The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
STUDIES ON ANTIBODY PRODUCTION
Open accessAbstract
When lymph node fragments from previously immunized rabbits were stimulated in vitro to produce a secondary response, the continuous presence of 50 µg/ml (0.15 mM) of chloramphenicol in the medium during the entire incubation period of 15 to 21 days produced nearly complete suppression of the response. Concentrations as low as 5 µg/ml (0.015 mM) produced approximately 80 per cent suppression of the response. When 50 µg/ml of chloramphenicol was present during only the first 6 days of culture, the secondary response was reduced 90 per cent. When it was absent for the first 6 days but present for the next 9 to 15 days, the response was reduced only 40 per cent. Since over 95 per cent of the antibody of the secondary response in most experiments appeared in the medium after the 6th day, chloramphenicol apparently inhibits antibody production by interfering with some early phase of the response. It is suggested that this interference involves messenger RNA and that animal cells have appeared resistant to this drug only because their complement of messenger RNA present when the drug has been added is stable over the short periods during which protein synthesis has usually been studied.
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Nirenberg, M. W., & Matthaei, J. H. (1961) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.47.10.1588 · Cited by 1,630
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Relation of Oxygen and Temperature in the Preservation of Tissues by Refrigeration
Hanks, J. H., & Wallace, R. E. (1949) · Experimental Biology and Medicine · doi:10.3181/00379727-71-17131 · Cited by 957
Djordjevic, B., & Szybalski, W. (1960) · The Journal of Experimental Medicine · doi:10.1084/jem.112.3.509 · Cited by 645
Effect of Actinomycin D on Cellular Nucleic Acid Synthesis and Virus Production
Reich, E., Franklin, R. M., Shatkin, A. J., & Tatum, E. L. (1961) · Science · doi:10.1126/science.134.3478.556 · Cited by 596
CHARACTERISTICS AND STABILIZATION OF DNAASE-SENSITIVE PROTEIN SYNTHESIS IN E. COLI EXTRACTS
Matthaei, J., & Nirenberg, M. W. (1961) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.47.10.1580 · Cited by 349
Gale, E. F., & Folkes, J. P. (1953) · Biochemical Journal · doi:10.1042/bj0530493 · Cited by 339
Synthesis of Hemoglobin in a Cell-free System
Allen, E. H., & Schweet, R. S. (1962) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)60370-9 · Cited by 325
Eagle, H. (1955) · The Journal of Experimental Medicine · doi:10.1084/jem.102.5.595 · Cited by 323
Actinomycin D Inhibition of Deoxyribonucleic Acid-Dependent Synthesis of Ribonucleic Acid
Goldberg, I. H., & Rabinowitz, M. (1962) · Science · doi:10.1126/science.136.3513.315 · Cited by 304
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Towards an understanding of the adjuvant action of aluminium
Marrack, P., McKee, A. S., & Munks, M. W. (2009) · Nature Reviews Immunology · doi:10.1038/nri2510 · Cited by 887
Aluminum Hydroxide Adjuvants Activate Caspase-1 and Induce IL-1β and IL-18 Release
Li, H., Nookala, S., & Re, F. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.8.5271 · Cited by 332
Ballesta, J., Carlei, F., Bishop, A. E., Steel, J. H., Gibson, S. J., Fahey, M., Hennessey, R., Domin, J., Bloom, S. R., & Polak, J. M. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90037-1 · Cited by 121
Effects of neuropeptide F on regeneration in Girardia tigrina (Platyhelminthes)
Kreshchenko, N. D., Sedelnikov, Z., Sheiman, I. M., Reuter, M., Maule, A. G., & Gustafsson, M. K. S. (2008) · Cell and Tissue Research · doi:10.1007/s00441-007-0519-y · Cited by 28
Metadata
- Authors
- Ambrose, C. T., & Coons, A. H.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1963-06-01
- Volume
- 117
- Issue
- 6
- Pages
- 1075-1088
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2227670160
- Cited by
- 328
- References
- 27
- FWCI
- 16.02
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
