Cited by 626Gut microbiota and healthHematopoietic Stem Cell TransplantationProbiotics and Fermented Foods

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

Open access

Jenq, Robert R., Ubeda, Carles, Taur, Ying, Menezes, Clarissa C., Khanin, Raya, Dudakov, Jarrod A., Liu, Chen, West, Mallory L., Singer, Natalie V., Equinda, Michele J., Gobourne, Asia, Lipuma, Lauren, Young, Lauren F., Smith, Odette M., Ghosh, Arnab, Hanash, Alan M., Goldberg, Jenna D., Aoyama, Kazutoshi, Blazar, Bruce R., Pamer, Eric G., R.M. van den Brink, Marcel·2012·Journal of Experimental Medicine

DOI 10.1084/jem.20112408PMC PMC3348096

Open this paper in CoChat — free account

Abstract

Despite a growing understanding of the link between intestinal inflammation and resident gut microbes, longitudinal studies of human flora before initial onset of intestinal inflammation have not been reported. Here, we demonstrate in murine and human recipients of allogeneic bone marrow transplantation (BMT) that intestinal inflammation secondary to graft-versus-host disease (GVHD) is associated with major shifts in the composition of the intestinal microbiota. The microbiota, in turn, can modulate the severity of intestinal inflammation. In mouse models of GVHD, we observed loss of overall diversity and expansion of Lactobacillales and loss of Clostridiales. Eliminating Lactobacillales from the flora of mice before BMT aggravated GVHD, whereas reintroducing the predominant species of Lactobacillus mediated significant protection against GVHD. We then characterized gut flora of patients during onset of intestinal inflammation caused by GVHD and found patterns mirroring those in mice. We also identified increased microbial chaos early after allogeneic BMT as a potential risk factor for subsequent GVHD. Together, these data demonstrate regulation of flora by intestinal inflammation and suggest that flora manipulation may reduce intestinal inflammation and improve outcomes for allogeneic BMT recipients.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1084/jem.20112408

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities
Schloss, P. D., Westcott, S. L., Ryabin, T., Hall, J. R., Hartmann, M., Hollister, E. B., Lesniewski, R. A., Oakley, B. B., Parks, D. H., Robinson, C. J., et al. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.01541-09 · Cited by 21,481
Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy
Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 20,145
Measuring biological diversity
Magurran, A. E. (2004) · Choice Reviews Online · doi:10.5860/choice.42-1547 · Cited by 6,617
Gut microbiota in health and disease
Sekirov, I., Russell, S. L., Antunes, L. C. M., & Finlay, B. B. (2010) · Physiological Reviews · doi:10.1152/physrev.00045.2009 · Cited by 4,182
Human nutrition, the gut microbiome and the immune system
Kau, A. L., Ahern, P. P., Griffin, N. W., Goodman, A. L., & Gordon, J. I. (2011) · Nature · doi:10.1038/nature10213 · Cited by 2,588
Graft-versus-host disease
Ferrara, J. L. M., Levine, J. E., Reddy, P. R., & Holler, E. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60237-3 · Cited by 2,508
The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
Dethlefsen, L., Huse, S., Sogin, M. L., & Relman, D. A. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060280 · Cited by 2,361
Intestinal homeostasis and its breakdown in inflammatory bowel disease
Maloy, K. J., & Powrie, F. M. (2011) · Nature · doi:10.1038/nature10208 · Cited by 1,911
UniFrac – An online tool for comparing microbial community diversity in a phylogenetic context
