Cited by 165Tuberculosis Research and EpidemiologyImmunotherapy and Immune ResponsesT-cell and B-cell Immunology

The DOI matches its Crossref record; 32 of the 33 references it cites were found in a registry or an index.

Characterization of Human CD8+ T Cells Reactive with Mycobacterium tuberculosis–infected Antigen-presenting Cells

Open access

Lewinsohn, David M., Alderson, Mark R., Briden, Andria L., Riddell, Stanley R., Reed, Steven G., Grabstein, Kenneth H.·1998·The Journal of Experimental Medicine

DOI 10.1084/jem.187.10.1633PMC PMC2212289

Open this paper in CoChat — free account

Abstract

Previous studies in murine models, including those using the β2 microglobulin knockout mouse, have suggested an important role for CD8+ T cells in host defense to Mycobacterium tuberculosis (Mtb). At present, little is understood about these cells in the human immune response to tuberculosis. This report demonstrates the existence of human Mtb-reactive CD8+ T cells. These cells are present preferentially in persons infected with Mtb and produce interferon γ in response to stimulation with Mtb-infected target cells. Recognition of Mtb-infected cells by these CD8+ T cells is restricted neither by the major histocompatibility complex (MHC) class I A, B, or C alleles nor by CD1, although it is inhibited by anti–MHC class I antibody. The Mtb-specific CD8+ T cells recognize an antigen which is generated in the proteasome, but which does not require transport through the Golgi-ER. The data suggest the possible use of nonpolymorphic MHC class Ib antigen presenting structures other than CD1.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1084/jem.187.10.1633

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.
Flynn, J. L., Chan, J., Triebold, K. J., Dalton, D. K., Stewart, T. A., & Bloom, B. R. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.178.6.2249 · Cited by 2,468
Proliferating dendritic cell progenitors in human blood.
Romani, N., Grüner, S., Brang, D., Kämpgen, E., Lenz, A., Trockenbacher, B., Konwalinka, G., Fritsch, P. O., Steinman, R. M., & Schuler, G. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.1.83 · Cited by 1,841
Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice
Flynn, J. L., Goldstein, M. M., Chan, J., Triebold, K. J., Pfeffer, K., Lowenstein, C. J., Schrelber, R., Mak, T. W., & Bloom, B. R. (1995) · Immunity · doi:10.1016/1074-7613(95)90001-2 · Cited by 1,678
Recognition of a lipid antigen by CD1-restricted αβ+ T cells
Beckman, E. M., Porcelli, S. A., Morita, C. T., Behar, S. M., Furlong, S. T., & Brenner, M. B. (1994) · Nature · doi:10.1038/372691a0 · Cited by 977
The global tuberculosis situation and the new control strategy of the World Health Organization
Kochi, A. (1991) · Tubercle · doi:10.1016/0041-3879(91)90017-m · Cited by 849
Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.
Flynn, J. L., Goldstein, M. M., Triebold, K. J., Koller, B. H., & Bloom, B. R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.24.12013 · Cited by 793
Immunogenicity and protective efficacy of a tuberculosis DNA vaccine
Huygen, K., Content, J., Denis, O., Montgomery, D. L., Yawman, A. M., Deck, R. R., DeWitt, C. M., Orme, I. M., Baldwin, S. L., D'Souza, C. D., et al. (1996) · Nature Medicine · doi:10.1038/nm0896-893 · Cited by 628
Phagocytic processing of bacterial antigens for class I MHC presentation to T cells
Pfeifer, J. D., Wick, M. J., Roberts, R. L., Findlay, K., Normark, S. J., & Harding, C. V. (1993) · Nature · doi:10.1038/361359a0 · Cited by 615 · cited 2×
“However, particulate antigens have been shown to gain access to the MHC class I pathway (18, 19), although the efficiency of these pathways remains controversial (20).”
Background
Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages.
Kovacsovics-Bankowski, M., Clark, K., Benacerraf, B., & Rock, K. L. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.11.4942 · Cited by 601
CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen
Porcelli, S. A., Morita, C. T., & Brenner, M. B. (1992) · Nature · doi:10.1038/360593a0 · Cited by 572

Flagged first, then by citations

Show all 33 references

1 of the 33 references couldn’t be matched to a known paper.

