.78.1.93 · Cited by 286 · see citing works

Blood-based biomarkers for Alzheimer’s disease: Current state and future use in a transformed global healthcare landscape

Hampel, H., Hu, Y., Cummings, J., Mattke, S., Iwatsubo, T., Nakamura, A., Vellas, B., O’Bryant, S., Shaw, L. M., Cho, M., et al. (2023) · Neuron · doi:10.1016/j.neuron.2023.05.017 · Cited by 283 · see citing works

CSF neurofilament light differs in neurodegenerative diseases and predicts severity and survival

Skillbäck, T., Farahmand, B., Bartlett, J. W., Rosén, C., Mattsson, N., Nägga, K., Kilander, L., Religa, D., Wimo, A., Winblad, B., et al. (2014) · Neurology · doi:10.1212/wnl.0000000000001015 · Cited by 263 · see citing works

Serum neurofilament light chain in early relapsing remitting MS is increased and correlates with CSF levels and with MRI measures of disease severity

Kuhle, J., Barro, C., Disanto, G., Mathias, A., Soneson, C., Bonnier, G., Yaldizli, Ö., Regeniter, A., Derfuss, T., Canales, M., et al. (2016) · Multiple Sclerosis Journal · doi:10.1177/1352458515623365 · Cited by 257 · see citing works

Neurofilament proteins of rat peripheral nerve and spinal cord.

Schlaepfer, W. W., & Freeman, L. A. (1978) · The Journal of Cell Biology · doi:10.1083/jcb.78.3.653 · Cited by 215 · see citing works

Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury

Graham, N., Zimmerman, K. A., Moro, F., Heslegrave, A., Maillard, S. A., Bernini, A., Miroz, J., Donat, C. K., Lopez, M. Y., Bourke, N., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abg9922 · Cited by 198 · see citing works

Renal function is associated with blood neurofilament light chain level in older adults

Akamine, S., Marutani, N., Kanayama, D., Gotoh, S., Maruyama, R., Yanagida, K., Sakagami, Y., Mori, K., Adachi, H., Kozawa, J., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-76990-7 · Cited by 213 · see citing works

Specificity of desmin to avian and mammalian muscle cells

Lazarides, E., & Baizer, D. R. (1978) · Cell · doi:10.1016/0092-8674(78)90128-9 · Cited by 178 · see citing works

Intermediate filaments: a family of homologous structures

Anderton, B. H. (1981) · Journal of Muscle Research and Cell Motility · doi:10.1007/bf00711866 · Cited by 175 · see citing works

Simultaneous Expression of Two Different Types of Intermediate Sized Filaments in Mouse Keratinocytes Proliferating in vitro

Franke, W. W., SCHMID, E., Breitkreutz, D., Lueder, M., Boukamp, P., Fusenig, N. E., Osborn, M., & Weber, K. K. (1979) · Differentiation · doi:10.1111/j.1432-0436.1979.tb01010.x · Cited by 160 · see citing works

Sensory and autonomic innervation of non-hairy and hairy human skin

Bj�rklund, H., Dalsgaard, C. ‐., Jonsson, C.-E., & Hermansson, A. (1986) · Cell and Tissue Research · doi:10.1007/bf00221851 · Cited by 157 · see citing works

Brain postsynaptic densities: the relationship to glial and neuronal filaments.

Matus, A. I., Pehling, G., Ackermann, M., & Maeder, J. (1980) · The Journal of Cell Biology · doi:10.1083/jcb.87.2.346 · Cited by 146 · see citing works

An immunocytochemical study of cutaneous innervation and the distribution of neuropeptides and protein gene product 9.5 in man and commonly employed laboratory animals

Karanth, S., Springall, D. R., Kuhn, D. M., Levene, M. M., & Polak, J. M. (1991) · American Journal of Anatomy · doi:10.1002/aja.1001910404 · Cited by 132 · see citing works

Desmin from avian smooth muscle. Purification and partial characterization.

