The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Immunohistochemical localization of a macrophage-specific antigen in developing mouse retina: phagocytosis of dying neurons and differentiation of microglial cells to form a regular array in the plexiform layers.
Open accessAbstract
In the developing mouse retina degenerating neurons can be observed initially in the ganglion cell layer followed by a phase of cell death in the inner nuclear layer. Using an immunohistochemical method to localize the mouse macrophage specific antigen F4/80, we show that macrophages migrate from the vascular supply overlying the developing retina and phagocytose the degenerating neurons. The macrophages subsequently differentiate to become the microglia of the retina and form a regularly spaced distribution across the retina in the inner and outer plexiform layers. These experiments provide strong evidence for the mesodermal origin of central nervous system microglia.
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Citations
Cites
Hsu, S. M., Raine, L., & Fanger, H. (1981) · Journal of Histochemistry & Cytochemistry · doi:10.1177/29.4.6166661 · Cited by 14,140
F4/80, a monoclonal antibody directed specifically against the mouse macrophage
Austyn, J. M., & Gordon, S. (1981) · European Journal of Immunology · doi:10.1002/eji.1830111013 · Cited by 1,579
Self-citationThe mosaic of nerve cells in the mammalian retina
Wässle, H., & Riemann, H. J. (1978) · Proceedings of the Royal Society of London. Series B. Biological Sciences · doi:10.1098/rspb.1978.0026 · Cited by 533
Newman, S. L., Henson, J. E., & Henson, P. M. (1982) · The Journal of experimental medicine · doi:10.1084/jem.156.2.430 · Cited by 318
The loss of ganglion cells in the developing retina of the rat
Potts, R. A., Dreher, B., & Bennett, M. R. (1982) · Developmental Brain Research · doi:10.1016/0165-3806(82)90013-x · Cited by 267
Plasminogen activator–plasmin system and neuronal migration
Moonen, G., Grau-Wagemans, M. P., & Selak, I. (1982) · Nature · doi:10.1038/298753a0 · Cited by 253
Imamoto, K., & Leblond, C. P. (1978) · Journal of Comparative Neurology · doi:10.1002/cne.901800109 · Cited by 234
Hirsch, S., Austyn, J. M., & Gordon, S. (1981) · The Journal of experimental medicine · doi:10.1084/jem.154.3.713 · Cited by 213
Self-citationHume, D., & Gordon, S. (1983) · The Journal of Experimental Medicine · doi:10.1084/jem.157.5.1704 · Cited by 190
Self-citationLing, E. A., Penney, D., & Leblond, C. P. (1980) · Journal of Comparative Neurology · doi:10.1002/cne.901930304 · Cited by 175
Cited by
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
Lawson, L. J., Perry, V. H., Dri, P., & Gordon, S. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90229-w · Cited by 2,045
Self-citationMicroglia states and nomenclature: A field at its crossroads
Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., et al. (2022) · Neuron · doi:10.1016/j.neuron.2022.10.020 · Cited by 1,973
Self-citationMicroglial physiology: unique stimuli, specialized responses
Ransohoff, R. M., & Perry, V. H. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132528 · Cited by 1,858
Self-citationDevelopmental cell death: morphological diversity and multiple mechanisms
Clarke, P. H. (1990) · Anatomy and Embryology · doi:10.1007/bf00174615 · Cited by 1,695
Microglia Biology: One Century of Evolving Concepts
Prinz, M., Jung, S., & Priller, J. (2019) · Cell · doi:10.1016/j.cell.2019.08.053 · Cited by 1,525
Metadata
- Authors
- Hume, D. A., Perry, V. H., & Gordon, S.
- Venue
- The Journal of cell biology
- Publisher
- Rockefeller University Press
- Published
- 1983-07-01
- Volume
- 97
- Issue
- 1
- Pages
- 253-257
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2129008615
- Cited by
- 444
- References
- 18
- FWCI
- 12.66
- Type
- journal article
- Language
- en
- Open access
- green
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- Hume, D. A., Perry, V. H., & Gordon, S. (1983). Immunohistochemical localization of a macrophage-specific antigen in developing mouse retina: phagocytosis of dying neurons and differentiation of microglial cells to form a regular array in the plexiform layers. The Journal of cell biology. https://doi.org/10.1083/jcb.97.1.253
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
