The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Regulation of inflammatory responses by IL-17F
Open accessAbstract
Although interleukin (IL) 17 has been extensively characterized, the function of IL-17F, which has an expression pattern regulated similarly to IL-17, is poorly understood. We show that like IL-17, IL-17F regulates proinflammatory gene expression in vitro, and this requires IL-17 receptor A, tumor necrosis factor receptor–associated factor 6, and Act1. In vivo, overexpression of IL-17F in lung epithelium led to infiltration of lymphocytes and macrophages and mucus hyperplasia, similar to observations made in IL-17 transgenic mice. To further understand the function of IL-17F, we generated and analyzed mice deficient in IL-17F or IL-17. IL-17, but not IL-17F, was required for the initiation of experimental autoimmune encephalomyelitis. Mice deficient in IL-17F, but not IL-17, had defective airway neutrophilia in response to allergen challenge. Moreover, in an asthma model, although IL-17 deficiency reduced T helper type 2 responses, IL-17F–deficient mice displayed enhanced type 2 cytokine production and eosinophil function. In addition, IL-17F deficiency resulted in reduced colitis caused by dextran sulfate sodium, whereas IL-17 knockout mice developed more severe disease. Our results thus demonstrate that IL-17F is an important regulator of inflammatory responses that seems to function differently than IL-17 in immune responses and diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Fate-mapping studies using IL-17-fate reporter mice showed IL-23R-dependent differentiation of IL-17-producing cells into encephalitogenic IFNγ-producing Th1/Th17 cells”
From TH17 cell heterogeneity and its role in tissue inflammation (2023) · cites this paper as [76]
In the citing paper
“Use of cell fate reporter mice showed that T cells that initially express IL-17 (ex-Th17 cells) can subsequently express proinflammatory cytokines, including IFNγ and GM-CSF [38, 76].”
From TH17 cell heterogeneity and its role in tissue inflammation (2023) · cites this paper as [76]
In the citing paper
“Under inflammatory conditions, tissue Th17 cells have been reported to exhibit plastic changes in their effector programs.”
From TH17 cell heterogeneity and its role in tissue inflammation (2023) · cites this paper as [76]
In the citing paper
“In the absence of IL-23, Th17 cells lose the ability to up-regulate IFNγ and GM-CSF [76].”
From TH17 cell heterogeneity and its role in tissue inflammation (2023) · cites this paper as [76]
In the citing paper
“A key driver of the Th17 cell transition towards a pathogenic phenotype is the cytokine IL-23.”
From TH17 cell heterogeneity and its role in tissue inflammation (2023) · cites this paper as [76]
In the citing paper
“This conclusion is further supported by the findings that GM-CSF+ T cells co-express a great variety of other cytokines including IL-2, IL-3, IL-4, IL-6, IL-13, IL-17A, IL-22, IFNγ, and TNF [33, 36, 76, 175].”
From TH17 cell heterogeneity and its role in tissue inflammation (2023) · cites this paper as [76]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ivanov, I. I., McKenzie, B. S., Zhou, L., Tadokoro, C. E., Lepelley, A., Lafaille, J. J., Cua, D. J., & Littman, D. R. (2006) · Cell · doi:10.1016/j.cell.2006.07.035 · Cited by 5,145
Harrington, L. E., Hatton, R. D., Mangan, P. R., Turner, H., Murphy, T. L., Murphy, K. M., & Weaver, C. T. (2005) · Nature Immunology · doi:10.1038/ni1254 · Cited by 4,742
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y.-H., Wang, Y., Hood, L., Zhu, Z., Tian, Q., et al. (2005) · Nature Immunology · doi:10.1038/ni1261 · Cited by 4,265
Self-citationIL-23 drives a pathogenic T cell population that induces autoimmune inflammation
Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., Sedgwick, J. D., McClanahan, T., Kastelein, R. A., & Cua, D. J. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041257 · Cited by 4,099
Interleukin-17 Family Members and Inflammation
Kolls, J. K., & Lindén, A. (2004) · Immunity · doi:10.1016/j.immuni.2004.08.018 · Cited by 2,371
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
Zheng, Y., Danilenko, D. M., Valdez, P. A., Kasman, I. M., Eastham‐Anderson, J., Wu, J., & Ouyang, W. (2006) · Nature · doi:10.1038/nature05505 · Cited by 1,888
Zhu, Z., Homer, R., Wang, Z., Chen, Q., Geba, G. P., Wang, J., Zhang, Y., & Elias, J. A. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5909 · Cited by 1,732
Self-citationT Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
Yang, X. O., Pappu, B. P., Nurieva, R., Akimzhanov, A., Kang, H. S., Chung, Y., Ma, L., Shah, B., Panopoulos, A. D., Schluns, K. S., et al. (2008) · Immunity · doi:10.1016/j.immuni.2007.11.016 · Cited by 1,605
Self-citationSTAT3 Regulates Cytokine-mediated Generation of Inflammatory Helper T Cells
Yang, X. O., Panopoulos, A. D., Nurieva, R., Chang, S. H., Wang, D., Watowich, S. S., & Dong, C. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.c600321200 · Cited by 1,530
Self-citationYe, P., Rodriguez, F. H., Kanaly, S. T., Stocking, K. L., Schurr, J. R., Schwarzenberger, P. O., Oliver, P., Huang, W., Zhang, P., Zhang, J., et al. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.4.519 · Cited by 1,522
Flagged first, then by citations
Research works printed but not linked: 1
- 2006, Nat. Immunol., 7, 709
Cited by
Sorted by citations
Items 401–500 of 739
Dulek, D. E., Newcomb, D. C., Goleniewska, K., Cephus, J., Zhou, W., Reiss, S., Toki, S., Ye, F., Zaynagetdinov, R., Sherrill, T. P., et al. (2014) · Infection and Immunity · doi:10.1128/iai.00035-14 · Cited by 29
Role of microRNAs in immunity and organ transplantation
Spiegel, J. C., Lorenzen, J. M., & Thum, T. (2011) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399411002080 · Cited by 29
Kaul, M., Jarvis, P., Rozenberg, I., Kolbinger, F., Padova, F. D., Calonder, C., Espié, P., Rondeau, J., Cèbe, R., Huber, T., et al. (2020) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.17071 · Cited by 29
Takayanagi, Y., Osawa, S., Ikuma, M., Takagaki, K., Zhang, J., Hamaya, Y., Yamada, T., Sugimoto, M., Furuta, T., Miyajima, H., et al. (2012) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2012.02.007 · Cited by 29
IL-17C/IL-17RE Augments T Cell Function in Autoimmune Hepatitis
Huang, J., Yuan, Q., Zhu, H., Yin, L., Hong, S., Dong, Z., Jin, W., & Dong, C. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1600977 · Cited by 29
Self-citationMouse models in colon cancer, inferences, and implications
Kucherlapati, M. H. (2023) · iScience · doi:10.1016/j.isci.2023.106958 · Cited by 30
Vaccine-Induced Immunity Against Helicobacter pylori in the Absence of IL-17A
DeLyria, E. S., Nedrud, J. G., Ernst, P. B., Alam, M. S., Redline, R. W., Ding, H., Czinn, S. J., Xu, J., & Blanchard, T. G. (2011) · Helicobacter · doi:10.1111/j.1523-5378.2011.00839.x · Cited by 28
sPLA2-IIa Amplifies Ocular Surface Inflammation in the Experimental Dry Eye (DE) BALB/c Mouse Model
Wei, Y., Epstein, S. P., Fukuoka, S., Birmingham, N., Li, X.-M., & Asbell, P. A. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6350 · Cited by 28
Onac, I. A., Clarke, B. D., Tacu, C., Lloyd, M. E., Hajela, V., Batty, T., Thoroughgood, J., Smith, S., Irvine, H., Hill, D., et al. (2021) · Lara D. Veeken · doi:10.1093/rheumatology/keab193 · Cited by 28
Diseases that may benefit from manipulating the Th17 pathway
Miossec, P. (2009) · European Journal of Immunology · doi:10.1002/eji.200839088 · Cited by 28
Role of TH-17 Cells in Rheumatic and Other Autoimmune Diseases
Volin, M. V., & Shahrara, S. (2011) · Rheumatology Current Research · doi:10.4172/2161-1149.1000104 · Cited by 28
Fragile Treg cells: Traitors in immune homeostasis?
Song, X., Chen, R., Li, J., Zhu, Y., Jiao, J., Liu, H., Chen, Z., & Geng, J. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107297 · Cited by 29
Adamik, J., Henkel, M., Ray, A., Auron, P. E., Duerr, R. H., & Barrie, A. M. (2013) · Cytokine · doi:10.1016/j.cyto.2013.05.010 · Cited by 27
CD226 Attenuates Treg Proliferation via Akt and Erk Signaling in an EAE Model
Wang, N., Yi, H., Fang, L., Jin, J., Ma, Q., Shen, Y., Li, J., Liang, S., Xiong, J., Li, Z., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01883 · Cited by 28
Targeting Th17 cells in immune diseases
Dong, C. (2014) · Cell Research · doi:10.1038/cr.2014.92 · Cited by 27
Self-citationFerrucci, V., Asadzadeh, F., Collina, F., Siciliano, R., Boccia, A. S., Marrone, L., Spano, D., Carotenuto, M., Chiarolla, C. M., Martino, D. D., et al. (2020) · iScience · doi:10.1016/j.isci.2020.101938 · Cited by 26
Noll, J., Helk, E., Fehling, H., Bernin, H., Marggraff, C., Jacobs, T., Huber, S., Pelczar, P., Ernst, T., Ittrich, H., et al. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.01.013 · Cited by 27
CD8 + T Cell Immunity Is Compromised by Anti-CD20 Treatment and Rescued by Interleukin-17A
Vernengo, F. F., Beccaría, C. G., Furlan, C. L. A., Tosello, J., Almada, L., Serrán, M. G., Gazzoni, Y., Montes, C. L., Rodríguez, E. V. A., & Gruppi, A. (2020) · mBio · doi:10.1128/mbio.00447-20 · Cited by 25
Cho, M., Lee, J.-E., Lim, H., Shin, H., Khalmuratova, R., Choi, G., Kim, H. S., Choi, W. S., Park, Y.-J., Shim, I., et al. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.09.019 · Cited by 25
Regulation of intestinal immunity by dietary fatty acids
Qiu, J., Ma, Y., & Qiu, J. (2022) · Mucosal Immunology · doi:10.1038/s41385-022-00547-2 · Cited by 30
T helper type 17 pathway suppression by appendicitis and appendectomy protects against colitis
Cheluvappa, R., Luo, A. S., & Grimm, M. (2013) · Clinical & Experimental Immunology · doi:10.1111/cei.12237 · Cited by 25
Possible role for anisodamine in organophosphate poisoning
Eisenkraft, A., & Falk, A. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13486 · Cited by 25
Washino, T., Moroda, M., Iwakura, Y., & Aosai, F. (2012) · Infection and Immunity · doi:10.1128/iai.05680-11 · Cited by 26
Novel therapeutic targets along the Th17 pathway
Ouyang, W., Filvaroff, E. H., Hu, Y., & Grogan, J. L. (2009) · European Journal of Immunology · doi:10.1002/eji.200839105 · Cited by 26
Adult Non-Cystic Fibrosis Bronchiectasis Is Characterised by Airway Luminal Th17 Pathway Activation
Chen, A. C. –., Martin, M. L., Lourie, R., Rogers, G. B., Burr, L. D., Hasnain, S. Z., Bowler, S., McGuckin, M. A., & Serisier, D. J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119325 · Cited by 24
Shahid, A., & Bharadwaj, M. (2019) · Immunology Letters · doi:10.1016/j.imlet.2019.07.001 · Cited by 24
T helper subsets in allergic eye disease
Reyes, N. S., & Saban, D. R. (2014) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000088 · Cited by 24
Adult Onset Still's Disease and Autoinflammation
Efthimiou, P., Moorthy, L. N., Mavragani, C. P., Skokos, D., & Fautrel, B. (2012) · International Journal of Inflammation · doi:10.1155/2012/964751 · Cited by 24
Gupta, I., Sehgal, R., Kanwar, R. K., Punj, V., & Kanwar, J. R. (2014) · Nanomedicine · doi:10.2217/nnm.14.209 · Cited by 24
Combined Blockade of IL-17A and IL-17F May Prevent the Development of Experimental Colitis
McLean, L. P., Cross, R. K., & Shea‐Donohue, T. (2013) · Immunotherapy · doi:10.2217/imt.13.87 · Cited by 24
Antagonistic RNA aptamer specific to a heterodimeric form of human interleukin-17A/F
Adachi, H., Ishiguro, A., Hamada, M., Sakota, E., Asai, K., & Nakamura, Y. (2011) · Biochimie · doi:10.1016/j.biochi.2011.04.003 · Cited by 25
Niu, J., Guo, Y., Jing, G., Wang, H., Yang, L., Li, Y., Gao, Y., Wang, H., Li, A., Xu, X., et al. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202305042 · Cited by 23
Ho, A. W., Garg, A. V., Monin, L., Simpson-Abelson, M. R., Kinner, L. B., & Gaffen, S. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070168 · Cited by 25
Brodalumab-an IL-17RA monoclonal antibody for psoriasis and psoriatic arthritis
Bauer, E. M., Lucier, J. L., & Furst, D. E. (2015) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.1045410 · Cited by 23
Morrison, P. J., Ballantyne, S. J., Macdonald, S. J., Moore, J. W. J., Jenkins, D., Wright, J. F., Fouser, L. A., & Kullberg, M. C. (2015) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.08.015 · Cited by 23
Diagnostic and prognostic value of serum IL-23 in colorectal cancer
El‐Essawi, D. F., Alkady, M. M., & Ibrahim, I. M. (2019) · Arab Journal of Gastroenterology · doi:10.1016/j.ajg.2019.05.002 · Cited by 24
Gan, Y., Zhao, X., He, J., Liu, X., Li, Y., Sun, X., & Li, Z. (2017) · Journal of Immunology Research · doi:10.1155/2017/4768408 · Cited by 24
Targeting interleukin-17 as a novel treatment option for fibrotic diseases
Sisto, M., & Lisi, S. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm13010164 · Cited by 22
Asthma Phenotypes and Endotypes: Implications for Personalised Therapy
Dean, K., & Niven, R. M. (2017) · BioDrugs · doi:10.1007/s40259-017-0242-5 · Cited by 22
Guo, J., Zhang, Y., Sun, M., & Xu, L. (2022) · Inflammation · doi:10.1007/s10753-022-01678-1 · Cited by 22
Wu, D., Zhang, X. Y., Zimmerly, K. M., Wang, R., Wang, C., Hunter, R., Wu, X. Y., Campen, M. J., Liu, M., & Yang, X. O. (2023) · Mucosal Immunology · doi:10.1016/j.mucimm.2023.05.007 · Cited by 21
Self-citationSerum IL-17F combined with VEGF as potential diagnostic biomarkers for oral squamous cell carcinoma
Ding, L., Hu, E., Xu, Y., Huang, X., Zhang, D., Li, B., Hu, Q., Ni, Y., & Hou, Y. (2015) · Tumor Biology · doi:10.1007/s13277-014-2867-z · Cited by 22
The Role of Interleukin-17A in Colorectal Tumorigenesis
Shi, Y., Lin, H., Cui, J., Qi, H., Florholmen, J., Liu, Z., & Cui, G. (2013) · Cancer Biotherapy and Radiopharmaceuticals · doi:10.1089/cbr.2012.1396 · Cited by 22
Ishioka, T., Kimura, H., Kita, H., Obuchi, M., Hoshino, H., Noda, M., Nishina, A., Kozawa, K., & Katô, M. (2010) · Cell Biology International · doi:10.1042/cbi20100255 · Cited by 22
Cytokine crowdsourcing: multicellular production of TH17-associated cytokines
Busman‐Sahay, K., Walrath, T., Huber, S., & O’Connor, W. (2014) · Journal of Leukocyte Biology · doi:10.1189/jlb.3ru0814-386r · Cited by 24
Inflammatory Dietary Pattern, IL-17F Genetic Variant, and the Risk of Colorectal Cancer
Cho, Y. A., Lee, J., Oh, J. H., Chang, H. J., Sohn, D. K., Shin, A., & Kim, J. (2018) · Nutrients · doi:10.3390/nu10060724 · Cited by 22
Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway
Sun, H., Tang, C., Chung, S.-H., Ye, X.-Q., Makusheva, Y., Han, W., Kubo, M., Shichino, S., Ueha, S., Matsushima, K., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111158 · Cited by 21
Reduced small‐intestinal injury induced by indomethacin in interleukin‐17A‐deficient mice
Yamada, S., Naito, Y., Takagi, T., Mizushima, K., Hirai, Y., Horie, R., Fukumoto, K., Inoue, K., Harusato, A., Yoshida, N., et al. (2010) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2010.06496.x · Cited by 21
Folestad, A., Ålund, M., Asteberg, S., Fowelin, J., Aurell, Y., Göthlin, J., & Cassuto, J. (2015) · Journal of Foot and Ankle Research · doi:10.1186/s13047-015-0096-3 · Cited by 21
Functional Plasticity of Th17 Cells: Implications in Gastrointestinal Tract Function
Garrido‐Mesa, N., Algieri, F., Rodríguez‐Nogales, A., & Gálvez, J. (2013) · International Reviews of Immunology · doi:10.3109/08830185.2013.834899 · Cited by 22
Aslanıpour, B., Gülcemal, D., Nalbantsoy, A., Yusufoglu, H. S., & Bedіr, E. (2017) · Phytochemistry Letters · doi:10.1016/j.phytol.2017.05.028 · Cited by 21
Neuroimmune communication of the cholinergic system in gut inflammation and autoimmunity
Halder, N., Yadav, S., & Lal, G. (2024) · Autoimmunity Reviews · doi:10.1016/j.autrev.2024.103678 · Cited by 21
Review: New Anti-Cytokines for IBD: What is in the Pipeline?
Scharl, M. M., Vavricka, S. R., & Rogler, G. (2013) · Current Drug Targets · doi:10.2174/13894501113149990159 · Cited by 19
Shirzad, H., Bagheri, N., Azadegan‐Dehkordi, F., Zamanzad, B., Izadpanah, E., Abdi, M., Ramazani, G., Sanei, M. H., Ayoubian, H., Ahmadi, A., et al. (2015) · PubMed · Cited by 20
Merkley, S. D., Goodfellow, S. M., Guo, Y. P., Wilton, Z. E. R., Byrum, J. R., Schwalm, K. C., Dinwiddie, D. L., Gullapalli, R. R., Deretic, V. P., Hernández, A. J., et al. (2021) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjab144 · Cited by 20
Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock
Shimura, E., Shibui, A., Narushima, S., Nambu, A., Yamaguchi, S., Akitsu, A., Leonard, W. J., Iwakura, Y., Matsumoto, K., Suto, H., et al. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.09.004 · Cited by 22
The IL17F and IL17RA Genetic Variants Increase Risk of Cerebral Malaria in Two African Populations
Marquet, S., Conte, I. L., Poudiougou, B., Argiro, L., Cabantous, S., Dessein, H., Burté, F., Oumar, A. A., Brown, B. J., Traore, A., et al. (2015) · Infection and Immunity · doi:10.1128/iai.00671-15 · Cited by 19
Autotaxin and lysophosphatidic acid signalling in lung pathophysiology
Magkrioti, C. (2013) · World Journal of Respirology · doi:10.5320/wjr.v3.i3.77 · Cited by 20
Muzaki, A. R. B. M., Soncin, I., Setiagani, Y. A., Sheng, J., Tetlak, P., Karjalainen, K., & Ruedl, C. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1701053 · Cited by 21
Bimekizumab for the treatment of psoriatic disease
Natsis, N. E., & Gottlieb, A. B. (2018) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2018.1538351 · Cited by 20
Fu, S.-H., Lin, M.-H., Yeh, L.-T., Wang, Y.-L., Chien, M.-W., Lin, S.-H., Chang, D., & Sytwu, H. (2014) · Gut · doi:10.1136/gutjnl-2013-306585 · Cited by 22
Zhang, F., Wang, Z., Li, M., Lan, Y.-T., Chen, Y., & Wang, C. (2015) · International Immunopharmacology · doi:10.1016/j.intimp.2015.07.023 · Cited by 20
Ma, X., Hu, J., Yu, Y., Wang, C., Gu, Y., Cao, S., Huang, X., Wen, Y., Zhao, Q., Wu, R. J., et al. (2021) · Scientific Reports · doi:10.1038/s41598-020-79642-y · Cited by 19
Genetics and Innate and Adaptive Immunity in IBD
Zanello, G., Kevans, D., Goethel, A., Silverberg, M. S., Tyler, A. D., & Croitoru, K. (2014) · Nestlé Nutrition Institute Workshop series · doi:10.1159/000360676 · Cited by 19
Sabat, R., Witte, E., Witte, K., & Wolk, K. (2012) · Springer eBooks · doi:10.1007/978-3-0348-0522-3_2 · Cited by 22
Roles of IL-22 in Allergic Airway Inflammation
Hirose, K., Takahashi, K., & Nakajima, H. (2013) · Journal of Allergy · doi:10.1155/2013/260518 · Cited by 19
Cheluvappa, R. (2014) · International Journal of Colorectal Disease · doi:10.1007/s00384-014-1936-5 · Cited by 19
You, Q., Sun, G., Wang, N., Shen, J., & Wang, Y. (2009) · Journal of Surgical Research · doi:10.1016/j.jss.2009.01.019 · Cited by 19
Self-citationCheluvappa, R. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy332 · Cited by 19
Is Psoriasis Treatment a Risk Factor for Inflammatory Bowel Disease?
Nehring, P., & Przybyłkowski, A. M. (2020) · Pharmaceutical Medicine · doi:10.1007/s40290-020-00340-1 · Cited by 19
Zhou, C., Wu, D., Jawale, C. V., Li, Y., Biswas, P. S., McGeachy, M. J., & Gaffen, S. L. (2021) · Cytokine · doi:10.1016/j.cyto.2021.155715 · Cited by 20
IL-17F Induces CCL20 in Bronchial Epithelial Cells
Nozato, K., Fujita, J., Kawaguchi, M., Ohara, G., Morishima, Y., Ishii, Y., Huang, S., Kokubu, F., Satoh, H., & Hizawa, N. (2011) · Journal of Allergy · doi:10.1155/2011/587204 · Cited by 19
Physiological roles of human interleukin‐17 family
Liu, Y., Ouyang, Y., You, W., Liu, W., Cheng, Y., Mai, X., & Shen, Z. (2023) · Experimental Dermatology · doi:10.1111/exd.14964 · Cited by 22
Pathogenesis of Psoriasis: The Role of Pro-Inflammatory Cytokines Produced by Keratinocytes
Balato, A., Balato, N., Megna, M., Schiattarella, M., Lembo, S., & Ayal, F. (2012) · InTech eBooks · doi:10.5772/26163 · Cited by 18
IL-17A Mediates Early Post-Transplant Lesions after Heterotopic Trachea Allotransplantation in Mice
Lemaitre, P. H., Vokaer, B., Charbonnier, L., Iwakura, Y., Estenne, M., Goldman, M., Léo, O., Remmelink, M., & Moine, A. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070236 · Cited by 19
Epitope‐Targeted Macrocyclic Peptide Ligand with Picomolar Cooperative Binding to Interleukin‐17F
Lai, B. T., Wilson, J. A., Loredo, J. M., Pitram, S. M., LaBerge, N. A., Heath, J. R., & Agnew, H. D. (2018) · Chemistry - A European Journal · doi:10.1002/chem.201704752 · Cited by 18
Guo, T., Huo, Y., Zhu, W., Xu, F., Liu, C., Liu, N., Cao, M., Cui, B., & Ning, G. (2012) · Gene · doi:10.1016/j.gene.2012.10.021 · Cited by 18
Songhet, P., Barthel, M., Röhn, T. A., Maele, L. V., Cayet, D., Sirard, J., Bachmann, M. F., Köpf, M., & Hardt, W. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013804 · Cited by 18
Jia, R., Zheng, H., Li, S., Chen, W., Yang, Y., Wu, H., Chen, H., Qin, S., & Huang, S. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.155779 · Cited by 17
Yates, T. H., Cooperman, S. R., Shofler, D. W., & Agrawal, D. K. (2020) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2020.1804869 · Cited by 17
Liu, J., Liu, S., Cao, H., Shi, B., Li, Q., Shan, J., Yuan, J., & Lin, J. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/6461560 · Cited by 17
Interleukin-17 serum levels and TLR4 polymorphisms in ulcerative colitis.
Mohammadi, M., Zahedi, M. J., Nikpoor, A. R., Baneshi, M. R., & Hayatbakhsh, M. M. (2013) · PubMed · doi:10.22034/iji.2013.16812 · Cited by 17
Jeong, E. M., Son, Y. H., Choi, Y., Kim, J. H., Lee, J.-H., Cho, S., & Kim, I. G. (2016) · Experimental & Molecular Medicine · doi:10.1038/emm.2016.95 · Cited by 17
Hoang, C. T., Hong, Y., Truong, A. D., Lee, J., Lee, K., & Hong, Y. H. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.04.010 · Cited by 17
Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water
Li, X., Li, L., Liu, X., Wu, J., Sun, X., Li, Z., Geng, Y., Liu, F., & Zhou, Y. (2019) · Current Molecular Medicine · doi:10.2174/1566524019666190321113544 · Cited by 17
Mechanistic Insights into the Roles of the IL-17/IL-17R Families in Pancreatic Cancer
Chen, Z., Qiao, S., Liu, Y., Sun, M., Li, B., Lü, A., & Li, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713539 · Cited by 17
Inhibition of RORγt activity and Th17 differentiation by a set of novel compounds
Ding, Q., Zhao, M., Bai, C., Yu, B., & Huang, Z. (2015) · BMC Immunology · doi:10.1186/s12865-015-0097-9 · Cited by 16
Targeting the IL-23/IL-17 Pathway in Psoriasis: the Search for the Good, the Bad and the Ugly
Mylle, S., Grine, L., Speeckaert, R., Lambert, J., & van Geel, N. (2018) · American Journal of Clinical Dermatology · doi:10.1007/s40257-018-0366-5 · Cited by 16
The IL-23/IL-17A axis in spondyloarthritis: therapeutics informing pathogenesis?
Siebert, S., McGucken, A., & McInnes, I. B. (2020) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000719 · Cited by 16
So, J.-B., Silver, P., Jittayasothorn, Y., Mattapallil, M., Chan, C.-C., Horai, R., & Caspi, R. (2020) · Journal of Autoimmunity · doi:10.1016/j.jaut.2020.102507 · Cited by 18
IL-17-related signature genes linked to human necrotizing enterocolitis
Tremblay, É., Ferretti, E., Babakissa, C., Burghardt, K. M., Levy, E. H., & Beaulieu, J. (2021) · BMC Research Notes · doi:10.1186/s13104-021-05489-9 · Cited by 16
Corral‐Jara, K. F., Chauvin, C., Abou-Jaoudé, W., Grandclaudon, M., Naldi, A., Soumelis, V., & Thieffry, D. (2021) · Molecular Biomedicine · doi:10.1186/s43556-021-00034-3 · Cited by 16
Vargas, F. V. V., Rivera-Valdes, J. J., Alvarado‐Navarro, A., Huerta-Olvera, S. G., Macías‐Barragán, J., Martínez‐López, E., & Graciano‐Machuca, O. (2021) · Inflammation Research · doi:10.1007/s00011-021-01514-6 · Cited by 16
Th17 Cells Demonstrate Stable Cytokine Production in a Proallergic Environment
Glosson, N. L., Sehra, S., Stritesky, G. L., Yu, Q., Awe, O., Pham, D., Bruns, H. A., & Kaplan, M. H. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1401202 · Cited by 14
Seventeen in Crohn's disease: less prime than we thought?
Raine, T., & Kaser, A. (2012) · Gut · doi:10.1136/gutjnl-2012-302525 · Cited by 16
Cholera Toxin Directly Enhances IL-17A Production from Human CD4+ T Cells
Tsai, H., & Wu, R. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301079 · Cited by 17
IL-17F induces IL-6 via TAK1-NFκB pathway in airway smooth muscle cells
Nakajima, M., Kawaguchi, M., Ota, K., Fujita, J., Matsukura, S., Huang, S.-K., Morishima, Y., Ishii, Y., Satoh, H., Sakamoto, T., et al. (2017) · Immunity Inflammation and Disease · doi:10.1002/iid3.149 · Cited by 17
Aslanıpour, B., Gülcemal, D., Nalbantsoy, A., Yusufoglu, H. S., & Bedіr, E. (2017) · Fitoterapia · doi:10.1016/j.fitote.2017.08.008 · Cited by 16
Miljkovic, D., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00898 · Cited by 17
TH17 cell: a double-edged sword in the development of inflammatory bowel disease
Wen, Y., Wang, H., Tian, D., & Wang, G. (2024) · Therapeutic Advances in Gastroenterology · doi:10.1177/17562848241230896 · Cited by 16
Metadata
- Authors
- Yang, X. O., Chang, S. H., Park, H., Nurieva, R., Shah, B., Acero, L., Wang, Y.-H., Schluns, K. S., Broaddus, R. R., Zhu, Z., & Dong, C.
- Affiliations
- The University of Texas MD Anderson Cancer Center (US)
- 1Department of Immunology
- University of Washington (US)
- Johns Hopkins University (US)
- ORCID
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 2008-04-14
- Volume
- 205
- Issue
- 5
- Pages
- 1063-1075
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- PMC
- PMC2373839
- OpenAlex
- W2110264653
- Cited by
- 739
- References
- 47
- Citations by year
- 2026: 6 · 2025: 14 · 2024: 18 · 2023: 27 · 2022: 40 · 2021: 31 · 2020: 33 · 2019: 27 · 2018: 38 · 2017: 45 · 2016: 39 · 2015: 54 · 2014: 56 · 2013: 56 · 2012: 54
- FWCI
- 28.07
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by-nc-sa
- Locations
- The Journal of Experimental Medicine (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Life Sciences › Immunology and Microbiology › Immunology › Cytokine Signaling Pathways and Interactions
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- IL-17F, IL-17, inflammation, IL-17 receptor A, TRAF6, Act1, pro-inflammatory gene expression, lung epithelium, experimental autoimmune encephalomyelitis, airway neutrophilia, allergen challenge, asthma, Th2 immune response, eosinophils, colitis, dextran sulfate
- MeSH terms
- Animals, Cell Line, Fibroblasts, Homeostasis, Inflammation, Lymphocyte Activation, Mice, Transgenic, T-Lymphocytes, Transfection, CD4-Positive T-Lymphocytes, Mice, Knockout, Reverse Transcriptase Polymerase Chain Reaction, Interleukin-17, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