Huiatt, T. W., Robson, R., Arakawa, N., & Stromer, M. H. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)43672-1 · Cited by 129 · see citing works

Differential Location of Different Types of Intermediate-Sized Filaments in Various Tissues of the Chicken Embryo

SCHMID, E., Tapscott, S. J., Bennett, G. S., Croop, J. M., FELLIN, S. A., Holtzer, H., & Franke, W. W. (1979) · Differentiation · doi:10.1111/j.1432-0436.1979.tb01031.x · Cited by 125 · see citing works

Astrocyte cultures from adult rat brain. Derivation, characterization and neurotrophic properties of pure astroglial cells from corpus callosum

Lindsay, R. M., Barber, P. C., Sherwood, M. R. C., Zimmer, J., & Raisman, G. (1982) · Brain Research · doi:10.1016/0006-8993(82)90257-8 · Cited by 123 · see citing works

The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease

Jung, Y., & Damoiseaux, J. S. (2023) · Brain · doi:10.1093/brain/awad267 · Cited by 117 · see citing works

Co-expression of cytokeratin and vimentin intermediate-sized filaments in renal cell carcinomas

Waldherr, R., & Schwechheimer, K. (1985) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/bf00739959 · Cited by 109 · see citing works

Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease

Alawode, D. O. T., Heslegrave, A., Ashton, N. J., Karikari, T. K., Simrén, J., Montoliu‐Gaya, L., Pannee, J., O’Connor, A., Weston, P. S. J., Lantero‐Rodriguez, J., et al. (2021) · Journal of Internal Medicine · doi:10.1111/joim.13332 · Cited by 100 · see citing works

Phosphorylation of subunit proteins of intermediate filaments from chicken muscle and nonmuscle cells

O’Connor, C. M., Balzer, D. R., & Lazarides, E. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.2.819 · Cited by 105 · see citing works

Dynamics of the neuronal intermediate filaments.

Okabe, S., Miyasaka, H., & Hirokawa, N. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.121.2.375 · Cited by 103 · see citing works

Microheterogeneity ("neurotypy") of neurofilament proteins.

Goldstein, M. E., Sternberger, L. A., & Sternberger, N. H. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.10.3101 · Cited by 103 · see citing works

Ultrastructural three‐dimensional reconstruction of group III and group IV sensory nerve endings (“free nerve endings”) in the knee joint capsule of the cat: Evidenence for multiple receptive sites

Heppelmann, B., Meßlinger, K., Neiss, W. F., & Schmidt, R. F. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902920107 · Cited by 102 · see citing works

Neurofilament Light Chain in Cerebrospinal Fluid and Blood as a Biomarker for Neurodegenerative Diseases: A Systematic Review and Meta-Analysis

Wang, S.-Y., Chen, W., Xu, W., Li, J., Hou, X., Ou, Y., Yu, J., & Tan, L. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190615 · Cited by 95 · see citing works

The neurofilament triplet is present in distinct subpopulations of neurons in the central nervous system of the guinea-pig

Vickers, J. C., & Costa, M. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90077-f · Cited by 91 · see citing works

Extensive acute axonal damage in pediatric multiple sclerosis lesions

Pfeifenbring, S., Bunyan, R. F., Metz, I., Röver, C., Huppke, P., Gärtner, J., Lucchinetti, C. F., & Brück, W. (2015) · Annals of Neurology · doi:10.1002/ana.24364 · Cited by 88 · see citing works

Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases

Zerr, I., Schmitz, M., Karch, A., Villar‐Piqué, A., Kanata, Ε., Golańska, E., Lucena, D. D., Karsanidou, A., Hermann, P., Knipper, T., et al. (2018) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2017.12.008 · Cited by 87 · see citing works

Simultaneous Separation and Purification of Neurofilament and Glial Filament Proteins from Brain

Liem, R. K. H. (1982) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1982.tb10865.x · Cited by 88 · see citing works

Expression of keratin and vimentin intermediate filaments in rabbit bladder epithelial cells at different stages of benzo[a]pyrene-induced neoplastic progression.