Lozupone, C., Hamady, M., & Knight, R. D. (2006) · BMC Bioinformatics · doi:10.1186/1471-2105-7-371 · Cited by 1,454
An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin
Cooke, K., Kobzik, L., Martin, T., Brewer, J., Delmonte, J., Crawford, J., & Ferrara, J. (1996) · Blood · doi:10.1182/blood.v88.8.3230.bloodjournal8883230 · Cited by 967

Flagged first, then by citations

Show all 37 references

Sorted by citations

Items 501–600 of 624

Beyond steroids: A systematic review and proposed solutions to managing acute graft-versus-host disease in adolescents and young adults
Friend, B. D., & Schiller, G. J. (2021) · Blood Reviews · doi:10.1016/j.blre.2021.100886 · Cited by 3
Helminth Infections and Gut Microbiota: The Futuristic Study of Pathogen Virulence and Gut Ecosystem
Biswal, D. (2016) · Journal of Molecular Biomarkers & Diagnosis · doi:10.4172/2155-9929.1000283 · Cited by 3
Role of the microbiota in cancer growth and necrosis: the challenges and opportunities of bacteriotherapy for cancer and its complications
Pan, W. D., & Kang, Y. (2017) · Reviews in Medical Microbiology · doi:10.1097/mrm.0000000000000120 · Cited by 3
CD8+CD161hi T cells are associated with acute graft-versus-host disease after haploidentical hematopoietic stem cell transplantation
Hong, Y., Liu, L., Chang, Y., Wang, Y., Zhang, X., Xu, L., Huang, X., & Zhao, X. (2020) · Bone Marrow Transplantation · doi:10.1038/s41409-020-0842-4 · Cited by 3
Optimal GVHD Prophylaxis
Elmariah, H., & Bolaños‐Meade, J. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-84988-6_5 · Cited by 2
Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs
Han, J., Lee, D., Jeong, S., Yun, J., Kang, S., Jang, S., Lee, E., Baek, J. H., Jeon, C. O., & Bae, J. (2025) · Advanced Science · doi:10.1002/advs.202415982 · Cited by 3
Consensus guidelines for patient and carer education on neutropenic fever
Jessop, S., Harding, E. L., Beaumont, S., Hickman, J., Joyce, T., Chee, L. C. Y., Fernando, S. S., Vasilunas, N., Luen, S. J., Boan, P., et al. (2025) · Internal Medicine Journal · doi:10.1111/imj.70252 · Cited by 2
The gut microbiome in graft-versus-host disease: mechanisms of immune modulation and therapeutic approaches
Moses, A. B., & Yeh, A. C. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2631224 · Cited by 2
The Gut Microbiota in Hematologic Malignancies: Mechanisms, Clinical Associations, and Translational Opportunities
Caserta, S., Martino, E. A., Skafi, M., Vigna, E., Bruzzese, A., Amodio, N., Fiorillo, M., Lucia, E., D’Arrigo, G., Olivito, V., et al. (2026) · Nutrients · doi:10.3390/nu18091400 · Cited by 2
The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation
Hao, W., Stocker, N., Gaugler, B., Mohty, M., & Malard, F. (2026) · American Journal of Hematology · doi:10.1002/ajh.70360 · Cited by 2
Stool can soften GVHD
Hazenberg, M. D. (2018) · Blood · doi:10.1182/blood-2018-10-878652 · Cited by 2
Terapia Nutricional de Pacientes com Câncer Infantojuvenil submetidos a Transplante de Células-Tronco Hematopoiéticas
Garófolo, A., & Nakamura, C. H. (2019) · Revista Brasileira de Cancerologia · doi:10.32635/2176-9745.rbc.2018v64n3.43 · Cited by 2
Deciphering the role of the major histocompatibility complex, the intestinal microbiome and metabolites in the pathogenesis of acute graft-versus-host disease
Wenger, V., & Zeiser, R. (2024) · Best Practice & Research Clinical Haematology · doi:10.1016/j.beha.2024.101567 · Cited by 2
Intestinal microbiome and myelodysplastic syndromes: Current state of knowledge and perspectives for future
Simunic, M., McGraw, K. L., Pavletic, S. Z., & Rashidi, A. (2024) · Seminars in Hematology · doi:10.1053/j.seminhematol.2024.10.006 · Cited by 4