Sorted by citations

Items 101–165 of 165

Identification of Mycobacterium tuberculosis vaccine candidates using human CD4+ T-cells expression cloning
Coler, R. N., Dillon, D. C., Skeiky, Y. A. W., Kahn, M., Orme, I. M., Lobet, Y., Reed, S. G., & Alderson, M. R. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.10.056 · Cited by 34
Self-citation
A combined immuno-informatics and structure-based modeling approach for prediction of T cell epitopes of secretory proteins of Mycobacterium tuberculosis
Vani, J., Shaila, M. S., Chandra, N. R., & Nayak, R. (2006) · Microbes and Infection · doi:10.1016/j.micinf.2005.09.012 · Cited by 33
Live antigen carriers as tools for improved anti-tuberculosis vaccines
Hess, J. ⁄. R., & Kaufmann, S. H. E. (1999) · FEMS Immunology & Medical Microbiology · doi:10.1016/s0928-8244(98)00132-1 · Cited by 33
Potent immune responses of Ag-specific Vγ2Vδ2+ T cells and CD8+ T cells associated with latent stage of Mycobacterium tuberculosis coinfection in HIV-1-infected humans
Shao, L., Zhang, W., Zhang, S., Chen, C. Y., Jiang, W., Xu, Y., Meng, C., Weng, X., & Chen, Z. W. (2008) · AIDS · doi:10.1097/qad.0b013e3283117f18 · Cited by 32
Human Dendritic Cells Presenting Adenovirally Expressed Antigen Elicit Mycobacterium tuberculosis –Specific CD8 + T Cells
Lewinsohn, D. A., Lines, R. A., & Lewinsohn, D. M. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2110094 · Cited by 31
Self-citation
Cytolytic T-cell responses to human dendritic cells and macrophages infected with BCG and recombinant BCG secreting listeriolysin
Conradt, P., Hess, J., & Kaufmann, S. H. E. (1999) · Microbes and Infection · doi:10.1016/s1286-4579(99)80077-x · Cited by 31
Vaccinia expression of secreted proteins: tissue plasminogen activator signal sequence enhances expression and immunogenicity of Ag85
Malin, A. S., Huygen, K., Content, J., Mackett, M., Brandt, L., Andersen, P. L., Smith, S. M., & Dockrell, H. M. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)01323-x · Cited by 30
CD40 Ligand Trimer Enhances the Response of CD8+ T Cells to Mycobacterium tuberculosis
Samten, B., Wizel, B., Shams, H., Weis, S. E., Klucar, P., Wu, S., Vankayalapati, R., Thomas, E. K., Okada, S., Krensky, A. M., et al. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.6.3180 · Cited by 30
Assessment of cell mediated immunogenicity of Mycobacterium leprae-derived antigens
Maeda, Y., Gidoh, M., Ishii, N., Mukai, C., & Makino, M. (2003) · Cellular Immunology · doi:10.1016/s0008-8749(03)00078-9 · Cited by 29
Evaluation of T-cell responses to peptides with MHC class I-binding motifs derived from PE_PGRS 33 protein of Mycobacterium tuberculosis
Chaitra, M. G., Shaila, M. S., & Nayak, R. (2007) · Journal of Medical Microbiology · doi:10.1099/jmm.0.46928-0 · Cited by 29
CD1a and Factor XIIIa Immunohistochemistry in Leprosy: A Possible Role of Dendritic Cells in the Pathogenesis of Mycobacterium leprae Infection
Quaresma, J. A. S., de Oliveira, M. F. A., Guimarães, Â. C. R., de Brito, E. B., Brito, R. B., Pagliari, C., de Brito, A. C., Xavier, M. B., & Duarte, M. I. S. (2009) · American Journal of Dermatopathology · doi:10.1097/dad.0b013e31819f1997 · Cited by 28
Cytotoxic T cells and mycobacteria
Silva, C. L., Bonato, V. L. D., de Lima, K. M. C., Coelho‐Castelo, A. A. M., Faccioli, L. H., Sartori, A., de Souza, A. O., & Leão, S. C. (2001) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(01)00099-4 · Cited by 31
Nonclassical MHC Ib-restricted CD8+ T Cells Recognize Mycobacterium tuberculosis-Derived Protein Antigens and Contribute to Protection Against Infection
Shang, S., Siddiqui, S., Bian, Y., Zhao, J., & Wang, C.-R. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005688 · Cited by 26
Review: IRF and Tuberculosis
Pine, R. I. (2002) · Journal of Interferon & Cytokine Research · doi:10.1089/107999002753452629 · Cited by 25
In vitro control of Mycobacterium bovis by macrophages
Aldwell, F. E., Wedlock, D. N., Slobbe, L. J., Griffin, J. F. T., Buddle, B. M., & Buchan, G. S. (2001) · Tuberculosis · doi:10.1054/tube.2000.0280 · Cited by 26
The immunogenic peptide for Th1 development
Takatsu, K., & Kariyone, A. (2002) · International Immunopharmacology · doi:10.1016/s1567-5769(02)00209-6 · Cited by 26
Functional Characterization of Class Ia- and Non-Class Ia-Restricted Chlamydia-Reactive CD8+ T Cell Responses in Humans
Gervassi, A. L., Probst, P., Stamm, W. E., Marrazzo, J. M., Grabstein, K. H., & Alderson, M. R. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.8.4278 · Cited by 25
Self-citation
Cross‐presentation of peptides from intracellular pathogens by MHC class I molecules
Blanchard, N., & Shastri, N. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05135.x · Cited by 24
Host Immune Response to Intracellular Bacteria: A Role for MHC-Linked Class-Ib Antigen-Presenting Molecules
Soloski, M. J., Szperka, M. E., Davies, A., & Wooden, S. L. (2000) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.2000.22426.x · Cited by 21
Topological journey of parasite-derived antigens for presentation by MHC class I molecules
Blanchard, N., & Shastri, N. (2010) · Trends in Immunology · doi:10.1016/j.it.2010.08.004 · Cited by 20
Inhaled Therapies for Tuberculosis and the Relevance of Activation of Lung Macrophages By Particulate drug-delivery Systems
Verma, R. K., Singh, A. K., Mohan, M., Agrawal, A. K., & Misra, A. (2011) · Therapeutic Delivery · doi:10.4155/tde.11.34 · Cited by 18
Characterization of effector functions of human peptide-specific CD4+ T-cell clones for an intracellular pathogen
Klucar, P., Barnes, P. F., Kong, Y., Samten, B., Tvinnereim, A., Spallek, R., Nepom, G. T., Singh, M., & Shams, H. (2008) · Human Immunology · doi:10.1016/j.humimm.2008.05.008 · Cited by 19
Profiling the T-cell receptor repertoire of patient with pleural tuberculosis by high-throughput sequencing
Li, D., Gao, G., Li, Z., Sun, W., Li, X., Chen, N., Sun, J., & Yang, Y. (2014) · Immunology Letters · doi:10.1016/j.imlet.2014.08.012 · Cited by 17
Selective expansion of perforin-positive CD8+ T cells by immature dendritic cells infected with live Bacillus Calmette-Guérin mycobacteria
Tsunetsugu‐Yokota, Y., Tamura, H., Tachibana, M., Ogata, K., Honda, M., & Takemori, T. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.72.1.115 · Cited by 16
Strain-Dependent Variation inMycobacterium bovisBCG-Induced Human T-Cell Activation and Gamma Interferon Production In Vitro
Aguirre-Blanco, A. M., Lukey, P. T., Cliff, J. M., & Dockrell, H. M. (2007) · Infection and Immunity · doi:10.1128/iai.01611-06 · Cited by 16
Human CD1d Functions as a Transplantation Antigen and a Restriction Element in Mice
Wang, B., Chun, T., Rulifson, I. C., Exley, M. A., Balk, S. P., & Wang, C.-R. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.6.3829 · Cited by 16
CD8 T Cells in Tuberculosis
Kaufmann, S. H. E., & Flynn, J. L. (2004) · doi:10.1128/9781555817657.ch29 · Cited by 16
Interleukin‐15 in Mycobacterial Infection of Antigen‐Presenting Cells
Maeurer, M. J., Seliger, Trinder, Gerdes, & Seitzer (1999) · Scandinavian Journal of Immunology · doi:10.1046/j.1365-3083.1999.00593.x · Cited by 15
Efficient Ex Vivo Stimulation ofMycobacterium tuberculosis-Specific T Cells by Genetically DetoxifiedBordetella pertussisAdenylate Cyclase Antigen Toxoids
Wilkinson, K. A., Simsova, M., Schölvinck, E. H., Šebo, P., Leclerc, C., Vordermeier, H. M., Dickson, S. J., Brown, J. R.-M., Davidson, R. N., Pasvol, G., et al. (2005) · Infection and Immunity · doi:10.1128/iai.73.5.2991-2998.2005 · Cited by 15
Human CD8+ T cells recognize epitopes of the 28-kDa hemolysin and the 38-kDa antigen ofMycobacterium tuberculosis
Shams, H., Barnes, P. F., Weis, S. E., Klucar, P., & Wizel, B. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0403138 · Cited by 13
The Missing Link in Correlates of Protective Tuberculosis Immunity: Recognizing the Infected Cell
Lewinsohn, D. M., & Lewinsohn, D. A. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.869057 · Cited by 13
Self-citation
Human leucocyte antigen‐A2 restricted and Mycobacterium tuberculosis 19‐kDa antigen‐specific CD8+ T‐cell responses are oligoclonal and exhibit a T‐cell cytotoxic type 2 response cytokine‐secretion pattern
Höhn, H., Kortsik, C., Nilges, K., Necker, A., Freitag, K., Tully, G., Neukirch, C., & Maeurer, M. J. (2001) · Immunology · doi:10.1046/j.1365-2567.2001.01307.x · Cited by 13
Why is IFN-γ insufficient to control tuberculosis?
Flynn, J. L. (1999) · Trends in Microbiology · doi:10.1016/s0966-842x(99)01611-x · Cited by 13
Cytotoxicity responses to selected ESAT-6 and CFP-10 peptides in tuberculosis
Kumar, M. M., & Raja, A. (2010) · Cellular Immunology · doi:10.1016/j.cellimm.2010.08.004 · Cited by 12
Upregulation of T‐Cell‐Stimulating Activity of Mycobacteria‐Infected Macrophages
Kimura, H. J., Maeda, Y., Takeshita, F., Takaoka, L. E., Matsuoka, M., & Makino, M. (2004) · Scandinavian Journal of Immunology · doi:10.1111/j.0300-9475.2004.01472.x · Cited by 12
Vaccination strategies to enhance local immunity and protection against Mycobacterium tuberculosis
Klucar, P., Barnes, P. F., Kong, Y., Howard, S. T., Pang, X., Huang, F.-F., Tvinnereim, A., Samten, B., & Shams, H. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.01.119 · Cited by 11
A Novel Tuberculosis Antigen Identified from Human Tuberculosis Granulomas*
Yang, Y., Jin, D., Hu, S., Zhang, Y., Zheng, X., Zheng, J., Liao, M., Chen, X., Graner, M. W., Liu, H., et al. (2015) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m114.045237 · Cited by 9
Cytolytic T Cells in the Immune Response to Mycobacterium tuberculosis
Stenger, S. (2001) · Scandinavian Journal of Infectious Diseases · doi:10.1080/003655401753382495 · Cited by 9
Mycobacterium bovis-Infected Cervine Alveolar Macrophages Secrete Lymphoreactive Lipid Antigens
Aldwell, F. E., Dicker, B. L., Tatley, F. D. S., Cross, M. F., Liggett, S., Mackintosh, C. G., & Griffin, J. F. T. (2000) · Infection and Immunity · doi:10.1128/iai.68.12.7003-7009.2000 · Cited by 7
Development of novel tuberculosis vaccines
Hess, J., & Kaufmann, S. H. E. (1999) · Comptes Rendus de l Académie des Sciences - Series III - Sciences de la Vie · doi:10.1016/s0764-4469(00)87192-9 · Cited by 7
LiveLegionella pneumophilainduces MUC5AC production by airway epithelial cells independently of intracellular invasion
Morinaga, Y., Yanagihara, K., Araki, N., Migiyama, Y., Nagaoka, K., Harada, Y., Yamada, K., Hasegawa, H., Nishino, T., Izumikawa, K., et al. (2012) · Canadian Journal of Microbiology · doi:10.1139/w11-123 · Cited by 6
T-cell clones derived by CD3 stimulation from hepatitis C virus explanted liver tissue are not representative of dominant clones present in vivo
Davey, M. P., Rosen, H. R., Woody, C. N., Haley, D. P., Kurkinen, J., & Lewinsohn, D. M. (2001) · Liver Transplantation · doi:10.1053/jlts.2001.26058 · Cited by 6
Self-citation
Generation of MR1-Restricted T Cell Clones by Limiting Dilution Cloning of MR1 Tetramer+ Cells
Cansler, M. E., Null, M. D., Meermeier, E. W., Swarbrick, G. M., Lewinsohn, D. M., & Harriff, M. J. (2019) · Methods in molecular biology · doi:10.1007/978-1-0716-0207-2_15 · Cited by 5
Self-citation
Role of T Cell Subsets in the Modulation of Mycobacterium avium Growth within Human Monocytes
Shiratsuchi, H., Krukovets, I., & Ellner, J. J. (2000) · Cellular Immunology · doi:10.1006/cimm.2000.1652 · Cited by 5
Ubiquitin-fusion degradation pathway: A new strategy for inducing CD8 cells specific for mycobacterial HSP65
Shen, J., Hisaeda, H., Chou, B., Yu, Q., Tu, L., & Himeno, K. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.11.009 · Cited by 4
Mycobacterium chelonae sensitisation induces CD4+‐mediated cytotoxicity against BCG
Ho, P., Zhang, L., Wei, X., & Seah, G. T. (2009) · European Journal of Immunology · doi:10.1002/eji.200838933 · Cited by 3
The Expanding Role of HLA-E in Host Defense: A Target for Broadly Applicable Vaccines and Immunotherapies
Rafieiyan, M., Manna, M. L. L., Dieli, F., Caccamo, N., & Badami, G. D. (2025) · Cells · doi:10.3390/cells14241983 · Cited by 2
Immune biomarkers as key targets in managing tuberculosis: A systematic review
Saini, M., Nagarajan, K., Bhardwaj, S., Ghai, R., & Mishra, A. (2025) · Current Proteomics · doi:10.1016/j.curpro.2025.100050 · Cited by 2
Immunobiology of Pediatric Tuberculosis: Lessons Learned and Implications for an Improved TB-Vaccine
Boer, M. C., Lewinsohn, D., & Lancioni, C. (2017) · Journal of Pediatric Infectious Diseases · doi:10.1055/s-0037-1607233 · Cited by 2
Self-citation
Immunity against Mycobacterium tuberculosis: Defense strategies
Розов, С. М., Popova, N. A., & Дейнеко, Е. В. (2016) · Biology Bulletin Reviews · doi:10.1134/s2079086416060062 · Cited by 1
CD8+ lymphocytes in immunity against tuberculosis
Li, J., Simonson, A. W., & Flynn, J. L. (2025) · The Journal of Immunology · doi:10.1093/jimmun/vkaf268 · Cited by 2
Aetiopathogenesis, immunology and microbiology of tuberculosis
Barreira‐Silva, P., Torrado, E., Nebenzahl-Guimaraes, H., Källenius, G., & Correia‐Neves, M. (2018) · European Respiratory Society eBooks · doi:10.1183/2312508x.10020917 · Cited by 1
Editorial Response: Variation in Clinical and Immune Responses to Bacille Calmette‐Guérin‐Implications for an Improved Tuberculosis Vaccine
Ernst, J. (1999) · Clinical Infectious Diseases · doi:10.1086/515202 · Cited by 1
Vaccines Against Mycobacterium tuberculosis: An Overview from Preclinical Animal Studies to the Clinic
Rhea, N. C., Susan, L., & Steven, G. (2012) · InTech eBooks · doi:10.5772/29886
Fortschritte in der Impfstoffentwicklung gegen Tuberkulose
Hess, J., & Kaufmann, S. H. E. (1999) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s001030050189
Mucosal immunity against mycobacterial infection
Rahman, M. J. (2010) · DiVA (Stockholm University)
Review Recent advances in our understanding of human host responses to tuberculosisW Schluger
Schluger, N. W. (2001)
Presentation of lipid antigen: cloning and sequencing equine CDI
Hines, S. A. (2007) · Research Exchange (Washington State University)
M. tuberculosisSomatic Antigen Specific CD8+T cell Responses in BCG-Vaccinated Subjects
Cho, J. E., Cho, S. N., Lee, K. W., Park, S. K., & Cho, S. (2005) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2005.59.3.272
Fortschritte in der Impfstoffentwicklung gegen Tuberkulose
Hess, J., & Kaufmann, H. E. (1999) · Springer eBooks · doi:10.1007/978-3-662-38283-7_125
A sinalização através do receptor Axl desempenha um papel protetor para o hospedeiro durante a tuberculose experimental
Correa, A. A. D. S. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.17.2022.tde-10042023-162038
Etude de la réponse lymphocitaire T non conventionnelle restreinte par HLA-E lors de l'infection par le cytomégalovirus chez les patients transplantés rénaux
Jouand, N. (2018) · theses.fr (ABES) · doi:10.70675/18e7dc6dz9200z4287za058z7d76fed92075
Predictive Value of Inflammatory Cytokines as Potential Biomarkers for Takayasu Arteritis: A Systematic Review and Meta-Analysis
Li, Y., Qiang, Z., Chang, W., Xiao, Y., Guo, L., & Yan, S. (2026) · Vascular Research · doi:10.15302/vr.2025.0005
Identification of candidate HLA-E binding peptides from Mycobacterium tuberculosis using phage secretome library screening and computational modeling
Masondo, N., Gordon, M. L., & Chiliza, T. E. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1724374
Bacillus Calmette-Guerin (BCG) and environmental mycobacteria divert Dendritic Cell functions interfering with the differentiation of precursors into competent APCs
Martino, A. (2006) · Cineca Institutional Research Information System (Tor Vergata University)