Summerhayes, I. C., Cheng, Y. S., Sun, T., & Chen, L. B. (1981) · The Journal of Cell Biology · doi:10.1083/jcb.90.1.63 · Cited by 85 · see citing works

Constitutive aggregates of intermediate-sized filaments of the vimentin and cytokeratin type in cultured hepatoma cells and their dispersal by butyrate

Borenfreund, E., Schmid, E., Bendich, A., & Franke, W. W. (1980) · Experimental Cell Research · doi:10.1016/0014-4827(80)90428-0 · Cited by 82 · see citing works

Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides

Högberg, H. T., Kinsner‐Ovaskainen, A., Härtung, T., Coecke, S., & Bal‐Price, A. (2008) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2008.12.014 · Cited by 77 · see citing works

Occurrence and distribution of different neurochemical markers in the human dental pulp

Luthman, J., Luthman, D., & Hökfelt, T. (1992) · Archives of Oral Biology · doi:10.1016/0003-9969(92)90089-q · Cited by 77 · see citing works

Neurofilament and glial fibrillary acid protein-related immunoreactivity in rodent enteric nervous system

Björklund, H., Dahl, D. R., & Seigkr, A. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90153-2 · Cited by 77 · see citing works

Immunofluorescent Visualization of 100 Å Filaments in Different Cultured Chick Embryo Cell Types

Bennett, G. S., FELLINI, S. A., & Holtzer, H. (1979) · Differentiation · doi:10.1111/j.1432-0436.1979.tb00992.x · Cited by 77 · see citing works

CSF neurogranin as a neuronal damage marker in CJD: a comparative study with AD

Blennow, K., Lucena, D. D., Zetterberg, H., Villar‐Piqué, A., Karch, A., Vidal, E., Hermann, P., Schmitz, M., Ferrer, I., Zerr, I., et al. (2019) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-320155 · Cited by 74 · see citing works

Serum neurofilament light chain: a biomarker of neuronal injury in vasculitic neuropathy

Bischof, A., Manigold, T., Barro, C., Heijnen, I., Berger, C. T., Derfuss, T. J., Kühle, J., & Daikeler, T. D. (2017) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2017-212045 · Cited by 72 · see citing works

Calcium-mediated breakdown of glial filaments and neurofilaments in rat optic nerve and spinal cord

Schlaepfer, W. W., & Zimmerman, U. P. (1981) · Neurochemical Research · doi:10.1007/bf00964040 · Cited by 72 · see citing works

PROTEIN COMPOSITION OF AXONS and MYELIN FROM RAT and HUMAN PERIPHERAL NERVES

Micko, S., & Schlaepfer, W. W. (1978) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1978.tb12397.x · Cited by 72 · see citing works

Presence of neurofilament protein in Alzheimer's neurofibrillary tangles (ANT)

Ishii, T., Haga, S., & Tokutake, S. (1979) · Acta Neuropathologica · doi:10.1007/bf00691151 · Cited by 68 · see citing works

Distribution of neurofilament-immunoreactive nerve fibers in human skin

Dalsgaard, C., Bj�rklund, H., Jonsson, C. E., Hermansson, A., & Dahl, D. R. (1984) · Histochemistry and Cell Biology · doi:10.1007/bf00490102 · Cited by 65 · see citing works

The axon reaction in motor and sensory neurones of mice studied by a monoclonal antibody marker of neurofilament protein

Moss, T., & Lewkowicz, S. J. (1983) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(83)90068-0 · Cited by 63 · see citing works

NEUROFILAMENTS

Shelanski, M. L., & Liem, R. K. H. (1979) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1979.tb11699.x · Cited by 63 · see citing works

Specific neuronal localization by immunofluorescence of 10 nm filament polypeptides

Anderton, B. H., Thorpe, R., Cohen, J., Selvendran, S. Y., & Woodhams, P. L. (1980) · Journal of Neurocytology · doi:10.1007/bf01205022 · Cited by 62 · see citing works

Postnatal Development of Periodontal Innervation in Rat Incisors: An Immunohistochemical Study Using Protein Gene Product 9.5 Antibody.

Ohshima, H., Maeda, T., Sato, O., & Takano, Y. (1993) · Archivum histologicum japonicum · doi:10.1679/aohc.56.385 · Cited by 61 · see citing works

Localization of substance P and neurofilament immunoreactive fibers in the lumbar facet joint capsule and supraspinous ligament of the rabbit

El-Bohy, A. A., Cavanaugh, J. M., Getchell, M. L., Bulas, T., Getchell, T. V., & King, A. I. (1988) · Brain Research · doi:10.1016/0006-8993(88)90386-1 · Cited by 60 · see citing works

Diagnostic accuracy of CSF neurofilament light chain protein in the biomarker-guided classification system for Alzheimer's disease

Lista, S., Toschi, N., Baldacci, F., Zetterberg, H., Blennow, K., Kilimann, I., Teipel, S. J., Cavedo, E., dos Santos, A. M., Epelbaum, S., et al. (2017) · Neurochemistry International · doi:10.1016/j.neuint.2017.05.010 · Cited by 60 · see citing works

Immunohistochemical studies of the neurochemical markers, CGRP, enkephalin, galanin, γ-MSH, NPY, PHI, proctolin, PTH, somatostatin, SP, VIP, tyrosine hydroxylase and neurofilament in nerves and cells of the human attached gingiva

Luthman, J., Johansson, O., Ahlström, U., & Kvint, S. (1988) · Archives of Oral Biology · doi:10.1016/0003-9969(88)90039-8 · Cited by 59 · see citing works

Neuron-specific enolase, neurofilament protein and S-100 protein in the olfactory mucosa of human fetuses

Takahashi, S., Iwanaga, T., Takahashi, Y., Nakano, Y., & Fujita, T. (1984) · Cell and Tissue Research · doi:10.1007/bf00217293 · Cited by 58 · see citing works

Regenerating dorsal roots and the nerve entry zone: An immunofluorescence study with neurofilament and laminin antisera

Bignami, A., Chi, N. H., & Dahl, D. R. (1984) · Experimental Neurology · doi:10.1016/0014-4886(84)90152-3 · Cited by 57 · see citing works

Immunohistochemical localization of neurofilament antigen in rat cerebellum

Matus, A. I., Ng, M., & Jones, D. H. (1979) · Journal of Neurocytology · doi:10.1007/bf01214806 · Cited by 55 · see citing works

The teleost cone cytoskeleton. Localization of actin, microtubules, and intermediate filaments.

Nagle, B. W., Okamoto, C., Taggart, B. N., & Burnside, B. (1986) · PubMed · Cited by 54 · see citing works

Appearance and distribution of neurofilament immunoreactivity in iris nerves

Seiger, Å., Dahl, D. R., Lièvre, C. A., & Björklund, H. (1984) · The Journal of Comparative Neurology · doi:10.1002/cne.902230310 · Cited by 54 · see citing works

Distribution of neurofilament-positive nerve fibres and sensory endings in the human anterior cruciate ligament

Krauspe, R., Schmitz, F., Z�ller, G., & Drenckhahn, D. (1995) · Archives of Orthopaedic and Trauma Surgery · doi:10.1007/bf00444261 · Cited by 53 · see citing works

Assessment of immunological properties of neurofilament triplet proteins

Schlaepfer, W. W., Lee, V., & Wu, H. ‐. (1981) · Brain Research · doi:10.1016/0006-8993(81)91098-2 · Cited by 52 · see citing works

IMMUNOLOGICAL MARKERS IN ASTROCYTES

Dahl, D. R., Björklund, H., & Bignami, A. (1986) · Elsevier eBooks · doi:10.1016/b978-0-12-250453-2.50005-0 · Cited by 51 · see citing works

Future avenues for Alzheimer's disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery

Hampel, H. J., Vergallo, A., Caraci, F., Cuello, A. C., Lemercier, P., Vellas, B. J., Giudici, K. V., Baldacci, F., Hänisch, B., Haberkamp, M., et al. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108081 · Cited by 50 · see citing works

Neurodegeneration, synaptic dysfunction, and gliosis are phenotypic of Alzheimer dementia

Merluzzi, A. P., Carlsson, C. M., Johnson, S. C., Schindler, S. E., Asthana, S., Blennow, K., Zetterberg, H., & Bendlin, B. B. (2018) · Neurology · doi:10.1212/wnl.0000000000005901 · Cited by 49 · see citing works

Substance P, neurofilament, peripherin and SSEA4 immunocytochemistry of human dorsal root ganglion neurons obtained from post-mortem tissue: a quantitative morphometric analysis

Holford, L. C., Case, P., & Lawson, S. N. (1994) · Journal of Neurocytology · doi:10.1007/bf01262058 · Cited by 49 · see citing works

Purification of desmin from adult mammalian skeletal muscle

O'SHEA, J. M., Robson, R., Hartzer, M. K., Huiatt, T. W., Rathbun, W. E., & Stromer, M. H. (1981) · Biochemical Journal · doi:10.1042/bj1950345 · Cited by 49 · see citing works

Emerging Biomarkers of Multiple Sclerosis in the Blood and the CSF: A Focus on Neurofilaments and Therapeutic Considerations

Biernacki, T., Kokas, Z., Sandi, D., Füvesi, J., Fricska‐Nagy, Z., Faragó, P., Kincses, Z. T., Klivènyi, P., Bencsik, K., & Vécsei, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063383 · Cited by 47 · see citing works

Cerebrospinal fluid biomarkers for Alzheimer disease and subcortical axonal damage in 5,542 clinical samples

Skillbäck, T. B., Zetterberg, H., Blennow, K., & Mattsson, N. (2013) · Alzheimer s Research & Therapy · doi:10.1186/alzrt212 · Cited by 48 · see citing works

Diagnostic and prognostic value of plasma neurofilament light and total-tau in sporadic Creutzfeldt-Jakob disease

Zerr, I., Villar‐Piqué, A., Hermann, P., Schmitz, M., Varges, D., Ferrer, I., Riggert, J., Zetterberg, H., Blennow, K., & Llorens, F. (2021) · Alzheimer s Research & Therapy · doi:10.1186/s13195-021-00815-6 · Cited by 44 · see citing works

Astroglial and axonal proteins in isolated brain filaments I. Isolation of the glial fibrillary acidic protein and of an immunologically active cyanogen bromide peptide from brain filament preparations of bovine white matter

Dahl, D. R., & Bignami, A. (1979) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(79)90161-2 · Cited by 44 · see citing works

Different Proteins Associated with 10-Nanometer Filaments in Cultured Chick Neurons and Nonneuronal Cells

Bennett, G. S., Tapscott, S. J., Kleinbart, F. A., Antin, P. B., & Holtzer, H. (1981) · Science · doi:10.1126/science.6163217 · Cited by 42 · see citing works

Alzheimer’s Disease Biomarkers Revisited From the Amyloid Cascade Hypothesis Standpoint

Alawode, D. O. T., Fox, N. C., Zetterberg, H., & Heslegrave, A. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.837390 · Cited by 40 · see citing works

Retrograde Axonal Transport of Endogenous Proteins in Sciatic Nerve Demonstrated by Covalent Labeling in Vivo

Fink, D. J., & Gainer, H. (1980) · Science · doi:10.1126/science.6154312 · Cited by 41 · see citing works

Axonal transport of proteins. A new view using in vivo covalent labeling.

Fink, D. J., & Gainer, H. (1980) · The Journal of Cell Biology · doi:10.1083/jcb.85.2.175 · Cited by 41 · see citing works

Cell Type-Specific Cell Surface Antigens in the Cerebellum

Schachner, M., & Willinger, M. (1979) · Progress in brain research · doi:10.1016/s0079-6123(08)61291-1 · Cited by 40 · see citing works

Conversion of amylase-secreting rat pancreatic AR42J cells to neuronlike cells by activin A.

Ohnishi, H., Ohgushi, N., Tanaka, S., Mogami, H., Nobusawa, R., Mashima, H., Furukawa, M., Mine, T., Shimada, O., & Ishikawa, H. A. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117922 · Cited by 40 · see citing works

Expression of neurofilament proteins by Purkinje cells: ultrastructural immunolocalization with monoclonal antibodies

Langley, O. K., Sternberger, N. H., & Sternberger, L. A. (1988) · Brain Research · doi:10.1016/0006-8993(88)90052-2 · Cited by 38 · see citing works

Isolation and characterization of neurofilaments from mammalian brain

Runge, M. S., Schlaepfer, W. W., & Williams, R. C. (1981) · Biochemistry · doi:10.1021/bi00504a028 · Cited by 36 · see citing works

Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease

Hofmann, A., Häsler, L. M., Lambert, M., Kaeser, S. A., Gräber‐Sultan, S., Obermüller, U., Kuder-Buletta, E., la Fougère, C. J., Laske, C., Vöglein, J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-52937-8 · Cited by 35 · see citing works

Immunohistochemical study of neurochemical markers in gingiva obtained from periodontitis‐affected sites

Luthman, J., Friskopp, J., Dahliöf, G., Ahlström, U., Sjöström, L., & Johansson, O. (1989) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1989.tb01792.x · Cited by 34 · see citing works

Developmental expression of neurotypy revealed by immunocytochemistry with monoclonal antibodies

Goldstein, M. E., Sternberger, N. H., & Sternberger, L. A. (1982) · Journal of Neuroimmunology · doi:10.1016/0165-5728(82)90023-6 · Cited by 33 · see citing works

Immunohistochemical demonstration of the nerves in human dental pulp with antisera against neurofilament protein and glia-specific S-100 protein.

Maeda, T., Iwanaga, T., Fujita, T., & Kobayashi, S. (1985) · Archivum histologicum japonicum · doi:10.1679/aohc.48.123 · Cited by 30 · see citing works

Differential effects of neurodegeneration biomarkers on subclinical cognitive decline

Merluzzi, A. P., Vogt, N. M., Norton, D., Jonaitis, E. M., Clark, L. R., Carlsson, C. M., Johnson, S. C., Asthana, S., Blennow, K., Zetterberg, H., et al. (2019) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1016/j.trci.2019.02.004 · Cited by 28 · see citing works

Altered protein composition of isolated human cortical neurons in alzheimer disease

Selkoe, D. J. (1980) · Annals of Neurology · doi:10.1002/ana.410080504 · Cited by 29 · see citing works

Neurofilament-like and glial fibrillary acidic protein-like immunoreactivities in rat and guinea-pig sympathetic ganglia in situ and after perturbation

Elfvin, L.-G., Björklund, H., Dahl, D. R., & Seiger, Å. (1987) · Cell and Tissue Research · doi:10.1007/bf00214657 · Cited by 28 · see citing works

First appearance of laminin in peripheral nerve, cerebral blood vessels and skeletal muscle of the rat embryo

Bignami, A., Chi, N. H., & Dahl, D. R. (1984) · International Journal of Developmental Neuroscience · doi:10.1016/0736-5748(84)90073-x · Cited by 27 · see citing works

Monoclonal antibodies to central nervous system antigens

Franko, M. C., Masters, C. L., Gibbs, C. J., & Gajdusek, D. C. (1981) · Journal of Neuroimmunology · doi:10.1016/0165-5728(81)90019-9 · Cited by 27 · see citing works

Association and multimodal model of retinal and blood-based biomarkers for detection of preclinical Alzheimer’s disease

Ravichandran, S., Snyder, P. J., Alber, J., Murchison, C., Chaby, L. E., Jeromin, A., & Arthur, E. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01668-5 · Cited by 26 · see citing works

Organization of the guinea-pig uterine innervation. Distribution of immunoreactivities for different neuronal markers. Effects of chemical- and pregnancy-induced sympathectomy

Alm, P., Lundberg, L., Wharton, J., & Polak, J. M. (1988) · The Histochemical Journal · doi:10.1007/bf01745608 · Cited by 26 · see citing works