Understanding gut Microbiome changes in Korean children, adolescents, and young adults with hematologic malignancies
Park, M., Jung, J., Lee, J. A., Lee, E.-Y., Lee, H., Eom, H., & Park, H. J. (2025) · Annals of Hematology · doi:10.1007/s00277-025-06293-2 · Cited by 2
Microbiome and Diseases: Graft-Versus-Host Disease
Weber, D., & Holler, E. (2018) · Springer eBooks · doi:10.1007/978-3-319-90545-7_13 · Cited by 2
Innate Immunity at Mucosal Surfaces
Fujimoto, K., & Uematsu, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-811924-2.00006-7 · Cited by 2
An infectious diseases perspective on the microbiome and allogeneic stem cell transplant
Smibert, O. C., Trubiano, J. A., Slavin, M. A., & Kwong, J. C. (2020) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000683 · Cited by 2
Overexpression of S100A9 in donor T cells is associated with reconstitution of gut microbiota and outcome of allogeneic hematopoietic stem cell transplantation
Kim, S., Lim, S., Razmkhah, F., & Choi, J. (2023) · Blood Research · doi:10.5045/br.2023.2022238 · Cited by 2
The distribution of intestinal flora after hematopoietic stem cell transplantation in children
Tong, L., Meng, Y., Zhang, L., Yu, J. Z., & Dou, Y. (2023) · Pediatric Transplantation · doi:10.1111/petr.14678 · Cited by 2
Innate lymphoid cells in treatment-induced gastrointestinal pathogenesis
Omar, S. Z., Blom, B., & Hazenberg, M. D. (2020) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000499 · Cited by 2
Assessing Engraftment Following Fecal Microbiota TransplantPreprint
Herman, C., Barker, B. M., Bartelli, T. F., Chandra, V., Krajmalnik‐Brown, R., Jewell, M., Li, L., Liao, C., McAllister, F. M., Nirmalkar, K., et al. (2024) · PubMed · doi:10.48550/arxiv.2404.07325 · Cited by 2
Effects of obesity and weight-loss surgery shift the microbiome and impact alloimmune responses
Zhou, H., & Tullius, S. G. (2021) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000920 · Cited by 1
Investigating the effects of radiation, T cell depletion, and bone marrow transplantation on murine gut microbiota
Kreisinger, J., Dooley, J., Singh, K. N., Čížková, D., Schmiedová, L., Bendová, B., Liston, A., & Moudrá, A. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1324403 · Cited by 1
Gut Microbiome and its Impact on Outcomes following Hematopoietic Stem Cell Transplantation: a Comprehensive Review
Arjmand, B., Badamchizadeh, S., Mehran, P., Sarvari, M., Alavi-Moghadam, S., Arjmand, R., Rezaei–Tavirani, M., Janbabaei, G., Vaezi, M., & Larijani, B. A. (2025) · Stem Cell Reviews and Reports · doi:10.1007/s12015-025-10958-w · Cited by 1
Recent advances in the pathophysiology of acute and chronic graft-versus-host disease
Takahashi, S., & Hashimoto, D. (2026) · International Journal of Hematology · doi:10.1007/s12185-026-04177-3 · Cited by 1
The intestinal microbiota as a key modulator of acute graft-versus-host disease
Paredes, J. E., Schmiester, M., Jenq, R. R., & van den Brink, M. R. M. (2026) · Nature reviews. Cancer · doi:10.1038/s41568-026-00910-6 · Cited by 2
Self-citation
Immune interplay between sepsis and haematological malignancies
Pons, S., Grosset, M., Touze, E., & Zafrani, L. (2026) · Intensive Care Medicine Experimental · doi:10.1186/s40635-026-00904-6 · Cited by 1
Th17 Mediated Alloreactivity Is Facilitated by the Pre-Transplant Microbial Burden of the Recipient
Klimczak, A., & Lange, A. (2012) · Bone Marrow Research · doi:10.1155/2012/960280 · Cited by 1
Current understanding of the pathophysiology and management of acute graft versus host disease.
Maeda, Y. (2013) · Journal of Hematopoietic Cell Transplantation · doi:10.7889/hct.2.12 · Cited by 1
Microbiome in Transplantation
Taur, Y. (2016) · Springer eBooks · doi:10.1007/978-3-319-28797-3_51 · Cited by 1
Self-citation
Gut Microbiota in Graft-versus-Host Disease
Kim, Y. (2016) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2016.46.4.307 · Cited by 1
[Advances in intestinal microbiota and graft versus host disease].
Lyu, M., & Han, M. (2017) · PubMed Central · doi:10.3760/cma.j.issn.0253-2727.2017.12.019 · Cited by 1
[How I treat gastrointestinal tract acute graft versus host disease with fecal microbiota transplantation].
Tang, X., & Wu, D. P. (2022) · PubMed Central · doi:10.3760/cma.j.issn.0253-2727.2022.05.003 · Cited by 1
The inflammasome in graft-versus-host disease
Hamarsheh, S., & Zeiser, R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00005-0 · Cited by 1
Gut microbiome in allogeneic HCT survivors: The insults are gone but the damage lingers
van Lier, Y. F., & Hazenberg, M. D. (2023) · British Journal of Haematology · doi:10.1111/bjh.18653 · Cited by 1
Interplay between gut microbiota in immune homeostasis and inflammatory diseases
Tiwari, N., Suri, M., Upadhyay, J., Ansari, M. N., & Samad, A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99988-5.00016-4 · Cited by 1
New insights about immune populations in gastrointestinal GvHD
Hayase, E., & Jenq, R. R. (2023) · Cell Reports Medicine · doi:10.1016/j.xcrm.2023.101126 · Cited by 1
Self-citation
Interleukine 22
Gaugler, B., Lamarthée, B., Couturier, M., & Saas, P. (2013) · médecine/sciences · doi:10.1051/medsci/2013296008 · Cited by 1
Microbiome: Its Impact Is Being Revealed!
El‐Jurdi, N., Lima, M. J. G. D., Lazarus, H. M., & Ghannoum, M. A. (2017) · Current Clinical Microbiology Reports · doi:10.1007/s40588-017-0063-9 · Cited by 1
Le butyrate, un médiateur métabolique bactérien salutaire pour la réaction du greffon contre l’hôte
Bisaccia, J., & Soudja, S. M. (2017) · médecine/sciences · doi:10.1051/medsci/20173310016 · Cited by 1
Microbes and Their Metabolites Correlate with Hematopoietic Stem Cell Transplantation Outcomes?
Riwes, M. M., & Reddy, P. R. (2018) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2018.11.006 · Cited by 1
Microbiota and Graft‐versus Host disease: a double‐edged sword
Holler, E., & Weber, D. (2019) · HemaSphere · doi:10.1097/hs9.0000000000000204 · Cited by 1
Diagnostic and Therapeutic Uses of the Microbiome in the Field of Oncology
Anipindi, M., & Bitetto, D. (2022) · Cureus · doi:10.7759/cureus.24890 · Cited by 1
GUT MICROBIOTA EFFECTS IN HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS
Gürer, E. E., Oğuz, F. S., Beşışık, S. K., Aktaş, Z., Gülbaş, Z., Öncül, M., & Sezerman, O. U. (2022) · Journal of Istanbul Faculty of Medicine / İstanbul Tıp Fakültesi Dergisi · doi:10.26650/iuitfd.1027106 · Cited by 1
Microbes and cancer geography: can we exploit recent lessons from the gut system to oral cancer context?
Garlet, G. P., & Santos, C. F. (2014) · Journal of Applied Oral Science · doi:10.1590/1678-77572014ed004 · Cited by 1
Compte rendu
D’Aveni, M. (2013) · Hématologie · doi:10.1684/hma.2013.0807 · Cited by 1
Specific gut microbiome members are associated with distinct immune markers in allogeneic hematopoietic stem cell transplantationPreprint
Ingham, A. C., Kielsen, K., Cilieborg, M. S., Lund, O., Holmes, S., Aarestrup, F. M., Müller, K., & Pamp, S. J. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/590893 · Cited by 1
Fecal Microbiota Transplantation for Grade IV Steroid Refractory GI-GvHD: Interim Results a Non-randomized, Open-label, Phase 1 Clinical StudyPreprint
Zhao, Y., Li, X.-W., Zhou, Y., Ma, X., Chen, F., Hu, X.-H., Jin, S. L., He, X., Gao, J., Zhu, B., et al. (2020) · doi:10.21203/rs.3.rs-29647/v1 · Cited by 1
Distance Assisted Recursive TestingPreprint
Li, X., Sung, A. D., & Xie, J. (2021) · arXiv (Cornell University) · doi:10.48550/arxiv.2103.11085 · Cited by 1
Microbiota long-term dynamics and prediction of acute graft-versus-host-disease in pediatric allogeneic stem cell transplantationPreprint
Ingham, A. C., Kielsen, K., Mordhorst, H., Ifversen, M., Aarestrup, F. M., Müller, K., & Pamp, S. J. (2021) · Research Square · doi:10.21203/rs.3.rs-258775/v1 · Cited by 1
Overview of Hematopoietic Cell Transplantation Immunology
Martin, P. J., & Shlomchik, W. D. (2015) · Wiley eBooks · doi:10.1002/9781118416426.ch9 · Cited by 1
The role of citrulline in patients following hematopoietic stem cell transplantation
Herbers, A. H. E. (2015) · Radboud Repository (Radboud University)
Gut bugs and grafts
Bird, L. (2012) · Nature reviews. Immunology · doi:10.1038/nri3236
IMMUNE REPERTOIRE DIVERSITY IN ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS IMPLICATIONS FOR INFECTIONS AND THE GRAFT VERSUS LEUKEMIA EFFECT
Björklund, A. T. (2014) · Figshare
Inflammation and Antimicrobial Defense in the Intestine
Caballero, S., & Pamer, E. G. (2015)
Self-citation
Editorial Commentary: The Gut Microbiota Strikes Again
Poutsiaka, D. D. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ292
A specific component of the intestinal microbiota exacerbates the severity of allergic asthma
Burgess, S. L. (2013) · OhioLink ETD Center (Ohio Library and Information Network)
Recent insights to the mechanisms of graft-versus-host disease.
Koyama, M., & Hill, G. (2016) · [Rinsho ketsueki] The Japanese journal of clinical hematology · doi:10.11406/rinketsu.57.2169
Early Post-Transplant Interval
Abutalib, S. A. (2017) · Cambridge University Press eBooks · doi:10.1017/9781316335727.013
Progress Treating Acute Graft-versus-Host Disease?
Holler, E. (2017) · Cambridge University Press eBooks · doi:10.1017/9781316335727.014
Flies to Humans - Humans to Flies: A Virtuous Circle of Colorectal Cancer Prevention
Apidianakis, Y. (2017) · Archives of Clinical Gastroenterology · doi:10.17352/2455-2283.000038
The Impact of the Microbiome on Outcomes of Stem Cell Transplant
Jenq, R. R. (2017) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/j.clml.2017.08.028
Self-citation
Special Care of Blood and Marrow Hematopoietic Cell Transplant Recipient
Abutalib, S. A., & Lazarus, H. M. (2017) · Springer eBooks · doi:10.1007/978-3-319-64263-5_57
Human Milk to Prevent and Heal Gastrointestinal Tract Injury in Children After Bone Marrow Transplantation
Davies, S. M. (2018) · Breastfeeding Medicine · doi:10.1089/bfm.2018.29078.smd
Persisters of B. burgdorferi, the causative agent of Lyme disease
Sharma, B. (2016) · doi:10.17760/d20213076
ST2/MYD88 signaling is a therapeutic target alleviating murine acute graft-versus-host disease sparing T regulatory cell function
Griesenauer, B. (2018) · IUScholarWorks (Indiana University) · doi:10.7912/c2sk9v
Microbiome and Allogeneic Hematopoietic Stem Cell Transplantation
Chilkulwar, A. R., Weber, D., Jenq, R. R., & Holler, E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812630-1.00009-8
Self-citation
The Microbiome in Graft Versus Host Disease
Payen, M., & Rousseau, C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815249-2.00039-7
Antimicrobial Drug Prophylaxis: Challenges and Controversies
Trikha, G., Nucci, M., Wingard, J. R., & Safdar, A. (2019) · Springer eBooks · doi:10.1007/978-1-4939-9034-4_65
Microbial-Based Cancer Therapy: Diagnostic Tools and Therapeutic Strategies
Malik, S. S., Masood, N., Fatima, I., & Kazmi, Z. (2019) · Microorganisms for sustainability · doi:10.1007/978-981-13-8844-6_3
Papel da obesidade na rejeição ao transplante de pele experimental
Terra, F. F. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2019.tde-16122019-155621
The Effect of Intestinal Microbiome on the Effectiveness of Antitumor Immunotherapy
Olekhnovich, E. I., Manolov, A. I., Pavlenko, A. V., Konanov, D. N., Fedorov, D. E., Tikhonova, P., Glushchenko, O. E., & Ilina, E. N. (2020) · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry · doi:10.1134/s1990750820030105
Another Reason to Eat More Apples and Whole Grain: How Inflammation and Hematopoiesis are Affected by Dietary Fiber and GI Microbes
Vercellotti, G. M. (2014) · The Hematologist · doi:10.1182/hem.v11.3.2752
The microbiome—the revealing of a long time unbeknownst factor for outcome in murine models of graft-versus-host disease
Kumari, R., Palaniyandi, S., & Hildebrandt, G. C. (2021) · Bone Marrow Transplantation · doi:10.1038/s41409-021-01325-7
Impact of Conditioning Regimen Choice: The Role of Dendritic Cells in Graft-Versus-Host Disease
Molina, M. S. (2021) · UA Campus Repository (The University of Arizona)
Cancer Microbiome and Immunotherapy: Understanding the Complex Responses Between Microbes, Immunity, and Cancer
Godisela, K. K., Kiran, B. S. S., & Bramhachari, P. V. (2021) · Springer eBooks · doi:10.1007/978-981-16-3156-6_6
Fecal Microbiota Transplantation as a Novel Method of Multidrug-Resistant Infections Treatment in Allogeneic Hematopoietic Stem Cell Transplantation Recipients
Kucher, М. A., Goloshchapov, O. V., Suvorova, M. A., Klementeva, R. V., Щербаков, А. А., Shvetcov, A. N., Kazantsev, I. V., Moiseev, I., Zubarovskaya, L. S., & Afanasyev, B. V. (2020) · Transplantation Research Journal · doi:10.16966/2473-1730.117
Impacto do uso de Lactobacilus plantarum na colonização, na infecção por bactérias multirresistentes e no microbioma de pacientes submetidos a transplante de células tronco hematopoiéticas
Moraes, B. D. G. D. C. (2021) · doi:10.11606/d.5.2021.tde-06122021-103022
The Human Gut Microbiota-Lymphocyte Crosstalk
Millet-Boureima, C., Petraccione, K., Nibar, S. G., Hight, R., Caudle, W., Countiss, T., Drouin, A., Duda, M., Earley, M., Finn, R. A., et al. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-819265-8.00113-3
Faculty Opinions recommendation of IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice.
Saas, P., & Chagué, C. (2021) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.739503818.793582840
ACUTE GVHD TRIGGERED BY COVID-19 IN A BONE MARROW RECIPIENTPreprint
Gözmen, S., & Devrim, İ. (2022) · doi:10.22541/au.164864637.74673917/v1
GPR109A in GVHD: friend or foe?
Toubai, T. (2022) · Blood · doi:10.1182/blood.2021014128
New insight into pathophysiology and treatment of GVHD
Ara, T., & Hashimoto, D. (2022) · Japanese Journal of Transplantation and Cellular Therapy · doi:10.7889/tct-22-001
Faculty Opinions recommendation of Lactose drives Enterococcus expansion to promote graft-versus-host disease.
Saas, P., Chagué, C., & Daguindau, É. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.736996728.793570749
Faculty Opinions recommendation of Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation.
Tillotson, G. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.737439922.793571921
Role of Bradyrhizobium enterica in gastrointestinal graft-versus-host disease
Selim, C., Tellı, M., Bolaman, Z., & Yavaşoğlu, İ. (2022) · Acta Haematologica Polonica · doi:10.5603/ahp.a2022.0028
Supplemental N-acyl homoserine lactonase alleviates intestinal disruption and improves gut microbiota in broilers challenged by Salmonella typhimuriumPreprint
Wang, W., Ou, J., Ye, H., Cao, Q., Zhang, C., Dong, Z., Feng, D., & JianJun, Z. (2022) · Research Square · doi:10.21203/rs.3.rs-1717877/v1
Nutritional Management of Children With Cancer
(2020) · American Academy of PediatricsItasca, IL eBooks · doi:10.1542/9781610023610-41
Dynamics of gut microbiota in patients suffering from hematologic malignancies after allogeneic hematopoi-etic stem cell transplantation
Akhremchuk, K. U., Skapavets, K. Y., Akhremchuk, A. E., Kirsanava, N., Sidarenka, A. V., & Valentovich, L. N. (2022) · Experimental Biology and Biotechnology · doi:10.33581/2957-5060-2022-2-48-59
Early immunomodulatory program triggered by pro-tolerogenic Bifidobacterium pseudolongum drives cardiac transplant outcomesPreprint
Gavzy, S. J., Kensiski, A., Saxena, V., Lakhan, R., Hittle, L. E., Wu, L., Iyyathurai, J., Dhakal, H., Lee, Z. L., Li, L., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.13.511915
Reply to de Mooij et al
Rashidi, A., Peled, J. U., & Staley, C. M. (2022) · Clinical Infectious Diseases · doi:10.1093/cid/ciac888
Il ruolo del microbiota intestinale nella modulazione immunitaria
Leardini, D., Muratore, E., Zama, D., Prete, A., Pession, A., & Masetti, R. (2020) · Medico e Bambino - Pagine Elettroniche · doi:10.53126/mebxxiiig130
Microbiome in Pancreatic Cancer
Chandra, V., & McAllister, F. M. (2022) · Springer eBooks · doi:10.1007/978-3-031-05724-3_23
Gut Microbiome in Hematopoietic Stem Cell Transplantation Patients: Current State of Research and Results of Pilot Clinical Study
Стома, И. О., Миланович, Н. Ф., Усс, М. А., & Moduleva, E. A. (2021) · ВЕСТНИК ОБРАЗОВАНИЯ И РАЗВИТИЯ НАУКИ РОССИЙСКОЙ АКАДЕМИИ ЕСТЕСТВЕННЫХ НАУК · doi:10.26163/raen.2021.38.38.015
Systemic Onco-Sphere: Host Microbiome and Cancer
Saw, P. E., & Song, E. (2023) · Springer eBooks · doi:10.1007/978-981-99-1183-7_25
Mucositis and dysbiosis of the oral microbiome and fecal microbial flora in pediatric and young adult patients undergoing allogeneic Hematopoietic Stem Cell TransplantationPreprint
Faraci, M., Bonaretti, C., Dell’Orso, G., Pierri, F., Giardino, S., Angiero, F., Blasi, S., Farronato, G., Marco, E. D., Trevisiol, A., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-3220087/v1
Nutritional Management of Children With Cancer
(2020) · American Academy of PediatricsItasca, IL eBooks · doi:10.1542/9781610024181-41
The Significance of the Intestinal Microbiome in Hematopoietic Stem Cell Transplantation
Ara, T., & Hashimoto, D. (2023) · Japanese Journal of Transplantation and Cellular Therapy · doi:10.7889/tct-23-022
Acute Steroid-Refractory Gastrointestinal Graft-Versus-Host Disease Is Not Associated With Significant Differences in Gut Taxonomic Composition Compared to Steroid-Sensitive Gastrointestinal Graft-Versus-Host Disease Immediately Before Onset of Disease
Zeng, K., Brewster, R., Kang, J. B., Tkachenko, E., Brooks, E. F., Bhatt, A. S., Fodor, A. A., & Andermann, T. M. (2023) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2023.11.006

Authors: Jenq, R. R., Ubeda, C., Taur, Y., Menezes, C. C., Khanin, R., Dudakov, J. A., Liu, C., West, M. L., Singer, N. V., Equinda, M. J., Gobourne, A., Lipuma, L., Young, L. F., Smith, O. M., Ghosh, A., Hanash, A. M., Goldberg, J. D., Aoyama, K., Blazar, B. R., Pamer, E. G., & R.M. van den Brink, M.
Affiliations: Memorial Sloan Kettering Cancer Center (US)
Adult Bone Marrow Transplantation Service 1 and 2 ; and 3
Cornell University (US)
University of Florida (US)
University of Minnesota (US)
Corresponding author: Jenq, Robert R.
ORCID: Jenq, Robert R.
Taur, Ying
Dudakov, Jarrod A.
Liu, Chen
Lipuma, Lauren
Young, Lauren F.
Ghosh, Arnab
Hanash, Alan M.
Blazar, Bruce R.
Pamer, Eric G.
Venue: Journal of Experimental Medicine
Publisher: Rockefeller University Press
Published: 2012-04-30
Volume: 209
Issue: 5
Pages: 903-911
ISSN: 0022-1007 (ISSN-L)
1540-9538
DOI: 10.1084/jem.20112408
PMC: PMC3348096
OpenAlex: W2131766513
Cited by: 626
References: 37
Citations by year: 2026: 15 · 2025: 35 · 2024: 23 · 2023: 45 · 2022: 55 · 2021: 53 · 2020: 58 · 2019: 48 · 2018: 51 · 2017: 67 · 2016: 61 · 2015: 40 · 2014: 43 · 2013: 22 · 2012: 10
FWCI: 14.69
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: cc-by-nc-sa
Locations: The Journal of Experimental Medicine (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
PubMed Central (publishedVersion, cc-by-nc-sa)
PubMed (publishedVersion)
Funders: National Institutes of Health (UL1TR000064, 4r37ai039031-21, 5k23ai095398-05)
National Heart, Lung, and Blood Institute (R01HL056067, R01HL069929)
National Cancer Institute (P01CA023766, P01CA142106, R01CA107096, P30CA008748)
National Institute of Allergy and Infectious Diseases (R01AI034495, R37-AI039031, R01AI100288, R01AI080455, K23-AI095398, P01AI056299, R01AI042135)
National Center for Advancing Translational Sciences
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords: intestinal inflammation, gut microbiota, allogeneic bone marrow transplantation, graft-versus-host disease, Lactobacillus, Lactobacillales, Clostridiales, microbial diversity, microbiome manipulation, gut microbiota composition
MeSH terms: Ampicillin, Animals, Base Sequence, Enterocolitis, Feces, Graft vs Host Disease, Gram-Positive Bacteria, Humans, Molecular Sequence Data, Phylogeny, RNA, Ribosomal, 16S, Species Specificity, Transplantation, Homologous, Bone Marrow Transplantation, Dextran Sulfate, Sequence Analysis, DNA, Biodiversity, Mice, Metagenome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks