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EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS
Open accessAbstract
Experiments utilizing chromosome marker and histological techniques in combination with parabiosis and transplanatation procedures have demonstrated an inflow of blood-home stem cells into the chick embryo thymic rudiment. There is close similarity between the histological picture in the chick and in the mouse thymic rudiment, and it is proposed that a similar developmental process takes place in both. It may be concluded that the epithelial component of the thymic rudiment, rather than producing lymphoid cells itself, furnishes an inductive environment for the proliferation and differentiation of stem cells derived extrinsically.
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Cited by
Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations
Weissman, I. L., Anderson, D. J., & Gage, F. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.387 · Cited by 948
Georgopoulos, K., Moore, D. D., & Derfler, B. (1992) · Science · doi:10.1126/science.1439790 · Cited by 464
Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence
Yoshimoto, M., Porayette, P., Glosson, N. L., Conway, S. J., Carlesso, N., Cardoso, A. A., Kaplan, M. H., & Yoder, M. C. (2012) · Blood · doi:10.1182/blood-2011-12-397489 · Cited by 178
The embryonic origins of hematopoietic stem cells: a tale of hemangioblast and hemogenic endothelium
BOLLEROT, K., POUGET, C., & JAFFREDO, T. (2005) · APMIS · doi:10.1111/j.1600-0463.2005.apm_317.x · Cited by 65
Metadata
- Authors
- Moore, M. A. S., & Owen, J. J. T.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 1967-10-01
- Volume
- 126
- Issue
- 4
- Pages
- 715-726
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2141535774
- Cited by
- 496
- References
- 0
- FWCI
- 9.97
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS. https://app.cochat.ai/papers/10.1084/jem.126.4.715
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- Moore, M. A. S., & Owen, J. J. T. (1967). EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.126.4.715
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