Characterization of the anti-neural antibodies in the Sera of leprosy patients

Eustis-Turf, E. P., Benjamins, J. A., & Lefford, M. J. (1986) · Journal of Neuroimmunology · doi:10.1016/0165-5728(86)90015-9 · Cited by 25 · see citing works

Fine-Structural and Related Aspects of Nonmuscle-Cell Motility

Buckley, I. K. (1981) · Springer eBooks · doi:10.1007/978-1-4684-8196-9_5 · Cited by 24 · see citing works

The association of desmin with the developing myofibrils of cultured embryonic rat heart myocytes

Fuseler, J. W., & Shay, J. W. (1982) · Developmental Biology · doi:10.1016/0012-1606(82)90051-3 · Cited by 23 · see citing works

The Role of Intermediate (10-nm) Filaments in the Development and Integration of the Myofibrillar Contractile Apparatus in the Embryonic Mammalian Heart

Fuseler, J. W., Shay, J. W., & Feit, H. (1981) · Springer eBooks · doi:10.1007/978-1-4684-8196-9_6 · Cited by 22 · see citing works

Alzheimer’s Disease and Cognitive Decline in Patients with Cardiovascular Diseases Along the Heart-Brain Axis

Trieu, C., van Harten, A. C., Leeuwis, A. E., Exalto, L. G., Hooghiemstra, A. M., Verberk, I. M. W., Allaart, C. P., Rocca, H. B., Kappelle, L. J., van Oostenbrugge, R. J., et al. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-231096 · Cited by 21 · see citing works

Acute Blood Levels of Neurofilament Light Indicate One-Year White Matter Pathology and Functional Impairment in Repetitive Mild Traumatic Brain Injured Mice

Moro, F., Lisi, I., Tolomeo, D., Vegliante, G., Pascente, R., Mazzone, E., Hussain, R., Micotti, E., Dallmeier, J., Pischiutta, F., et al. (2022) · Journal of Neurotrauma · doi:10.1089/neu.2022.0252 · Cited by 20 · see citing works

Immunohistochemical study of neuronal markers in human gingiva with phenytoin‐induced overgrowth

Luthman, J., Dahllöf, G., Modéer, T., & Johansson, O. (1988) · European Journal Of Oral Sciences · doi:10.1111/j.1600-0722.1988.tb01565.x · Cited by 21 · see citing works

An Immunohistochemical Study of Canine Tissues with Vimentin, Desmin, Glial Fibrillary Acidic Protein, and Neurofilament Antisera

Vos, J. H., van den Ingh, T. S. G. A. M., Misdorp, W., Ramaekers, F. C. S., van Mil, F. N., & de Neijs, M. (1989) · Zentralblatt für Veterinärmedizin Reihe A · doi:10.1111/j.1439-0442.1989.tb00767.x · Cited by 21 · see citing works

Localization of organ-specific antigens in the nervous system of the rat

Weinrauder, H., & Lach, B. A. (1977) · Acta Neuropathologica · doi:10.1007/bf00703316 · Cited by 2 · see citing works

IMMUNOFLUORESCENT STUDIES OF NEUROFILAMENTS IN THE PERIPHERAL AND CENTRAL NERVOUS SYSTEMS OF RATS AND HUMANS

Schlaeofer, W. W., & Lynch, R. G. (1976) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-197605000-00099 · Cited by 7 · see citing works

Immunohistochemical differences between neurofilaments in perikarya, dendrites and axons

Dahl, D. R. (1983) · Experimental Cell Research · doi:10.1016/0014-4827(83)90352-x · Cited by 116 · see citing works

Immunohistochemical localization of neurofilament antigen in rat cerebellum

Matus, A. I., Ng, M., & Jones, D. H. (1979) · Journal of Neurocytology · doi:10.1007/bf01214806 · Cited by 55 · see citing works

Immunocytologic analyses of 10 nm intermediate filaments in the nervous system of Myxicola.

Eng, L. F., Lasek, R. J., Bigbee, J. W., & Eng, D. L. (1980) · Journal of Histochemistry & Cytochemistry · doi:10.1177/28.12.7014711 · Cited by 11 · see citing works