Authors: Lewinsohn, D. M., Alderson, M. R., Briden, A. L., Riddell, S. R., Reed, S. G., & Grabstein, K. H.
Affiliations: Infectious Disease Research Institute (US)
Corresponding author: Lewinsohn, David M.
ORCID: Lewinsohn, David M.
Alderson, Mark R.
Riddell, Stanley R.
Reed, Steven G.
Venue: The Journal of Experimental Medicine
Publisher: Rockefeller University Press
Published: 1998-05-18
Volume: 187
Issue: 10
Pages: 1633-1640
ISSN: 0022-1007 (ISSN-L)
1540-9538
DOI: 10.1084/jem.187.10.1633
PMC: PMC2212289
OpenAlex: W2111354206
Cited by: 165
References: 33
Citations by year: 2026: 2 · 2025: 3 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 2 · 2016: 6 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 6
FWCI: 16.05
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: cc-by-nc-sa
Locations: The Journal of Experimental Medicine (publishedVersion)
PubMed Central (publishedVersion, cc-by-nc-sa)
PubMed (publishedVersion)
Funders: National Heart, Lung, and Blood Institute (5T32 HL-07287, T32HL007287)
Topics: Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
Keywords: CD8+ T cells, Mycobacterium tuberculosis, tuberculosis, interferon-gamma, MHC class I restriction, MHC class Ib, antigen presentation, human immune response
MeSH terms: Acetylcysteine, Amino Acid Sequence, Animals, Chloroquine, Humans, Lymphocyte Cooperation, Molecular Sequence Data, Mycobacterium tuberculosis, Tuberculosis, Cysteine Proteinase Inhibitors, Antigen Presentation, CD8-Positive T-Lymphocytes, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Characterization of Human CD8+ T Cells Reactive with Mycobacterium tuberculosis–infected Antigen-presenting Cells

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks